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国际眼科杂志 2016年第1期16卷 19-23页

作者： Feride Aylin Kantarci Muhammed Nabi Kantarci mehmet gurkan tatar Emine Esra Karaca 法提赫大学医学院眼科土耳其伊斯坦布尔马尔泰佩34844 法医科学研究所司法行政部法医学系土耳其伊斯坦布尔Bahcelievler34196 索尔贡州立医院眼科土耳其约兹加特索尔贡66700

目的:调查眼睑皮肤松垂的位置和程度及是否伴随假性上睑下垂与年龄的关系。方法:选取113例眼睑皮肤松垂患者纳入本研究,记录患者的年龄,性别及体质指数。于第一眼位检测睑裂高度和睑缘至瞳孔反射点距离(MRD)。皮肤松垂的程度分为1级:皮... 详细信息

目的:调查眼睑皮肤松垂的位置和程度及是否伴随假性上睑下垂与年龄的关系。方法:选取113例眼睑皮肤松垂患者纳入本研究,记录患者的年龄,性别及体质指数。于第一眼位检测睑裂高度和睑缘至瞳孔反射点距离(MRD)。皮肤松垂的程度分为1级:皮肤松垂未及睑缘(至少距睑缘1 mm);2级:皮肤松垂达睑缘水平;3级:皮肤松垂越过睑缘前。结果:患者平均年龄为52.7±8.6(32~74)a。男36例(31.9%),女77例(68.1%)。平均体质指数为30.3±4.7(21.5~36.6)kg/m^2,平均睑裂高度为10.7+1.6(7~15)mm,平均MRD为3.8±1.2(1~5)mm。30例(26.5%)患者的皮肤松垂未及睑缘(1级)38例(33.6%)患者位于睑缘水平线(2级),而45例(39.8%)患者越过睑缘前(3级)。50例(44.2%)患者由于皮肤松垂引起假性上睑下垂。皮肤松垂程度在年龄方面的差异显著。皮肤松垂1级和2级患者的平均年龄(50.3±6.6,50.5±9.5岁)明显低于3级患者年龄(56.0±8.2岁)。假性上睑下垂患者(56.3±8.3岁)的平均年龄明显高于非假性上睑下垂患者(49.8±7.8岁)。对于皮肤松垂严重程度和假性上睑下垂患者体质指数无显著差别。结论:皮肤松垂严重程度和假性上睑下垂的发生率随年龄的增长而有所增加。

关键词：年龄上睑下垂眼睑皮肤松垂

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脉络膜厚度与体温日间变化的研究（英文）

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国际眼科杂志 2017年第6期17卷 1028-1032页

作者： mehmet gurkan tatar Feride Aylin Kantarci Bulent Gurler Hasim Uslu Hasan Goker Hatice Nur Colak Aydin Yildirim 法提赫大学医学院眼科土耳其伊斯坦布尔马尔泰佩34844

目的:通过深度增强成像光断层扫描(EDI-OCT)技术以探究体温如何影响脉络膜厚度。方法:前瞻性研究。通过EDI-OCT检测9∶00~17∶00中心凹(SF-CT),中心凹鼻侧500μm(N-CT)和中心凹颞侧500μm(T-CT)正常人(41例)的脉络膜厚度(CT)。使用非接... 详细信息

目的:通过深度增强成像光断层扫描(EDI-OCT)技术以探究体温如何影响脉络膜厚度。方法:前瞻性研究。通过EDI-OCT检测9∶00~17∶00中心凹(SF-CT),中心凹鼻侧500μm(N-CT)和中心凹颞侧500μm(T-CT)正常人(41例)的脉络膜厚度(CT)。使用非接触式红外测温仪逐时检测体温(BT),以评估CT和BT日间变化的相关性。结果:SF-CT值在9∶00和13∶00(P=0.021),9∶00和14∶00(P=0.012),9∶00和16∶00(P=0.048),及9∶00和17∶00(P=0.002)之间存在显著性差异。N-CT值在8h内(均P>0.05)无显著性变化,9∶00和13∶00(P=0.004)则存在明显差异。结论:CT与BT从9∶00~17∶00之间逐时变化无显著性差异。

关键词：体温脉络膜厚度日间变化

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Is there a connection between synthetic bone grafts and sisters chromatide exchange?

