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Intermediate-scale Analysis of Landscape Characteristics Affecting Edge Formation in Burned Forests in Samcheok,Korea

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Journal of Mountain Science 2014年第2期11卷 384-397页

作者： Sang-Woo LEE Myoung-Soo WON joo-mee LEE Hai-Gyoung KIM Department of Design Konkuk University Kwangjin-Gu Hwayang-DongSeoul 143-701 South Korea Division of Forest Disaster and Fire prevention Korea Forest Research Institute Graduate Program Department of Landscape Architecture & Urban Planning Texas A&M University College Station Yirakjae Landscape Studio Songdong-Gu Hongik-Dong 210Seoul 133-880 South Korea

Compared to burn interiors, edges exhibit distinct biotic and abiotic conditions that include microclimate, wind speed, sunlight levels, soil composition, moisture content, nutrient availability, population density, and species diversity. This study characterized the landscapes in which burned forest edges formed in Samcheok, Korea. Over the study area, 500-m2 grid cells were generated to capture landscape characteristics. Grid cells intersecting burn boundary lines were designated as edge, while cells without these lines were classified as the interior of burned areas. Topographic variables including slope, elevation, topographic wetness index, solar radiation index, and proportions of fuel and land use types within grid cells were computed in a geographical information system(GIS). Correlation analysis with modified t-test and regression tree analysis were performed to explore the influences of landscape variables on edge formation with avoiding spatial autocorrelation problems. The results indicated that edges formed at low elevations with mild slopes, high topographic wetness, and low solar radiation. Edges were unlikely to form in areas dominated by Japanese red pines at low elevations. Moreover, heterogeneous land use/cover types contributed significantly to edge formation. Different forest management strategies for different landscape conditions can be more effective for enhancing resilience of forests to fire. Reducing susceptible fuel types might be effective at low elevations, while enhancing forest heterogeneity might be more effective at high elevations.

关键词：景观特征森林管理尺度分析韩国土地利用类型低海拔地区土地利用覆盖火烧

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Synchronous triple occurrence of MALT lymphoma, schwannoma, and adenocarcinoma of the stomach

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World Journal of Gastroenterology 2017年第22期23卷 4127-4131页

作者： Kyeong W Choi mee joo Han S Kim Woo Y Lee Department of Surgery Seoul Paik Hospital Inje University College of Medicine Department of Pathology Ilsan Paik Hospital Inje University College of Medicine

We present a case of a 56-year-old man with 3 synchronous gastric tumors. The patient presented with melena, and 3 gastric abnormalities were detected on gastroduodenoscopic examination, including a small ulcerative lesion in the gastric antrum, a submucosal mass in the gastric body, and severe erosion in the fundus. Histological examination of biopsy samples yielded respective diagnoses of gastric adenocarcinoma, gastritis, and mucosa-associated lymphoid tissue(MALT) lymphoma. The patient first received medication to eradicate any underlying Helicobacter pylori infection, which might have been a cause of the MALT lymphoma. Four weeks later, after examination of repeat biopsy samples revealed that the MALT lymphoma had resolved, the patient underwent subtotal gastrectomy. Further histological examination of resected tissue confirmed the antrum lesion as adenocarcinoma and the body lesion as schwannoma. To our knowledge, this is the first reported case of synchronous triple primary gastric adenocarcinoma, MALT lymphoma, and schwannoma.

