检索结果-南通市图书馆

Elevated alanine aminotransferase activity is not associated with dyslipidemias,but related to insulin resistance and higher disease grades in non-diabetic non-alcoholic fatty liver disease

引用

Asian Pacific Journal of Tropical Biomedicine 2012年第9期2卷 702-706页

作者： mohammad Ebrahim Ghamar-Chehreh Mohsen Amini Hossein Khedmat Seyed Moayed Alavian Fatemeh Daraei Reza Mohtashami Reza hadi Bent-Al-Hoda Beyram saeed Taheri The internist Research Center Baqiyatallah Research Center for Gastroenterology and Liver Diseases Baqiyatallah University of Medical Sciences Dr.Taheri Medical Research Group

Objective:To explore demographic and metabolic factors associated with increased alanine aminotransferase(ALT)activity in non-diabetic non-alcoholic fatty liver disease(NAFLD)***:Overall 372 patients who consecutively attended to Gastroenterology Clinic of Baqiyatallah University of Medical Sciences,Tehran,iran awere diagnosed as NAFLD entered into *** criteria were having diabetes mellitus and fasting blood glucose over126 mg/dL,active hepatitis B virus infection,having hepatitis C virus positive serology,and to be under corticosteroid *** levels were considered pathologically high when it was over30 iU/L for men and over 19 iU/L for ***:Bivariate analyses using t test and chisquare test showed that patients with pathologically augmented ALT levels had significantly higher NAFLD grades in their ultrasonographic evaluations(P=0.003).Moreover,these patients represented significantly higher homeostatic model assessment levels(P=0.003),levels of serum insulin(P=0.002),fasting blood glucose(Pic acid(P=0.02).The prevalence of insulin resistance was also higher in patients with increased serum ALT *** logistic regression models showed that ultrasonographic grading of NAFLD(P=0.027)and insulin resistance(P=0.013)were the only variables significantly associated with abnormal ALT ***:This study shows that the associations of increased ALT serum levels in NAFLD patients are different from what are supposed *** excluding diabetic patients from our population,we find that increased ALT levels are not associated with dyslipidemias but are independently associated with insulin resistance and NAFLD grading on ultrasonographic *** studies are needed to confirm our results.

关键词： Alanine aminotransferase Non-alcoholic fatty liver disease insulin resistance Fasting blood glucose Ultrasonographic evaluation Diabetes mellitus Metabolic factor Serum insulin Dyslipidemia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular study of HCV detection,genotypes and their routes of transmission in North West Frontier Province,Pakistan

引用

Asian Pacific Journal of Tropical Biomedicine 2012年第7期2卷 532-536页

作者： Asher Zaman Safi Yasir Waheed Joharia Sadat Solat-Ul-islam Sadia Salahuddin Umar saeed Muhammad Ashraf Atta-ur-Rahman School of Applied Biosciences(ASAR) National University of Science and Technology(NUST) Lady Reading Hospital(L.R.H)Peshawar

Objective:To determine hepatitis C virus(HCV) genotypes and explore the associated risk factors in chronic HCY ***:A total of 116 patients with chronic hepatitis C were subjected to polymerase chain reaction(PCR) based detection out of which 112 chronic HCV patients[53 male(47.32%),59 female(52.68%);mean age(43.76±16.40) years;mean Bmi(23.8± 3.9)kg]were enrolled in this *** frequency of 6 HCV genotypes and associated risk factors were evaluated from five districts of North West Frontier Province(NWFP).Results:Genotype 3was the most prevalent in 73 samples(65.17%) followed by genotype 1 in 24(21.42%) and genotype2 in 13(11.60%) ***3 had significantly high prevalence(P=0.0002).The results showed that 48(42.85%) samples were infected with HCV 3a:25(22.32%) with 3b;14(12.50%) with 1a;10(8.92%)with 1b;11(9.82%) with 2a;2(1.78%) with 2b;and 2 were *** distribution of HCV genotypes in ***,*** and Nowshehra districts was *** of unsterile equipment lor medication,barbers and previous history of hospitalization were the main risk factors for HCV ***:Cenotype 3a and 3b.1a.1b and 2a are the common genotypes in *** *** 6 can not be found in a single *** level of awareness about various modes ot transmission of HCV among the population is found to be verv low.

关键词： HCV Genotypes Subtype 3a Risk factors NWFP Transmission Molecular study PCR

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：