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国际眼科杂志 2013年第10期13卷 1950-1952页

作者： Muhsin Eraslan 0zlem Yenice Haluk Kazokoglu Dilek Goga yavuz Eren Cerman Hande Celiker 马尔马拉大学医学院眼科土耳其伊斯坦布尔34780 马尔马拉大学医学院内科土耳其伊斯坦布尔34780

目的:探讨血清唾液酸和糖尿病性视网膜病变几个阶段之间潜在的关联。方法:1型糖尿病视网膜不同程度病变组40例。对照组30例,对其血清唾液酸水平进行研究。结果:结果显示,研究组与对照组相比有较高的血清唾液酸浓度(95.95±9.5 vs 45.05... 详细信息

目的:探讨血清唾液酸和糖尿病性视网膜病变几个阶段之间潜在的关联。方法:1型糖尿病视网膜不同程度病变组40例。对照组30例,对其血清唾液酸水平进行研究。结果:结果显示,研究组与对照组相比有较高的血清唾液酸浓度(95.95±9.5 vs 45.05±19.91mmoL/L,P=0.0001)。我们也观察到糖尿病性视网膜病变的水平逐步上升,其浓度升高(P<0.05),但相关性较弱。血清唾液酸浓度与血糖浓度呈正相关(r=0.67,P=0.0001)。结论:血清唾液酸浓度的增加与视网膜病变阶段有关。这对确定1型糖尿病患者视网膜病变的程度有帮助。但是,仍然需要更详细的研究,以得到更精确的结论。

关键词：糖尿病糖尿病性视网膜病变血清唾液酸糖化血红蛋白

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少汗型外胚层发育不良：个案报道

中国口腔医学继续教育杂志 2008年第3期11卷 44-48页

作者： Lzzet yavuz DDS 吴青（译）张丁（审）不详北京协和医院口腔科正畸科北京东城区东单帅府园1号100730

外胚层发育不良症是一大类临床表现复杂的疾病，包括超过170余种临床情况。均由外胚层发育受损所导致，其特征为至少以下一种组织的原发性发育缺陷：指甲，头发，汗腺或牙齿。外胚层发育不良在病人幼年时即可影响其情感发育。此例个案... 详细信息

外胚层发育不良症是一大类临床表现复杂的疾病，包括超过170余种临床情况。均由外胚层发育受损所导致，其特征为至少以下一种组织的原发性发育缺陷：指甲，头发，汗腺或牙齿。外胚层发育不良在病人幼年时即可影响其情感发育。此例个案报道概述了一个7岁即诊断为少汗型外胚层发育不良的女孩在9岁时通过功能和外貌的修复，以期改善其社交行为的可行方法。

关键词：外胚层发育不良固定修复牙齿发育不良

EFFECT ON HIGH-CONTRAST DISRIMINATED-TARGET CENTRAL FIELDS OF SHORT TERM INVTTAVITREAL AVASTIN MONOTHERAPY FOR CNVM DUE TO AMD

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EFFECT ON HIGH-CONTRAST DISRIMINATED-TARGET CENTRAL FIELDS O...

Outcome and prognostic factors in 110 consecutive patients with primary uterine leiomyosarcoma:A Rare Cancer Network study

第十八届国际眼科研究大会

作者： Yaprak Banu.Unver Stephen H.Sinclair Gulderen.yavuz Peter.Presti Beyoglu Eye Traning and Research Hospital IstanbulTurkey

＜正＞Purpose:Central visual field testing with discriminated targets（Functional Acuity Analyzer,Vimetrics,Media,Pa）appears to offer significant *** pilot study compared ETDRS acuity with parameters derived from FAA...

