检索结果-南通市图书馆

Gluten sensitive enteropathy in patients with iron deficiency anemia of unknown origin

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2008年第48期14卷 7381-7385页

作者： Farhad Zamani mehdi mohamadnejad Ramin Shakeri Afsaneh Amiri Safa Najafi Seyed Meysam Alimohamadi Seyed Mohamad Tavangar Ardeshir Ghavamzadeh Reza Malekzadeh Gastrointestinal and Liver Disease Research Centre Iran University of Medical Sciences Digestive Disease Research Centre Tehran University of Medical Sciences Hematology Oncology BMT research Center Tehran University of Medical Sciences Department of Pathology School of Medicine Tehran University of Medical Sciences

AIM: To determine the prevalence of gluten sensitive enteropathy (GSE) in a large group of patients with iron deficiency anemia (IDA) of obscure origin. METHODS: In this cross-sectional study, patients with IDA of obscure origin were screened for GSE. Anti- endomysial antibody (EMA) and tissue transglutamin- ase antibody (tTG) levels were evaluated and duodenal biopsies were taken and scored according to the Marsh classification. The diagnosis of GSE was based on a positive serological test and abnormal duodenal histol- ogy. Gluten free diet (GFD) was advised for all the GSE patients. RESULTS: Of the 4120 IDA patients referred to our Hematology departments, 206 (95 male) patients were found to have IDA of obscure origin. Thirty out of 206 patients (14.6%) had GSE. The mean age of GSE pa- tients was 34.6 ± 17.03 (range 10-72 years). The female to male ratio was 1.3:1. Sixteen patients had Marsh 3,12 had Marsh 2, and 2 had Marsh 1 lesions. The sever- ity of anemia was in parallel with the severity of duode- nal lesions. Twenty-two GSE patients (73.3%) had no gastrointestinal symptoms. Fourteen GSE patients who adhered to GFD without receiving iron supplementation agreed to undergo follow up visits. After 6 mo of GFD, their mean hemoglobin levels (Hb) increased from 9.9 ± 1.6 to 12.8 ± 1.0 g/dL (P < 0.01). Interestingly, in 6 out of 14 patients who had Marsh 1/2 lesions (e.g. no villous atrophy) on duodenal biopsy, mean Hb increased from 11.0 ± 1.1 to 13.1 ± 1.0 g/dL (P < 0.01) while they did not receive any iron supplementation. CONCLUSION: There is a high prevalence (e.g. 14.6%) of GSE in patients with IDA of obscure origin. Gluten free diet can improve anemia in GSE patients who have mild duodenal lesions without villous atrophy.

关键词： Gluten sensitive enteropathy Iron deficiency anemia Anti-Tissue transglutaminase antibody Anti-endomysial antibody Gluten free diet

Phase 1 human trial of autologous bone marrow-hematopoietic stem cell transplantation in patients with decompensated cirrhosis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2007年第24期13卷 3359-3363页

作者： mehdi mohamadnejad Mehrnaz Namiri Mohamad Bagheri Seyed Masiha Hashemi Hossein Ghanaati Narges Zare Mehrjardi Saeed Kazemi Ashtiani Reza Malekzadeh Hossein Baharvand Digestive Disease Research Center Shariati Hospital Medical Sciences/ University of Tehran Tehran Iran Gastrointestinal and Liver Disease Research Center Iran University of Medical Sciences Tehran Iran Department of Stem Cells Royan Institute Tehran Iran Digestive Disease Research Center Shariati Hospital Medical Sciences/ University of Tehran Tehran Iran