关键词：胃的癌症同步联系 Mucosa 的淋巴的组织淋巴瘤 Schwannoma 三倍

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Systematic review on the surgical treatment for T1 gallbladder cancer

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World Journal of Gastroenterology 2011年第2期17卷 174-180页

作者： Seung Eun Lee Jin-Young Jang Chang-Sup Lim mee joo Kang Sun-Whe Kim Department of Surgery Chung-Ang University College of Medicine Department of Surgery Seoul National University College of Medicine

AIM:To evaluate the efficacy of simple and extended cholecystectomy for mucosa(T1a) or muscularis(T1b) gallbladder(GB) cancer. METHODS:Original studies on simple and extended cholecystectomy for T1a or T1b GB cancer were searched from MEDLINE(PubMed) ,Cochrane Library,EMBase,and CancerLit using the search terms of GB,cancer/carcinoma/tumor/neoplasm. RESULTS:Twenty-nine out of the 2312 potentially relevant publications met the eligibility *** the 1266 patients with GB cancer included in the publications,706(55.8%) and 560(44.2%) had T1a and T1b GB cancer,*** cholecystectomy for T1a and T1b GB cancer was performed in 590(83.6%) and 375(67.0%) patients,respectively(P<0.01) .In most series,the treatment of choice was simple cholecystectomy for T1a GB cancer patients with a 5-year survival rate of 100%.Lymph node metastasis was detected in 10.9% of the T1b GB cancer patients and in 1.8%of the T1a GB cancer patients,respectively(P<0.01) .Eight patients(1.1%) with T1a GB cancer and 52 patients(9.3%) with T1b GB cancer died of recurrent GB cancer(P<0.01) . CONCLUSION:Simple cholecystectomy represents the adequate treatment of T1a GB *** is no definite evidence that extended cholecystectomy is advantageous over simple cholecystectomy for T1b GB cancer.

关键词：癌症患者手术治疗胆囊 MEDLINE 评价系统切除术 GB

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Diagnosis of gastric epithelial neoplasia:Dilemma for Korean pathologists

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World Journal of Gastroenterology 2011年第21期17卷 2602-2610页

作者： joon mee Kim mee-Yon Cho Jin Hee Sohn Dae Young Kang Cheol Keun Park Woo Ho Kim So-Young Jin Kyoung mee Kim Hee Kyung Chang Eunsil Yu Eun Sun Jung mee Soo Chang Jong Eun joo mee joo Youn Wha Kim Do Youn Park Yun Kyung Kang Sun Hoo Park Hye Seung Han Young Bae Kim Ho Sung Park Yang Seok Chae Kye Won Kwon Hee Jin Chang The Gastrointestinal Pathology Study Group of Korean Society of Pathologists Department of Pathology Inha University Hospital Department of Pathology Yonsei University Wonju College of Medicine Wonju Christian Hospital Department of Pathology Sungkyunkwan University School of MedicineKangbuk Samsung Medical Center Department of Pathology Chungnam National University College of Medicine Department of Pathology Sungkyunkwan University School of MedicineSamsung Medical Center Department of Pathology Seoul National University College of Medicine Department of Pathology Soonchunhyang University Hospital Department of Pathology Kosin University College of Medicine Department of Pathology University of Ulsan College of MedicineAsan Medical Center Department of Pathology The Catholic University of KoreaSeoul St.Mary's Hospital Department of Pathology Seoul National University Boramae Hospital Department of Pathology Eulji General Hospital Department of Pathology Inje University Ilsan Paik Hospital Department of Pathology Kyunghee University College of Medicine Department of Pathology Pusan National University College of Medicine Department of Pathology Inje University Seoul Paik Hospital Department of Pathology Korea Cancer Center Hospital Department of Pathology Konkuk University Medical Center Department of Pathology Ajou University School of Medicine Department of Pathology Chonbuk National University Medical School Department of Pathology Korea University College of Medicine Department of Pathology Bundang Jesaeng Hospital Department of Pathology National Cancer Center The Korean Society of Pathologists 4FThe Korean Medical Association BuildingSeoul 140-721South Korea

