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One-year experience in the retinopathy of prematurity: frequency and risk factors, short-term results and follow-up

International Journal of Ophthalmology(English edition) 2011年第6期4卷 634-640页

作者： Sariaydin mehmet Atlihan Fusun Calkavur Sebnem Olukman ozgur Ercan Gulten Ozturk Arif Taylan Kaya Kilic Fatma Gokaslan Filiz Altinyaprak Derya Malatyali Rana Department of Neonatology Trabzon Medical Faculty Department of Neonatology Dr. Behet Uz Children's Hospital Department of Ophthalmology Dr. Behet Uz Children's Hospital

· AIM: As a result of the increase in premature births and the advances in neonatal intensive care, retinopathy of prematurity (ROP) remains one of the most important causes of childhood blindness worldwide. The main factors in the development of ROP are gestational age, birth weight and oxygen therapy. ROP continues to gain importance due to the increasing survival rates of more immature babies. · METHODS: Between January 2007 and October 2008, 203 premature infants treated at the Neonatal Intensive Care Unit (NNICU) were prospectively enrolled and the relationship between known risk factors and the occurance of ROP was studied. · RESULTS: ROP in various stages developed in 86 cases (42.4%). Statistically significant correlations were found between the development of ROP and birth weight (P < 0.0001) gestational age (P <0.0001), oxygen treatment and its duration (P <0.0001 and P =0.002), mechanical ventilation (MV) and its duration (P =0,0001 and P =0.0001), apnea(P = 0.001), intraventricular hemorrhage (IVH) (P =0.046), sepsis (P =0.0001), use of erythropoietin (EPO) (P =0.003), the number of blood transfusions and frequency (P =0.0001 and P =0.0001), surfactant application (P =0.0001), the presence of patent ductus arteriosus (PDA) (P =0.001) or bronchopu- lmonary dysplasia (BPD) (P =0.0001). No significant correlations were found between the occurance of ROP and maternal pre-eclampsia (P =0.293), multiple pregnancy (P = 0.218), or hyperbilirubinemia (P =0.494). Severity of ROP was related significantly with birth weight (P =0.0001), but no significant correlation between severity of ROP and gestational age was present. · CONCLUSION: Early description and reduction of the risk factors related with the occurance of ROP with the help of routine screening programs may warrant the prevention of visual loss, however early ophthalmic diagnosis and treatment are still mandatory to provide better visual rehabilitation. ·

关键词： prematurity retinopathy risk factors gestational age birth weight oxygen therapy

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Comparison of Biopsy Results and Imaging Methods,in the Diagnosis of Breast Cancer

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Surgical Science 2012年第9期3卷 445-451页

作者： mehmet Ali Eryilmaz ozgur Oner Ahmet Okus Omer Karahan Said Bodur Serden Ay Seher Civcik General Surgery Clinic Konya Training and Research HospitalKonyaTurkey Radyology Clinic Konya Training and Research HospitalKonyaTurkey Department of Public Health Meram Faculty of MedicineSelcuk UniversityKonyaTurkey Konya Early Diagnosis of Cancer-Screening and Education Center Kanser Erken Teshis-Tarama ve Egitim Merkezi(KETEM)KonyaTurkey

Purpose: In this study, we aimed at comparing the sensitivity and selectivity rates of Ultrasonography (USG), Mamography (MG) and Magnetic Resonance (MR), based on the biopsy results of breast mass lesions. Materials and methods: Between January 2009 and December 2010 in Konya Training and Research Hospital the biopsy results and reports of imaging tecniques such as USG, MG and MR, were obtained from the hospital automation. The sensitivity and selectivity of the USG, MG and MR were calculated. Results: The avarage age of the 112 patients included in this study is 49 ± 10 (23 - 71). 27 (24%) of the patients were found to have breast cancer after the histopathologic examination. USG was used with the 95 (94%) of the patients and 17 (18%) of the patients were diagnosed to have cancer. MG was used with the 75 (67%) of the patients and 15 (20%) of the patients were diagnosed to have cancer, and MR was used with the 112 (100%) of the patients and 25 (22%) of the patients were diagnosed to have cancer. In the pathologic diagnosis of cancer, the sensitivity of USG was found 85%, the sensitivity of MG was found 89%, and the sensitivity of MR was found 92%. The selectivity of these tecniques were 58%, 87% and 57% respectively. Conclusion: MR and MG have similar sensitivity rates in the diagnosis of breast cancer. Breast MR is an appropriate imaging tecnique that can be used in suitable indications in addition to USG and MG.