AIM: To evaluate safety and feasibility of autologous bone marrow-enriched CD34+ hematopoietic stem cell Tx through the hepatic artery in patients with decompensated ***: Four patients with decompensated cirrhosis were included. Approximately 200 mL of the bone marrow of the patients was aspirated, and CD34+ stem cells were selected. Between 3 to 10 million CD34+ cells were isolated. The cells were slowly infused through the hepatic artery of the ***: Patient 1 showed marginal improvement in serum albumin and no significant changes in other test results. In patient 2 prothrombin time was decreased; however, her total bilirubin, serum creatinine, and Model of End-Stage Liver Disease (MELD) score worsened at the end of follow up. In patient 3 there was improvement in serum albumin, porthrombin time (PT), and MELD score. Patient 4 developed radiocontrast nephropathy after the procedure, and progressed to type 1 hepatorenal syndrome and died of liver failure a few days later. Because of the major side effects seen in the last patient, the trial was prematurely ***: Infusion of CD34+ stem cells through the hepatic artery is not safe in decompensated cirrhosis. Radiocontrast nephropathy and hepatorenal syndrome could be major side effects. However, this study doesnot preclude infusion of CD34+ stem cells through other routes.

关键词： Cirrhosis Bone marrow Stem cell Transplantation Quality of life Model of End-Stage Liver Disease score

Healthy ranges of serum alanine aminotransferase levels in Iranian blood donors

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2003年第10期9卷 2322-2324页

作者： mehdi mohamadnejad Akram Pourshams Reza Malekzadeh Ashraf Mohamadkhani Afsaneh Rajabiani Ali Ali Asgari Seyed Meysam Alimohamadi Hadi Razjooyan Mansooreh Mamar-Abadi Digestive Disease Research Center Tehran University of Medical SciencesTehranIran Department of Pathology School of MedicineTehran University of Medical SciencesTehranIran

AIM: The healthy ranges for serum alanine aminotransferase(ALT) levels are less well studied. The aim of this study was to define the upper limit of normal (ULN) for serum ALT levels, and to assess factors associated with serum ALT activity in apparently healthy blood donors. METHODS: A total of 1 939 blood donors were *** measurements were performed for all cases using the same laboratory method. Healthy ranges for ALT levels werecomputed from the population at the lowest risk for liver disease. Univariate and multivariate analyses were performed to evaluate associations between clinical factors and ALT ***: Serum ALT activity was independently associated with body mass index (BMI) and male gender, but not associated with age. Association of ALT with BMI was more prominent in males than in females. Upper limit of normal for non-overweight women (BMI of less than 25) was 34 U/L,and for non-overweight men was 40 U/***: Serum ALT is strongly associated with sex and BMI. The normal range of ALT should be defined for male and female separately.

关键词： Adolescent Adult Age Distribution Aged Alanine Transaminase Blood Donors Body Mass Index Chemistry, Clinical numerical data Child Female Humans Iran Logistic Models Male Middle Aged Reference Values Sex Distribution

Data-Based Filters for Non-Gaussian Dynamic Systems With Unknown Output Noise Covariance

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

IEEE/CAA Journal of Automatica Sinica 2024年第4期11卷 866-877页

作者： Elham Javanfar mehdi Rahmani the Department of Electrical Engineering Imam Khomeini International UniversityQazvin ***Iran

This paper proposes linear and nonlinear filters for a non-Gaussian dynamic system with an unknown nominal covariance of the output *** challenge of designing a suitable filter in the presence of an unknown covariance matrix is addressed by focusing on the output data set of the *** that data generated from a Gaussian distribution exhibit ellipsoidal scattering,we first propose the weighted sum of norms(SON)clustering method that prioritizes nearby points,reduces distant point influence,and lowers computational ***,by introducing the weighted maximum likelihood,we propose a semi-definite program(SDP)to detect outliers and reduce their impacts on each *** these weights paves the way to obtain an appropriate covariance of the output ***,two filtering approaches are presented:a cluster-based robust linear filter using the maximum a posterior(MAP)estimation and a clusterbased robust nonlinear filter assuming that output noise distribution stems from some Gaussian noise resources according to the ellipsoidal *** last,simulation results demonstrate the effectiveness of our proposed filtering approaches.

