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Assessment of laryngologists'ratings on physician review websites

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第1期10卷 1-6页

作者： Meleeka Akbarpour Karen Tawk Madelyn Frank Alizah S.Gomez Navid Mostaghni mehdi Abouzari Department of Otolaryngology-Head and Neck Surgery University of CaliforniaIrvineUSA

Objective:To assess and characterize online ratings and comments on laryngologists and determine factors that correlate with higher ***:All the American Laryngological Association(ALA)members were queried across several online *** were normalized for comparison on a five-point Likert *** were categorized based on context and for positive/negative ***:Of the 331 ALA members,256(77%)were rated on at least one online *** all platforms,the average overall rating was 4.39±0.61(range:1.00-5.00).Specific positive ratings including“bedside manners,”“diagnostic accuracy,”“adequate time spent with patient,”“appropriate follow-up,”and“physician timeliness”had significant positive correlations to overall ratings,by Pearson's correlation(P<0.001).Long wait times had significant negative correlations to overall ratings(P<0.001).Conclusion:Online ratings and comments for laryngologists are significantly influenced by patient perceptions of bedside manner,physician competence,and time spent with the patient.

关键词： laryngologist online rating patient rating physician review website

走滑断层对裂缝分布的控制——来自离散元数值模拟的启示

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中国科学：地球科学 2024年第1期54卷 152-171页

作者：曾联波毛哲刘国平田鹤姚迎涛祖克威董少群 mehdi OSTADHASSAN 中国石油大学(北京)油气资源与探测国家重点实验室北京102249 中国石油大学(北京)地球科学学院北京102249 北京大学能源学院北京100871 中国石化中原油田分公司勘探开发研究院郑州457001 东北石油大学大庆163318

走滑断层控制的缝洞储层是塔里木盆地超深层碳酸盐岩油气勘探的主要对象,走滑断层相关裂缝分布规律对指导超深层油气勘探开发具有重要意义.本文利用离散元数值模拟方法,对6组不同排列和活动方式的走滑断层相关裂缝发育规律进行了研究,... 详细信息

走滑断层控制的缝洞储层是塔里木盆地超深层碳酸盐岩油气勘探的主要对象,走滑断层相关裂缝分布规律对指导超深层油气勘探开发具有重要意义.本文利用离散元数值模拟方法,对6组不同排列和活动方式的走滑断层相关裂缝发育规律进行了研究,并与塔里木盆地北部地表露头区走滑断层实测结果进行了对比验证.走滑断层的纯走滑段应力分布稳定,其最大主应力保持水平,且方位不变,形成的优势裂缝走向与断层面呈小角度斜交.当走滑断层的叠接段或转折段为拉分区时,其最大主应力方位由水平变为垂直,形成的优势裂缝走向与断面大角度斜交.当走滑断层的叠接段或转折段为挤压区时,其最大主应力保持水平,但应力方位随断距增加而发生明显偏转.因而在走滑断层活动早期,主要发育与走滑断层呈小角度斜交的优势裂缝;在走滑断层活动后期,主要发育与主断面平行或者反向小角度相交的裂缝.在走滑断层的不同构造部位,裂缝发育程度存在明显差异.在走滑断层端部、连接部位和主断层面处裂缝相对发育,且前两者裂缝分布范围明显大于后者.相对于走滑断层的位移量,走滑断层的主位移带对裂缝发育的影响更大.在主位移带形成之前,走滑断层相关裂缝发育带宽度和裂缝密度随位移量的增加而快速增大,而在主位移带形成之后其增速显著降低.由于主位移带在拉分区和纯走滑段形成的时间要远早于挤压区,挤压区在主位移带形成之前吸收的应变量更大,因而挤压区裂缝最发育,其次是拉分区和纯走滑段.本文研究结果有助于认识不同排列和活动方式走滑断层相关裂缝发育规律.

关键词：走滑断层天然裂缝断层转折断层叠接主位移带离散元方法

Amyloid-beta and tau protein beyond Alzheimer's disease

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Neural Regeneration Research 2024年第6期19卷 1262-1276页

作者： Morteza Abyadeh Vivek Gupta Joao A.Paulo Arezoo Gohari Mahmoudabad Sina Shadfar Shahab Mirshahvaladi Veer Gupta Christine T.O.Nguyen David I.Finkelstein Yuyi You Paul A.Haynes Ghasem H.Salekdeh Stuart L.Graham mehdi Mirzaei ProGene Technologies Pty Ltd. SydneyNSWAustralia Department of Clinical Medicine Faculty of MedicineHealth and Human SciencesMacquarie Medical SchoolMacquarie UniversityMacquarie ParkNorth RydeSydneyNSWAustralia Department of Cell Biology Harvard Medical SchoolBostonMAUSA School of Medicine Deakin UniversityGeelongVICAustralia Department of Optometry and Vision Sciences School of Health SciencesFaculty of Medicine Dentistry and Health SciencesUniversity of MelbourneParkvilleVICAustralia The Florey Institute of Neuroscience and Mental Health The University of MelbourneParkvilleVICAustralia School of Natural Sciences Macquarie UniversityMacquarie ParkNSWAustralia

