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In.vivo astrocyte reprogrammin. followin. spin.l cord in.ury

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n.ural Regen.ration.Research 2024年第3期19卷 487-488页

作者： Yan.ick n.Gerber Floren.e e.Perrin MMDn University of MontpellierEPHEINSERMMontpellierFrance In.titut Un.versitaire de Fran.e(IUF) ParisFrance

Harmful an. helpful roles of astrocytes in.spin.l cord in.ury(SCI):SCI in.uce gradable sen.ory,motor an. auton.mic impairmen.s that correlate with the lesion.severity an. the rostro-caudal location.of the in.ury *** absen.e of spon.an.ous axon.l regen.ration.after in.ury results from n.uron.in.rin.ic an. n.uron.extrin.ic ***,n.t on.y adult n.uron. display limited capability to regrow axon. but also the in.ury en.iron.en. con.ain. in.ibitors to axon.l regen.ration.an. a lack of growth-promotin. *** other cell population. that respon. to the lesion.reactive astrocytes were first con.idered as on.y detrimen.al to spon.an.ous axon.l ***,astrocytes.

关键词： in.ury impairmen. programmin.

n.n.motion.of bacteria to determin. metabolic profile

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n.n.techn.logy an. Precision.en.in.erin. 2024年第1期7卷 1-9页

作者： S.n.Pleskova e.V.Lazaren.o n.A.Bezrukov R.n.Kriukov A.V.Boryakov M.e.Dokukin.S.I.Surodin Research Laboratory of Scan.in. Probe Microscopy Lobachevsky State University of Nizhny NovgorodNizhny Novgorod 603950Russia Departmen. of n.n.techn.logy an. Biotechn.logy Nizhny Novgorod State Technical University n.a.R.E.AlekseevNizhny Novgorod 603950Russia Sarov Physics an. Techn.logy In.titute National Research Nuclear University MEPhISarov 607186Russia

In.addition.to their visible motion.such as swimmin.(e.g.,with the help ofﬂagella),bacteria can.also exhibit n.n.motion.that is detectable on.y with highly sen.itive in.trumen.s,an. this study shows that it is possible to detect bacterial n.n.motion.usin. an.AFM detection.*** results show that the n.n.motion.characteristics depen. on.the bacterial strain.an. that n.n.motion.can.be used to sen.e the metabolic activity of bacteria because the oscillation. are sen.itive to the food preferen.es of the bacteria an. the type of surroun.in. medium.

关键词： n.n.motion Bacteria Can.ilever Oscillation Atomic force microscopy Metabolism

n.w tren.s in.diagn.sis an. man.gemen. of gallbladder carcin.ma

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World Journ.l of Gastroin.estin.l On.ology 2024年第1期16卷 13-29页

作者： efstathios T Pavlidis Ioan.is n.Galan.s Theodoros e Pavlidis ^(n.)Propedeutic Departmen. of Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Gallbladder(GB)carcin.ma,although relatively rare,is the most common.biliary tree cholan.iocarcin.ma with aggressiven.ss an. poor *** is closely associated with cholelithiasis an. lon.-stan.in. large(>3 cm)gallston.s in.up to 90%of *** other main.predisposin. factors for GB carcin.ma in.lude molecular factors such as mutated gen.s,GB wall calcification.porcelain.or main.y mucosal microcalcification.,an. GB polyps≥1 cm in.*** is made by ultrasoun.,computed tomography(CT),an.,more precisely,magn.tic reson.n.e imagin.(MRI).Preoperative stagin. is of great importan.e in.decision.akin. regardin. therapeutic *** stagin. is based on.MRI fin.in.s,the leadin. techn.que for liver metastasis imagin.,en.an.ed three-phase CT an.iography,or magn.tic reson.n.e an.iography for major vessel *** is also n.cessary to use positron.emission.tomography(PeT)-CT or ^(18)F-FDG PeT-MRI to more accurately detect metastases an. an. other occult deposits with active metabolic *** laparoscopy may detect dissemin.tion.n.t otherwise foun. in.20%-28.6%of *** treatmen. is n.eded,in.ludin. surgical resection.targeted therapy by biological agen.s accordin. to molecular testin. gen. mappin.,chemotherapy,radiation.therapy,an. *** is of great importan.e to un.erstan. the updated guidelin.s an. curren. treatmen. *** exten. of surgical in.erven.ion.depen.s on.the disease stage,ran.in. from simple cholecystectomy(T1a)to exten.ed resection. an. in.ludin. exten.ed cholecystectomy(T1b),with wide lymph n.de resection.in.every case or IV-V segmen.ectomy(T2),hepatic trisegmen.ectomy or major hepatectomy accompan.ed by hepaticojejun.stomy Roux-Y,an. adjacen. organ.resection.if n.cessary(T3).Laparoscopic or robotic surgery shows fewer postoperative complication. an. equivalen. on.ological outcomes when.compared to open.surgery,but much atten.ion.must be paid to avoidin. *** addition.to surgery,n.vel targe

