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贵阳医学院学报 1986年第4期 314-317页

作者：李卓江贵阳医学院内科学教研室

本文通过9例患者的临床前瞻性观察探讨弥漫性血管内凝血(DIC)的早期诊断问题。结合临床及实验室检测讨论了有关早期诊断指标。

关键词：弥漫性血管内凝血实验室诊断

高风险患者经皮冠状动脉介入治疗术前应用血小板膜糖蛋白Ⅱb/Ⅲa受体拮抗剂(Clotinab^(TM))的耐受性和疗效的研究

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心血管病学进展 2009年第2期30卷 347-348页

作者： Moon JY Kim W Kim JH. Yonsei med J 耿涛（摘译）不详河北省沧州市中心医院心血管内二科

Clotinab^TM是新研制出的血小板膜糖蛋白Ⅱb/Ⅲa受体拮抗剂。本研究的目的是作为一个多中心、随机、开放性注册研究,用来评估Clotinab^TM的疗效和耐受性,结果预计将与ReoPro^TM相同,即在高风险的病人拟行经皮冠状动脉介入治疗(PCI)术前... 详细信息

Clotinab^TM是新研制出的血小板膜糖蛋白Ⅱb/Ⅲa受体拮抗剂。本研究的目的是作为一个多中心、随机、开放性注册研究,用来评估Clotinab^TM的疗效和耐受性,结果预计将与ReoPro^TM相同,即在高风险的病人拟行经皮冠状动脉介入治疗(PCI)术前应用Clotinab^TM可预防缺血性心脏并发症的发生。[第一段]

关键词：血小板膜糖蛋白Ⅱb/Ⅲa受体拮抗剂经皮冠状动脉介入治疗术前应用耐受性高风险疗效心脏并发症多中心

Human immunodeficiency virus type 1 tat accelerates kaposi sarcoma-associated herpesvirus kaposin A-mediated tumorigenesis of transformed fibroblasts in vitro as well as in nude and immunocompetent mice

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南京医科大学学报（自然科学版） 2010年第1期30卷 133-133页

作者： Chen, Xiuying Cheng, Lin Jia, Xuemei Yao, Shuihong Lv, Zhigang Qin, Di Fang, Xin Lu, Chun Nanjing med Univ, Dept Microbiol & Immunol, Nanjing 210029, Peoples R China.Chen, Xiuying Lu, Chun Nanjing med Univ, Lab Reprod med, Nanjing 210029, Peoples R China.Chen, Xiuying Lu, Chun Nanjing med Univ, Key Lab Pathogen Biol Jiangsu Prov, Nanjing 210029, Peoples R China.Chen, Xiuying Lu, Chun Key Lab Lab med Jiangsu Prov, Nanjing 210029, Peoples R China.Chen, Xiuying Lei, Yongliang Lishui Ctr Dis Control & Prevent, Lishui 323000, Zhejiang, Peoples R China.Cheng, Lin Huanghe Sci & Technol Coll, Dept Microbiol & Immunol, Zhengzhou 450006, Peoples R China.Zeng, Yi Youjiang med Coll Nationalities, Dept Microbiol & Immunol, Bose 533000, Peoples R China.

