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Clinical,biochemical and imaging characteristics of adrenal histoplasmosis in immunocompetent patients in a non-endemic area:A case series

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Asian Pacific Journal of Tropical Medicine 2021年第10期14卷 471-477页

作者： Sharmin Jahan Tahseen Mahmood md.Fariduddin Ibrahim Faisal md.Shahed Morshed Anil Yadav Anil Kumar Shah Chomon Abdullah Emran-Ur-rashid Chowdhury Ferdousi Begum MA Hasanat Department of Endocrinology Bangabandhu Sheikh Mujib Medical UniversityDhakaBangladesh Department of Endocrinology Combined Military HospitalDhaka CantonmentDhakaBangladesh Division of Endocrinology Department of Internal MedicineIndira Gandhi Memorial HospitalKanbaa Aisa Rani HigunMale'-20402Republic of Maldives Department of Emergency Kurmitola General HospitalDhakaBangladesh Division of Endocrinology Department of Internal Medicine Birat Medical College Teaching HospitalBiratnagarNepal Division of Endocrinology Department of Internal MedicineChitwan Medical CollegeChitwan 44300Nepal Department of Pathology Bangabandhu Sheikh Mujib Medical UniversityDhakaBangladesh

Objective:To document the clinical,biochemical and imaging phenotypes of immunocompetent patients with adrenal ***:The clinical,biochemical and radiologic data of 18 immunocompetent patients[age:45.00(39.25,56.25)years,median(IQR),m/f(16/2)]with adrenal histoplasmosis presenting in the Department of Endocrinology,BSMMU between 2014 and 2020 were retrospectively ***:All patients were seronegative for HIV infection,and 27.8%(5/18)had well controlled diabetes *** median duration of the symptoms was 6.00(IQR:4.00,11.25)*** had significant weight loss,anorexia and *** was present in 61.1%(11/18)patients and night sweat was present in 27.8%(5/18)*** and hyperpigmentation were present in 55.6%(10/18)and 66.7%(12/18)cases,*** of 18 patients presented with adrenal *** occurred in 55.6%(10/18)cases,but none had *** of 18 patients had adrenal insufficiency whereas 83.3%(15/18)had high adrenocorticotropic *** scan revealed bilateral adrenal enlargement in all cases with oval shape and regular *** were hypodense having radiodensity 21-90 hounsfield unit,and 11.1%(2/18)were heterogeneous in contrast *** had noticeable calcification whereas 1.1%(2/18)cases had central necrosis with peripheral rim *** was present in 6 cases,splenomegaly in 3 cases and 5 patients had abdominal *** were confirmed by positive fine needle aspiration cytology of adrenal ***:Adrenal histoplasmosis should be considered in the list of differentials of bilateral adrenomegaly in immunocompetent individuals even living in non-endemic areas.

关键词： Histoplasmosis Immunocompetent Nonendemic Adrenal CT

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Financial Vulnerability, Capital Flow Reversals, and Divergence Macro-Prudential Policies Posing Challenges to the ASEAN Banking Integration Framework （ABIF）

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Journal of Modern Accounting and Auditing 2016年第5期12卷 250-267页

作者： Mohd Yaziz Mohd Isa Yap Voon Choong David Yong Gunn Fie md. Zabid Haji Abdul rashid Universiti Tun Abdul Razak Kuala Lumpur Malaysia Multimedia University Selangor Malaysia

Against the prevailing background of an unusual capital flow reversal which is posing immense challenges to the integration of the region＇s banking sector, this study measures macro-prudential instruments affecting the implementation of an integrated financial service industry. This study is important at times when domestic and country-based financial policies are directed at competing goals. The interaction of macro-prudential policies with other policies, in particular monetary policies and micro-prudential policies is crucial to address systemic risk involved. There is growing recognition that prudential policies tools interact and coordinate with one another. To utilize multiple instruments seems to provide a greater assurance of effectiveness by tackling risk from various angles. As such, this study also assesses the interactions of the policies. The study also proposes a baseline model to capture systemic risk due to liquidity risk and risk because of currency devaluation.

关键词： capital flow reversals macro-prudential policies ASEAN Banking Integration Framework (ABIF)

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A Novel Topology of Single-Phase AC-DC Integrated Boost-SEPIC (IBS) Converter Using Common Part Sharing Method (CPSM) for High Step-Up Applications

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Journal of Power and Energy Engineering 2018年第6期6卷 38-47页

作者： Mohammad Bazlur rashid Mohammad Abdul Moin Oninda Fahim Faisal Mirza Muntasir Nishat Golam Sarowar md. Ashraful Hoque Department of Electrical and Electronic Engineering Islamic University of Technology Gazipur Bangladesh

A novel topology of Integrated Boost-SEPIC (IBS) AC-DC converter using common part sharing method (CPSM) has been proposed in this paper. Conventional boost converters with bridge rectifier configuration are inefficient due to limited voltage step-up ratio which may not be applicable for high step-up applications as in the case of micro generators. The proposed IBS topology is based on the common part sharing method capable of operating both for positive and negative half cycle of the input signal. Result and simulation were conducted using PSIM environment. The proposed AC-DC IBS topology eliminates the requirement of bridge rectifier achieving high efficiency (about 99%), improved power factor (0.75, leading) and lower THD (about 38.8%) which is within IEEE standard.

