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Performance of generative pre-trained transformers (GPTs) in Certification Examination of the College of Family Physicians of Canada

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Family Medicine and Community Health 2024年第S1期12卷 12-19页

作者： mehdi Mousavi Shabnam Shafiee Jason M Harley Jackie Chi Kit Cheung Samira Abbasgholizadeh Rahimi Department of Family Medicine Faculty of MedicineUniversity of SaskatchewanNipawinSaskatchewanCanada Department of Family Medicine Saskatchewan Health AuthorityRiverside Health ComplexTurtlefordSaskatchewanCanada Department of Surgery Faculty of Medicine and Health SciencesMcGill UniversityMontrealQuebecCanada Research Institute of the McGill University Health Centre MontrealQuebecCanada Institute for Health Sciences Education Faculty of Medicine and Health SciencesMcGill UniversityMontrealQuebecCanada McGill University School of Computer Science MontrealQuebecCanada CIFAR AI Chair Mila-Quebec AI InstituteMontrealQuebecCanada Department of Family Medicine McGill UniversityMontrealQuebecCanada Mila Quebec AI-Institute MontrealQuebecCanada Faculty of Dentistry Medicine and Oral Health Sciences McGill UniversityMontrealQuebecCanada Lady Davis Institute for Medical Research Jewish General HospitalMontrealQuebecCanada

Introduction The application of large language models such as generative pre-trained transformers(GPTs)has been promising in medical education,and its performance has been tested for different medical *** study aims to assess the performance of GPTs in responding to a set of sample questions of short-answer management problems(SAMPs)from the certification exam of the College of Family Physicians of Canada(CFPC).Method Between August 8th and 25th,2023,we used GPT-3.5 and GPT-4 in five rounds to answer a sample of 77 SAMPs questions from the CFPC *** independent certified family physician reviewers scored AI-generated responses twice:first,according to the CFPC answer key(ie,CFPC score),and second,based on their knowledge and other references(ie,Reviews’score).An ordinal logistic generalised estimating equations(GEE)model was applied to analyse repeated measures across the five *** According to the CFPC answer key,607(73.6%)lines of answers by GPT-3.5 and 691(81%)by GPT-4 were deemed ***’s scoring suggested that about 84%of the lines of answers provided by GPT-3.5 and 93%of GPT-4 were *** GEE analysis confirmed that over five rounds,the likelihood of achieving a higher CFPC Score Percentage for GPT-4 was 2.31 times more than GPT-3.5(OR:2.31;95%CI:1.53 to 3.47;p<0.001).Similarly,the Reviewers’Score percentage for responses provided by GPT-4 over 5 rounds were 2.23 times more likely to exceed those of GPT-3.5(OR:2.23;95%CI:1.22 to 4.06;p=0.009).Running the GPTs after a one week interval,regeneration of the prompt or using or not using the prompt did not significantly change the CFPC score *** In our study,we used GPT-3.5 and GPT-4 to answer complex,open-ended sample questions of the CFPC exam and showed that more than 70%of the answers were accurate,and GPT-4 outperformed GPT-3.5 in responding to the *** language models such as GPTs seem promising for assisting candidates of the CFPC exam by pr

关键词： Canada prompt education

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Oxygen vacancy promoting artificial atom(RuPd)by d-orbital coupling for efficient water dissociation

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Nano Research 2024年第8期17卷 7045-7052页

作者： Ruofan Shen Yanyan Liu Shuling Liu Shuyan Guan Huanhuan Zhang Sehrish mehdi Saima Ashraf Ting-Hui Xiao Erjun Liang Jianchun Jiang Yongfeng Wang Baojun Li Laboratory of Zhongyuan Light School of PhysicsZhengzhou UniversityZhengzhou 450001China Key Laboratory of Materials Physics Ministry of EducationSchool of PhysicsZhengzhou UniversityZhengzhou 450001China College of Chemistry Zhengzhou UniversityZhengzhou 450001China College of Science Henan Agricultural UniversityZhengzhou 450002China Department of Chemistry Tsinghua UniversityBeijing 100084China National Engineering Lab.for Biomass Chemical Utilization Institute of Chemical Industry of Forest ProductsCAFNanjing 210042China Center for Carbon-based Electronics and Key Laboratory for the Physics and Chemistry of Nanodevices Department of ElectronicsPeking UniversityBeijing 100871China