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Chinese Journal of Cancer Research 2017年第6期29卷 521-532页

作者： Alessandra Franzetti Pellanda Berardino De Bari Elisabeth Deniaud-Alexandre MarcoKrengli Paul Van Houtte Antonella Riehetti Salvador Villa Hadassah Goldberg EwaSzutowiez-Zielifiska Michel Bolla Heidi Rutten Marc Van Eijkeren Philip Poortmans Guido Henke yavuz Anaeak Steve Chan Christine Landmann Carine Kirkove LueianoScandolaro Jacques Bernier Rene-Olivier Mirimanof Mahmut Ozsahin Centre Hospitalier Universitaire Vaudois(CHUV) 1011 LausanneSwitzerland Clinica Luganese Moncucco 6903 LuganoSwitzerland Centre Hospitalier R6gional Universitaire"Jean Minjoz" INSERMUMR109825030 BesangonFrance Hopital Tenon 75970 ParisFrance Centre Hospitalier Departemental 85925 VendeeFrance degli Studi del Piemonte Orientale e Ospedale Maggiore della Carifi 28100 NovaraItaly University Institut Jules Bordet 1000 BrusselsBelgium 8Ospedale di Circolo 21100 VareseItaly Ospedale di Circolo 21100 VareseItalyt Istituto Oncologico della Svizzera Italiana EOC6500 BellinzonaSwitzerland Catalan Institute of Oncology Universitat Autbnoma de Barcelona08916 Barcelona 08916Spain Rambam Medical Center 31096 HaifaIsrael Medical University 80210 GdanskPoland Hopital Michallon BP21738043Grenoble cedex 09France Radboud University Medical Center 6525 NijmegenThe Netherlands Ghent University Hospital 9000 GentBelgium Institute Verbeeten 90120 TilburgThe Netherlands Kantonsspital St.Gallen 9007St.GallenSwitzerland Karadeniz Technical University 61080 TrabzonTurkey Nottingham University Hospital NHS trustNG5 1PB NottinghamUnited Kingdom Kantonsspital Basel 4031 BaselSwitzerland UCL St.Luc 1200 BrusselsBelgium presidio Ospedaliero Sant'Anna 22100 ComoItaly Ospedale San Giovanni 6500 BellinzonaSwitzerland Clinique de Genolier Genolier1272 Switzerland Department of Radiation Oncology Centre Hospitalier Universitaire Vaudois(CHUV)University of LausanneSwitzerland

Objective： Primary uterine leiomyosarcomas （ULMS） are rare, and the optimal treatment is controversial. We aimed to assess the outcome and prognostic factors in a multicenter population of women treated for primary ULMS. Methods： We retrospectively collected data of 110 women treated in 19 institutions of the Rare Cancer Network （RCN）. Inclusion criteria consisted of a pathology report confirming the diagnosis of ULMS, aged 18-80 years, complete International Federation of Gynecology and Obstetrics （FIGO） stage information, complete information on treatment, and a minimum follow-up of 6 months. Local control （LC） and locoregional control （LRC）, overall survival （OS） and disease-free survival （DFS） rates were computed using the Kaplan-Meier method. Univariate analysis was implemented using the log rank test, and multivariate analysis using the Cox model. Results： All patients underwent surgery. Seventy-five patients （68%） received adjuvant radiotherapy （RT）, including brachytherapy in 18 （I 6%）. Seventeen patients （15 %） received adjuvant chemotherapy. Median follow-up was 58 （range, 6-240） months. Five-year OS and DFS rates were 50% and 34%, and LC and LRC rates were 88% and 72%, respectively. On multivariate analysis, independent favorable prognostic factors were younger age, FIGO stage I, small tumor size, previous uterine disease, and no vascular invasion for OS and DFS. FIGO stage was the only favorable factor influencing LRC. Adjuvant local or systemic treatments did not improve the outcomes. Eight patients treated with RT presented a grade 3 acute toxicity, and only one patient with grade 3 late toxicity. Conclusions： In this large population of primary ULMS patients, we found good results in terms of LC and LRC. Nevertheless, OS remains poor, mainly due to the occurrence of distant metastases. An early diagnosis seemed to improve the prognosis of the patients. Adjuvant local or systemic treatments, or more aggressive surgical procedures such as the Wertheim p