Kaposi sarcoma-associated herpesvirus(KSHV) is necessary but not sufficient to cause Kaposi sarcoma(KS).Coinfection with human immunodeficiency virus type 1(HIV-1), in the absence of antiretroviral suppressive therapy, drastically increases the risk of ***, we identified that HIV-1 transactivative transcription protein(Tat) was an important cofactor that activated lytic cycle replication of ***, we further investigated the potential of Tat to influence tumorigenesis induced by KSHV Kaposin A, a product of KSHV that was encoded by the open reading frame K12(a KSHV-transforming gene).By using colony formation in soft agar, H-3-TdR incorporation, cell cycle, and microarray gene expression analyses, we demonstrated that Tat enhanced proliferation as well as mitogen-activated protein kinase, signal transducer and activator of transcription 3, and phosphatidylinositol 3-kinase/protein kinase B signaling induced by Kaposin A in NIH3T3 *** experiments further demonstrated that Tat accelerated tumorigenesis by Kaposin A in athymic nu/nu *** obtained from primary tumors of nude mice succeeded inducing tumors in immunocompetent *** data suggest that Tat can accelerate tumorigenesis induced by Kaposin *** data present the first line of evidence that Tat may participate in KS pathogenesis by collaborating with Kaposin A in acquired immunodeficiency syndrome(AIDS)-related KS(AIDS-KS) *** data also suggest that the model for Kaposin and Tat-mediated oncogenesis will contribute to our understanding of the pathogenesis of AIDS-KS at the molecular level and may even be important in exploring a novel therapeutic method for AIDS-KS.

关键词：卡波西肉瘤疱疹病毒肿瘤治疗方法

用Digoxigenin标记DNA探针作基因转移山羊的整合检测

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生物技术 1992年第4期2卷 11-13,20页

作者：成国祥王捍东成勇吴维芬穆宗尧李国忠江苏农学院畜牧兽医系

对采用外源基因原核显微注射法生产的基因转移山羊,用一种新的DNA非同位素标记法即地高辛配基标记DNA探针作外源基因整合检测.结果表明:地高辛标记核酸探针能检测出基因转移动物基因组中整合的外源基因.

关键词：地高辛配基转基因整合检测山羊

Updated Meta-Analysis on Genetic Predisposition of Four Variants at NRAMP1(SLC11A1) Gene to Tuberculosis

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Updated Meta-Analysis on Genetic Predisposition of Four Vari...

Thrombosis of the Transverse Sinus: About a Clinical Observation and Review of the Literature

中华医学会第九次全国检验医学学术会议暨中国医院协会临床检验管理专业委员会第六届全国临床检验实验室管理学术会议

作者： Dong-dong Li,Xin Hu,Meng-na Zuo,Chuan-min Tao,Bing-wu Ying,Lan-lan Wang Department of lab med,West China Hospital of S.C.U.

OBJECTIVE A previous meta-analysis was performed to assess the association between variations in NRAMP1 and tuberculosis(TB) risk, but its limitations were that it did not report genotype comparative results,and not discuss the association with extra-pulmonary TB(EPTB).So, we carried out an updated meta-analysis to further investigate the association between NRAMP1 and TB susceptibility.

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International Journal of Otolaryngology and Head & Neck Surgery 2023年第3期12卷 180-186页

作者： Harouna Sanogo Kassim Diarra Nfaly Konate Mohamed Saydi Ag med Elmehdi Elansari Drissa Kaloga Bagayogo Kalifa Coulibaly Dembele Yaya Kone Fatogoma Issa Boubacary Guindo Siaka Soumaoro Doumbia Kadidiatou Mohamed Amadou Keita Reference Health Center Kalaban Koro Bamako Mali ENT Head and Neck Surgery Department University Hospital Gabriel Toure Bamako Mali Reference Health Center Common VI Bamako Mali Department of Anesthetist Resuscitation University Hospital Mother-Child Luxembourg Bamako Mali

Cerebral venous thrombosis has an unfavorable prognosis. It is a rather rare pathology concerning 3 to 5 cases per million inhabitants. The clinical symptomatology also varies according to the topography of the venous thrombosis and, in some cases, the CVT can have an unusual presentation. Progress and accessibility of non-invasive imaging currently allow early diagnosis of CVT. Brain MRI is the reference method for the diagnosis of CVT. We report a case of transverse sinus thrombosis in a 32-year-old male patient who consulted for headaches through which we want to study the etiological, clinical, paraclinical, therapeutic aspects as well as the evolutionary profile. The clinical history dates back to 2 weeks ago with frontal headaches radiating to the occipital region, throbbing of severe intensity, progressive onset and permanent evolution associated with right unilateral anterior purulent rhinorrhea. He had no nasal obstruction, epistaxis, hearing loss or other otological symptoms;no neurological deficit or notion of head trauma. Cerebral and maxillofacial computed tomography showed right maxillary sinusitis and right transverse sinus thrombosis. We carried out medical treatment based on antibiotics and analgesics without the use of anticoagulants. The evolution was favorable after four weeks of treatment. Conclusion: Transverse sinus thrombosis has a non-specific and heterogeneous clinical presentation. Headaches are the first sign. MRI and CT can help establish the diagnosis. The treatment is both etiological and symptomatic.

