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Agglomerate behavior in a recirculating fluidized bed with sheds： effect of ring baffles

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Particuology 2018年第3期16卷 143-151页

作者： Francisco J. Sanchez Careaga Cedric Briens Franco Berruti Jennifer McMillan Murray gray Institute for Chemicals and Fuels from Alternative Resources Western University 22312 Wonderland Rd. Hderton ON NO M2AO Canada edmonton Research Centre Syncrude Canada Ltd 9421 17th Ave Edmonton AB T6N 1H4 Canada The Petroleum Institute PO Box 2533 Abu Dhabi UAE

The radioactive particle tracking technique was used to study the effect of internal ring baffles on wet agglomerate motion inside a cold flow recirculating fluidized bed. The study found that using such a baffle on its own or above the regular sheds helps reduce the fouling of the stripper section by increasing the residence time that the agglomerates spend above the baffle, thereby reducing the release of the vapors below the baffles that cause fouling of the sheds. Adding down-comers, or flux tubes, to the ring baffles degrades the performance of the baffles, Reducing the length of the flux tubes, so that they do not reach the bottom of the baffle lip results in a further degradation in baffle performance.

关键词： Radioactive particle tracking Fluidized bed Fluid coker Baffles

Homopteran Vector Biomarkers for efficient Circulative Plant Virus Transmission are Conserved in Multiple Aphid Species and the Whitefly Bemisia tabaci

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Journal of Integrative Agriculture 2012年第2期11卷 249-262页

作者： Michelle Cilia Michael Bereman Tara Fish Michael J MacCoss stewart gray USDA-ARS Robert W. Holley Center for Agriculture and Health Tower Road Ithaca New York 14853 USA Department of Plant Pathology and Plant-Microbe Biology Cornell University Ithaca New York 14853 USA Department of Genome Sciences University of Washington Seattle Washington 98195-5065 USA

Plant viruses in the families Luteoviridae and Geminiviridae are phloem restricted and are transmitted in a persistent,circulative manner by homopteran *** fluorescence 2-D difference gel electrophoresis to compare the proteomes of F2 genotypes of Schizaphis graminum segregating for virus transmission ability,we recently discovered a panel of protein biomarkers that predict vector *** we used aphid and whitefly nucleotide and expressed sequence tag database mining to test whether these biomarkers are conserved in other homopteran *** gene homologs that shared a high degree of predicted amino acid identity were discovered in two other aphid species and in the whitefly Bemisia *** reaction monitoring mass spectrometry was used to validate the expression of these biomarkers proteins in multiple aphid vector *** conservation of these proteins in multiple insect taxa that transmit plant viruses along the circulative transmission pathway creates the opportunity to use these biomarkers to rapidly identify insect populations that are the most efficient vectors and allow them to be targeted for control prior to the spread of virus within a crop.

关键词： aphid whitefly Schizaphis graminum Bemisia tabaci Acyrthosiphon pisum Toxoptera citricida Myzuspersicae proteomics biomarker circulative transmission begomovirus luteovirus geminivirus leaflaopper,selected reaction monitoring SRM mass spectrometry targeted proteomics Skyline

Wireless data management system for environmental monitoring in livestock buildings

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Information Processing in Agriculture 2017年第1期4卷 1-17页

作者： James gray Thomas M.Banhazi Alexander A.Kist Faculty of Health Engineering and SciencesUniversity of Southern Queensland(USQ)West StreetToowoombaQLD 4350Australia National Centre for engineering in Agriculture(NCeA) University of Southern Queensland(USQ)West StreetToowoombaQLD 4350Australia

The impact of air quality on the health,welfare and productivity of livestock needs to be considered,especially when livestock are kept in enclosed *** monitoring of such environmental factors allows for the development of appropriate strategies to reduce detrimental effects of sub-optimal air quality on the respiratory health of both livestock and *** 2009,an environmental monitoring system was designed,developed and tested that allowed for the monitoring of a number of airborne *** limitation of the system was the manual collection of logged data from each *** paper identifies limitations of the current environmental monitoring system and suggests a range of networking technologies that can be used to increase *** is taken for the networking of environmental monitoring units,as well as the collection of recorded ***,the design and development of a software system that is used to collate and store recorded environmental data from multiple farms is *** order to design such a system,simplified software engineering processes and methodologies have been *** main steps taken in order to complete the project were requirements elicitation with clients,requirements analysis,system design,implementation and finally *** outcome of the project provided a potential prototype for improving the environmental monitoring system and analysis informing the benefit of the implementation.

