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Summary of the current guidelines for managing iatrogenic colorectal perforations and the evolving role of endoluminal vacuum therapy

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World Journal of Clinical Cases 2025年第6期13卷 1-8页

作者： Ahmed Tawheed Ibrahim Halil Bahcecioglu mehmet yalniz Mubin Ozercan Ali Cagri Oral Mohamed El-Kassas Department of Endemic Medicine Faculty of MedicineHelwan UniversityCairo 11795Egypt Department of Gastroenterology Firat UniversityElazig 23119Türkiye Liver Disease Research Center College of MedicineKing Saud UniversityRiyadh 7805Saudi Arabia

Colonoscopy represents a safe procedure that is widely used in medical practice either to diagnose or treat various gastrointestinal *** the last few years,the incidence rate of perforations in colonoscopic procedures has increased,especially in therapeutic *** recent advancements in endoscopic techniques and gastrointestinal tumoral resection procedures such as endoscopic mucosal resection,endoscopic full-thickness resection,and endoscopic submucosal dissection(ESD)could be a risk factor for this increased *** incidence rate of mortality of serious colonoscopic perforations is 7.1%.The management plan for these perforations starts with conservative treatment in mild cases,endoscopic closure,and surgical management in severe ***,endoluminal vacuum therapy was found to be effective in the management of colorectal perforations and this has been reported in multiple case *** editorial provides an overview of the current guidelines for the management of iatrogenic colorectal *** insights are from the perspectives of endoscopists and *** also present a management algorithm based on the guidelines of the European Society of Gastrointestinal Endoscopy,the American Gastroenterological Association,and the World Society of Emergency *** also discussed in brief the use of endoluminal vacuum therapy in colorectal perforations.

关键词： Colon Rectum Iatrogenic colonic perforation Colonoscopy Guidelines Endovacuum Endolumical vacuum therapy Endoscopic management

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Gastroesophageal reflux after per-oral endoscopic myotomy:Management literature

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World Journal of Gastroenterology 2024年第23期30卷 2947-2953页

作者： Ahmed Tawheed Ibrahim Halil Bahcecioglu mehmet yalniz Mohamed El-Kassas Department of Endemic Medicine Faculty of MedicineHelwan UniversityCairo 11795Egypt Department of Gastroenterology Faculty of MedicineFirat UniversityElazig 23119Türkiye Liver Disease Research Center College of MedicineKing Saud UniversityRiyadh 7805Saudi Arabia

In this editorial,we respond to a review article by Nabi et al,in which the authors discussed gastroesophageal reflux(GER)following peroral endoscopic myotomy(POEM).POEM is presently the primary therapeutic option for achalasia,which is both safe and effective.A few adverse effects were documented after POEM,including *** diagnostic criteria were not clear enough because approximately 60%of patients have a long acid exposure time,while only 10%experience reflux *** predictors of high disease incidence have been identified,including old age,female sex,obesity,and a baseline lower esophageal sphincter pressure of less than 45 *** technical steps during the procedure,such as a lengthy or full-thickness myotomy,may further enhance the *** pump inhibitors are currently the first line of *** voices are increasingly advocating for the routine combining of POEM with an endoscopic fundoplication method,such as peroral endoscopic fundoplication or transoral incisionless ***,more research is necessary to determine the safety and effectiveness of these procedures in the long term for patients who have undergone them.

关键词： Achalasia Per-oral endoscopic myotomy Gastroesophageal reflux disease Transoral incisionless fundoplication Peroral endoscopic fundoplication

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Relationship between serum cytokine levels and histopathological changes of liver in patients with hepatitis B

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World Journal of Gastroenterology 2005年第21期11卷 3260-3263页

作者： Nusret Akpolat Seyfettin Yahsi Ahmet Godekmerdan Kutbettin Demirbag mehmet yalniz Departments of Pathology Faculty of Medicine Firat University ElazigTurkey Departments of Immunology Faculty of Medicine Firat UniversityElazigTurkey Departments of Infection Diseases Faculty of Medicine Firat University Elazig Turkey Departments of Gastroenterology Faculty of Medicine Firat University Elazig Turkey

AIM: To investigate whether there was a relationship between the liver functions and fibrosis scores of hepatitis B patients and their TNF-α, IFN-γ,IL-4, and TGF-β1 serum levels based on the studies of liver biopsies. METHODS: Thirty patients with chronic hepatitis B (CHB) receiving no treatment and 30 healthy individuals with negative hepatitis serology and normal values of liver biochemistry were studied. After serum samples of the patients were collected, liver needle biopsy was performed on each patient. Cytokine levels were studied by ELISA. The biopsy materials were scored based on Knodell's histological activity index. RESULTS: In comparison of cytokine levels between CHB patients and control group, TNF-α,IL-4, and TGPβ1 levels of the patients were higher in CHB patients than in the controls, while IFN-γ level was lower in the patients than in the controls. There were significant differences between the groups in TNF-α, IL-4, TGF-β1, and IFN-γ(P0.05). TGF-β1 was correlated with fibrosis (P0.05). CONCLUSION: In the course of HBV infection and its chronic progress, cytokines play an important role. IL-4 and IFN-γ are effective in the chronic progression, while TGF-β1 is effective in the development of fibrosis. Serum cytokine levels may be effective tools in the estimation of chronic progression and fibrosis development.

