检索结果-南通市图书馆

Changes of total antioxidant capacity and total oxidant status of aqueous humor in diabetes patients and correlations with diabetic retinopathy

引用

International Journal of Ophthalmology(English edition) 2013年第4期6卷 531-536页

作者： Emrullah Beyazyildiz Ali Bülent ankaya Esra Ergan Mustafa Alparslan Anayol Yasemin zdamar Sevilay Sezer mehmet hakan tirhis Pelin Yilmazbas Faruk ztürk Department of Ophthalmology Gazi Mustafa Kemal State HospitalAnkara 06900Turkey Department of Ophthalmology Ulucanlar Eye Research and Training HospitalAnkara 06900Turkey Department of Ophthalmology Van Government HospitalVanAnkara 06900Turkey Department of Biochemistry Numune Research and Training HospitalAnkara 06900Turkey

AIM:To measure changes of total oxidant status(TOS)and total antioxidant capacity(TAC) of aqueous humor(AH) in diabetic retinopathy(DR) patients,and to determine if there were any differences in TOS and TAC of AH in diabetic patients without retinopathy compared with non-diabetic patients.·METHODS:One hundred and three eyes of 103patients who were enrolled for cataract surgery were included in this *** were grouped according to presence of diabetes and stage of *** to cataract surgery,0.1mL to 0.2mL of AH was aspirated and analyzed for TAC and TOS level using a colorimetric method.·RESULTS:TOS levels were highest among proliferative diabetic retinopathy(PDR) patients and lowest in patients with only *** were statistically significant between all groups(P <0.05).Whereas result between diabetic without retinopathy patients and non-proliferative diabetic retinopathy(NPDR) patients was not statistically significant(P =0.757).TAC levels were highest in patients with only cataract and lowest among PDR patients and results were statistically significant between all groups(P <0.05).·CONCLUSION:Aqueous humor TAC levels are low in diabetic patients and reduced further in DR patients,TOS levels are increased in diabetic patients and this is exacerbated in DR patients.

关键词： aqueous humor diabetic retinopathy total antioxidant capacity total oxidant status

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Reductive atmospheric acid leaching of spent alkaline batteries in H_2SO_4/Na_2SO_3 solutions

引用

International Journal of Minerals,Metallurgy and Materials 2015年第7期22卷 674-681页

作者： mehmet hakan Morcali Faculty of Chemical and Metallurgical Engineering Istanbul Technical University

This work studies the optimum reductive leaching process for manganese and zinc recovery from spent alkaline battery paste. The effects of reducing agents, acid concentration, pulp density, reaction temperature, and leaching time on the dissolution of manganese and zinc were investigated in detail. Manganese dissolution by reductive acidic media is an intermediate-controlled process with an activation energy of 12.28 kJ＇mo1-1. After being leached, manganese and zinc were selectively precipitated with sodium hydroxide. The zinc was entirely con- verted into zincate （Zn（OH）42-） ions and thus did not co-precipitate with manganese hydroxide during this treatment （2.0 M NaOH, 90 min, 200 r/rain, pH 〉 13）. After the manganese was removed from the solution, the Zn（OH）4^2- was precipitated as zinc sulfate in the presence of sulfuric acid. The results indicated that this process could be effective in recovering manganese and zinc from alkaline batteries.

关键词： waste recycling alkaline batteries manganese zinc recovery

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Sequence analysis of Turkish field strains of bovine torovirus shows unique amino acid changes in the partial M gene

引用

Asian Pacific Journal of Tropical Biomedicine 2019年第3期9卷 129-134页

作者： hakan Aydin mehmet Ozkan Timurkan Gulizar Acar Kirmizi Department of Virology Faculty of Veterinary University of Ataturk