关键词： Integrated Boost-SEPIC (IBS) Bridgeless AC-DC Converter Voltage Gain THD Minimization Efficiency Improvement Power Factor Correction

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Loan Loss Reserves （LLR）, Expected Loss （EL）, and Value at Risks （VaR）

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Journal of Modern Accounting and Auditing 2015年第4期11卷 218-222页

作者： Mohd Yaziz Mohd Isa Yap Voon Choong David Yong Gun Fie md. Zabid Hj. Abdul rashid Universiti Tun Abdul Razak Kuala Lumpur Malaysia Multimedia University Selangor Malaysia

This paper clarifies the distinctions between loan loss reserves （LLR）, expected loss （EL）, and loan loss provisions （LLP）. The paper also includes information on individual and collective impairment assessment of local commercial banks in Malaysia collected from their annual reports. Most banks have maintained collective assessment （CA） allowance ratio of lower than 1.2% of gross total loans.

关键词： collective assessment (CA) loan loss reserves (LLR) value at risk (VaR)

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Effect of Tillage and Residue Retention on Soil Properties and Crop Yields in Wheat-Mungbean-Rice Crop Rotation under Subtropical Humid Climate

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Open Journal of Soil Science 2017年第1期7卷 1-17页

作者： Nazmus Salahin Khairul Alam Abu Taher Mohammad Anwarul Islam Mondol Mahammad Shariful Islam md. harunur rashid Muhammad Azizal Hoque Soil Science Division Bangladesh Agricultural Research Institute (BARI) Gazipur Bangladesh Land Management Group School of Veterinary and Life Sciences Murdoch University Murdoch Australia On-Farm Research Division BARI Gazipur Bangladesh Department of Agricultural Extension MoA Dhaka Bangladesh

The effects of conservation agriculture (CA) practices on soil properties along with crop yields of rice-based triple cropping systems have not been adequately assessed in Bangladesh. An experiment was conducted at Bangladesh Agricultural Research Institute, Gazipur, Bangladesh from 2009 to 2012 to assess the effects of tillage practices and crop residue retention on soil physical properties, soil organic carbon (SOC) and crop yields in a wheat-mungbean-rice system. Treatments consisted of three tillage practices (MT: minimum tillage;CT: conventional tillage and DT: deep tillage) and eight levels of crop residue management (S0—no residues retention, Sr—retention of 30 cm rice straw, Sm—whole mungbean stover retention, SW—30 cm wheat straw retention, Smr—whole mungbean stover & 30 cm rice straw retention, Srw—30 cm rice & wheat straw retention, Smw—whole mungbean stover & 30 cm wheat straw retention and Swrm—30 cm wheat and rice straw along with whole mungbean stover retention) were applied in split plot design with three replications. Bulk density (BD) and porosity responded positively to MT and increased residue retention of all crops (p > 0.05). Minimum tillage and Swrm also significantly accumulated SOC (p < 0.05;0.38% higher than DT with no residue retention) and retained soil moisture (p < 0.05). Minimum tillage practice performed better in upland crops (p < 0.05;wheat & mungbean yields) and CT outperformed MT in wetland rice crop (p < 0.05). The grain and straw yields of wheat and rice were also influenced by previous crop residue retentions (p < 0.05). The results, therefore, suggested that increased residue retention with minimum tillage practices improved soil properties and yield of upland crops but with deeper tillage practices consistently maintained wetland rice production.

关键词： Cropping System Residue Retention Soil Moisture Soil Organic Carbon (SOC) Tillage Practices

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Feminist Literary Criticism: A Paradigm of Matriarchy inLiterature

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Journal of Literature and Art Studies 2020年第2期10卷 93-97页

作者： md.Masud Rana Amina rashid Jazan University JazanSaudi Arabia

Feminist literary theory underpins literature from matriarchal perspective revolting against prototype patriarchal ritual *** dogmatism,superstition,close-eyed religious propaganda,language engineering and so *** questions the textual politics of dissipating womankind in *** shatters long-cherishing outlook of gender inequality,gender politics,power relation,sexual objectification,oppression,patriarchy,stereotyping and so *** this connection,this theory sees women along with their experiences,thinking,language,position and role playing,cultural conditioning,diction,and above all,matriarchal assertion in *** literary criticism has been generated from feminism and the basic aim of the theory is to investigate and trace out how female characters have been positioned in literature compared with male characters in terms of social and biological factors of different ages of the past started from *** literary theory has also deconstructed texts from two different perspectives *** written by men and text written by *** paper attempts to evalualte feminist literary criticism as a subtle machinery or paradigm of matriarchy not only in avant-garde but also in old texts of literature.

