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基于超声图像的直方图分析在睾丸良恶性病变鉴别诊断中的价值

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中国超声医学杂志 2024年第3期40卷 324-327页

作者：苏唤忠洪龙城黄美苏毅明张佐炳张晓东厦门大学附属第一医院超声影像科

目的探讨基于超声图像的直方图分析在睾丸良恶性病变鉴别诊断中的可行性和价值。方法回顾性分析经病理证实的70例睾丸病变患者的超声图像，根据病理结果分为良性组(23例)和恶性组(47例)。基于超声医师手工勾画的感兴趣区进行直方图分... 详细信息

目的探讨基于超声图像的直方图分析在睾丸良恶性病变鉴别诊断中的可行性和价值。方法回顾性分析经病理证实的70例睾丸病变患者的超声图像，根据病理结果分为良性组(23例)和恶性组(47例)。基于超声医师手工勾画的感兴趣区进行直方图分析，计算均值、方差、偏度、峰度、不同百分位数(P1、P10、P50、P90、P99)。对良恶性组的直方图参数进行比较，并用多因素Logistic回归分析筛选独立影响因素。绘制受试者工作特征(ROC)曲线评价直方图参数的鉴别诊断效能。结果良性组的方差、偏度、P99明显高于恶性组(P0.05)。多因素Logistic回归分析结果显示，方差及偏度是鉴别睾丸良恶性病变的独立影响因素。ROC曲线结果显示，方差、偏度、P10、P50、P99鉴别诊断的曲线下面积(AUC)为0.693～0.839;方差及偏度联合鉴别诊断的AUC为0.910(95%CI:0.838～0.982)。结论基于超声图像的直方图分析是鉴别睾丸良恶性病变的一个有潜能的工具，其中方差及偏度的联合诊断价值最高。

关键词：超声图像直方图分析睾丸病变鉴别诊断

Electronic Properties of Solid Composed of Al_(12)Ge Clusters

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Chinese Physics Letters 1998年第2期15卷 103-105页

作者： ZHU Zi-zhong TIAN Bo huang mei-chun Department of Physics Xiamen UniversityXiamen 361005

The ab initio pseudopotential local-density studies on the electronic structure and geometry of a theoretical solid are presented with Al_(12)Ge cluster serving as the building block of the *** results show that bulk material formed from cubic close-packing of All2Ge clusters will eventually be an aluminum-like metal when lattice parameter of the solid and atomic geometry of the clusters are optimized by the crystal field.

关键词： material. field. geometry

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面向公差原则的装配体公差优化分配

机械设计与制造 2024年第8期402卷 152-155页

作者：程彬彬黄美发庞静娜刘朝福桂林信息科技学院机电工程学院广西桂林541004 桂林电子科技大学机电工程学院广西桂林541004 广西盛丰建设集团有限公司广西桂林541001

针对现有装配体公差优化分配中没有考虑公差原则影响的问题,将公差原则引入到装配体公差优化分配模型中,为面向公差原则的装配体公差优化分配提供一种可行的方法。首先,以公差原则修正后的雅可比旋量模型为基础,构建装配体公差优化分配... 详细信息

针对现有装配体公差优化分配中没有考虑公差原则影响的问题,将公差原则引入到装配体公差优化分配模型中,为面向公差原则的装配体公差优化分配提供一种可行的方法。首先,以公差原则修正后的雅可比旋量模型为基础,构建装配体公差优化分配模型的装配功能约束;其次,结合实际机械加工精度范围,构建装配体公差优化分配模型的加工能力约束;然后,根据公差成本函数,构建装配体公差优化分配模型的优化目标;最后,以机床尾座为实例说明了面向公差原则的装配体公差优化分配过程,采用遗传算法求解,对装配体公差优化分配结果进行了分析,验证了该方法的有效性。

关键词：雅可比旋量模型公差优化分配公差原则公差成本函数

Epidemiologic features of Kawasaki disease in Shanghai from 2003 through 2007

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Chinese Medical Journal 2010年第19期123卷 2629-2634页

作者： MA Xiao-jing YU Cen-yan huang Min CHEN Shu-bao huang mei-rong huang Guo-ying Children's Hospitai of Fudan University Shanghai 201102 China Children's Hospital of Shanghai Jiao Tong University Shanghai 200040 China Shanghai Children's-Medical Center Shanghai 200127 China Xinhua Hospital of Shanghai Jiao Tong University Shanghai 200092 China Institute of Biomedical Science Fudan University Shanghai 200032 China Pediatric Heart Center Children's Hospital of Fudan University 399 Wan Yuan Road Shanghai 201102 China