Objective: To investigate the presence, prevalence and phylogenetic classification of bovine torovirus(BToV). Methods: Stool samples from 72 calves, which were negative for primary gastroenteritis agents, were examined with the nested PCR method by using BToV M genespecific primers. Results: BToV was detected in 12(16.7%) out of 72 samples. Phylogenetic analysis was performed using nucleotide and amino acid sequences. In the phylogenetic tree, European, American, Far East and Turkish strains were found to be divided into different branches. Interestingly, it was observed that Turkish strains were divided into two subgroups. Considering the amino acid sequences of these strains having differences at nucleotide level, the change at the 3rd amino acid of the partial M gene in Turkish strains has made Turkish strains different from all other strains. Similarly, the differences were observed in the 18th, 20th, 63rd and 93rd amino acids of the partial M gene only in Turkish field strains. Conclusions: This study revealed that Turkish strains of BToV constitute a separate phylogenetic group and can be divided into two subgroups. In addition, BToV was found to be a common pathogen causing diarrhea in calves in Turkey, and it is a necessity to consider BToV in cases of diarrhea with unknown cause.

关键词： Calf Diarrhea Torovirus Turkey

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comparison of purification processes of natural gas obtained from three different regions in the world

引用

Journal of Natural Gas Chemistry 2012年第1期21卷 61-68页

作者： Tansel Koyun mehmet Kunduz hakan F. Oztop Ibrahim Ucgul Department of Mechanical Engineering Suleyman Demirel University Department of Mechanical Engineering Technology Faculty Fιrat University Deparment of Mechanical Engineering College of Engineering King Saud University Department of Textile Engineering Suleyman Demirel University

Natural gases obtained from different regions in the world as Scholen-Germany, Saudi Arabia and Iran were purified with a package code and the obtained results were compared in this study. For purification process, both natural gases flowing in a vertical pipe and monoethanolamine （MEA） flowing as a film from the internal surface of a pipe were examined together. Both fluids were flown in a vertical and laminar regime. Binary diffusion coefficients, Schmidt numbers （Sc） and dynamical viscosities were calculated individually for three types of natural gases. It is demonstrated that the chemical absorption method by MEA process is the most appropriate method at high DamkOhler （Da） numbers particularly for natural gases containing high concentrations of CO2 and H2S.

关键词： natural gas purification monoethanolamine (MEA)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Achillea biebersteinii extracts suppress angiogenesis and enhance sensitivity to 5-fluorouracil of human colon cancer cells via the PTEN/AKT/mTOR pathway in vitro

引用

Asian Pacific Journal of Tropical Biomedicine 2020年第11期10卷 505-515页

作者： mehmet Kadir Erdoğan Can Ali Ağca hakan Aşkın Department of Biology Faculty of Arts and SciencesBingol University12000BingolTurkey Department of Molecular Biology and Genetics Faculty of Arts and SciencesBingol University12000BingolTurkey Department of Molecular Biology and Genetics Faculty of SciencesAtaturk University25000ErzurumTurkey

Objective:To investigate the antiproliferative,anti-angiogenic,and apoptotic effects of extracts of Achillea biebersteinii(ABE)and combined treatments of ABE with 5-fluorouracil(5-FU)on HT-29 ***:The effects of ABE,5-FU,and combined treatments on the viability of HT-29 cells were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide *** analysis was used to determine synergism between ABE and *** apoptotic and anti-angiogenic effects were determined by cell death detection and human vascular endothelial growth factor ELISA method,*** and translational expressions of p53,Bax,Bcl-2,p38 MAPK,Akt,PTEN,and m TOR were also evaluated by real-time PCR and Western blotting ***:ABE decreased the viability of HT-29 cells in a dosedependent *** treatment of hexane,chloroform,and methanol extracts of Achillea biebersteinii with 5-FU at IC50 doses decreased the cell viability to 26.0%,19.1%,and 14.9%,respectively(P<0.001).Furthermore,ABE treatment alone and combination with 5-FU,induced apoptosis,significantly downregulated m TOR,Akt,Bcl-2 expression,upregulated p53,Bax,PTEN,p38 MAPK expression,and exhibited anti-angiogenetic ***:Our findings indicate that ABE shows synergism with 5-FU and inhibits the proliferation of HT-29 cells by inducing apoptosis and suppressing angiogenesis,which may provide biological evidence for further use of ABE in the treatment of colorectal cancer.