The aggregation of amyloid-beta peptide and tau protein dysregulation are implicated to play key roles in Alzheimer's disease pathogenesis and are considered the main pathological hallmarks of this devastating ***,these two proteins are produced and expressed within the normal human ***,under pathological conditions,abnormal expression,posttranslational modifications,conformational changes,and truncation can make these proteins prone to aggregation,triggering specific disease-related *** studies have indicated associations between aberrant behavior of amyloid-beta and tau proteins and various neurological diseases,such as Alzheimer's disease,Parkinson's disease,and amyotrophic lateral sclerosis,as well as retinal neurodegenerative diseases like Glaucoma and age-related macular ***,these proteins have been linked to cardiovascular disease,cancer,traumatic brain injury,and diabetes,which are all leading causes of morbidity and *** this comprehensive review,we provide an overview of the connections between amyloid-beta and tau proteins and a spectrum of disorders.

关键词： amyloid-beta cancer cardiovascular diseases diabetes neurodegeneration Tau traumatic brain injury

囊型包虫病流行现状及犬抗成虫疫苗候选抗原研究进展

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中国兽医学报 2024年第2期44卷 403-412页

作者：吴小霞鄂玉婷丁静刘晓雷 mehdi Borhani 王学林刘明远吉林大学动物医学学院人兽共患病研究所人兽共患病研究教育部重点实验室吉林长春130062

棘球蚴病/包虫病(cystic echinococcosis,CE)是一种全球性的人畜共患动物源性疾病,严重威胁人类和家畜的生命。由细粒棘球蚴引起的CE在我国高发流行,免疫接种是预防该病流行的最理想途径,在过去的几十年中,许多研究已经描述了该病的保... 详细信息

棘球蚴病/包虫病(cystic echinococcosis,CE)是一种全球性的人畜共患动物源性疾病,严重威胁人类和家畜的生命。由细粒棘球蚴引起的CE在我国高发流行,免疫接种是预防该病流行的最理想途径,在过去的几十年中,许多研究已经描述了该病的保护性候选抗原及其在终末宿主和中间宿主免疫中的作用。目前EG95重组蛋白疫苗效果最好,对中间宿主羊的保护力可达到96%~100%。但终末宿主犬作为传播的核心传染源,对其仍缺乏有效的防控手段,尤其是缺乏有效的接种疫苗,因此疫苗在犬身上的潜在应用是未来研究的重点。能抑制犬体内虫体发育并减少虫体在犬肠道内产卵量的疫苗研发将有望控制包虫病在流行地区的传播,大大加快该病的控制和消除。本研究从细粒棘球绦虫的生命周期、分子流行病学、地理分布以及终末宿主犬疫苗候选抗原等方面进行系统综述,旨在对CE的传播、未来发展方向和防治提供理论参考,为加速我国在CE终末宿主疫苗的研发进程和尽早应用于防控实践奠定基础。

关键词：棘球蚴病/包虫病细粒棘球绦虫流行病学候选抗原疫苗犬

Universal silicon ring resonator for error-free transmission links

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Photonics Research 2024年第4期12卷 701-711页

作者： JUNBO ZHU WEIWEI ZHANG KE LI BHARAT PANT MARTIN EBERT XINGZHAO YAN mehdi BANAKAR DEHN T.TRAN CALLUM G.LITTLEJOHNS FUWAN GAN GRAHAM REED DAVID J.THOMSON Optoelectronics Research Centre University of SouthamptonSouthampton SO171BJUK National Key Laboratory of Materials for Integrated Circuits Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai 200050China University of Chinese Academy of Sciences Beijing 100049China Peng Cheng Laboratory ShenzhenChina

We report the design, fabrication, and characterization of a universal silicon PN junction ring resonator for C band error-free communication links operated up to 50 Gb/s with co-designed optical modulation and detection performance. The universal p-n junction ring device shows co-designed detection responsivity up to 0.84 A/W, in conjunction with a modulation efficiency of -4 V·mm and>8 d B optical modulation extinction ratio, enabling C band 50 Gb/s NRZ communication link with a bit error rate≤3×10^(-12).

关键词： Gb/s resonator communication

Hyaluronic acid algorithm-based models for assessment of liver fibrosis： translation from basic science to clinical application

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Hepatobiliary & Pancreatic Diseases International 2016年第2期15卷 131-140页

作者： Zeinab babaei Hadi Parsian Student Research Committee&Department of Biochemistry and Biophysics Babol University of Medical SciencesBabolIran Cellular and Molecular Biology Research Center Health Research InstituteBabol University of Medical SciencesBabolIran

BACKGROUND： The estimation of liver fibrosis is usually dependent on liver biopsy evaluation. Because of its disadvantages and side effects, researchers try to find non-invasive methods for the assessment of liver injuries. Hyaluronic acid has been proposed as an index for scoring the severity of fibrosis, alone or in algorithm models. The algorithm model in which hyaluronic acid was used as a major constituent was more reliable and accurate in diagnosis than hyaluronic acid alone. This review described various hyaluronic acid algorithm-based models for assessing liver *** SOURCE： A Pub Med database search was performed to identify the articles relevant to hyaluronic acid algorithmbased models for estimating liver ***： The use of hyaluronic acid in an algorithm model is an extra and valuable tool for assessing liver ***： Although hyaluronic acid algorithm-based models have good diagnostic power in liver fibrosis assessment, they cannot render the need for liver biopsy obsolete and it is better to use them in parallel with liver biopsy. They can be used when frequent liver biopsy is not possible in situations such as highlighting the efficacy of treatment protocol for liver fibrosis.