关键词： Avant-garde feminist literary criticism feminism matriarchy patriarchy androtexts gynotexts psychoanalysis ecrrture feminine

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Antidiabetic Drugs in Combination with Hydroxychloroquine Improve Glycemic Control in Alloxan Induced Diabetic Rats

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Pharmacology & Pharmacy 2014年第7期5卷 725-735页

作者： Shaheda Zannah md. Saiful Islam A. F. M. Towheedur Rahman md. Asaduzzaman Abdul Alim Al Bari Yusuf Ali Gazi Jahirul Islam A. H. M. Khurshid Alam Hazrat Ali Mamunur rashid Department of Chemistry Khulna University of Engineering and Technology Khulna Bangladesh Department of Pharmacy University of Rajshahi Rajshahi Bangladesh

Worldwide prevalence of diabetes mellitus has become an issue of great concern in current decades. This life threatening disease is associated with worsening of glycemic control and progressive metabolic dysfunctions. Objective: Current study aimed to investigate the effect of hydroxychloroquine (HCQ) as an adjunct to glibenclamide or metformin on glycemic control in alloxan induced diabetic rats. Methods: HCQ was combined separately with two conventional anti-diabetic drugs;glibenclamide and metformin. At first, alloxan (120 mg/kg) induced diabetic rats were treated with single dose of metformin (850 mg/70 kg BW), glibenclamide (10 mg/70 kg BW) and HCQ (300 mg/70 kg BW) intraperitoneally once daily for two weeks. Then non fixed dose combinations of glibenclamide (5 mg/70 kg BW) with HCQ (150 mg/70 kg BW) and metformin (425 mg/70 kg BW) with HCQ (150 mg/70 kg BW) were injected along with those of the three drugs alone once daily for four weeks. Results: In alloxan induced diabetic rats, glibenclamide, metformin and their combination therapies reduced blood glucose level significantly but combination therapies are the most effective. Glibenclamide or metformin in combination with HCQ also significantly (P < 0.05) reduced the elevated levels of total cholesterol, triglycerides, and low density lipoprotein cholesterol (LDL-C) level and increased high density lipoprotein cholesterol (HDL-C) level. Moreover, HCQ potentiates the liver glycogen synthesis of metformin or glibenclamide. Conclusion: Outcomes of this investigation indicate that combination of glibenclamide or metformin with HCQ improves glycemic control and provides additional metabolic benefits, not achieved with either glibenclamide or metformin alone.

关键词： Diabetes Mellitus Glycemic Control HCQ Glibenclamide Metformin

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Incidence, Risk Factors and Short Term Outcome of Acute Kidney Injury among Patients with Acute Coronary Syndrome

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Journal of Biosciences and Medicines 2020年第5期8卷 177-188页

作者： md. Kabir Hossain Muhammad Rafiqul Alam Asia Khanam A. K. M. Shahidur Rahman Rafi Nazrul Islam Syed Fazlul Islam Mohammad Kamrul Ahsan S. K. Mamun-Ar-rashid Tanvir Rahman md. Nazmul Hasan Department of Nephrology Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka Bangladesh Department of Nephrology & Dialysis BIRDEM General Hospital Dhaka Bangladesh Holy Family Red Crescent Medical College Hospital (HFRCMCH) Dhaka Bangladesh Department of Medicine Khulna Medical College Hospital Khulna Bangladesh Department of Nephrology United Hospital Limited Dhaka Bangladesh Department of Cardiology Ad-din Medical College Hospital Dhaka Bangladesh

Background: Cardio-renal syndrome is the leading cause of death globally. Acute kidney injury (AKI) is a major complication among patients admitted in Coronary Care Unit (CCU) with acute coronary syndrome (ACS). AKI in ACS patients is associated with higher morbidity, mortality and prolong hospital stay. Objective: To determine the incidence, risk factors and short term outcome of acute kidney injury (AKI) among the patients admitted in CCU with ACS. Methods: This cross sectional study was conducted at Department of Nephrology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from January 2013 to December 2013. Following selection criteria a total of two hundred (200) patients with ACS were studied. AKI was defined according to the KDIGO guideline and further categorized by RIFLE criteria. Data of patients with AKI and those without AKI were analyzed and compared by statistical tests. Results: Majority of the study patients were male (79.5%). AKI was developed in 40 of the 200 study patients (20.0%). The mean (±SD) age of the study patients was 60.1 ± 11.1 years in patients with AKI and 55.9 ± 10.1 years in patients without AKI. Our data analysis showed that older age (>65 years), diabetes mellitus, dyslipidemia and smoking were significantly correlated to the development of AKI. Mortality was significantly high in AKI group (7.15%) compared to no AKI group (1.25%). Out of 27 patients who achieved renal recovery most (80.8%) belonged to risk class. Severity of AKI showed significant effect on renal recovery and final outcome. Conclusion: This study demonstrated that, incidence of AKI among patients with ACS was 20%. Elderly patients, diabetes mellitus, dyslipidemia, and exposure to smoking were significantly associated with development of AKI in ACS.