关键词： angiogenesis doses colon

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Clinical efficacy and drug resistance of anti-epidermal growth factor receptor therapy in colorectal cancer

引用

World Journal of Gastrointestinal Oncology 2016年第1期8卷 1-7页

作者： hakan kocoglu fatih mehmet velibeyoglu mustafa karaca deniz tural department of medical oncology bakirkoy education and research hospital34900 IstanbulTurkey department of medical oncology gazi university faculty of medicine06500 AnkaraTurkey

Colorectal cancer(CRC) ranked third in cancer related death and its incidence has been increasing worldwide. In recent decades important therapeutic advances have been developed in treatment of metastatic CRC(mCRC), such as monoclonal antibodies against epidermal growth factor receptor(anti-EGFR), which provided additional clinical benefits in mCRC. However, anti-EGFR therapies have limited usage due to approximately 95% of patients with KRAS mutated mCRC do not response to anti-EGFR treatment. Thus, KRAS mutation is predictive of nonresponse to anti-EGFR therapies but it alone is not a sufficient basis to decide who should not be received such therapies because; approximately fifty percent(40%-60%) of CRC patients with wild-type KRAS mutation also have poor response to anti-EGFR based treatment. This fact leads us to suspect that there must be other molecular determinants of response to anti-EGFR therapies which have not been identified yet. Current article summarizes the clinical efficacy of anti-EGFR therapies and also evaluates its resistance mechanisms.

关键词： Colorectal cancer Epidermal growth factorreceptor KRAS mutation Anti-epidermal growth factorreceptor antibody Drug resistance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Efficient Plant Regeneration with Arabinogalactan-Proteins on Various Ploidy Levels of Cereals

引用

Journal of Integrative Agriculture 2013年第3期12卷 420-425页

作者： Yasemin Coskun Ragbet Ezgi Duran Cigdem Savaskan Tunhan Demirci mehmet Tolgahan hakan Department of Biology Faculty of Arts and Sciences Suleyman Demirel University

To determine the most effective dose of arabinogalactan-protein （AGP） in regeneration medium, mature embryos of genotypes in three different ploidy levels （Triticum aestivum L. cv. Ikizce-96, Triticum durum Desf. cv. Mirzabey and Hordeum vulgare L. cv. Tokak） were used to establish an efficient plant regeneration system for cereals. Percentage of callus production, capacity of regeneration were calculated, and also culture effect, root, stem, and total plant length of regenerant plants were observed in six different regeneration media （MS control, MS＋2, 5, 7, 10, 12 mg L-1 AGP） in these three different genotypes. According to the results, the highest amount of callus production was found in Ikizce-96 as 93.75% using 5 mg L-1 dicamba and 1 mg L-1 kinetin in induction medium. However, the most improved callus was observed in diploid barley Tokak as 179.95 mg in weight and 6.18 mm in diameter, respectively. The highest regeneration capacity was observed in the dose of 5 mg L-1 AGP in MS of all the genotypes and hexaploid wheat Ikizce-96 gave the best results with the highest regeneration capacity and culture effects （94.86 and 92.5%） in the same dose of AGE These results indicated that effective dose of AGP in regeneration medium increase plant regeneration in calli derived from cereal mature embryos.

关键词： arabinogalactan-protein (AGP) cereal mature embryo plant regeneration tissue culture

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Endophthalmitis caused by Bacteroides fragilis after pars plana vitrectomy and treatment approach

引用

Asian Pacific Journal of Tropical Medicine 2022年第1期15卷 44-46页

作者： hakan Yildirim mehmet Balbaba Turgut Yilmaz Zülal Asci Toraman Faculty of Medicine Department of OphthalmologyFirat UniversityElazig 23119Turkey Medical Park Hospital ElazigTurkey Faculty of Medicine Department of MicrobiologyFirat UniversityElazig 23119Turkey

Rationale:Endophthalmitis is an uncommon but serious ocular infection often resulting in probable visual *** fragilis is a rare cause of *** concerns:A 46-year-old male patient complained of eye pain and low vision after pars plana ***:Bacteroides fragilis endophthalmitis after pars plana vitrectomy was ***:Pars plana vitrectomy and silicone oil implantation were ***:Early treatment and choice of tamponade in endophthalmitis after pars plana vitrectomy may possibly prevent evisceration and progression of ***:Bacteroides fragilis can be seen in cases of endophthalmitis after pars plana vitrectomy.