关键词： Hepatitis B Cytokine

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Fuzzy rule based seismic risk assessment of one-story precast industrial buildings

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Earthquake Engineering and Engineering Vibration 2019年第3期18卷 631-648页

作者： mehmet Palanci Istanbul Arel University Department of Civil Engineering

Effi cient tools capable of using uncertain data to produce fast and approximate results are more practical in rapid decision-making applications when compared to conventional methods. From this point of view, this study introduces a risk assessment model for one-story precast industrial buildings by fuzzy logic which builds a bridge between uncertainty and precision. The input, output and relations of the fuzzy based risk assessment model (FBRAM) were determined by reference buildings. The Monte Carlo simulation method was used to handle uncertainties associated with the structural characteristics of the reference buildings. Section dimension, longitudinal reinforcement ratio, column height related to building elevation, confi nement ratio and seismic hazard are regarded as input and the plastic demand ratio is considered as the output parameter by the mathematical formulation of strength and deformation capacity of the buildings. The supervised learning method was used to determine the membership function of fuzzy sets. Fuzzy rules of FBRAM were constructed from Monte Carlo simulation by mapping of inputs and output. FBRAM was evaluated by a group of simulated buildings and two existing precast industrial buildings. Comparisons have shown signifi cant agreement with analytical model results in both cases. Consequently, it is anticipated that the proposed model can be used for the seismic risk mitigation of precast buildings.

关键词： fuzzy logic supervised learning precast buildings risk assessment Monte Carlo simulation

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Two-and three-dimensional stability analysis of underground storage caverns in soft rock(Cappadocia, Turkey) by finite element method

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Journal of Mountain Science 2022年第4期19卷 1182-1202页

作者： SARI mehmet Department of Mining Engineering Aksaray UniversityAksaray 68100Turkey

Engineering design in soft rocks and its stability analysis exerts many challenges to rock engineers. Many engineering works in Turkey’s Cappadocia region must face and tackle the existing sites covered by the soft rocks. This study is aimed to examine the stability condition of a typical underground storage cavern(USC) excavated in a soft rock in this region. For this purpose, two-and threedimensional stability analyses of the USCs were performed using the finite element method(FEM).Because of the inherent difficulty in characterizing soft/weak rock masses in the region using traditional classification systems, the stability of a typical USC was evaluated by representing the rock mass condition with two distinct scenarios in FEM *** these structures were unstable according to the 2D analysis conducted in RS2 software in the worstcase scenario, they were stable in the 3D analysis using RS3 software in both scenarios. Besides,feasible cover depths were examined to assess their possible effects on the factor of safety and deformation measurements. It was found that 15 m seems to be an optimal depth for excavating a typical USC in the soft rocks exposed in the region. The 3D FEM results provide valuable information to optimize the future planning and preliminary design of USCs.

关键词： Underground storage cavern Numerical modeling Soft rock FEM analysis Rock mass failure

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Evaluating rockfalls at a historical settlement in the Ihlara Valley(Cappadocia, Turkey) using kinematic, numerical, 2D trajectory, and risk rating methods

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Journal of Mountain Science 2022年第12期19卷 3346-3369页

作者： SARI mehmet Department of Mining Engineering Aksaray UniversityAksaray68100Turkey

Rockfalls are one of the most dangerous natural events in hilly terrains, and they substantially threaten residential areas and transport corridors in these environments. This study is aimed to analyze the risk of rockfall from a slope to nearby houses in a historical settlement with past rockfall histories. It contains numerous applications to study rockfall danger from different points of view(e.g., kinematics,numerical stability analysis, risk assessment, 2D trajectory). The rockfall kinematics revealed the statistics for different structurally controlled failure modes among the surveyed slope discontinuities,especially wedge type and block toppling were the most significant ones. Finite element analysis showed that the slope was stable under the natural condition with a safety factor of 2.19. The rockfall risk rating system calculated a medium risk for the houses downstream. Based on the field measurements, a possible rockfall profile was determined and located as an input in the 2D rockfall trajectory program. The rigid-body impact model runs utilized various shapes and sizes of blocks to simulate the rockfall events realistically. According to the 2D trajectory model results, there was no rockfall danger for the investigated downslope houses. The study showed the importance of using different analysis techniques to solve rockfall risk in protected areas based on scientific and rational approaches.