The histopathological diagnosis of gastric mucosal biopsy and endoscopic mucosal resection/endoscopic submucosal dissection specimens is important,but the diagnostic criteria,terminology,and grading system are not the same in the East and West.A structurally invasive focus is necessary to diagnose carcinoma for most Western pathologists,but Japanese pathologists make a diagnosis of cancer based on severe dysplastic cytologic atypia irrespective of the presence of *** the Vienna classification was introduced to reduce diagnostic discrepancies,it has been difficult to adopt due to different concepts for gastric epithelial neoplastic *** pathologists experience much difficulty making a diagnosis because we are influenced by Japanese pathologists as well as Western *** is geographically close to Korea,and academic exchanges are ***,Korean doctors are familiar with Western style medical *** a result,the terminology,definitions,and diagnostic criteria for gastric intraepithelial neoplasia are very heterogeneous in *** solve this problem,the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists has made an effort and has suggested guidelines for differential diagnosis:(1) a diagnosis of carcinoma is based on invasion;(2) the most important characteristic of low grade dysplasia is the architectural pattern such as regular distribution of crypts without severe branching,budding,or marked glandular crowding;(3) if nuclear pseudostratification occupies more than the basal half of the cryptal cells in three or more adjacent crypts,the lesion is considered high grade dysplasia;(4) if severe cytologic atypia is present,careful inspection for invasive foci is necessary,because the risk for invasion is very high;and(5) other structural or nuclear atypia should be evaluated to make a final decision such as cribriform pattern,papillae,ridges,vesicular nuclei,high nuclear/cytoplasmic ratio,loss

关键词：病理诊断粘膜上皮理学家胃粘膜韩国学术交流活动发育不良细胞学

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Dissecting Functional Regions within the Phosphorylation Domain of Cardiac Myosin Binding Protein-C

Dissecting Functional Regions within the Phosphorylation Dom...

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21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology

作者： joo-mee Hwang Yaxin Lu Brett Hambly Discipline of Pathology Bosch InstituteUniversity of SydneyN.S.WAustralia

＜正＞Cardiac myosin binding protein-C（cMyBP-C） is a Urge regulatory protein whose role in the sarcomere is not clearly *** functional region of this protein is the linker region that is located between two immunoglobulin （IgI） motifs,C1 and C2 in the N-ternimal region which contains 3 phosphorylation *** is known that phosphorylation of cMyBP-C in-

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pH-induced structural changes of surface immobilized poly (L-lysine) by two-dimensional (2D) infrared correlation study

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Chinese Chemical Letters 2015年第2期26卷 173-176页

作者： Eun joo Yoo Boknam Chae Young mee Jung Seung Woo Lee School of Chemical Engineering Yeungnam University Pohang Accelerator Laboratory Department of Chemistry Kangwon National University

This paper reports the pH-induced structural changes in the surface immobilized poly（L-lysine）（PLL）***-dimensional（2D） correlation analysis was applied to the Fourier transform infrared（FTIR）spectra of the surface-immobilized PLL film to examine the spectral changes induced by the alternations of the protonation state of the amino group in the side *** spectral changes in the FTIR spectra of the PLL film were observed between pH 7 and *** decrease in the protonation state of the amino group in the side chain induced spectral changes in the amino group as well as conformational changes in the alky]group in the side *** pH 1-8,the spectral changes in the amino and alkyl groups in the side chain occurred before those of the amide group in the main chain of the surface immobilized PLL film.

关键词： Poly(L-lysine)(PLL) Surface-immobilized polypeptide FT-IR spectroscopy 2D correlation spectroscopy

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胰腺黏液性囊腺瘤:所有有外科适应征的病人都应推荐手术切除吗?