关键词： Acute Kidney Injury (AKI) Acute Coronary Syndrome (ACS) Cardio-Renal Syndrome

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POM analysis and computational interactions of 8-hydroxydiospyrin inside active site of protein tyrosine phosphatase 1B

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BIOCELL 2021年第3期45卷 751-759页

作者： SAUD BAWAZER ASGHAR KHAN ABDUR RAUF TAIBI B EN HADDA YAHYA SAL-AWTHAN OMAR BAHATTAB UMER rashid INAMULLAH KHAN MUHAMMAD A SIF NAWAZ md.SAHAB UDDIN OLATUNDE AHMED MOHAMMAD A LI SHARIATI Department of Pharmaceutical Chemistry Faculty of PharmacyUmm Al-Qura UniversityMakkah21955Saudi Arabia Department of Medicine Khyber Teaching Hospital Peshawar25000Pakistan Department of Chemistry University of SwabiSwabi23430Pakistan LCM Laboratory Mohammed First UniversityFaculty of SciencesOujda60000Morocco Biology Department Faculty of SciencesUniversity of TabukTabuk1144Saudi Arabia Department of Biology Faculty of ScienceIbb UniversityIbbYemen Department of Chemistry COMSATS University IslamabadAbbottabad CampusAbbottabad22060Pakistan Department of Pharmacy University of PeshawarPeshawar25120Pakistan Department of Biotechnology Shaheed Benazir Bhutto UniversitySheringal14400Pakistan Department of Pharmacy Southeast UniversityDhaka1213Bangladesh Pharmakon Neuroscience Research Network Dhaka1207Bangladesh Department of Biochemistry Abubakar Tafawa Balewa UniversityBauchi740272Nigeria Moscow State University of Technologies and Management(The First Cossack University) Moscow119991Russian Federation

Proteintyrosine phosphatase 1B(PTP1B)inhibitionis consideredas a potentialtherapeuticfor the treatmentof cancer,type2 diabetes,*** presentwork,weinvestigatedtheanti-diabeticpotentialof8-hydroxydiospyrin(8-HDN)from *** against the PTP1B *** showed significant inhibitory activity of PTP1B with an IC 50 value of 18.37±0.02μM.A detailed molecular docking study was carried out to analyze the binding orientation,binding energy,and mechanism of inhibition.A comparative investigation of 8-HDN in the catalytic,as well as the allosteric site of PTP1B,was *** energy data showed that compound 8-HDN is more selective for the allosteric site and hence avoids the problems associated with catalytic site *** inhibition mechanism of 8-HDN can be further investigated as an active lead compound against PTP1B by using in vitro and in vivo models.

关键词： Diospyros lotus Roots 8-Hydroxydiospyrin Molecular docking Protein tyrosine phosphatase 1B

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Frequency of Malignancy in Solitary Thyroid Nodule in a Tertiary Level Hospital of Bangladesh

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International Journal of Otolaryngology and Head & Neck Surgery 2019年第4期8卷 132-138页

作者： md.Shazibur rashid Najnin Akhter md.Shafiqur Rahman Jahangir Alam Majumd.r A. H. M. Delwar md.Golam Mustafa Otolaryngology Comilla Medical College Cumilla Bangladesh Pediatrics Comilla Medical College Cumilla Bangladesh

Objectives: To determine the frequency of thyroid malignancy in clinically and sonographically solitary thyroid nodule in patients undergoing thyroidectomy in Comilla Medical College Hospital. Methods: A cross sectional study was carried out at the Department of Otolaryngology and Head Neck Surgery of Comilla Medical College Hospital during the period from January 2016 to January 2019. This study includes all patients admitted and undergoing surgery with solitary thyroid nodule. Results: Out of 188 patients 146 patients were female and 42 patients were male with female:male ratio of 3.4:1. Out of 188 patients 24 patients were found histologically thyroid malignancy. Among them 14 patients were male and 10 patients were female. Papillary carcinoma was found in all cases. Conclusions: Follicular carcinoma is rare in our country. Histopathological examiners may not efficiently be doing their job to differentiate carcinoma from adenoma.

关键词： Solitary Thyroid Nodule Papillary Carcinoma Follicular Carcinoma

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