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Reproductive health and rights in the COVID-19 era:Why and how are rights and choices still the answer?

Asian pacific Journal of Reproduction 2022年第4期11卷 155-157页

作者： md anwer hossain Department of Population Sciences Faculty of Social SciencesUniversity of DhakaDhaka-1000Bangladesh

Amidst the coronavirus disease 2019(COVID-19)pandemic,the concern over the potential‘baby boom’or‘baby bust’had drawn renewed attention across the globe[1-3].However,historically alarmism over fertility rates gave rise to restrictive and coercive policies with an aim of‘controlling the population’that violated people’s sexual and reproductive health and rights(SRHR).In this perspective,the author argued that whether countries of the world face a COVID-19-induced short-term baby boom or bust,the solution lies in prioritizing the rights and choices of all people,especially their SRHR;not in adopting target-oriented population policies or coercive family planning programs.

关键词： priori fertility choice

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Measurement and correlation of solubility of diosmin in four pure solvents and β-cyclodextrin solution at 298.15K to 333.15K

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Chinese Journal of Chemical Engineering 2015年第5期23卷 812-815页

作者： md Khalid anwer Faiyaz Shakeel Department of Pharmaceutics College of Pharmacy Salman Bin Abdulaziz University Center of Excellence in Biotechnology Research King Saud University Department of Pharmaceutics College of Pharmacy King Saud University

The aim of present study was to measure and correlate the solubility of poorly water-soluble flavonoid diosmin in water, ethanol, isopropyl alcohol （IPA）, polyethylene glycol-400 （PEG-400） and β-cyclodextrin （β-CD） aqueous solution （0.02 mol·L^-1 ）. The solubility of diosmio was measured using the shake flask method from （298.15 to 333.15） K at atmospheric pressure. The experimental solubilities of diosmin were regressed by the modified Apelblat model with a relative deviation in the range of 0.048% to 5.940%. The correlation coefficients were observed in the range of 0.9957 to 0.9995. The solubility of diosmin was found to be increased with temperature in all sample matrices investigated. The mole fraction solubility of diosmin was found to be higher in 5-CD aqueous solution and PEG-400 as compared to water, ethanol and IPA. Based on solubility data of present study, diosmin was considered as practically insoluble in water, insoluble in ethanol ＆ IPA and soluble in PEG- 400 and β-CD aqueous solution.

关键词： Apelblat model Cyclodextrin Diosmin Solubility Thermodynamics

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An Automated Deep Learning Based Muscular Dystrophy Detection and Classification Model

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Computers, Materials & Continua 2022年第4期71卷 305-320页

作者： T.Gopalakrishnan Periakaruppan Sudhakaran K.C.Ramya K.Sathesh Kumar Fahd N.Al-Wesabi Manal Abdullah Alohali anwer Mustafa Hilal School of Computer Science and Engineering Vellore Institute of TechnologyVellore632014India Department of Computer Science and Engineering SRM TRP Engineering CollegeTiruchirappalli621105India Department of Electrical and Electronics Engineering Sri Krishna College of Engineering and TechnologyCoimbatore641008India School of Computing Kalasalingam Academy of Research and EducationKrishnankoil626128India Department of Computer Science King Khalid UniversityMuhayel AseerKSA Faculty of Computer and IT Sana’a UniversityYemen Department of Information Systems College of Computer and Information SciencesPrincess Nourah Bint Abdulrahman UniversitySaudi Arabia Department of Computer and Self Development Preparatory Year DeanshipPrince Sattam bin Abdulaziz UniversityAlkharjSaudi Arabia

Muscular Dystrophy (md) is a group of inherited muscular diseases that are commonly diagnosed with the help of techniques such asmuscle biopsy, clinical presentation, and Muscle Magnetic Resonance Imaging(MRI). Among these techniques, Muscle MRI recommends the diagnosis ofmuscular dystrophy through identification of the patterns that exist in musclefatty replacement. But the patterns overlap among various diseases whereasthere is a lack of knowledge prevalent with regards to disease-specific ***, artificial intelligence techniques can be used in the diagnosis ofmuscular dystrophies, which enables us to analyze, learn, and predict forthe future. In this scenario, the current research article presents an automated muscular dystrophy detection and classification model using SynergicDeep Learning (SDL) method with extreme Gradient Boosting (XGBoost),called SDL-XGBoost. SDL-XGBoost model has been proposed to act as anautomated deep learning (DL) model that examines the muscle MRI dataand diagnose muscular dystrophies. SDL-XGBoost model employs Kapur’sentropy based Region of Interest (RoI) for detection purposes. Besides, SDLbased feature extraction process is applied to derive a useful set of featurevectors. Finally, XGBoost model is employed as a classification approach todetermine proper class labels for muscle MRI data. The researcher conductedextensive set of simulations to showcase the superior performance of SDLXGBoost model. The obtained experimental values highlighted the supremacyof SDL-XGBoost model over other methods in terms of high accuracy being96.18% and 94.25% classification performance upon Dmd and Bmd respectively. Therefore, SDL-XGBoost model can help physicians in the diagnosis of muscular dystrophies by identifying the patterns of muscle fatty replacementin muscle MRI.