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肝胆外科杂志 2014年第5期22卷 393-393页

作者： Jae Woo Park Jin-Young Jang mee joo Kang 张松谢坤

由于胰腺黏液性囊腺瘤具有恶变风险,所以外科手术切除经常作为治疗的首选方式。然而随着MCN临床诊治经验的积累,MCN的侵害程度低于预期。这项研究旨在通过严格的病理诊断标准再次评价来建立更令人信服的MCN的外科手术指征。方法:从1991... 详细信息

由于胰腺黏液性囊腺瘤具有恶变风险,所以外科手术切除经常作为治疗的首选方式。然而随着MCN临床诊治经验的积累,MCN的侵害程度低于预期。这项研究旨在通过严格的病理诊断标准再次评价来建立更令人信服的MCN的外科手术指征。方法:从1991年到2012年首尔国立大学附属医院选取94个经过手术治疗的MCN患者进行回顾性研究。病理结果经过经验丰富的病理专家再次评估。病历和影像学作为预测恶变的决定性因素。结果:94个病人中,4人被发现为胰腺导管内乳头黏液瘤。90 MCNs,60人中是低分化,21人是中分化,5人是高分化,4人为侵袭性癌症。CT上显示的小结节(P=0.005)和CA19-9是预测恶变的重要因素。所有MCN小于3 cm并且肿瘤指标正常的患者都是良性的,所有恶变患者CA19-9均大于10000U/ml。所有病人的5年生存率为98.8%,侵袭性的MCNs生存率为75.0%。结论:MCN恶变率较低。长期结果与组织学分期无关。因此,如果没有阳性体征,MCN<3 cm并且没有结节或异常肿瘤指标不作为手术指征。确认这个结论需要设计更为严谨的前瞻性研究。

关键词：黏液性囊腺瘤外科手术指征肿瘤指标侵袭性临床诊治经验恶变率阳性体征国立大学小结节黏液瘤

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Interleukin-24 is correlated with differentiation and lymph node numbers in rectal cancer

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World Journal of Gastroenterology 2011年第9期17卷 1167-1173页

作者： Youngmin Choi mee-Sook Roh Young-Seoub Hong Hyung-Sik Lee Won-joo Hur Department of Radiation Oncology Dong-A University School of Medicine Department of Pathology Dong-A University School of Medicine Department of Preventive Medicine Dong-A University School of Medicine

AIM:To assess the significance of interleukin(IL)-24 and vascular endothelial growth factor(VEGF)expression in lymph-node-positive rectal cancer. METHODS:Between 1998 and 2005,90 rectal adenocarcinoma patients with lymph node involvement were *** patients received radical surgery and postoperative pelvic chemoradiotherapy of 50.4-54.0 *** of 5-fluorouracil and leucovorin or levamisole was given intravenously during the first and last week of radiotherapy,and then monthly for about 6 *** of IL-24 and VEGF was evaluated by immunohistochemical staining of surgical specimens, and their relations with patient characteristics and survival were *** median follow-up of surviving patients was 73 mo(range:52-122 mo). RESULTS:IL-24 expression was found in 81 out of 90 patients;31 showed weak intensity and 50 showedstrong *** expression was found in 64 out of 90 *** and weak intensities of IL-24 expression were classified as negative expression for ***-24 expression was significantly reduced in poorly differentiated tumors in comparison with well or moderately differentiated tumors(P=0.004),N2b to earlier N stages(P=0.016),and stageⅢc to stageⅢ a orⅢb(P=0.028).The number of involved lymph nodes was also significantly reduced in IL-24-positive patients in comparison with IL-24-negative ones. There was no correlation between VEGF expression and patient *** of IL-24 and VEGF was not correlated with survival,but N stage and stages were significantly correlated with survival. CONCLUSION:IL-24 expression was significantly correlated with histological differentiation,and inversely correlated with the degree of lymph node involvement in stageⅢrectal cancer.