关键词： Data-based filter maximum likelihood estimation unknown covariance weighted maximum likelihood estimation weighted sum-of-norms clustering

Reinforcement Learning-Empowered Graph Convolutional Network Framework for Data Integrity Attack Detection in Cyber-Physical Systems

在线全文

学校读者我要写书评

暂无评论

CSEE Journal of Power and Energy Systems 2024年第2期10卷 797-806页

作者： Edeh Vincent mehdi Korki mehdi Seyedmahmoudian Alex Stojcevski Saad Mekhilef School of Science Computingand Engineering TechnologiesSwinburne University of TechnologyMelbourneAustralia

The massive integration of communication and information technology with the large-scale power grid has enhanced the efficiency, safety, and economical operation of cyber-physical systems. However, the open and diversified communication environment of the smart grid is exposed to cyber-attacks. Data integrity attacks that can bypass conventional security techniques have been considered critical threats to the operation of the grid. Current detection techniques cannot learn the dynamic and heterogeneous characteristics of the smart grid and are unable to deal with non-euclidean data types. To address the issue, we propose a novel Deep-Q-Network scheme empowered with a graph convolutional network (GCN) framework to detect data integrity attacks in cyber-physical systems. The simulation results show that the proposed framework is scalable and achieves higher detection accuracy, unlike other benchmark techniques.

关键词： Deep reinforcement learning graph convolutional network heterogeneous smart grid network

A novel mitigation measure for normal fault-induced deformations on pile-raft systems

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Earthquake Engineering and Engineering Vibration 2024年第1期23卷 15-33页

作者： Mohammadreza Jahanshahi Nowkandeh mehdi Ashtiani Faculty of Civil Engineering Babol Noshirvani University of TechnologyBabolIran

Evidence from recent earthquakes has shown destructive consequences of fault-induced permanent ground movement on *** observations have increased the demand for improvements in the design of structures that are dramatically vulnerable to surface fault *** this study a novel connection between the raft and the piles is proposed to mitigate the hazards associated with a normal fault on pile-raft systems by means of 3D finite element(FE)*** embarking on the parametric study,the strain-softening constitutive law used for numerical modeling of the sand has been validated against centrifuge test *** exact location of the fix-head and unconnected pile-raft systems relative to the outcropping fault rupture in the free-field is parametrically investigated,revealing different failure *** performance of the proposed connection for protecting the pile-raft system against normal fault-induced deformations is assessed by comparing the geotechnical and structural responses of both types of *** results indicate that the pocket connection can relatively reduce the cap rotation and horizontal and vertical displacements of the raft in most *** proposed connection decreases the bending moment response of the piles to their bending moment capacity,verging on a fault offset of 0.6 m at bedrock.

关键词： normal fault rupture failure mechanism pile-raft system pocket connection finite element modeling

On the occurrence of Neoplanorbulinella Matsumaru, 1976(Foraminifera) from the late Oligocene of Central Iran(Qom Formation):Palaeobiogeographic implications

在线全文

学校读者我要写书评

暂无评论

Journal of Palaeogeography 2024年第1期13卷 80-91页

作者： mehdi Sarfi Mohsen Yazdi-Moghadam School of Earth Sciences Damghan UniversityDamghan ***Iran National Iranian Oil Company Exploration Directorate Sheikh Bahaie SquareTehran ***Iran

The shallow marine carbonates of the upper Oligocene Qom Formation yielded several occurrences of the foraminiferan genus Neoplanorbulinella Matsumaru. Neoplanorbulinella saipanensis Matsumaru has so far been recorded from the late Eocene-early Miocene of Japan and late Oligocene of NE Italy whereas N. malatyaensis Gedik is only reported from the Oligocene from its type locality in the Malatya Basin, eastern Turkey. The new records reported here from the Qom Formation indicate that both species occur in the Dobaradar section, ca. 10 km south of the city of Qom in North-Central Iran. The palaeogeographic distribution of these two species therefore has to be extended as far as the palaeolongitude of current Central *** accompanying larger benthic foraminifers, including Miogypsinoides complanatus(Schlumberger),M. formosensis Yabe and Hanzawa, Spiroclypeus margaritatus(Schlumberger), Operculina complanata(Defrance), and Risananeiza pustulosa Boukhary et al., indicate the upper Chattian SBZ 23 Zone. The coexistence of the N. saipanensis and N. malatyaensis points to suitable palaeobiogeographic conditions of Central Iran to host Western and Eastern Tethyan taxa.

