检索结果-南通市图书馆

NEURAL NETWORK ANALYSIS APPLICATION TO PERMEABILITY DETERMINATION OF FIBERGLASS AND CARBON PREFORMS

Chinese Journal of Polymer Science 2009年第2期27卷 221-229页

作者： Hossein Golestanian mehrdad poursina Mechanical Engineering Group Faculty of EngineeringUniversity of ShahreKordShahreKord ***Iran

Preform permeability is an important process parameter in liquid injection molding of composite *** parameter is currently determined with time consuming and expensive experimental *** paper presents the application of a back-propagation neural network to predicting fiber bed permeability of three types of reinforcement mats. Resin flow experiments were performed to simulate the injection cycle of a resin transfer molding *** results of these experiments were used to prepare a training set for the back propagation neural network *** reinforcements consisted of plain-weave carbon,plain-weave fiberglass,and chopped fiberglass *** effects of reinforcement type, porosity and injection pressure on fiber bed permeability in the preform principal directions were ***,in the training of the neural network reinforcement type,these process parameters were used as the input *** bed permeability values were the specified output of the *** a result of the specified parameters,the program was able to estimate fiber bed permeability in the preform principal directions for any given processing *** results indicate that neural network may be used to predict preform permeability.

关键词： Artificial neural network Permeability Porosity Resin transfer molding.

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Simplified microsatellite instability detection protocol provides equivalent sensitivity to robust detection strategies in Lynch syndrome patients

引用

Cancer Biology & Medicine 2017年第2期14卷 142-150页

作者： Hadi Babaei mehrdad Zeinalian Mohammad Hassan Emami Mortaza Hashemzadeh Najmeh Farahani Rasoul Salehi Department of Genetics and Molecular Biology School of MedicineIsfahan University of Medical Sciences Clinic of Gastrointestinal Diseases Poursina Hakim Research CenterIsfahan University of Medical Sciences Cellular and Molecular Research Center Shahrekord University of Medical Sciences

Objective:Germline mutations in mismatch repair(MMR)genes cause Lynch syndrome(LS).LS is an inherited disease,and an important consequence of MMR deficiency is microsatellite instability(MSI)*** phenotype influences the efficacy of5 fluorouracil(5-FU)***,cost effective,and easy to perform laboratory tests are required to include MSI detection in routine laboratory *** of CAT25 as monomorphic short tandem repeat sequence enables CAT25 to be an efficient screening tool among hereditary nonpolyposis colorectal cancer(HNPCC)patients compared with other methods used ***:Based on Amsterdam II criteria,31 patients in 31 families were shortlisted from a total number of 1,659 colorectal cancer *** status was examined in these patients using CAT25 and a commercially available Promega MSI five-markerbased detection system as well as immunohistochemical(IHC)staining of four important MMR *** were scored as high microsatellite instable(MSI-H),low(MSI-L),or stable(MSS).MSI status determined by CAT25 single mononucleotide marker was compared with that of five mononucleotide markers,Promega commercial kit,and IHC ***:MMR protein deficiency was observed on 7/31 probands using IHC methodology and 6/31 categorized as MSI-H using commercial kit or CAT25 single *** sensitivity and specificity of the CAT25 single marker were the same as those detected by five-marker Promega commercial kit in our ***:Based on our results,the performance of the CAT25 single mononucleotide marker for MSI status determination in our HNPCC patients is the same as that of the five-marker-based commercial kit.

关键词： Lynch syndrome HNPCC DNA mismatch repair IHC microsatellite instability

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：