关键词： Uterine leiomyosarcoma prognostic factors radiotherapy overall survival local control

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政策制定中交通弱势群体受抑制需求分析方法

城市交通 2010年第3期8卷 79-94页

作者： yavuz Duvarcia Shoshi Mizokami 蒋中铭朱明伊兹密尔理工大学区域与城市规划系熊本大学土木与环境工程系清华大学交通研究所北京100084 克莱德贝尔格曼华通物料输送有限公司北京100035

在交通弱势群体受抑制需求可被计算、并将其加入现有出行需求的前提下,提出一种预估交通供需的方法。该方法的潜在假设是交通弱势群体的出行条件和普通群体相同,即所谓的受抑制需求"全部释放"。在利用"四阶段"法为交通弱势群体建模的过... 详细信息

在交通弱势群体受抑制需求可被计算、并将其加入现有出行需求的前提下,提出一种预估交通供需的方法。该方法的潜在假设是交通弱势群体的出行条件和普通群体相同,即所谓的受抑制需求"全部释放"。在利用"四阶段"法为交通弱势群体建模的过程中,分析了交通弱势群体的受抑制需求及其与普通群体间的平等问题,同时详尽阐述了最易受伤害的交通弱势群体(如老年人和残疾人)的特殊需求,并确定其在各方面面临的困难。最后,利用软件模拟分析得出的结论是:针对交通弱势群体全部释放的受抑制需求(出行总量增加5%),政策制定者须为面临一定的财政负担做好准备,同时做好协调工作,达到既减少运营成本又满足交通弱势群体出行需求的目标。

关键词：交通规划受抑制出行需求交通弱势群体残疾人和老年人

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谈摩托车的排放控制

摩托车技术 2004年第11期 98-99页

作者： Dr.Bulent yavuz 周靖康徐江安格集团安格亚太(中国)有限公司安格环保技术(上海)有限公司

中国摩托车工业曾在20世纪90年代显著增长,从1992年的摩托车需求量200万辆增长到2004年的1400万辆,摩托车的生产量已经超过了世界产量的一半.以前这些车辆在设计阶段不会去有意识地控制尾气排放量,这从客观上加剧了环境的污染.从2005年... 详细信息

中国摩托车工业曾在20世纪90年代显著增长,从1992年的摩托车需求量200万辆增长到2004年的1400万辆,摩托车的生产量已经超过了世界产量的一半.以前这些车辆在设计阶段不会去有意识地控制尾气排放量,这从客观上加剧了环境的污染.从2005年开始,中国摩托车生产厂家生产的车辆要实施欧Ⅱ排放标准.这项规定的实施充分体现了中国政府对改善人民生活质量的愿望.

关键词：中国摩托车生产厂摩托车工业人民生活质量生产量厂家需求量车辆欧Ⅱ排放标准排放控制

Fundamental Open Questions on Engineering of “Super” Hydrogen Sorption in Graphite Nanofibers: Relevance for Clean Energy Applications

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American Journal of Analytical Chemistry 2014年第16期5卷 1151-1165页

作者： Yury S. Nechaev Alp Yürüm Adem Tekin Nilgün Karatepe yavuz Yuda Yürüm T. Nejat Veziroglu Bardin Institute for Ferrous Metallurgy Moscow Russia Nanotechnology Research and Application Center Sabanci University Istanbul Turkey Informatics Institute Istanbul Technical University Istanbul Turkey Energy Institute Istanbul Technical University Istanbul Turkey Faculty of Engineering and Natural Sciences Sabanci University Istanbul Turkey International Association for Hydrogen Energy Miami USA