关键词： Larger foraminifers Planorbulinids Biostratigraphy Qom Formation Central Iran

Coupling of RANS and BEM Solvers for Simulation of Propeller Behind the Hull in Full Appended Model

在线全文

学校读者我要写书评

暂无评论

China Ocean Engineering 2024年第3期38卷 424-438页

作者： Saeed NAJAFI mehdi POURMOSTAFA LIU Peng-fei Iranian National Institute for Oceanography and Atmospheric Science(INIOAS) Tehran 14155-4781Iran Department of Maritime Engineering Amir Kabir University of TechnologyTehran 15875-4413Iran Marine Offshore and Subsea TechnologySchool of EngineeringNewcastle UniversityNewcastle upon TyneNE17RUUK

To design a propeller for ship power plant,the interaction between ship hull and propeller must be taken into *** main concern is to apply the wake effect of ship stern on the propeller *** this paper,a coupled BEM(Boundary Element Method)/RANS(Renolds-Averaged Navier−Stokes)solver is used to simulate propeller behind the hull in the self-propulsion *** motivation of this work is to develop a practical tool to design marine propulsion system without suffering long computational *** unsteady boundary element method which is also known as panel method is chosen to estimate the propeller *** wakes are treated using a time marching wake alignment ***,a RANS code coupled with VoF equation is developed to consider the ship motions and wake field effects in the problem.A coupling algorithm is developed to interchange ship wake field to the potential flow solver and propeller thrust to the RANS *** on the difference between hull resistance and the propeller thrust,a PI controller is developed to compute the propeller RPM in every time *** of the solver is carried out using the towing tank test report of a 50 m oceanography research *** factor and trust deduction coefficient are estimated ***,the wake rollup pattern of the propeller in open water is compared with the propeller in real wake field.

关键词： RANS BEM coupled method ship propeller self-propulsion wake sheet pattern

Microstructural analysis of marl stabilized with municipal solid waste and nano-MgO

在线全文

学校读者我要写书评

暂无评论

Journal of Rock Mechanics and Geotechnical Engineering 2024年第8期16卷 3258-3269页

作者： Ali Ohadian Navid Khayat mehdi Mokhberi Department of Civil Engineering Ahvaz BranchIslamic Azad UniversityAhvazIran Department of Civil Engineering Estahban BranchIslamic Azad UniversityEstahbanIran

Municipal solid waste(MSW)is accumulating over elapsed time across the world,and it is observed in many projects associated with weak soils,such as ***,effective solutions to the environmental problem are *** techniques for stabilizing marl generally use substances such as lime and cement,which could exacerbate *** this,some new stabilizers,***-MgO,are *** are large quantities of marls and MSW in Shiraz City,*** present study aims to evaluate the feasibility of using nano-MgO as a green low-carbon binder to remove MSW from the environment and make construction projects more *** drained shear tests were conducted to evaluate the mechanical behaviors of the nano-MgO treated marl specimens at high normal *** marl specimens containing MSW percentages of 15%,25%,35%,and 45%and nano-MgO percentages of 0.25%,0.5%,0.75%,and 1%,were *** is found that the marl containing 15%and 25%MSW and 0.5%nano-MgO at 28-d curing can perform cation exchange and form new cementitious *** soils with merely MSW show good performance due to the removal of the kaolinite and the formation of ***,the soil with 25%MSW and 0.5%nano-MgO shows the same strength enhancement as the specimen with the optimal nano-MgO(0.75%)through the formation of dolomite,with a 20.59%increase in strain energy(SE).

关键词： Marl Shear strength Microstructure Nano-MgO Municipal solid waste(MSW)