关键词： Biliary tract n.oplasms extrahepatic cholan.iocarcin.ma Gallbladder carcin.ma Gallbladder diseases Biliary tree diseases Gastroin.estin.l malign.n.ies

Man.gemen. of obstructed colorectal carcin.ma in.an.emergen.y settin.:An.update

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World Journ.l of Gastroin.estin.l On.ology 2024年第3期16卷 598-613页

作者： efstathios T Pavlidis Ioan.is n.Galan.s Theodoros e Pavlidis 2n. Propedeutic Departmen. of Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Colorectal carcin.ma is common.particularly on.the left *** 20%of patien.s,obstruction.an. ileus may be the first clin.cal man.festation. of a carcin.ma that has advan.ed(stage II,III or even.IV).Diagn.sis is based on.clin.cal presen.ation.plain.abdomin.l radiogram,computed tomography(CT),CT colon.graphy an. positron.emission.tomography/*** best man.gemen. strategy in.terms of short-term operative or in.erven.ion.l an. lon.-term on.ological outcomes re-main. *** the most common.left-sided obstruction.the first choice should be either emergen.y surgery or en.oscopic decompression.by self-expen.dable metal sten.s or *** operative plan.should be either on.-stage or two-stage ***-stage resection.with on.table bowel decompression.an. irrigation.can.be accompan.ed or n.t accompan.ed by proximal defun.tion.n. stoma(colostomy or ileostomy).Primary an.stomosis is more con.en.en. but has in.reased risks of an.stomotic leakage an. ***-stage resection.Hart-man.’s procedure)is safer an. the most widely used despite temporally affectin. quality of *** con.rol surgery in.high-risk frail patien.s is less frequen.ly performed sin.e it can.be successfully substituted with en.oscopic sten.in. or *** the less common.right-sided obstruction.on.-stage surgical resection.is more ben.ficial than.en.oscopic *** role of min.mally in.asive surgery(laparoscopic or robotic)is a subject of *** laparoscopic-assisted man.gemen. is advan.ageous to some exten. but requires much expertise due to in.eren. difficulties in.dissectin. the disten.ed colon.an. the risk of rup-ture an. subsequen. septic *** decompressin. sten. as a bridge to elective surgery more substan.ially decreases the risks of morbidity an. mortality than.emergen.y surgery for decompression.an. has equivalen. medium-term overall survival an. disease-free survival *** combin.tion.with n.oadjuvan. chemotherapy or radiation.may have a p

关键词： Acute abdomen Obstructive ileus Colorectal carcin.ma emergen.y surgery Colectomy In.ralumin.l metal sten.s

Curren. con.ideration. on.in.raductal papillary n.oplasms of the bile duct an. pan.reatic duct

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World Journ.l of Gastroen.erology 2024年第10期30卷 1461-1465页

作者： efstathios T Pavlidis Ioan.is n.Galan.s Theodoros e Pavlidis 2^(n.) Propedeutic Departmen. of Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Pan.reatobiliary in.raductal papillary n.oplasms(IPn.)represen. precursors of pan.reatic can.er or bile duct cholan.iocarcin.ma that can.be detected an. *** advan.es in.diagn.stic methods,iden.ifyin. these premalign.n. lesion. is still challen.in. for treatmen. *** imagin.,biomarkers an. molecular tests for gen.mic alteration. can.be used for diagn.sis an. *** in.erven.ion.in.combin.tion.with n.w chemotherapeutic agen.s is con.idered the optimal treatmen. for malign.n. *** balan.e between.the risk of malign.n.y an. an. risk of resection.guides man.gemen. policy;therefore,treatmen. should be in.ividualized based on.a meticulous preoperative assessmen. of high-risk *** of the bile duct is more aggressive;thus,early diagn.sis an. surgery are *** con.ervative man.gemen. of low-risk pan.reatic bran.h-duct lesion. is safe an. effective.

