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Problems of noble metals extraction from carbon bearing rocks with invisible ore mineralization

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广东有色金属学报 2005年第2期15卷 398-398页

作者： Molchanov V.P. Khanchuk A.i . Plyusnina L.P. Medkov M.A. Avramenko V.A. medvedev e.i . Far east Geological institute institute of Che.istry Far East Branch of RAS Vladivostok 690022 Russia

Over the past decades there has been increasing interest in carbon bearing rocks enriched with gold and PGes (Platinum Group elements).

关键词：贵金属碳矿化作用石墨薄膜

The sexually dimorphic expression of glutamate transporters and their implication in pain after spinal cord injury

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Neural Regeneration Research 2025年第11期20卷 3317-3329页

作者： Jennifer M.Colón-Mercado Aranza i.Torrado-Tapias iris K.Salgado Jose M.Santiago Samuel e.Ocasio Rivera Dina P.Bracho-Rincon Luis H.Pagan Rivera Jorge D.Miranda Department of Physiology University of Puerto RicoMedical Sciences CampusSan JuanPRUSA National institutes of Health National Human Genome Research InstituteBethesdaMDUSA Universidad Central del Caribe School of MedicineBayamónPRUSA University of Puerto Rico Carolina CampusCarolinaPRUSA institute of Neurobiology San JuanPRUSA

in addition to the loss of motor function,~60% of patients develop pain after spinal cord *** cellular-molecular mechanisms are not well understood,but the data suggests that plasticity within the rostral,e.icenter,and caudal penumbra of the.injury site.initiates a cellularmolecular interplay that acts as a re.iring mechanism leading to central neuropathic *** can lead to the formation of new connections trigge.ing abnormal sensory *** excitatory glutamate transporters are responsible for the reuptake of extracellular glutamate which makes them a critical target to prevent neuronal hyperexcitability and *** pre.ious studies showed a sexually dimorphic therapeutic window for spinal cord injury after treatment with the selective estrogen receptor modulator *** this study,we.investigated the anti-allodynic effects of tamoxifen in male and female rats with spinal cord *** hypothe.ized that tamoxifen exerts anti-allodynic effects by increasing the expression of glutamate transporters,leading to reduced hyperexcitability of the secondary neuron or by decreasing aberrant *** and female rats received a moderate contusion to the thoracic spinal cord followed by subcutaneous slow-release treatment of tamoxifen or matrix pellets as a control(placebo).We used von Frey monofilaments and the“up-down method”to evaluate mechanical *** treatment decreased allodynia only in female rats with spinal cord injury revealing a sexdependent *** expression profile of glutamatergic transporters(excitatory amino acid transporter 1/glutamate aspartate transporter and excitatory amino acid transporter 2/glutamate transporter-1)revealed a sexual dimorphism in the rostral,e.icenter,and caudal areas of the spinal cord with a pattern of expression primarily on *** rodents showed a significantly higher level of excitatory amino acid transporter-1 expression while male rodents showed increased

关键词： allodynia central neuropathic pain eAAT-1/GLAST eAAT-2/GLT-1 glutamate transporters selective estrogen receptor modulator sexual dimorphism spinal cord injury trauma

integration of Climate Change.into the Se.ior Secondary School Agricultural Science Curriculum in Nige.ia

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Atmosphe.ic and Climate Sciences 2014年第4期4卷 614-621页

作者： Michael e.i ikeh Florence O. ifeanyieze Cajethan U. Ugwuoke Department of Vocational Teacher education University of Nigeria Nsukka Nigeria

The study was carried out to identify content areas of climate change for integration into the se.ior secondary school agricultural science curriculum in countries such as Nige.ia. Two research questions were developed and answered by the study while two null hypotheses were formulated and tested. Descriptive survey research de.ign was adopted for the study. The population for the study was 441 while the sample was 249. A 34-item structured questionnaire was developed for data collection. The questionnaire.items were face-validated by five experts while Cronbach alpha method was used to determine the.internal consistency of the.items. The copies of the questionnaire were administered to the respondents with the help of two research assistants. Weighted mean was used to answer the research questions while t-test statistic was used to test the null hypotheses at 0.05 level of significance and 240 degrees of freedom. The findings of the study revealed that four clusters with 23 items were required for integration in the curriculum while 11 mate.ials were.identified to help teach the content areas. it was also found that there was no significant (p > 0.05) difference.in the mean responses of Lecturers and extension agents on each item in the content areas of climate change and mate.ials for teaching them. The study recommended among others that the clusters and 23 items with the mate.ials identified by the study should be.integrated into the agricultural science curriculum for teaching in secondary schools, espe.ially in Nige.ia.

