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Comparison of cross sectional optical coherence tomography images of elevated optic nerve heads across acquisition devices and scan protocols

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Eye and Vision 2018年第1期5卷 163-171页

作者： megh d.patel Fareshta Khushzad Heather E.Moss department of Ophthalmology Stanford University2370 Watson Courtsuite 200Palo AltoCA 94303USA department of Neurology and Neurological Sciences Stanford University2370 Watson Courtsuite 200Palo AltoCA 94303USA

Background:Optic nerve head measurements extracted from optical coherence tomography(OCT)show promise for monitoring clinical conditions with elevated optic nerve *** aim of this study is to compare reliability within and between raters and between image acquisition devices of optic nerve measurements derived from OCT scans in eyes with varying degrees of optic nerve ***:Wide angle line scans and narrow angle radial scans through optic nerve heads were obtained using three spectral domain(Sd)OCT devices on 5 subjects(6 swollen optic nerves,4 normal optic nerves).Three raters independently semi-manually segmented the internal limiting membrane(ILM)and Bruch’s membrane(BM)on each scan using customized *** rater segmented each scan *** were qualitatively and quantitatively ***-rater,intra-rater and inter-device reliability was assessed for the optic nerve cross sectional area calculated from the ILM and BM segmentations using intraclass correlation coefficients and graphical ***:Line scans from all devices were qualitatively *** scans for which frame rate could not be adjusted were of lower ***-rater reliability for segmentation and optic nerve cross sectional area was better than inter-rater reliability,which was better than inter-device reliability,though all ICC exceeded *** was not impacted by the degree of optic nerve ***:Sd-OCT devices acquired similar quality scans of the optic nerve head,with choice of scan protocol affecting the *** image derived markers,variability between devices was greater than that attributable to inter and intra-rater differences.

关键词： Optic nerve head Optical coherence tomography Bruch’s membrane Inner limiting membrane Comparison

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MAIN CENTRAL THRUST ZONE IN THE KATHMANdU AREA, CENTRAL NEPAL, ANd ITS TECTONIC SIGNIFICANCE

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地学前缘 2000年第S1期7卷 46-47页

作者： Kazunori Arita 1, Akira Takasu 2, megh Raj dhital 3, Kamal Raj Regmi 1,3 , Lalu Prasad Paudel 3[WT5,5”BX](1 division of Earth and Planetary Sciences, Graduate School of Science, Hokkaido University, Kita 10 Nishi 8, Kita\|ku, Sapporo 060\|08

The Himalaya, a fold\|and\|thrust belt in the northern margin of the Indian continent, is characterized by thrust tectoncis (Schelling and Arita, 1991). It consists mainly of three thrust\|bounded lithotectonic units: from south to north the Sub\|Himalayan imbricate zone, the Lesser Himalayan thrust package (LH) and the Higher Himalayan thrust sheet (HH) with the overlying Tethys Himalayan sequence. These units are separated by a series of propagated thrusts, i.e. from south to north the Himalayan Frontal Fault (HFF), Main Boundary Thrust (MBT) and Main Central Thrust (MCT). These thrusts are splays off of an underlying mid\|crustal subhorizontal d$B;d(Jollement (Main detachmen Trust or Main Himalayan Thrust), and were propagated southward with time. Among these thrusts the MCT is most important intracrustal thrust in considering the geological evolution of the Himalaya, and is controversial regarding its location and nature. In western and eastern Nepal the Higher Himalayan Crystalline sheet is thrust over the Lesser Himalayan rocks along the MCT. In the Kathmandu area of central Nepal also the high\|grade rocks of the HH with the overlying Tethyan sediments covers southward the Lesser Himalayan rocks, and form the Kathmandu nappe. In the north of the Kathmandu nappe the Higher Himalayan crystallines are skirted by the Main Central Thrust zone (MCT zone) which consists of green and black phyllites with sporadic garnet snow\|ball garnet and calcareous schist associated with characteristic mylonitic augen gneiss. The southern margin of the nappe is bounded by the Mahabharat Thrust (MT: Stoecklin, 1990) with a narrow zone of the LH which is cut by the MBT. But the relationship of the MCT in the north and the MT in the south is disputable and important (Arita et al., 1997: Rai et al., 1998: Upreti and Le Fort, 1999), and in the margin of the Kathmandu nappe the MCT zone has not been confirmed.

关键词： main central thrust zone central Nepal tectonic significance

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