关键词： Sensors environmental monitoring Networking Software engineering

Shifting equilibriums in Alzheimer’s disease: the complex roles of microglia in neuroinflammation, neuronal survival and neurogenesis

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Neural Regeneration Research 2020年第7期15卷 1208-1219页

作者： Sophie C. gray Kerri J. Kinghorn Nathaniel S. Woodling Institute of Healthy Ageing and Department of Genetics Evolution and Environment University College London

Alzheimer's disease is the leading cause of *** increased prevalence in developed countries,due to the sharp rise in ageing populations,presents one of the costliest challenges to modern *** order to find disease-modifying therapies to confront this challenge,a more complete understanding of the pathogenesis of Alzheimer's disease is *** studies have revealed increasing evidence for the roles played by microglia,the resident innate immune system cells of the *** the well-established roles of microglia in reacting to pathogens and inflammatory stimuli,there is now a growing literature describing both protective and detrimental effects for individual cytokines and chemokines produced by microglia in Alzheimer's disease.A smaller but increasing number of studies have also addressed the divergent roles played by microglial neurotrophic and neurogenic factors,and how their perturbation may play a key role in the pathogenesis of Alzheimer's *** we review recent findings on the roles played by microglia in neuroinflammation,neuronal survival and neurogenesis in Alzheimer's *** each case,landmark studies have provided evidence for the divergent ways in which microglia can either promote neuronal function and survival,or perturb neuronal function,leading to cell *** many cases,the secreted molecules of microglia can lead to divergent effects depending on the magnitude and context of microglial *** suggests that microglial functions must be maintained in a fine equilibrium,in order to support healthy neuronal function,and that the cellular microenvironment in the Alzheimer's disease brain disrupts this fine balance,leading to ***,an understanding of microglial homeostasis,both in health and across the trajectory of the disease state,will improve our understanding of the pathogenic mechanisms underlying Alzheimer's disease,and will hopefully lead to the development of microglial-base

关键词： adult neurogenesis Alzheimer's disease IGF-1 microglia neuroinflammation Trem2

Insight into the effects of electrochemical factors on host-guest interaction induced signature events in a biological nanopore

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纳米技术与精密工程（英文） 2020年第1期3卷 2-8页

作者： XiaojunWei Zehui Zhang XiaoqinWang Brian Lenhart Roberto Gambarini Jonathan gray Chang Liu Biomedical engineering Program University of South CarolinaColumbiaSC 29208USA Department of Chemical engineering University of South CarolinaColumbiaSC 29208USA

The signature events caused by host-guest interactions in the nanopore system can be used as a novel and characteristic signal in quantitative detection and analysis of various ***,the effect of several electrochemical factors on the host-guest interactions in nanopore still remains ***,we systematically studied host-guest interactions,especially oscillation of DNA-azide adamantane@cucurbit[6]inα-Hemolysin nanopore under varying pH,concentration of electrolytes and counterions(Li+,Na+,K+).Our results indicate correlations between the change of pH and the duration of the oscillation *** addition,the asymmetric electrolyte concentration and the charge of the counterions affects the frequency of signature events in oscillation signals,and even the integrity of the protein *** study provides insight into the design of a future biosensing platform based on signature oscillation signals of the host-guest interaction within a nanopore.

关键词： Nanopore Host-guest interaction Biosensors electrochemistry

Behavioral differences within and among populations of an African cichlid found in divergent and extreme environments

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Current Zoology 2019年第1期65卷 33-42页

作者： Richard C. Oldham Lauren M. Pintor Suzanne M. gray School of environment and Natural Resources The Ohio State University Columbus OH 43210 USA

Animals are increasingly faced with human?induced stressors that vary in space and time, thus we can expect populati on-level diverge nee in behaviors that help animals to cope with en vironme ntal change. However, empirical evidenee of behavioral trait divergence across environmental extremes is lacking. We tested for variation in behavioral traits among 2 populations of an African cichlid fish (Pseudocrenilabrus multicolor victoriae Seegers, 1990) that experience extremes of dissolved oxygen (DO) and turbidity and are known to vary in a number of physiological and life history traits associated with these stressors. Using a comm on garden reari ng experime nt, F1 progeny from wild-caught parents originating from a swamp (low DO, clear) and a river (high DO, turbid) were reared in high DO, clear water. Predator simulation assays were conducted to test for (1) variation in boldness, general activity, and foraging activity between populations,(2) differences in correlations betwee n behaviors with in and across populati ons, and (3) repeatability of behaviors. There was strong evide nee for diverge nee betwee n populati ons, with swamp fish being more bold (i.e.z leaving refuge sooner after a simulated predator attack) and active (i.e., spent more time out of refuge) than river fish. Across populations there were positive correlations between foraging activity and both boldness and general activity;however, within populations, there was only a strong positive relationship between foraging activity and boldness in the river population. Here, we have demonstrated that populations that originate from drastically different environments can produce proge ny that exhibit measurable differences in behaviors and their correlated relati on ships eve n whe n reared un der comm on conditions.

