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Non chylous filarial ascites: A rare case report

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World Journal of Clinical Infectious Diseases 2015年第1期5卷 11-13页

作者： Kaivan S Shah Prasad A Bhate Dattatray Solanke Vikas Pandey meghraj a ingle Shubhada V Kane Prabha Sawant Department Of Gastroenterology LTMMC and LTMGH Sion HospitalSion West Mumbai 400022 India

Filariasis is a common health problem in tropical and subtropical regions including India. It commonly presents with lymphatic involvement in form of nonpitting pedal edema, chylous ascites, chyluria,hydrocele and lymphocele. Detection of microfilaria in ascitic fluid is an extremely uncommon finding. We present a case of non chylous ascites where microfilaria were detected in the ascitic fluid.

关键词： Microfilaria Postpartum ascites Non chylous ascites

Tissue Holding Performance of Barbed Sutures

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Journal of Donghua University(English Edition) 2007年第2期24卷 213-218页

作者： ingle Nilesh KING Martin Department of Textile & Apparel Technology & Management North Carolina State University

A new technology of knotless barbed surgical sutures has made its mark in cosmetic surgery around the world. Although this technology is still under development, it has been approved by the Federal Drug Administration in USA, and is now used for facelift and eyelid ptosis procedures. The objectives of this study were to review the different types of knotless sutures, assess the tissue holding capacity of barbed sutures and perform image analysis to better understand the mechanism of energy absorption by the barbs under loading by the forces of surrounding tissues. A two dimensional finite element analysis was also performed to identify the areas of stress concentration, which are the main precursors for the peeling of the barbs beyond the maximun tissue holding force for a particular polymer. It was found that barbed sutures exhibit tissue holding capacities comparable to that of knotted sutures. This technology needs to be investigated further so as to optimize the barb geometry for superior holding capacity in a variety of different tissues.

关键词： barb suture surgical finite element analysis image analysis

Primary splenic lymphoma:Current diagnostic trends

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World Journal of Clinical Cases 2016年第12期4卷 385-389页

作者： Sachin B ingle Chitra R Hinge(ingle) Department of Pathology MIMSR Medical College Department of Physiology MIMSR Medical College

The primary splenic lymphoma is extremely uncommon, can present with grave complications like hypersplenismand splenic rupture. In view of vague clinical presentation, it is difficult to arrive at the diagnosis. In such circumstances, histopathological diagnosis is very important. A precise diagnosis can only be made on histopathology and confirmed on *** splenectomy is preferred as an effective therapeutic and diagnostic tool in cases with giant splenomegaly. Core biopsy is usually not advised due to a high risk of post-core biopsy complications in view of its high vascularity and fragility. Aim behind highlighting the topic is to specify that core biopsy/ fine needle aspiration cytology can be used as an effective diagnostic tool to arrive at correct diagnosis to prevent untoward complications related to disease and treatment. Anticoagulation therapy is vital after splenectomy to avoid portal splenic vein thrombosis.

关键词： Splenic lymphoma Biopsy Immunohistochemistry

Epithelial cysts of the spleen:A minireview

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World Journal of Gastroenterology 2014年第38期20卷 13899-13903页

作者： Sachin B ingle Chitra R Hinge (ingle) Swapna Patrike Department of Pathology MIMSR Medical College Department of Physiology MIMSR Medical College

Primary splenic epithelial cyst is an unusual event in everyday surgical practice with about 800 cases reported until date in the English literature. Splenic cysts may be parasitic or non-parasitic in origin. Nonparasitic cysts are either primary or secondary. Primary cysts are also called true,congenital,epidermoid or epithelial cysts. Primary splenic cysts account for 10% of all benign non-parasitic splenic cysts and are the most frequent type of splenic cysts in children. Usually,splenic cysts are asymptomatic and can be found incidentally during imaging techniques or on laprotomy. The symptoms are related to the size of cysts. When they assume large sizes,they may present with fullness in the left abdomen,local or referred pain,symptoms due to compression of adjacent structures(like nausea,vomiting,flatulence,diarrhoea) or rarely thrombocytopenia,and occasionally complications such as infection,rupture and/or haemorrhage. The preoperative diagnosis of primary splenic cysts can be ascertained by ultrasonography(USG),computed tomography or magnetic resonance imaging,although the wide use of USG today has led to an increase in the incidence of splenic cysts by 1%. However,careful histopathological evaluation along with immunostaining for presence of epithelial lining is mandatory to arrive at the diagnosis. The treatment has changed drastically from total splenectomy in the past to splenic preservation methods recently.