关键词： Belisirma village Cappadocia region Rockfall kinematics 2D rockfall trajectory analysis Rockfall risk rating system FEM modeling

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Analytical and approximate solutions of(2+1)-dimensional time-fractional Burgers-Kadomtsev-Petviashvili equation

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Communications in Theoretical Physics 2020年第5期72卷 21-31页

作者： mehmet Senol Department of Mathematics Nevsehir Haci Bektas Veli UniversityNevsehirTurkey

In this paper,we applied the sub-equation method to obtain a new exact solution set for the extended version of the time-fractional Kadomtsev-Petviashvili equation,namely Burgers-Kadomtsev-Petviashvili equation(Burgers-K-P)that arises in shallow water ***,using the residual power series method(RPSM),approximate solutions of the equation were obtained with the help of the Mathematica symbolic computation *** also presented a few graphical illustrations for some *** fractional derivatives were considered in the conformable *** of the obtained solutions were replaced back in the governing equation to check and ensure the reliability of the *** numerical outcomes confirmed that both methods are simple,robust and effective to achieve exact and approximate solutions of nonlinear fractional differential equations.

关键词： fractional partial differential equations Burgers-Kadomtsev-Petviashvili equation conformable fractional derivative sub-equation method residual power series method

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Optimization of selective copper extraction from chalcopyrite concentrate in presence of ammonium persulfate and ammonium hydroxide

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International Journal of Minerals,Metallurgy and Materials 2019年第8期26卷 946-952页

作者： mehmet Deniz Turan Department of Metallurgical and Materials Engineering Firat University

The dissolution of copper and iron from chalcopyrite concentrate in the presence of ammonium persulfate(APS)and ammonium hydroxide was investigated under atmospheric leaching *** were designed by central composite design(CCD).Under the optimum leaching conditions((NH4)2S2O8 concentration=328 g/L;NH4OH addition=16vol%;leaching temperature=321 K(48℃);leaching time=120 min;liquid-to-solid ratio=16;stirring speed=400 r/min),selective leaching was achieved.98.14%of the copper was leached,whereas iron did not pass into the solution.X-ray diffraction analysis of the leaching residue showed that iron compounds were *** the leaching results,the fact that the leaching process does not include uneconomical leaching stages such as extended milling/mechanical activation or high pressures/temperatures,and the low copper dissolution conditions,the attained selective leaching yield may be remarkable.

关键词： leaching complex reaction selectivity copper chalcopyrite

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Reductive atmospheric acid leaching of spent alkaline batteries in H_2SO_4/Na_2SO_3 solutions

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International Journal of Minerals,Metallurgy and Materials 2015年第7期22卷 674-681页

作者： mehmet Hakan Morcali Faculty of Chemical and Metallurgical Engineering Istanbul Technical University

This work studies the optimum reductive leaching process for manganese and zinc recovery from spent alkaline battery paste. The effects of reducing agents, acid concentration, pulp density, reaction temperature, and leaching time on the dissolution of manganese and zinc were investigated in detail. Manganese dissolution by reductive acidic media is an intermediate-controlled process with an activation energy of 12.28 kJ＇mo1-1. After being leached, manganese and zinc were selectively precipitated with sodium hydroxide. The zinc was entirely con- verted into zincate （Zn（OH）42-） ions and thus did not co-precipitate with manganese hydroxide during this treatment （2.0 M NaOH, 90 min, 200 r/rain, pH 〉 13）. After the manganese was removed from the solution, the Zn（OH）4^2- was precipitated as zinc sulfate in the presence of sulfuric acid. The results indicated that this process could be effective in recovering manganese and zinc from alkaline batteries.

关键词： waste recycling alkaline batteries manganese zinc recovery

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SLANT SUBMANIFOLDS OF A RIEMANNIAN PRODUCT MANIFOLD

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Acta Mathematica Scientia 2010年第1期30卷 215-224页

作者： mehmet Ateken Department of Mathematics Faculty of Arts and SciencesGaziosmanpasa University

In this article, the geometry of the slant submanifolds of a Riemannian product manifold is studied. Some necessary and sufficient conditions on slant, bi-slant and semi-slant submanifolds are given. We research fundamental properties of the distributions which are involved in definitions of semi- and bi-slant submanifolds in a Riemannian product manifold.

关键词： slant distribution slant submanifold semi-slant and bi-slant submanifold

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