关键词： Breast Cancer Magnetic Resonance Mamography Ultrasonography

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Machine learning approach to drivers of bank lending:evidence from an emerging economy

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Financial Innovation 2021年第1期7卷 424-452页

作者： Onder ozgur Erdal Tanas Karagol Fatih Cemil Ozbugday Department of Economics Faculty of Political SciencesAnkara Yıldırım Beyazıt UniversityEsenboğa CampusCubukAnkaraTurkey

The study analyzes the performance of bank-specific characteristics,macroeconomic indicators,and global factors to predict the bank lending in Turkey for the period 2002Q4–*** objective of this study is first,to clarify the possible nonlinear and nonparametric relationships between outstanding bank loans and bank-specific,macroeconomic,and global ***,it aims to propose various machine learning algorithms that determine drivers of bank lending and benefits from the advantages of these *** empirical findings indicate favorable evidence that the drivers of bank lending exhibit some ***,partial dependence plots depict that numerous bank-specific characteristics and macroeconomic indicators tend to be important variables that influence bank lending *** study’s findings have some policy implications for bank managers,regulatory authorities,and policymakers.

关键词： Bank lending Machine learning techniques Decision trees Turkey

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Plasma Concentrations of Some Trace Element and Heavy Metals in Patients with Metastatic Colon Cancer

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Journal of Cancer Therapy 2013年第6期4卷 1085-1090页

作者： ozgur Emre Halit Demir Erkan Dogan Ramazan Esen Tugba Gur Canan Demir Edip Gonullu Nedim Turan mehmet Fatih Ozbay Division of Biochemistry Department of ChemistryScience FacultyYuzuncu Yil UniversityVanTurkey Department of Medical Oncology Medical FacultyYuzuncu Yil UniversityVanTurkey Department of Hematology Medical FacultyYuzuncu Yil UniversityVanTurkey Division of Biochemistry Health FacultyYuzuncu Yil UniversityVanTurkey Department of Biostatics Faculty of MedicineYuzuncu Yil UniversityVanTurkey Department of Anesthesiology and Reanimation Regional Training and Research Hospital of VanVanTurkey Department of Medical Oncology Faculty of MedicineGazi UniversityAnkaraTurkey Department of Internal Medicine Regional Training and Research Hospital of VanVanTurkey

Purpose: It is well known that trace elements and heavy metals play a significant role in human health and disease. These elements play an important role in different metabolic pathways of cells and tissues. Trace element deficiency or excess is implicated in the development or progression of some cancers. We present a study which investigates serum/ plasma levels of trace-heavy elements in metastatic colon cancer patients and healthy subjects. Methods: Blood samples were collected from 29 healthy subjects and 40 patients with metastatic colon cancer in Oncology Department of Medical School of Yuzuncu Yil University. In both groups, the serum levels of copper (Cu), magnesium (Mg), lead (Pb), chromium (Cr), zinc (Zn) selenium (Se), manganese (Mn), and cadmium (Cd) were determined. Results: Higher levels of Cu, Mg, Pb, Cr, Zn, Mn and Cd were seen in patients with metastatic colon cancer compared to healthy subjects and these findings were statistically significant (p 0.05). Se levels were noted to be lower in patients with colon cancer in comparison to healthy subjects and this finding was also statistically significant (p 0.05). Conclusions: According to our findings there was significant diffence in trace elements and heavy metals levels between healthy subjects and metastatic colon cancer patients. Therefore heavy metal and trace elements may have prognostic significance in complex disorders including colon cancer. However, further comprehensive studies are needed in order to advance our understanding of the relationship between heavy metal and trace elements and their role in cancers.

关键词： Colon Cancer Trace Element Heavy Metal Essential Element

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Diffusion-weighted and diffusion-tensor imaging of normal and diseased uterus

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World Journal of Radiology 2015年第7期7卷 149-156页

作者： Duygu Kara Bozkurt Murat Bozkurt mehmet Ali Nazli Ilhan Nahit Mutlu ozgur Kilickesmez Depatment of Radiology School of Medicine Kafkas University Depatment of Obstetrics and Gynecology School of Medicine Kafkas University Department of Diagnostic and Interventional Radiology Istanbul Training and Research Hospital

Owing to technical advances and improvement of the software, diffusion weighted imaging and diffusion tensor imaging(DWI and DTI) greatly improved the diagnostic value of magnetic resonance imaging(MRI) of the pelvic region. These imaging sequences can exhibit important tissue contrast on the basis of random diffusion(Brownian motion) of water molecules in tissues. Quantitative measurements can be done with DWI and DTI by apparent diffusion coefficient(ADC) and fractional anisotropy(FA) values respectively. ADC and FA values may be changed by various physiological and pathological conditions providing additional information to conventional MRI. The quantitative DWI assists significantly in the differentiation of benign and malignant lesions. It can demonstrate the microstructural architecture and celluler density of the normal and diseased uterine zones. On the other hand, DWI and DTI are useful for monitoring the treatment outcome of the uterine lesions. In this review, we discussed advantages of DWI and DTI of the normal and diseased uterus.

关键词： Magnetic resonance imaging Diffusion weighted imaging Diffusion tensor imaging Uterus

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