关键词：白细胞介素分化程度淋巴结直肠癌血管内皮生长因子 VEGF 免疫组化染色手术切除

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Metachronous bile duct cancer nine years after resection of gallbladder cancer

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World Journal of Gastroenterology 2009年第27期15卷 3440-3444页

作者： Hye Jin joo Gi Hyun Kim Won joong Jeon Hee Bok Chae Seon mee Par Sei Jin Youn Jae Woon Choi Rohyun Sung Department of Internal Medicine College of Medicine Chungbuk National UniversityGaeshindong 62 Heungdukgu Cheongju 361-711 South Korea Department of General Surgery Chungbuk National UniversityGaeshindong 62 Heungdukgu Cheongju 361-711 South Korea Department of Pathology College of Medicine Chungbuk National UniversityGaeshindong 62 Heungdukgu Cheongju 361-711 South Korea

We report a rare case of a 74-year-old man with metachronous gallbladder cancer and bile duct cancer who underwent curative resection twice, with the operations nine years apart. At the age of 65 years, the patient underwent a cholecystectomy and resection of the liver bed for gallbladder cancer. This was a well-differentiated adenocarcinoma, with negative resection margins (T2N0M0, stageB). Nine years later,during a follow-up examination, abdominal computed tomography and MRCP showed an enhanced 1.7 cm mass in the hilum that extended to the second branch of the right intrahepatic bile duct. We diagnosed thislesion as a perihilar bile duct cancer, Bismuth type.

关键词：腺癌胆囊胆道异时性断层扫描医学文献切除术胆管

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Histopathology and TB-PCR kit analysis in differentiating the diagnosis of intestinal tuberculosis and Crohn’s disease

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World Journal of Gastroenterology 2010年第20期16卷 2496-2503页

作者： joon mee Kim Hyung Kil Kim Lucia Kim Suk Jin Choi In Suh Park Jee Young Han Young Chae Chu Kye Sook Kwon Eun joo Kim Department of Pathology College of Medicine Inha University7-206 Shin-heung-Dong 3 GaJoong-GuIncheon 400-711South Korea Gastroenterology College of Medicine Inha University7-206 Shinheung-Dong 3 GaJoong-GuIncheon 400-711South Korea Department of Nano and Bio Research Daegu Gyeongbuk Institute of Science and TechnologyDeocksan-dong 110Daegu 700-742South Korea

AIM: To compare the histopathologic features of intestinal tuberculosis (ITB) and Crohn’s disease (CD) and to identify whether polymerase chain reaction for Mycobacterium tuberculosis (TB-PCR) would be helpful for differential diagnosis between ITB and ***: We selected 97 patients with established diagnoses (55 cases of ITB and 42 cases of CD) who underwent colonoscopic *** features of ITB and CD were reviewed,and eight pathologic parameters were *** cases of acid fast bacilli culture-positive specimens and 10 normal colonic tissue specimens were evaluated as the positive and negative control of the TB-PCR test,*** assays were done using two commercial kits: kit detected IS6110 and MPB64,and kit detected IS6110 only;a manual in-house PCR method was also performed on formalin-fi xed,paraffi n-embedded colonoscopic biopsy ***: Statistically significant differences were noted between ITB and CD with regard histopathologic criteria: size of granulomas (P = 0.000),giant cells (P = 0.015),caseation necrosis (P = 0.003),confluent granulomas (P = 0.001),discrete granulomas (P = 0.000),and granulomas with lymphoid cuffs (P = 0.037).However,29 cases (52.7%) of ITB showed less than fi ve kinds of pathologic parameters,resulting in confusion with *** sensitivities and specificities of the TB-PCR test by kit ,kit ,and the in-house PCR method were 88.9% and 100%,88.9% and 100%,and 66.7% and 100% in positive and negative controls,*** PCR test done on endoscopic biopsy specimens of ITB and CD were signifi cantly different with kit (P = 0.000) and kit (P = 0.000).The sensitivities and specifi cities of TB-PCR were 45.5% and 88.1%,36.4% and 100%,and 5.8% and 100%,for kit and kit and inhouse PCR method on endoscopic biopsy *** the 29 cases of histopathologically confusing CD,10 cases assayed using kit and 6 cases assayed using kit were TB-PCR positive.A combi

关键词： Intestine Tuberculosis Crohn’s disease Histopathology Polymerase chain reaction Kit IS6110 MPB64

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