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Open Journal of Stomatology 2013年第8期3卷 447-451页

作者： Banu gurkan Koseoglu Amila Brkic mehmet Ali Erdem Sukru Ozturk Sukru Palanduz Kivanc Cefle Department of Oral and Maxillofacial Surgery School of DentistryIstanbul UniversityIstanbulTurkey Department of Oral Surgery School of DentistrySarajevo UniversitySarajevoBosnia and Herzegovina Division of Medical Genetics Department of Internal MedicineSchool of MedicineIstanbul UniversityIstanbulTurkey

Background: In oral and maxillofacial surgery, synthetic bone grafts are most widely used as bone substitutes, due to the limited sources of autologous bone. The aim of this study was to examine the influence of three different synthetic bone grafts (Cerasorb, Fortoss and Perioglass) on sisters chromatide exchanges (SCEs) in peripheral lymphocytes. Materials and Methods: Peripheral blood samples taken from 68 patients (45 females and 23 males), who underwent oral surgery procedures, such as apical resection, cyst enucleation or periodontal curretage, were obtained for SCE a day before and two months after the surgeries. A control group included 30 patients, while the study group was made of the patients who underwent bone grafting with Cerasorb? (11 patients), Fortoss? VITAL (10 patients) or Perioglass? (17 patients). Results: Comparing with the results of the study group before and after the treatment, it was concluded that the results were statistically significant (p = 0.001). In the Perioglass? subgroup, a greater statistical significance (p = 0.003) was noted, than that in either the Cerasorb? (p = 0.620) or Fortoss? (p = 0.210) subgroups, in which there was no statistical significance. Conclusions: Although further investigations may be necessary, our results suggest that the synthetic bone grafts might have an influence on SCE in peripheral lymphocytes.

关键词： Bone Graft Sisters Chromatide Exchange Genotoxic Bone Defect

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Cost of Treatment of Chronic Spontaneous Urticaria in Turkey

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Health 2016年第11期8卷 1098-1103页

作者： Mehtap tatar Ayşen Şentürk Gülpembe Ergin Oğuzhan Esin Tuna Cem Mat Emel Bülbül Başkan Ferda Artüz mehmet Ali Gürer Nilgün Atakan Serhat İnalöz Selin Sezen Çavuşoğlu Abdülkadir Keskinaslan İsmail Mete Şaylan Department of Health Care Management Faculty of Economics and Administrative Sciences Hacettepe University Ankara Turkey Polar Health Economics and Policy Consultancy Ankara Turkey Istanbul University Cerrahpasa Faculty of Medicine Istanbul Turkey Uludag University Faculty of Medicine Bursa Turkey Ankara Numune Training and Research Hospital Ankara Turkey Gazi University Faculty of Medicine Ankara Turkey Hacettepe University Faculty of Medicine Ankara Turkey Gaziantep University Faculty of Medicine Gaziantep Turkey Novartis Suryapi & Akel is Merkezi istanbul Turkey

Chronic Spontaneous Urticaria (CSU) is a chronic disease with significant negative impact on quality of life of patients. The direct and indirect costs of the disease can be substantial both for the health care system and society. The aim of this research is to estimate the cost of mild, moderate and severe CSU in Turkey and to forecast the cost of the disease from the payer (Social Security Institution—SSI) perspective. Expert opinions with Delphi technique were used in order to determine the cost items and their frequency. A questionnaire was designed to outline resources used in the out-patient, inpatient and emergency care episodes and was answered by dermatologists followed by a consensus meeting. Unit costs were calculated from the price list of the SSI. The annual total cost of treating the disease to the SSI was estimated as 262,111,978TL (94,417,870€) comprising 0.06% of the total healthcare budget in 2013. Since there is limited information about the cost of CSU in Turkey, the methodology and results of this study are unique and very important.

关键词： Chronic Idiopathic Urticaria Chronic Spontaneous Urticaria Turkey Cost

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