关键词： Bacteroides fragilis Endophthalmitis Pars plana vitrectomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Protective effect of pomegranate juice on retinal oxidative stress in streptozotocin-induced diabetic rats

引用

International Journal of Ophthalmology(English edition) 2017年第11期10卷 1662-1668页

作者： Betul Tugcu Senay Asik Nacaroglu Asuman Gedikbasi mehmet Uhri Nur Acar hakan Ozdemir Department of Ophthalmology Faculty of Medicine Bezmialem University Istanbu134093 Turkey Department of Ophthalmology Bagcilar Training and Research Hospital Istanbu134200 Turkey Department of Biochemistry Bakirkoy Dr. Sadi Konuk Training and Research Hospital Istanbu134147 Turkey Department of Pathology Kanuni Sultan Suleyman Training and Research Hospital Istanbu134303 Turkey Department of Ophthalmology Acibadem University School of Medicine Istanbu134457 Turkey

AIM： To investigate the effect of pomegranate juice（PJ） intake on overall oxidation status in retinas of diabetic ***： Twenty-seven rats were divided into four groups as control（CO）, diabetic（DM）, control treated with PJ（CO-PJ）, and diabetic treated with PJ（DM-PJ）.The retina tissues were used to determine 8-hydroxy-2＇-deoxyguanosine（8 OHd G）, malondialdehyde（MDA）, reduced glutathione（GSH） levels, and the enzyme activities of superoxide dismutase（SOD） and glutathione peroxidase（GSH-Px）. RESULTS： The levels of 8 OHdG and MDA were significantly increased in the retina of DM group compared to CO group（P=0.001, P〈0.001 respectively）. Both 8 OHd G and MDA levels were decreased in PJ-DM group compared to DM group（P=0.004, P〈0.001 respectively）. The activities of antioxidant enzymes GSH, SOD, and GDH-Px were significantly decreased in the retina of DM group compared to CO group（P≤0.01）. GSH and GSH-Px activities were higher in PJ-DM group compared with DM group（P=0.010, P=0.042, respectively） but SOD activity was not statistically different（P=0.938）. CONCLUSION： PJ intake is found to be effective in decreasing oxidative end products, and in increasing the activities of antioxidant enzymes in diabetic retinas of rats, which suggests it may be effective against oxidative stress in diabetic retinas.

关键词： antioxidant enzymes diabetic retinopathy immunohistochemical staining oxidative stress pomegranate juice

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Better outcomes with desmopressin melt than enuretic alarm therapy in children with nocturnal enuresis during coronavirus disease 2019(COVID-19)

引用

Current Urology 2022年第2期16卷 70-73页

作者： Umut Unal hakan Anil mehmet Eflatun Deniz Ediz Vuruskan Adem Altunkol hakan Ercil Department of Urology Health Sciences UniversityAdana City Teaching and Research HospitalAdana01370Turkey Department of Urology Adana Seyhan State HospitalAdanaTurkey Department of Urology Kozan State HospitalAdanaTurkey

Objectives:This study aimed to investigate the effect of the coronavirus disease 2019(COVID-19)pandemic on the treatment of children with primary monosymptomatic nocturnal enuresis(MNE)with desmopressin melt versus an enuresis *** and methods:This study included 56 children with primary MNE who were taking desmopressin melt or using an *** anxiety levels were evaluated using the Social Anxiety Scale for *** both treatment methods,data from a 3-month bedwetting diary between the third and sixth months of the pre-pandemic treatment were compared with those assessed during the same period during the ***:Prior to the COVID-19 pandemic,the median 3-month mean frequency of MNE was 1(0-7.67)in children using desmopressin melt versus 1.33(0-6)in those using alarm treatment(p=0.095).During the COVID-19 pandemic period,the median monthly mean frequency of MNE was 1.33(0-7.33)in children using desmopressin melt versus 6(1.33-13)in those using alarm treatment(p<0.001).Conclusions:The COVID-19 pandemic and its accompanying psychological effects did not affect the treatment efficacy of desmopressin melt in children with primary MNE but did adversely affect that of enuresis alarms.

关键词： COVID-19 Desmopressin melt Enuresis alarm Nocturnal enuresis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：