Rational design of highly active catalysts for breaking hydrogen-oxygen bonds is of great significance in energy chemical reactions involving ***,an efficient strategy for the artificial atom(RuPd)established by d-orbital coupling and adjusted by oxygen vacancy(V_(O))is verified for water *** an experimental verification,the turnover frequency of RuPd-TiO_(2)-VO(RuPdTVO)catalyst in ammonia borane hydrolysis reaches up to 2750 min^(−1)(26,190 min−1 based on metal dispersion)in the absence of alkali,exceeding the highest active catalysts(Rh-based catalysts).The d-orbital coupling effect between Ru and Pd simulates the outer electronic structure of *** transfer from V_(O) to(RuPd)constructs an electron-rich state of active sites that further enhances the ability of the artificial atom to dissociate *** work provides an effective electronic regulation strategy from V_(O) and artificial atom constructed by d-orbital coupling effect for efficient water dissociation.

关键词： ammonia borane hydrolysis d-orbital coupling oxygen vacancy artificial atom water dissociation

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Visualizing traumatic brain injury:ocular clues for diagnosis and assessment

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Neural Regeneration Research 2025年第5期20卷 1399-1400页

作者： Morteza Abyadeh Vivek Gupta Yuyi You Joao A.Paulo mehdi Mirzaei ProGene Technologies Pty Ltd SydneyNSWAustralia Department of Clinical Medicine Faculty of MedicineHealth and Human SciencesMacquarie Medical SchoolMacquarie UniversityMacquarie ParkNorth RydeSydneyNSWAustralia Department of Cell Biology Harvard Medical SchoolBostonMAUSA

Traumatic brain injury (TBI) is defined as damage to the brain resulting from an external sudden physical force or shock to the *** is considered a silent public health epidemic causing significant death and disability *** were 64,000 TBI related deaths reported in the USA in 2020,with about US$76 billion in direct and indirect medical costs annually.

关键词： diagnosis ocular injury

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Preparation of tungsten-particle-reinforced Zr-based bulk metallic glass composites by two-step spark plasma sintering:microstructure evolution,densification mechanism and mechanical properties

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Rare Metals 2024年第4期43卷 1793-1808页

作者： Yun-Fei Ma Pan Gong Mao Zhang Hui-EHu Zhen Peng Xiao Xu Xin Wang mehdi Malekan Xue-Feng Tang Lei Deng Jun-Song Jin Xin-Yun Wang State Key Laboratory of Materials Processing and Die and Mould Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan430074China Research Institute of Huazhong University of Science and Technology in Shenzhen Shenzhen518057China Department of Chemistry and Materials Naval University of EngineeringWuhan430032China School of Materials Science and Engineering Jiangsu UniversityZhenjiang212013China College of Machine Shanghai Dianji UniversityShanghai201306China School of Metallurgy and Materials Engineering College of EngineeringUniversity of TehranTehran 11155-4563Iran

A new two-step spark plasma sintering(TSS)process with low-temperature pre-sintering and high-temperature final sintering has been successfully applied to prepare the tungsten-particle(Wp)-reinforced bulk metallic glass composites(Wp/BMGCs).Compared to normal spark plasma sintering(NS),the densification rate and relative density of Wp/BMGCs can be improved by selecting TSS with appropriate sintering pressure in the low temperature pre-sintering ***,the compressive strength and plastic strain of 30%Wp/BMGCs prepared by TSS are both higher than those of the samples prepared by *** TSS process can significantly enhance the compressive strength of 30%Wp/BMGCs by 12%and remarkably increase the plastic strain by 50%,while the trend is completely opposite for 50%Wp/***-in situ experiments and finite element simulations reveal that uneven temperature distribution among particles during low-temperature pre-sintering causes local overheating at contact points between particles,accelerating formation of sintering neck between particles and plastic deformation of *** the volume fraction of Wp is low,TSS can improve the interface bonding between particles by increasing the number of sintering *** makes the fracture mode of Wp/BMGCs being predominantly transgranular ***,as the volume fraction of Wp increases,the adverse effects of Wp plastic deformation are becoming more and more *** aggregated Wp tends to form a solid"cage structure"that hinders the bonding between particles at the interface;correspondingly,the fracture behavior of Wp/BMGCs is mainly dominated by intergranular ***,reducing the sintering pressure during the low-temperature pre-sintering stage of TSS has been shown to effectively decrease plastic deformation in Wp,resulting in a higher degree of densification and better mechanical properties.