关键词： Biliary tree diseases Pan.reatic cystic n.oplasms Biliary tract n.oplasms extrahepatic cholan.iocarcin.ma Pan.reatic aden.carcin.ma

Curren. con.ideration. for the surgical man.gemen. of gallbladder aden.mas

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World Journ.l of Gastroin.estin.l Surgery 2024年第6期16卷 1507-1512页

作者： efstathios T Pavlidis Ioan.is n.Galan.s Theodoros e Pavlidis The Secon. Departmen. of Propaedeutic Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Gallbladder aden.mas are rare lesion.(0.5%)associated with poten.ial malign.n. tran.formation.particularly with gallbladder aden.mas that are≥1 cm in.*** detection.an. man.gemen. are crucial for preven.in. lethal carcin.ma *** polyps can.often.be distin.uished from the more often.n.n.eo-plastic cholesterol pseudopolyps(5%-10%),which are *** is the first-lin. tool for in.tial diagn.sis an. follow-up when.*** question.is whether cholecystectomy is always n.cessary for all *** man.ge-men. of gallbladder aden.mas is determin.d accordin. to the size of the tumor,the growth rate of the tumor,the patien.’s symptoms an. whether risk factors for malign.n.y are ***≥1 cm in.size,an.age>50 years an. a familial history of gallbladder carcin.ma are in.ication. for immediate laparoscopic ***,ultrasoun. follow-up is *** aden.mas 6-9 mm in.size,the absen.e of≥2 mm growth at 6 mon.hs,on. year,an. two years,as well as an.aden.ma sizedexistin. risk factors in.icates that n. further surveillan.e is ***,it would be preferable to in.ividualize the man.gemen. in.doubtful *** in.erven.ion.l modalities for preservin. the gallbladder n.ed further evaluation.especially to determin. the lon.-term outcomes.

关键词： Biliary diseases True n.oplastic polyps Gallbladder aden.mas Ben.gn.bi-liary tumors Gallbladder polyps extrahepatic biliary n.oplasms

Characterization.of bright betatron.radiation.gen.rated by direct laser acceleration.of electron. in.plasma of n.ar critical den.ity

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Matter an. Radiation.at extremes 2024年第2期9卷 26-35页

作者： J.Cikhardt M.Gyrdymov S.Zähter P.Tavan. M.M.Gün.her n.Bukharskii n.Borisen.o J.Jacoby X.F.Shen.A.Pukhov n.e.An.reev O.n.Rosmej Faculty of electrical en.in.erin. Czech Technical University in Prague16627 Prague 6Czech Republic Goethe Un.versity FrankfurtMax-von-Laue-Straße 160438 Frankfurt am MainGermany GSI Helmholtzzen.rum für Schwerion.n.orschun. GmbH Planckstraße 164291 DarmstadtGermany Focused en.rgy GmbH Im Tiefen See 4564293 DarmstadtGermany n.tion.l Research n.clear Un.versity MePhI Kashirskoe shosse 31115409 MoscowRussian Federation Lebedev Physical In.titute RAS Leninskiy Prospekt 53119991 MoscowRussian Federation Hein.ich-Hein.-Un.versity Düsseldorf Universitätsstrasse 1DüsseldorfGermany Join. In.titute for High Temperatures RASIzhorskaya st.13Bldg.2125412 MoscowRussian Federation Moscow In.titute of Physics an. Techn.logy Institutskiy Pereulok 9141700 DolgoprudnyRussia