关键词： Muscle magnetic resonance imaging XGBoost synergic deep learning roI detection kapur’s entropy muscular dystrophies

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喜来芝石中提取的腐植酸与阿司匹林的分子络合物及其表征

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腐植酸 2010年第4期 34-39页

作者： md.Khalid anwer Suraj P.Agarwal Asgar Ali Yasmin Sultana 黄静佳米雅综合大学药剂学院南德里110062 中国腐植酸工业协会北京100120

阿司匹林具有退热、消炎、止痛和抗血小板凝集的作用。乙酰水杨酸分子含一个羧基和一个酯基。酯基容易被水解,导致其药效降低,并会对人体产生副作用。本研究的目的是用冻干技术和溶剂挥发技术,以原料的物质的量比为1∶1和1∶2,制备阿司... 详细信息

阿司匹林具有退热、消炎、止痛和抗血小板凝集的作用。乙酰水杨酸分子含一个羧基和一个酯基。酯基容易被水解,导致其药效降低,并会对人体产生副作用。本研究的目的是用冻干技术和溶剂挥发技术,以原料的物质的量比为1∶1和1∶2,制备阿司匹林和腐植酸固态络合物。阿司匹林和腐植酸分子间相互作用通过差示扫描量热法(DSC)、X射线衍射(XRD)、傅里叶变换红外光谱学法(FT-IR)和扫描电子显微镜法(SEM)进行研究。用这些技术能清晰表明固态包合络合物的结构。对物质的量比为1∶2冻干络合物研究表明,阿司匹林的稳定性和溶出率显著提高。优选的冻干阿司匹林与腐植酸(1∶2)络合物对抑制鼠爪水肿和抗溃疡作用测得的最低值(0.63±0.10)与单纯的阿司匹林相比,有明显的降低,证明用其治疗具有非常显著的抗炎作用(P<0.05)。

关键词：阿司匹林喜来芝石腐植酸表征稳定性生物药效率

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喜来芝石中提取的腐植酸与阿司匹林的分子络合物及其表征

喜来芝石中提取的腐植酸与阿司匹林的分子络合物及其表征

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第八届全国绿色环保肥料（农药）新技术、新产品交流会

作者： md.Khalid anwer Suraj P.Agarwal Asgar Ali Yasmin Sultana 黄静佳米雅综合大学药剂学院中国腐植酸工业协会

阿司匹林具有退热、消炎和抗血小板凝集的作用。乙酰水杨酸分子含一个羧基和一个酯基。酯基容易被水解,导致其药效降低,并会对人体产生副作用。本研究的目的是用冻干技术和溶剂挥发技术,以原料的摩尔比为1:1和1:2,制备阿司匹林和腐植酸... 详细信息

阿司匹林具有退热、消炎和抗血小板凝集的作用。乙酰水杨酸分子含一个羧基和一个酯基。酯基容易被水解,导致其药效降低,并会对人体产生副作用。本研究的目的是用冻干技术和溶剂挥发技术,以原料的摩尔比为1:1和1:2,制备阿司匹林和腐植酸固态配合物。阿司匹林和腐植酸分子间相互作用通过差示扫描量热法(DSC)、X射线衍射(XRD)和扫描电子显微镜(SEM)法进行研究。用这些技术能清晰表明固态包内配合物的结构。对摩尔比为1:2冻干配合物研究表明阿司匹林的稳定性和溶出率显著提高。优选的冻干阿司匹林与腐植酸(1:2)配合物对抑制鼠爪水肿和抗溃疡作用测得的最低值(0.63±0.10)与单纯的阿司匹林相比,有明显的降低,证明用其治疗具有非常显著的抗炎作用(p<0.05)。

关键词：阿司匹林喜来芝石腐植酸表征稳定性生物利用度

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Fosfomycin—A Promising Oral Antibiotic for the Treatment of Urinary Tract Infection (UTI)

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Open Journal of Urology 2022年第5期12卷 257-270页

作者： Sadia Sharmin Sheikh Mohammed Mostofa Kamal md. Alimur Reza Khandokar Mohammad Ashik Elahi Sheikh Mohammed Mostofa Elma Bushra Habib Department of Microbiology Anwer Khan Modern Medical College Hospital Dhaka Bangladesh Department of Medical Affairs Beximco Pharmaceuticals Limited Dhaka Bangladesh Department of Pharmacology Anwer Khan Modern Medical College Hospital Dhaka Bangladesh

Background: Among the common morbid causes that are prevalent among all age groups, urinary tract infections top the list. In our country, most of the UTI patients visiting hospitals (OPD or IPD) are already on empirical antibiotics even before getting the sensitivity report in their hand. The purpose of this research was to examine the susceptibility patterns of commonly used antibiotics, particularly fosfomycin, against common uropathogens. Methodology: This was a prospective observational study conducted between January and March 2021 in four private tertiary hospitals in Dhaka, Bangladesh. All the urine samples referred to these four laboratories, obtained from patients of all ages and both genders, clinically diagnosed to have UTI, were included. Urine culture was performed by a semiquantitative method on blood agar media and MacConkey agar media. Following identification, antimicrobial sensitivity testing was performed using the modified Kirby Bauer disk diffusion method in accordance with CLSI standards. The data was put into Statistical Package for Social Sciences (SPSS) statistical software version 25 for the analysis. Results: A total of 5389 urine samples were received from four private hospitals in Dhaka over three months, and of these, 934 (17.33%) isolates were obtained from culture. About 95% of the isolates were gram-negative bacilli (GNBs). The most common isolate was Escherichia coli 615 (65.85%), followed by Klebsiella spp. 154 (16.49%), Pseudomonas spp. 64 (6.85%) and 51 (5.46%) isolates of Enterobacter. Among the gram-positive cocci, the most common were Enterococci fecalis 18 (1.93%) and Staphylococcus aureus 17 (1.82%). Of all the antibiotics tested, fosfomycin sensitivity was 98.4%, 88.88%, and 100% for Escherichia coli, Enterococci fecalis, and Staphylococcus aureus, respectively. All the isolates tested were susceptible to Meropenem (77% - 100%), Amoxiclav (78% - 100%) and Nitrofurantoin (45% - 94%). Sensitivity amongst all the uropathogens

关键词： Antibiotic Susceptibility Fosfomycin Urinary Tract Infections

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