关键词： Bulk metallic glass composites Tungsten particle Two-step spark plasma sintering Densification mechanism Mechanical properties

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An Improved Coupled Level Set and Continuous Moment-of-Fluid Method for Simulating Multiphase Flows with Phase Change

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Communications on Applied Mathematics and Computation 2024年第2期6卷 1034-1069页

作者： Zhouteng Ye Cody Estebe Yang Liu mehdi Vahab Zeyu Huang Mark Sussman Alireza Moradikazerouni Kourosh Shoele Yongsheng Lian Mitsuhiro Ohta M.Yousuff Hussaini ZJUI Institute Zhejiang UniversityHaining 314400ZhejiangChina Department of Mathematics Florida State UniversityTallahasseeUSA Department of Mechanical Engineering Florida State UniversityTallahasseeUSA Mechanical and Aerospace Engineering Mathworks NatickMAUSA School of Aerospace Engineering Tsinghua UniversityBeijing 100084China Department of Mechanical Engineering University of LouisvilleLouisvilleUSA Department of Mechanical Science Tokushima UniversityTokushimaJapan

An improved algorithm for computing multiphase flows is presented in which the multimaterial Moment-of-Fluid(MOF)algorithm for multiphase flows,initially described by Li et al.(2015),is enhanced addressing existing MOF difficulties in computing solutions to problems in which surface tension forces are crucial for understanding salient flow *** Continuous MOF(CMOF)method is motivated in this *** CMOF reconstruction method inherently removes the"checkerboard instability"that persists when using the MOF method on surface tension driven multiphase(multimaterial)*** CMOF reconstruction algorithm is accelerated by coupling the CMOF method to the level set method and coupling the CMOF method to a decision tree machine learning(ML)*** flow examples are shown in the two-dimensional(2D),three-dimensional(3D)axisymmetric"RZ",and 3D coordinate *** include two material and three material multiphase flows:bubble formation,the impingement of a liquid jet on a gas bubble in a cryogenic fuel tank,freezing,and liquid lens dynamics.

关键词： Moment-of-Fluid(MOF) Surface tension Two phase flow Phase change Deforming boundaries with change(s)in topology Two-dimensional(2D) Three-dimensional(3D)axisymmetric 3D

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巴基斯坦学生汉语结构词“的、地、得”偏误及教学研究

巴基斯坦学生汉语结构词“的、地、得”偏误及教学研究

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作者： Syed Muhammad Baqir mehdi 四川师范大学

学位级别：硕士

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Impacts of radiation therapy on quality of life and pain relief in patients with bone metastases

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World Journal of Orthopedics 2024年第9期15卷 841-849页

作者： Armin Hoveidaei mehdi Karimi Vida Khalafi Patrick Fazeli Amir Human Hoveidaei Students’Scientific Research Center Exceptional Talents Development CenterTehran University of Medical SciencesTehran ***Iran Bogomolets National Medical University Kyiv 01601Ukraine Student Research Committee Jahrom University of Medical SciencesJahrom ***Iran Brown University ProvidenceRI 02912United States International Center for Limb Lengthening Rubin Institute for Advanced OrthopedicsSinai Hospital of BaltimoreBaltimoreMD 21215United States

Bone metastases(BM)are a common complication in advanced cancer patients,significantly contributing to morbidity and mortality due to their ability to cause pain,fractures,and spinal cord *** therapy(RT)is vital in managing these complications by targeting metastatic lesions to ease pain,improve mobility,and reduce the risk of skeletal-related events such as *** supports the effectiveness of RT in pain relief,showing its ability to provide significant palliation and lessen the need for opioid painkillers,thereby enhancing the overall quality of life(QoL)for patients with ***,optimizing RT outcomes involves considerations such as the choice of radiation technique,dose fractionation schedules,and the integration of supportive care measures to mitigate treatment-related side effects like fatigue and skin *** factors highlight the importance of personalized treatment planning tailored to individual patient needs and tumor *** mini-review aims to provide comprehensive insights into the multifaceted impacts of RT on pain management and QoL enhancement in BM patients,with implications for refining clinical practices and advancing patient care through the synthesis of findings from various studies.