关键词： Transverse Sinus Thrombosis Headache Non-Surgical Treatment

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乙型肝炎母婴阻断临床管理流程

中华肝脏病杂志 2017年第4期25卷 254-256页

作者：无侯金林中国肝炎防治基金会中华医学会感染病学分会中华医学会肝病学分会南方医科大学南方医院广州510515

母婴传播是乙型肝炎病毒（HBV）的重要传播途径，加强慢性HBV感染孕妇及其所分娩婴儿的规范化管理是切断母婴传播的有效途径，为规范我国HBV母婴阻断临床管理，我们组织感染病学、肝病学、免疫学与产科学专家参照国内外公认乙型肝炎防... 详细信息

母婴传播是乙型肝炎病毒（HBV）的重要传播途径，加强慢性HBV感染孕妇及其所分娩婴儿的规范化管理是切断母婴传播的有效途径，为规范我国HBV母婴阻断临床管理，我们组织感染病学、肝病学、免疫学与产科学专家参照国内外公认乙型肝炎防治指南和最新研究成果盱”形成专家共识。

关键词：肝炎乙型母婴传播临床管理

Multi-element Ultrasound Phased Array Applicator for the Ablation of Deep-seated Tissue

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Journal of Shanghai Jiaotong university(Science) 2011年第1期16卷 55-60页

作者：吉翔沈国峰白景峰李德辉余瑛乔杉陈亚珠 Biomedical Instrument Institute Med-X Research InstituteShanghai Jiaotong University

High-intensity focused ultrasound (HIFU) has attracted increasing interests as a promising noninvasive modality for the treatment of deep tumors in the thoracic and abdominal cavity.A 90-element HIFU spherical phased array applicator operated at 1 MHz has been developed for deep tissue *** spherical array with a 5 cm wide central hole has a 21 cm diameter and an 18 cm radius of *** element distribution with unequal element spacing is used to reduce the number of *** array is constructed with piezoelectric lead zirconate titanate (PZT-8) circular elements that are 1.4 cm in diameter and have a wall with thickness of 0.2 *** array offers an effective ablating depth of at least 8 cm in the tissue for both simulations and ex vivo *** simulations demonstrate that the developed array can steer the focus with good quality of intensity distributions up to 6 mm off center over ranges from 17 to 21 cm when the water depth is set at 11 *** also present the beam focusing capability in deep tissue through a series of ex vivo experiments by measuring discoloration areas after *** results indicate that the developed array is ideal for the ablation of deep-seated tissue.

关键词： high-intensity focused ultrasound (HIFU) spherical phased array focus pattern ablation

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骨盆折之要点

中华医学杂志 1932年第6期18卷 1081-1082页

作者： med. Ann. 1921. p. 197 齐大编译部齐大编译部

Wakeley氏注意髂骨有一最厚而坚之块,起於髋臼,继斜向上後内至骶髂关节,以支持脊柱之重量。髂骨折多在此块之前或後,而不累及此块。挽言之,折断线多在骶骨之旁块或闭孔周围之骨。

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空针取活组织之检查法

中华医学杂志 1933年第4期19卷 643-644页

作者： med. Annualp. 65, 1932 齐大医学院编译部齐大医学院编译部

Martin及Ellis二氏发明取出活组织小块之新法,即用空针

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