关键词： behavioral correlation behavioral syndrome boldness hypoxia pace of life turbidity

The care and feeding of ravenously hungry girls

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The care and feeding of ravenously hungry girls

Deformation correlations,stress field switches and evolution of an orogenic intersection:The Pan-African Kaoko-Damara orogenic junction,Namibia

作者： Anissa gray.

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Geoscience Frontiers 2017年第6期8卷 1187-1232页

作者： Ben Goscombe David A.Foster David gray Ben Wade Antonios Marsellos Jason Titus Integrated Terrane Analysis Research(ITAR) 18 Cambridge RdAldgate5154SAAustralia Department of Geological Sciences University of FloridaGainesvilleFL32611USA School of earth Sciences University of TasmaniaHobartTASAustralia Adelaide Microscopy University of AdelaideAdelaide5005SAAustralia Hofstra University HempsteadNYUSA

Age calibrated deformation histories established by detailed mapping and dating of key magmatic time markers are correlated across all tectono-metamorphic provinces in the Damara Orogenic *** across structural belts result in an internally consistent deformation framework with evidence of stress field rotations with similar timing,and switches between different deformation *** principle compressive stress rotated clockwise ~180°in total during Kaoko Belt evolution,and^135° during Damara Belt *** most stages,stress field variation is progressive and can be attributed to events within the Damara Orogenic System,caused by changes in relative trajectories of the interacting Rio De La Plata,Congo,and Kalahari *** orogenesis occurred earliest and evolved from collision and obduction at ~590 Ma,involving e-W directed shortening,progressing through different transpressional states with ~45° rotation of the stress field to strike-slip shear under NW-Se shortening at ~550-530 *** orogenesis evolved from collision at ~555-550 Ma with NW-Se directed shortening in common with the Kaoko Belt,and subsequently evolved through ~90°rotation of the stress field to Ne-SW shortening at ~512-508 *** Kaoko and Damara orogenic fronts were operating at the same time,with all three cratons being coaxially convergent during the 550-530 Ma period;Rio De La Plata directed Se against the Congo Craton margin,and both together over-riding the Kalahari Craton margin also towards the *** stress field rotation was punctuated by rapid and significant switches at ~530-525 Ma,~508 Ma and ~505 *** three events included:(1)Culmination of main phase orogenesis in the Damara Belt,coinciding with maximum burial and peak metamorphism at 530-525 *** occurred at the same time as termination of transpression and initiation of transtensional reactivation of shear zones in the Kaoko *** compressive stress switched from NW-

关键词： Damara Orogen Stress fields Orogeny Assembly of Gondwana event geochronology Deformation correlations

Influence of mixed organosilane coatings with variable RGD surface densities on the adhesion and proliferation of human osteosarcoma Saos-2 cells to magnesium alloy AZ31

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Bioactive Materials 2017年第1期2卷 35-43页

作者： Xiaoxi Yang Afrah Al Hegy eric R.Gauthier Joy gray-Munro Dept.of Chemistry and Biochemistry Laurentian UniversitySudburyOntarioP3E 2C6Canada

In the last decade,the use of magnesium and its alloys as biodegradable implant materials has become increasingly ***,surface modification of these materials to control the degradation rate in the early stages of healing and improve their biocompatibility is crucial to the successful implementation of magnesium alloy implants in *** adhesion and proliferation at the implant surface is a vital factor for successful integration of a biomaterial within the *** accomplish this task by binding to ligands such as the arginine-glycine-aspartic acid peptide sequence(RGD)commonly found on adhesive proteins present in the extracellular *** this paper,we report a biomimetic surface modification strategy involving deposition of a mixed organosilane layer on Mg AZ31 followed by covalent immobilization of RGD peptides through a heterobifunctional cross-linker *** results indicate that with optimized deposition conditions uniform organosilane coatings were successfully deposited on the Mg AZ31 ***,we have demonstrated that the surface density of immobilized RGD can be varied by depositing organosilane layers from solutions containing two different organosilanes in specified *** in cell adhesion and cell proliferation were observed on the surface modified substrates.

关键词： Magnesium alloys Biodegradable Biomimetic RGD peptide Surface modification Cell adhesion Organosilane