关键词： Epithelial cyst Spleen Diagnosis Splenectomy Laporoscopy

Energy-aware VM migration using dragonfly–crow optimization and support vector regression model in Cloud

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International Journal of Modeling, Simulation, and Scientific Computing 2018年第6期9卷 19-42页

作者： Nitin S.More Rajesh B.ingle Department of Computer Engineering Pune Institute of Computer Technology(PICT)SPPU Pune 411043MaharashtraIndia

Nowadays,virtual machine migration(VMM)is a trending research since it helps in balancing the load of the Cloud *** VMM-based strategies defined in the literature have considered various metrics,such as load,energy,and migration cost for balancing the load of the *** paper introduces a novel VMM strategy by considering the load of the Cloud *** important aspects of the proposed scheme are the load prediction through the support vector regression(SVR)and the optimal VM placement through the proposed dragonfly-based crow(D-Crow)optimization *** proposed D-Crow optimization algorithm is developed by incorporating crow search algorithm(CSA)into dragonfly algorithm(DA).Also,the proposed VMM strategy defines a load balancing model based on the energy consumption,load,and the migration cost to achieve the energy-aware *** simulation of the proposed VMM strategy is done based on the metrics such as load,energy consumption,and the migration *** the results,it can be shown that the proposed VMM strategy surpassed other comparative models by achieving the minimum values of 7.3719%,10.0368%,and 11.0639%for the load,energy consumption,and migration cost,respectively.

关键词： Virtual machine migration load balancing load prediction optimal VM placement energy awareness.

Current developments of bioanalytical sample preparation techniques in pharmaceuticals

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Journal of Pharmaceutical Analysis 2022年第4期12卷 517-529页

作者： Rahul G.ingle Su Zeng Huidi Jiang Wei-Jie Fang Institute of Drug Metabolism and Pharmaceutical Analysis College of Pharmaceutical SciencesZhejiang UniversityHangzhou310058China Hangzhou Institute of Innovative Medicine Zhejiang UniversityHangzhou310016China

Sample preparation is considered as the bottleneck step in bioanalysis because each biological matrix has its own unique challenges and *** sample preparation to extract the desired analytes and remove redundant components is a crucial step in each bioanalytical *** matrix effect is a key hurdle in bioanalytical sample preparation,which has gained extensive *** sample preparation techniques have advantages over classical techniques in terms of accuracy,automation,ease of sample preparation,storage,and shipment and have become increasingly popular over the past *** objective is to provide a broad outline of current developments in various bioanalytical sample preparation techniques in chromatographic and spectroscopic *** addition,how these techniques have gained considerable attention over the past decade in bioanalytical research is mentioned with preferred *** trends in bioanalytical sample preparation techniques,including sorbent-based microextraction techniques,are primarily emphasized.

关键词： Bioanalysis Biological matrices Matrix effect Microextraction Sample preparationtechnique

Photodynamic therapy of oral leukoplakia and orallichen planus using methylene blue:A pilot study

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Journal of Innovative Optical Health Sciences 2015年第1期8卷 95-105页

作者： Savarimuthu Wilfred Prasanna Ekta ingle Prakasa Rao Aruna Chidambaranathan Pravada Dornadula Koteeswaran S.Ganesan Department of Medical Physics Anna University Chennai-600025India Department of Oral Medicine and Radiology Meenakshi Ammal Dental College Maduravoyal Chennai-600095India Department of Oral Medicine and Radiology Sathyabama University Dental College Chennai-600119India