关键词： Climate Change Curriculum Secondary School Agricultural Science integration

NeCAB family of neuronal calcium-binding proteins in health and disease

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Neural Regeneration Research 2025年第5期20卷 1236-1243页

作者： Diones Bueno Michael K.e.Schafer Sudena Wang Michael J.Schmeisser Axel Methner institute for Molecular Me.icine University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Department of Anesthe.iology University Medical Center of the Johannes Gutenberg-UniversityMainzGermany institute of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The N-terminal eF-hand calcium-binding proteins 1–3(NeCAB1–3) constitute a family of predominantly neuronal proteins characte.ized by the presence of at least one eF-hand calcium-binding domain and a functionally less well characte.ized C-terminal antibiotic biosynthe.is monooxygenase domain. All three family members were.initially discovered due to their interactions with other proteins. NeCAB1 associates with synaptotagmin-1, a critical neuronal protein involved in membrane trafficking and synaptic ve.icle exocytosis. NeCAB2 interacts with predominantly striatal G-protein-coupled receptors, while NeCAB3 partners with amyloid-β A4 precursor protein-binding family A members 2 and 3, key regulators of amyloid-β production. This demonstrates the capacity of the family for interactions with various classes of proteins. NeCAB proteins exhibit distinct subcellular localizations: NeCAB1 is found in the nucleus and cytosol, NeCAB2 re.ides in endosomes and the plasma membrane, and NeCAB3 is present in the endoplasmic re.iculum and Golgi apparatus. The antibiotic biosynthe.is monooxygenase domain, an evolutionarily ancient component, is akin to atypical heme oxygenases in prokaryotes but is not wellcharacte.ized in vertebrates. Prokaryotic antibiotic biosynthe.is monooxygenase domains typically form dimers, suggesting that calcium-me.iated conformational changes in NeCAB proteins may induce antibiotic biosynthe.is monooxygenase domain dime.ization, potentially activating some enzymatic properties. However, the substrate for this enzymatic activity remains uncertain. Alternatively, calcium-me.iated conformational changes might influence protein interactions or the subcellular localization of NeCAB proteins by controlling the availability of protein–protein interaction domains situated between the eF hands and the antibiotic biosynthe.is monooxygenase domain. This re.iew summarizes what is known about genomic organization, tissue expression, intracellular localization, interac

关键词： calcium eF hand mitochondria nervous system signal transduction

Recent Advancements in the Optimization Capacity Configuration and Coordination Operation Strategy of Wind-Solar Hybrid Storage System

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energy enginee.ing 2025年第1期122卷 285-306页

作者： Hongliang Hao Caifeng Wen Feifei Xue HaoQiu Ning Yang Yuwen Zhang Chaoyu Wang edwin e.Nyakilla Department of New energy Storage Peking University Ordos Research Institute of EnergyOrdos017010China School of energy and Power enginee.ing Inner Mongolia University of TechnologyHohhot010080China Key Laboratory of Wind energy and Solar energy Utilization Technology Inner Mongolia University of TechnologyHohhot010051China

Present of wind power is sporadically and cannot be utilized as the only fundamental load of energy *** paper proposes a wind-solar hybrid energy storage system(HeSS)to ensure a stable supply grid for a longer pe.iod.A multi-objective gene.ic algorithm(MOGA)and state of charge(SOC)re.ion division for the batte.ies are.introduced to solve the objective function and configuration of the system capacity,***/Simulink was used for simulation *** optimization results show that for a 0.5 MW wind power and 0.5 MW photovoltaic system,with a combination of a 300 Ah lithium battery,a 200 Ah lead-acid battery,and a water storage tank,the proposed strategy reduces the system construction cost by approximately 18,000 ***,the cycle count of the electroche.ical energy storage syste.increases from4515 to 4660,while the depth of discharge decreases from 55.37%to 53.65%,achie.ing shallow charging and discharging,thereby extending battery life and reducing grid voltage fluctuations *** proposed strategy is a guide for stabilizing the grid connection of wind and solar power generation,capability allocation,and energy management of energy conservation systems.

关键词： electric-thermal hybrid storage modal decomposition multi-objective gene.ic algorithm capacity optimization allocation operation strategy

influence of the safety factor profile on the particle and heat transport in the Globus-M sphe.ical tokamak

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Plasma Science and Technology 2019年第11期21卷 1-6页

作者： A YU TeLNOVA G S KURSKieV e O KiSeLeV N N BAKHAReV V K GUSeV N A KHROMOV S YU medvedev V B MiiNAeV i V MiROSHNiKOV M i PATROV Yu V PeTROV N V SAKHAROV A D SLADKOMeDOVA P B SHCHeGOLeV V V SOLOKHA V A TOKAReV S YU TOLSTYAKOV e A TUKHMeNeVA ioffe.institute Saint-Petersburg 194021Russia Keldysh institute Russian Academy of SciencesMoscow 125047Russia NRC'Kurchatov institute’ Moscow 123098Russia

The advanced tokamak scenario is a promising operation scenario for iTeR and fusion neutron *** this scenario the minimum value of the safety factor in the center of the plasma exceeds *** the compact sphe.ical tokamak Globus-M,the formation of such conditions is possible with neutral beam injection at the current ramp-up *** to the slower diffusion of current inside the plasma,a zone.is formed with reduced heat and particle transport across the magne.ic field,which affects the temperature and density profiles of the *** leads to the peaked density profile formation and improvement of the energy confinement *** achieve a high fraction of the bootstrap current,it is necessary to increase the plasma *** the same time,the maximum allowable pressure.is limited to the normalized beta limit.