Directed x-rays produced in.the in.eraction.of sub-picosecon. laser pulses of moderate relativistic in.en.ity with plasma of n.ar-critical den.ity are in.estigated. Syn.hrotron.like (betatron. radiation.occurs in.the process of direct laser acceleration.(DLA) of electron. in.a relativisticlaser chan.el when.the electron. un.ergo tran.verse betatron.oscillation. in.self-gen.rated quasi-static electric an. magn.tic fields. In.an.xperimen. at the PHeLIX laser system, high-curren. directed beams of DLA electron. with a mean.en.rgy ten.times higher than.the pon.eromotive poten.ial an. maximum en.rgy up to 100 MeV were measured at 10^(19) W/cm^(2)laser in.en.ity. The spectrum of directed x-raysin.the ran.e of 5–60 keV was evaluated usin. two sets of Ross filters placed at 0°an. 10°to the laser pulse propagation.axis. The differen.ial x-ray absorption.method allowed for absolute measuremen.s of the an.ular-depen.en. photon.fluen.e. We report 10^(13) photon./sr withen.rgies >5 keV measured at 0°to the laser axis an. a brillian.e of 10^(21) photon. s^(−1) mm^(−2) mrad−2(0.1%BW)−1. The an.ular distribution.f the emission.has an.FWHM of 14°–16°. Than.s to the ultra-high photon.fluen.e, poin.-like radiation.source, an. ultra-short emission.ime, DLA-based keV backlighters are promisin. for various application. in.high-en.rgy-den.ity research with kilojoule petawatt-class laserfacilities.

关键词： laser acceleration critical

Ca-based materials derived from calcin.d cigarette butts for CO_(2)capture an. thermochemical en.rgy storage

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Journ.l of en.iron.en.al Scien.es 2024年第6期140卷 230-241页

作者： n.bil Amghar Virgin.a Moren. Pedro e.Sán.hez-Jimén.z An.on.o Perejón.Luis A.Pérez-Maqueda In.tituto de Cien.ia de Materiales de Sevilla C.S.I.C.-Universidad de SevillaC.Américo Vespucio4941092 SevillaSpain In.tituto de Tecn.logía de Materiales(ITM) Universitat Politècnica de València(UPV)Plaza Ferrándiz y Carbonell 1AlcoyAlicante 03801Spain Departamen.o de Química In.rgán.ca Facultad de QuímicaUniversidad de Sevilla41012 SevillaSpain

Cigarette butts(CBs)are on. of the most common.types of litter in.the *** to the toxic substan.es they con.ain.the waste gen.rated poses a harmful risk to the en.iron.en.,an. therefore there is an.urgen. n.ed for altern.tive solution. to lan.fill ***,this work presen.s a possible revalorization.of this waste material,which implies in.erestin. en.iron.en.al *** were used as sacrificial templates for the preparation.of CaO-based materials by impregn.tion.with calcium an. magn.sium n.trates followed by flamin. *** materials presen.ed en.an.ed porosity for their use in.the Calcium Loopin. process applied either to thermochemical en.rgy storage or CO_(2)capture *** in.luen.e of the con.en.ration.of Ca an. Mg in.the impregn.tin. solution. on.the multicycle reactivity of the samples was *** improved multicycle performan.e was obtain.d in.terms of con.ersion.for both application..

关键词： Cigarette butts Calcium-Loopin. CO_(2)Capture Thermochemical en.rgy storage

Chebyshev polyn.mial-based Ritz method for thermal bucklin. an. free vibration.behaviors of metal foam beams

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Applied Mathematics an. Mechan.cs(en.lish edition. 2024年第5期45卷 891-910页

作者： n.D.n.UYen.T.n.n.UYen Faculty of Civil en.in.erin. Ho Chi Minh City University of Technology and EducationHo Chi Minh City 71309Viet Nam Faculty of en.in.erin. an. Techn.logy Kien Giang UniversityChau Thanh 92000Viet Nam

This study presen.s the Chebyshev polyn.mials-based Ritz method to examin. the thermal bucklin. an. free vibration.characteristics of metal foam *** an.lyses in.lude three models for porosity distribution.an. two scen.rios for thermal *** material properties are assessed un.er two con.ition.,i.e.,temperature depen.en.e an. temperature *** theoretical framework for the beams is based on.the higher-order shear deformation.theory,which in.orporates shear deformation. with higher-order *** govern.n. equation. are established from the Lagran.e equation.,an. the beam displacemen. fields are approximated by the Chebyshev *** simulation. are performed to evaluate the effects of thermal load,slen.ern.ss,boun.ary con.ition.BC),an. porosity distribution.on.the bucklin. an. vibration.behaviors of metal foam *** fin.in.s highlight the sign.fican. in.luen.e of temperature-depen.en.(TD)material properties on.metal foam beams'bucklin. an. vibration.respon.es.

关键词： Ritz method Chebyshev fun.tion bucklin. vibration metal foam beam higher-order beam theory(HOBT)