Premalignant lesions like oral lichen planus(OLP),oral leukoplakia(OL)has a fair probability of transforming into malignancy and they are perverse toward conventional ***-namic therapy(PDT)has been considered as an alternative/complimentary therapeutic mo-dality for the management of premalignant *** this study,methylene blue mediated photodynamic therapy(MB-PDT)was used as a possible alternative method for the treatment of OLP and OL.A total of 15 OLP lesions and 13 OL lesions were enrolled in the *** patients were irradiated 1using metal halide lamp filtered at 630土10nm,with a light exposure dose of 120 J/cm^(2) per *** the OLP lesions,MB-PDT was performed once a week for four weeks and for the OL lesions,MB-PDT was performed twice a week for three *** were evaluated pre-and post-and at follow-u sessions by changes in sign and symptom scores,and size of *** have observed a 53.3%of complete reduction in the treated OLP lesions and their decrease in size,sign and symptom score after treatment and at follow-up session was statistially *** have also observed complete response for one OL lesion of the 13 treated *** result indicates that MB-PDT is an effective modality in management of OLP and *** the two types of premalignancies treated with MB-PDT,OLP lesions responded much better than that of OL.

关键词： Photodynamic therapy methylene blue oral lichen planus oral leukoplakia

Signet ring colorectal carcinoma:Do we need to improve the treatment algorithm?

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World Journal of Gastrointestinal Oncology 2016年第12期8卷 819-825页

作者： Anup Sunil Tamhankar Parag ingle Reena Engineer Munita Bal Vikas Ostwal Avanish Saklani Department of Surgical Oncology Tata Memorial Centre Department of Radiotherapy Tata Memorial Centre Department of Surgical Pathology Tata Memorial Centre Department of Medical Oncology Tata Memorial Centre Department of Gastro-Intestinal Surgery Tata Memorial Centre

AIMTo elaborate about this peculiar variant from a tertiary cancer center from India. METHODSIt’s a retrospective study (2011-2014) of all patients diagnosed with signet ring colo-rectal cancer (SRCC). Various clinico-pathological variables were studied. RESULTSOne hundred and seventy consecutive patients with SRCC were diagnosed (11.4% of all colorectal cancers). Median Age of the cohort was 41 years. Most common location was recto-sigmoid area (54.7%). Majority patients presented in stage III and IV (91.2%). Most of the stage IV patients had isolated peritoneal metastases (86.5%). Colonic tumors had higher incidence of peritoneal metastases (91.8% vs 83.3%) as well as isolated peritoneal recurrences (37.5% vs 16.7%) than rectal primaries. Thirty-seven point five percent of patients recurred after curative surgery. Amongst them 63.63% patients had isolated peritoneal recurrences. Circumferential resection margin (CRM) was involved in 17.9% patients. Median relapse free survival (RFS) and overall survival (OS) of the cohort were 14.9 and 18.13 mo respectively. CRM involvement, colonic primary were associated with poorer RFS and OS. CONCLUSIONSRCC has predilection for peritoneal dissemination. More aggressive and/or extended chemotherapy schedules as well as prophylactic hyperthermic intra-peritoneal chemotherapy at the time of primary surgery may be attempted in these patients.

关键词： Colorectal cancer Signet ring cell carcinoma Peritoneal metastases Hyperthermic intra-peritoneal chemotherapy

Thulium laser coagulation for venous malformations of glans penis

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Asian Journal of Urology 2016年第2期3卷 110-111页

作者： Sanjay Kolte Parag ingle Meenal Kolte Sonal Bhuyar Sparsh Urology&Kidney Hospital Balraj MargDhantoliNagpurIndia

Vascular anomalies of the glans penis are very uncommon and have a sparse mention in the literature[1e3].Nd:YAG laser has been mentioned as a treatment of choice[3].The thulium laser has not been reported for its use ... 详细信息

关键词： Nd:YAG laser mentioned