Background The epidemiologic pictures of Kawasaki disease （KD） in Shanghai from 1998 through 2002 were reported while the current status of KD in the following five years remains unknown. Methods A questionnaire form and diagnostic guidelines for KD were sent to 50 hospitals providing pediatric medical care in Shanghai, China. All patients with KD diagnosed during January 2003 through December 2007 were recruited. Results In total, 1187 cases of KD were enrolled. The incidence of KD was 36.78 to 53.28 （mean 46.32±6.51） per 100 000 children under the age of 5 years between 2003 and 2007, which was higher than the year from 1998 to 2002 of （27.32±7.11） per 100 000, （t=4.406, P=0.002）. Ages at onset ranged from 12 days to 13.6 years （median 1.8 years）. It occurred more frequently in summer and spring. Coronary arterial lesions （CAL）, defined as ectasia or aneurysm, accounted for 19.8% （232 cases）. Flattened or inverted T wave was the most frequent finding （194 cases, 20.5%） by electrocardiogram. Intravenous gamma-globulin was administrated to 1028 cases （86.6%）. The occurrence of CAL seemed less frequent in the patients received gamma-globulin from day 5 to day 9 after the onset with the regimen of 1000 mg/kg once or 1000 mg/kg twice. Conclusions The incidence of KD was increasing in Shanghai. Treatment with intravenous gamma-globulin from day 5 to day 9 after the onset with the regimen of 1000 mg/kg once or 1000 mg/kg twice resulted in less coronary seauelae.

关键词： Kawasaki disease mucocutaneous lymph node syndrome coronary arterial lesions epidemiology incidence

A software architecture centric engineering approach for Internetware

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Science in China(Series F) 2006年第6期49卷 702-730页

作者： mei Hong huang Gang ZHAO Haiyan JIAO Wenpin School of Electronics Engineering and Computer Science Peking University Beijing 100871 China

As a new software paradigm evolved by the Internet, Internetware brings many challenges for the traditional software development methods and techniques. Though architecture-based component composition （ABC） approach is originated in the traditional software paradigm, it supports the engineering of Internetware effectively due to its philosophy, rationales and mechanisms. ABC has three major contributions to the en- gineering of Internetware in detail. First, the feature oriented domain modeling method can structure the ＂disordered＂＂software entities＂ to ＂ordered Internetware＂ bottom-up in the problem space. Second, the architecture centric design and analysis method can support the development of self-adaptive Internetware. Third, the component operating platform is a reflective and self-adaptive middleware that not only provides Internetware with a powerful and flexible runtime infrastructure but also enables the self-adaptation of the structure and individual entities of Internetware.

关键词： internetware component software architecture feature model reflective middleware autonomous component

BLOCK-TRIANGULAR PRECONDITIONERS FOR SYSTEMS ARISING FROM EDGE-PRESERVING IMAGE RESTORATION

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Journal of Computational Mathematics 2010年第6期28卷 848-863页

作者： Zhong-Zhi Bai Yu-mei huang Michael K. Ng LSEC ICMSEC Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing 100190 China School of Mathematics and Statistics Lanzhou University Lanzhou 730000 China Department of Mathematics Hong Kong Baptist University Kowloon Tong Hong Kong

Signal and image restoration problems are often solved by minimizing a cost function consisting of an l2 data-fidelity term and a regularization term. We consider a class of convex and edge-preserving regularization functions. In specific, half-quadratic regularization as a fixed-point iteration method is usually employed to solve this problem. The main aim of this paper is to solve the above-described signal and image restoration problems with the half-quadratic regularization technique by making use of the Newton method. At each iteration of the Newton method, the Newton equation is a structured system of linear equations of a symmetric positive definite coefficient matrix, and may be efficiently solved by the preconditioned conjugate gradient method accelerated with the modified block SSOR preconditioner. Our experimental results show that the modified block-SSOR preconditioned conjugate gradient method is feasible and effective for further improving the numerical performance of the half-quadratic regularization approach.

关键词： Block system of equations Matrix preconditioner Edge-preserving Image restoration Half-quadratic regularization.