Herein, some fundamental open questions on engineering of “super” hydrogen sorption (storage) in carbonaceous nanomaterials are considered, namely: 1) on thermodynamic stability and related characteristics of some hydrogenated graphene layers nanostructures: relevance to the hydrogen storage problem;2) determination of thermodynamic characteristics of graphene hydrides;3) a treatment and interpretation of some recent STM, STS, HREELS/LEED, PES, ARPS and Raman spectroscopy data on hydrogensorbtion with epitaxial graphenes;4) on the physics of intercalation of hydrogen into surface graphene-like nanoblisters in pyrolytic graphite and epitaxial graphenes;5) on the physics of the elastic and plastic deformation of graphene walls in hydrogenated graphite nanofibers;6) on the physics of engineering of “super” hydrogen sorption (storage) in carbonaceous nanomaterials, in the light of analysis of the Rodriguez-Baker extraordinary data and some others. These fundamental open questions may be solved within several years.

关键词： Hydrogen “Super” Sorption (Storage) Graphenes Carbon Nanotubes Graphite Nanofibers A Breakthrough Hydrogen Storage Nanotecnology Clean Energy Applications

依靠创新降低成本——自动化的颗粒检查图像技术降低了造粒的生产成本

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流程工业 2014年第10期 58-59页

作者： Maik Ritter Thomas Waldleben yavuz Baykara Gunter Feddern Geistlich Pharma 公司 NNE PharmaplanSA公司

新的设备技术结合现代化的图像处理技术实现了造粒生产过程中的两大目标，即降低生产成本，及减轻操作者的劳动强度。

关键词：生产成本图像技术造粒自动化低成本检查颗粒创新

Oxidative stress in portal hypertension-induced rats with particular emphasis on nitric oxide and trace metals

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World Journal of Gastroenterology 2005年第23期11卷 3570-3573页

作者： Titiz Izzet Krand Osman Unal Ethem yavuz Nihat Kusaslan Ramazan Dogan Mustafa Uzun Hafize Kiziler Ali Riza Aydemir Birsen Genc Habibe Aydin Seval Simsek Gonul Department of Surgery Department of Biochemistry Department of Biophysics Department of Physiology

AIM: To investigate the oxidative-stress-related changes in rats with portal hypertension with particular emphasis on nitric oxide (NO) and trace metals. METHODS: Cirrhosis was induced by partial portal vein ligation (PVL) in Wistar rats. The lipid peroxidation marker (malondialdehyde, MDA), antioxidant defense enzymes including superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), and agents known to have antioxidant features including nitric oxide (NO), zinc (Zn), copper (Cu) were determined both in serum and in liver tissue at 4 wk after surgery in PVL and sham-operated rats. Portal pressure of all experimental animals was measured. MDA was detected by thiobarbituric acid reactivity *** activity was determined by inhibition of nitroblue tetrazolium reduction with xanthine/xanthine oxidase used asa superoxide generator. CAT activity was determined by the breakdown of hydrogen peroxide. GSH concentrations were measured by using metaphosphoric acid for protein precipitation and 5'-5'-dithio-bis-2-nitrobenzoic acid for color development. NO was detected by the Griess method after reduction of nitrate to nitrite with nitrate reductase, and the concentrations of Zn and Cu were measured by a Shimadzu 680 AA atomic absorption spectrometer. Histopathological confirmation was done under light microscope. Statistical analyses were done by Student's t-test, and significance of the difference was tested by the unpaired Mann-Whitney test. P＜0.05 was considered statistically ***: Histopathological studies confirmed PVL induced cirrhotic changes. There was a statistically significant difference in portal pressure between PVL and control groups (P＜0.001). The results showed significant increases in the levels of MDA and NO in both tissue and serum (P＜0.05 and P＜0.001, respectively in tissue; P＜0.001 for each in serum), and Zn only in tissue (P＜0.001)in rats with PVL compared with sham-operated rats. Besides, PVL rats exhibited reduced plasma and tis

关键词：肝门静脉高压氧化损伤小鼠动物实验一氧化氮