关键词： Radiation therapy Radiotherapy Quality of life Pain relief Bone metastases Bone cancer

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Late-onset Very long-chain acyl-CoA dehydrogenase deficiency diagnosis complicated by fulminant myocarditis in adult patient

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Journal of Intensive Medicine 2024年第3期4卷 400-402页

作者： Martin Gérard Clair Douillard Julien Poissy mehdi Marzouk Christophe Vinsonneau Intensive Care Unit Centre Hospitalier de Bethune-BeuvryBethuneFrance Endocrinology diabetologymetabolism departmentLille reference centre of inborn errors of metabolismLille University HospitalLilleFrance Inserm U1285 CHU LillePôle de réanimationCNRSUMR 8576-UGSF-Unitéde Glycobiologie Structurale et FonctionnelleUniv.LilleLilleFrance

Introduction A 21-year-old woman presented to the emergency department with fatigue,abdominal pain and *** physical activity in school was strictly *** had no family medical history and no personal history but reported frequent episodes of nausea and vomiting lasting 2 to 7 days during the past two years,as well as a weight loss of 9 kg due to reactive anorexia(Body Mass Index 17.5),without triggering factors or *** gastrointestinal symptoms led to the detection of isolated elevated transaminases(aspartate aminotransferase[AST]190 U/L and alanine aminotransferase[ALT]170 U/L);however,the patient did not pursue the proposed etiological *** has been using cannabis once a day for several years,with an increase in consumption over the past year,but no *** reported no other recent change in her habits.

关键词： diagnosis patient elevated

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角巩膜镜对圆锥角膜患者视力和角膜参数的影响

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国际眼科杂志 2024年第3期24卷 333-337页

作者： Ali Ayatollahi Haleh Kangari Saeed Rahmani Seyyed mehdi Tabatabaie Shahid Beheshti医科大学康复学院眼视光系伊朗德黑兰*** Shahid Beheshti医科大学康复学院伊朗德黑兰***

目的:探讨配戴角巩膜接触镜对圆锥角膜患者视力和角膜参数的影响。方法:前瞻性研究。共纳入43例(83眼)圆锥角膜患者。配戴角巩膜接触镜,并分别在戴镜前、戴镜3、6 mo后行裂隙灯检查、客观验光和主观验光、裸眼视力(UCVA)和最佳矫正视力(... 详细信息

目的:探讨配戴角巩膜接触镜对圆锥角膜患者视力和角膜参数的影响。方法:前瞻性研究。共纳入43例(83眼)圆锥角膜患者。配戴角巩膜接触镜,并分别在戴镜前、戴镜3、6 mo后行裂隙灯检查、客观验光和主观验光、裸眼视力(UCVA)和最佳矫正视力(BCVA)、角膜曲率(Kmax、K1和K2)、中央角膜厚度和内皮细胞计数检查。结果:配戴6 mo框架眼镜后平均BCVA(LogMAR)为0.34±0.23,角巩膜接触镜为0.03±0.05(P<0.001)。戴镜6 mo后,Kmax由52.80±5.93 D变为51.51±5.64 D(P<0.001),角膜中央厚度由483.84±34.69μm变为476.28±35.38μm(P<0.001),角膜中央细胞计数由2559.18±275.7 cells/mm^(2)变为2572.73±274.3 cells/mm^(2)(P<0.001)。结论:临床中角膜参数未发生明显变化,角巩膜镜可显著提高视力,且可安全用于圆锥角膜患者。

关键词：角巩膜接触镜圆锥角膜角膜地形图角膜厚度

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Special Column on Recent Advances in PCMs as Thermal Energy Storage in Energy Systems

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Journal of Thermal Science 2024年第2期33卷 395-395页

作者： Mohammad Hossein AHMADI Tingzhen MING Marc A.ROSEN S.A.SHERIF Mohammad mehdi RASHIDI Shahrood University of Technology Iran Wuhan University of Technology China University of Ontario Institute of Technology Canada University of Florida USA University of Electronic Science and Technology of China China

Thermal energy storage technology has the advantages of high energy storage density,small size,and high energy conversion *** is one of the key energy storage technologies and an important way to achieve carbon peaking and carbon neutrality *** change materials (PCMs) offer this opportunity to store high amount of energy and release it in the form of latent heat when needed,and therefore have the advantage of being capable to alleviate the intrinsic intermittency of renewable power production,especially in wind and solar farms.

关键词： efficiency store latent

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