关键词： algorithm hyaluronic acid liver disease liver fibrosis

Optimally Connected Hybrid Complex Networks with Windmill Graphs Backbone

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Journal of Systems Science & Complexity 2020年第4期33卷 903-929页

作者： SAFAEI Farshad babaei Amin MOUDI Mehrnaz Faculty of Computer Science and Engineering Shahid Beheshti UniversityTehranIran School of Computer Science Institute for Research in Fundamental SciencesTehranIran Department of Computer Engineering University of Torbat HeydariehTorbat HeydariehIran

The significance of the existing analysis methods in complex networks and easy access to the ever-increasing volume of information present the emergence of proposing new methods in various fields based on complex system ideas. However, these systems are usually faced with various random failures and intelligent attacks. Due to the nature of the components’ behaviors, the occurrence of the failures and faults in their operations and the alteration of their topologies are the most important problems. Since the complex systems are usually used as the infrastructures of other networks, their robustness against failures and the adoption of suitable precautions are necessary. Moreover, the smallworld effect in most complex systems is one of the crucial structural features. The authors found that the relation between these two is not well-known and may even be in conflict in some networks. The main goal in this paper is to achieve an optimal topology by utilizing a robustness-oriented multiobjective trade-off optimization model(edge rewiring) to establish a peaceful relationship between the two requirements. By offering a proposed rewiring method with the small-world effect, which is called core-periphery Windmill property, the authors demonstrated that the generated networks are able to exhibit appropriate robustness even during intelligent attacks. The results obtained in terms of Windmill graphs are presented very good approximations to demonstrate the small-world effect. These graphs are used as the initial core in the construction of the optimized networks’ topologies.

关键词： effect. utilizing Optimal

Processing of measurement while drilling data for rock mass characterization

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International Journal of Mining Science and Technology 2016年第6期26卷 989-994页

作者： babaei Khorzoughi Mohammad Hall Robert Norman B.Keevil Institute of Mining Engineering University of British Columbia School of Mining and Petroleum Engineering University of Alberta

The information extracted from monitoring of rotary blasthole drills helps to optimize the overall mining operation. Rock hardness, drillability, blastability and specific energy of drilling are examples of parameters that have been estimated in the past using measurement while drilling techniques. In order to be able to properly utilize measurement while drilling techniques, it is important to properly collect, analyze and interpret extracted data. This paper deals with processing of measurement while drilling data such as rate of penetration, rotary speed, rotary torque and pulldown force collected from rotary blasthole *** methods are discussed to calculate a true rate of penetration which is the most important monitored drill variable for use in rock mass characterization. Then specific energy of drilling is defined and calculated based on electrical and mechanical inputs and the results are compared. The results show that specific energy of drilling can be estimated using the drill's primary drive systems' electrical responses with good accuracy when compared to values based on mechanical inputs.

关键词： Measurement while drilling Rotary blasthole drill Specific energy Rate of penetration

Surface characterization and corrosion behavior of calcium phosphate(Ca-P)base composite layer on Mg and its alloys using plasma electrolytic oxidation(PEO):A review

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Journal of Magnesium and Alloys 2021年第1期9卷 21-40页

作者： Razieh Chaharmahali Arash Fattah-alhosseini Kazem babaei Department of Materials Engineering Bu-Ali Sina UniversityHamedan 65178-38695Iran

Magnesium has been known as an appropriate biological material on account of its good biocompatibility and biodegradability properties in addition to advantageous mechanical *** and its alloys are of poor corrosion *** high corrosion rate leads to its quick decomposition in the corrosive ambiance and as a result weakening its mechanical properties and before it is repaired,it will *** corrosion and degradation rate must be controlled in the body to advance the usage of Mg and its alloys as *** techniques have been utilized to boost biological *** electrolytic oxidation(PEO)can provide porous and biocompatible coatings for implants among various *** implants are generally supposed to show enough corrosion resistance and mechanical integrity in the body *** research has been carried out in order to produce PEO coatings containing calcium phosphate *** phosphates are really similar to bone mineral composition and present great *** present study deals with the usage of calcium phosphates as biocompatible coatings applied on Mg and its alloys to study the properties and control the corrosion rate.

关键词： Mg alloys Calcium phosphate(Ca-P) Plasma electrolytic oxidation(PEO) Surface characterization Corrosion behavior