Transcatheter arterial chemoembolization combined with CT-guided percutaneous thermal ablation versus hepatectomy in the treatment of hepatocellular carcinoma

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Chinese Journal of Cancer 2015年第6期34卷 29-38页

作者： Sheng Li Liang Zhang Zhi-mei huang Pei-Hong Wu Department of Medical Imaging & Interventional Radiology Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China Col aborative Innovation Center for Cancer Medicine

Introduction:Transcatheter arterial chemoembolization(TACE)plus thermal ablation has been widely used recently in the treatment of hepatocellular carcinoma(HCC).In this study,we aimed to compare results of the combination of TACE and percutaneous thermal ablation with those of hepatectomy in patients with ***:The clinical data of 137 HCC patients who sequentially received TACE and computed tomography(CT)-guided percutaneous thermal ablation as an initial curative treatment(combination group)and 148 matched HCC patients who received hepatectomy(surgery group)between 2004 and 2011 were collected and *** TACE,multiphase contrast-enhanced CT was performed to identify the total number of tumors as well as lipiodol deposition in the *** was calculated by using the Kaplan-meier method and compared by using the log-rank *** prognostic factors were assessed with multivariate Cox proportional hazards regression ***:Of all 285 patients,225(79.0%)had cancerous lesions≤5 cm in *** preoperative contrast-enhanced CT or magnetic resonance imaging,the number of tumors was 1–4 for each *** 1-,3-,and 5-year overall survival rates were 95,74%,and 67%in the combination group and 88,66,and 47%in the surgery group,respectively(P=0.004);the corresponding recurrence-free survival rates for the two groups were 92,69,and 61%and 75,58,and44%,respectively(P=0.001).In the multivariate analysis,treatment allocation was an independent prognostic factor for *** 60 patients in the combination group had sufficient imaging data,and 135 new lesions with lipiodol deposition were diagnosed as malignancies in 22 of 60 patients,whereas 20 new lesions were found in 11 of 148patients in the surgery ***:The combination of TACE and CT-guided percutaneous thermal ablation for HCC improves survival of HCC patients compared with hepatectomy.

关键词：原发性肝癌切除术肝动脉治疗 CT 引导计算机断层扫描肝细胞癌

HL-3装置电子回旋共振加热系统中上斜一号天线光路的改进与测试

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核聚变与等离子体物理 2024年第3期44卷 256-261页

作者：郑万欣叶际若陈罡宇张峰黄梅核工业西南物理研究院

针对HL-3装置等离子体实验的不同目的，为电子回旋共振加热系统设计了3组发射天线，其中上斜一号天线包含两束微波，其主要功能是控制MHD的不稳定性及实时抑制新经典撕裂模(NTM)。要实时控制与抑制NTM不稳定性，需要依靠天线快速改变注... 详细信息

针对HL-3装置等离子体实验的不同目的，为电子回旋共振加热系统设计了3组发射天线，其中上斜一号天线包含两束微波，其主要功能是控制MHD的不稳定性及实时抑制新经典撕裂模(NTM)。要实时控制与抑制NTM不稳定性，需要依靠天线快速改变注入角度，向磁岛位置发射微波。针对之前光路设计存在的问题，对上斜一号天线聚焦镜进行了重新设计，并完成了加工制造。在光线测试平台使用激光模拟微波，测试了此天线的性能。经测试天线左右两电机在满量程(入射角度-15°～-80°)运行时的最快变化时间分别为189.875ms和189.5ms。测试结果表明，天线控制精确、快速，达到了装置实验使用的要求。

关键词： HL-3装置天线聚焦镜电机

Elastic, dynamical, and electronic properties of LiHg and Li3Hg： First-principles study

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Frontiers of physics 2018年第2期13卷 111-117页

作者： Yan Wang Chun-mei Hao Hong-mei huang Yan-Ling Li School of Physics and Electronic Engineering Jiangsu Normal University Xuzhou 221116 China

The elastic, dynamical, and electronic properties of cubic LiHg and Li3Hg were investigated based on first-principles methods. The elastic constants and phonon spectral calculations confirmed the mechanical and dynamical stability of the materials at ambient conditions. The obtained elastic moduli of LiHg are slightly larger than those of Li3Hg. Both LiHg and Li3Hg are ductile materials with strong shear anisotropy as metals with mixed ionic, covalent, and metallic interactions. The calculated Debye temperatures are 223.5 K and 230.6 K for LiHg and Li3Hg, respectively. The calculated phonon frequency of the T2g mode in Li3Hg is 326.8 cm-1. The p states from the Hg and Li atoms dominate the electronic structure near the Fermi level. These findings may inspire further experimental and theoretical study on the potential technical and engineering applications of similar alkali metal-based intermetallic compounds.

关键词： Li-Hg alloys elastic property phonon spectrum electronic structure