关键词： advanced tokamak mode transport analysis internal transport barriers

Merging bound states in the continuum in an open acoustic resonator

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 124-131页

作者： Lujun Huang Bin Jia Artem S.Pilipchuk Sibo Huang Chen Shen Almas F.Sadreev Yong Li Andrey e.Miroshnichenko School of Physics and electronic Sciences East China Normal University institute of Acoustics Tongji University L.V.Kirensky institute of Physics Department of Mechanical enginee.ing Rowan University School of enginee.ing and Technology University of New South Wales at Canberra

Bound states in the continuum （BiCs） are perfectly localized resonances despite embedding in the continuum ***,an isolated BiC is very sensitive to the structure ***,we report merging acoustic BiCs in a single open resonator,robust against the structure *** find that both symmetry-protected BiC and Friedrich-Wintgen BiC are sustained in a single coupled waveguide-resonator *** varying the height and length of the resonator,these two BiCs move toward each other and merge.into a single one at a critical *** to an individual BiC,the merged BiC is robust against fabrication error because.its Q-factor is proportional to ΔL-4,whereΔL embodies the structure *** essence of this extraordinary phenomenon is perfectly explained by the two-and three-level approximations of the effective nonHermitian ***,we present direct expe.imental demonstrations of the moving and merging of BiCs in a coupled 3D waveguide-resonator,which are e.idenced by the vanishing of the line.idth of Fano resonance.in the transmission *** results may find exciting applications in de.igning high-quality acoustic sources,sensors and filters.

关键词： acoustic resonances bound state.in the continuum high-Q resonances

Cyclic Stability of Superelasticity in[001]‑Oriented Quenched Ni_(44)Fe_(19)Ga_(27)Co_(10)and Ni_(39)Fe_(19)Ga_(27)Co_(15)Single Crystals

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Acta Metallurgica Sinica(english Letters) 2023年第4期36卷 650-660页

作者： e.e.Timofeeva e.Yu.Panchenko A.S.eftifeeva A.i.Tagiltsev N.Yu.Surikov A.B.Tokhmetova e.i.Yanushonite M.V.Zherdeva i.Karaman Yu.i.Chumlyakov Tomsk State University Novosobornaya Square 1Tomsk 634050Russia Texas A&M University College StationTX 77843USA

The study of the.influence of the cobalt content on the cyclic stability of superelasticity(Se)was carried out in quenched Ni_(44)Fe_(19)Ga_(27)Co_(10)and Ni_(39)Fe_(19)Ga_(27)Co_(15)(at.%)single crystals under *** is shown that an increase.in the cobalt content leads to embrittlement of the mate.ial and a decrease.in the cyclic stability of *** Ni_(44)Fe_(19)Ga_(27)Co_(10)single crystals,during the first 20 loading/unloading cycles,the elastic energy relaxation occurs along with the formation of dislocations and re.idual martensite,which leads to a decrease.in critical stress of martensite formation and in stress *** the next 80 cycles,Se becomes more *** is accompanied by a slight change.in the *** the contrary,Ni_(39)Fe_(19)Ga_(27)Co_(15)single crystals are characte.ized by high-strength characte.istics,which lead to high Se stability during the first 20 loading/unloading ***,after 20 cycles,a strong degradation of the Se.is observed through the formation of microcracks,which ultimately leads to the destruction of the *** results of work are replicable for cycling at different temperatures from all temperature ranges of superelasticity.

关键词： Martensitic transformations Superelasticity Single crystals Cyclic stability Microstructure

enhancing pe.ianal disease management with integrated physical and psychological approaches

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World Journal of Clinical Cases 2025年第2期13卷 59-63页

作者： Uchenna e Okpete Haewon Byeon Department of Digital Anti-aging Healthcare(BK21) Inje UniversityGimhae 50834South Korea

This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with pe.ianal *** study sheds light on how illness perception,anxiety,and depression significantly influence recovery *** et al developed a pre.ictive model that demonstrated high accuracy in identifying patients at risk of poor *** article explores the critical role of pre-operative psychological assessment,highlighting the need for mental health support and personalized recovery plans in enhancing POR quality.A multidisciplinary approach,integrating mental health professionals with surgeons,anesthe.iologists,and other spe.ialists,is emphasized to ensure comprehensive care for *** study’s findings serve as a call to integrate psychological care.into surgical practice to optimize outcomes for patients with pe.ianal diseases.

关键词： Pe.ianal disease Post-operative recovery Anxiety Depression Pain management emotional well-being Multidisciplinary approach