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Brain abscess:surgical experiences of 162 cases

Neuroimmunology and Neuroinflammation 2015年第1期2卷 153-161页

作者： Forhad Hossain Chowdhury md raziul haque Mainul haque Sarkar S.M.Noman Khaled Chowdhury Zahed Hossain Shisir Ranjan Department of Neurosurgery National Institute of Neurosciences and HospitalSher-e-Bangla NagarDhaka 1207Bangladesh Department of Neurosurgery Dhaka Medical CollegeDhaka 1000Bangladesh Department of Neonatolgy Dhaka Medical CollegeDhaka 1000Bangladesh

Aim:Brain abscess still poses a public health challenge in spite of the advent of modern neurosurgical techniques and ***,we present our surgical experiences and ultimate outcome in the management of brain ***:Totally,162 patients with proved brain abscess who underwent surgical treatment were included in this *** prospectively recorded data of surgical management of brain abscess and the ultimate outcome(by Glasgow outcome scale)were studied ***:Total number of cases was 162,of which 113 were acute pyogenic abscess while 49 were chronic *** the chronic abscess,29 were chronic pyogenic abscess,14 were tubercular,3 aspergillus,and 3 abscesses were in malignant brain *** acute cases,common clinical features were headache,fever,vomiting,focal deficit and *** chronic abscesses,common clinical features were mild to moderate headache and progressive focal ***-three(45.06%)patients had adjacent localized sinus,middle ear or cranial *** common predisposing factors included postneurosurgery,postpenetrating injury to brain,chronic suppurative otitis media,and congenital heart disease,infective endocarditis,sinusitis and sub optimum *** lobe involved in 30.2%cases,temporal lobe is next to *** time burr hole aspiration in 111(68.5%)cases,two or more times burr hole aspiration were done in 34(21%)*** culture was negative in 129(79.62%)*** number of death was 22(13.58%)*** resolution of abscess with complete recovery of preoperative neuro-deficit was seen in 80.86%cases and recovery with major neuro-deficit was observed in 5.55%*** is a significant association between Glasgow coma scale(GCS)on admission and mortality in brain ***:In most of the cases,pus culture did not yield growth of any causative *** was not directly related to surgical intervention,but GCS on admission has a significant

关键词： Acute and chronic brain abscess brain abscess outcome surgical management

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Bibliographic survey and comprehensive review on mechanical and durability properties of microorganism based self-healing concrete

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Frontiers of Structural and Civil Engineering 2024年第9期18卷 1445-1465页

作者： md Marghoobul haque Kunal M.SHELOTE Namrata SINGH Supratic GUPTA Department of Civil Engineering Indian Institute of Technology DelhiNew Delhi 110016India

Concrete is the most widely utilized material for construction purposes,second only to water,in the ever-increasing need for construction *** is a brittle material and possesses a high risk of crack formation and consequent ***,which allows chemicals to enter and can cause concrete structures to lose their physico-mechanical and durability *** and rehabilitating concrete structures involves high costs and leads to various repair methods including coating,adhesives,polymers,supplementary cementitious materials(SCMs),and *** of the latest technologies is the use of microorganisms in *** added microorganisms lead to calcite precipitation and thereby heal the cracks *** study presents a comprehensive literature survey on bacteria-included concrete,before which a bibliographic survey is performed using VOSViewer *** addition to regular bacterial concrete,this study focuses on also using SCMs and fibers in bacterial concrete.A detailed literature review with data representation for various mechanical properties including compressive strength(CS),split tensile strength(SS),and flexure strength(FS),along with durability properties including carbonation,water absorption,resistance against chloride ion penetration,gas permeation,and resistance against cyclic freeze-and-thaw is presented.A study on the use of X-ray computed tomography(XCT)in bacterial concrete is highlighted,and the scope for future research,along with identification of the research gap,is presented.

关键词： bacterial concrete bibliographic survey biomineralization carbonation fibers

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Ionotropic receptors mediate olfactory learning and memory in Drosophila

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Insect Science 2024年第4期31卷 1249-1269页

作者： md Zeeshan Ali Anushree Aarif Ahsan Mohammad Shamsul Ola Rizwanul haque Jawaid Ahsan Department of Biotechnology Central University of South BiharGayaBiharIndia Department of Radiation Oncology University of MichiganAnn ArborMichiganUSA Department of Biochemistry College of ScienceKing Saud UniversityRiyadhSaudi Arabia

Phenylacetaldehyde(PAH),an aromatic compound,is present in a diverse range of fruits including overripe bananas and prickly pear cactus,the two major host fruits for Drosophila *** acts as a potent ligand for the ionotropic receptor 84a(IR84a)in the adult fruit fly and it is detected by the IR84a/IR8a heterotetrameric *** role in the male courtship behavior through IR84a as an environmental aphrodisiac is of additional *** ***,two distinct kinds of olfactory receptors,that is,odorant receptors(ORs)and ionotropic receptors(IRs),perceive the odorant *** display unique structural,molecular,and functional characteristics in addition to having different evolutionary ***,olfactory cues detected by the ORs such as ethyl acetate,1-butanol,isoamyl acetate,1-octanol,4-methylcyclohexanol,*** as aliphatic esters and alcohols have been employed in olfactory classical conditioning using fruit *** underlines the participation of OR-activated olfactory pathways in learning and memory *** study elucidates that likewise ethyl acetate(EA)(an OR-responsive odorant),PAH(an IR-responsive aromatic compound)too can form learning and memory when associated with an appetitive gustatory *** association of PAH with sucrose(PAH/SUC)led to learning and formation of the long-term memory(LTM).Additionally,the Orco^(1),Ir84a^(MI00501),and Ir8a^(1)mutant flies were used to confirm the exclusive participation of the IR84a/IR8a complex in PAH/SUC olfactory associative *** results highlight the involvement of IRs via an IR-activated pathway in facilitating robust olfactory behavior.

关键词： appetitive conditioning Drosophila melanogaster ethyl acetate ionotropic receptors learning and memory phenylacetaldehyde

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An integrated framework for assessing renewable-energy supply chains using multicriteria decision-making:a study on Bangladesh

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Clean Energy 2024年第3期8卷 1-19页

作者： A.M.Almas Shahriyar Azad Zarin Tasnim Oishi md.Ariful haque Pronob Das Sabbir Ahmed Udoy Khaled Mohammad Shifullah Bhuiya Department of Industrial&Production Engineering Rajshahi University of Engineering&TechnologyRajshahi-6204Bangladesh Department of Mechanical Engineering Rajshahi University of Engineering&TechnologyRajshahi-6204Bangladesh

The depletion in non-renewable energy sources and a fast-growing population in Bangladesh are exacerbating the already existing energy scarcity,highlighting the need for an efficient and robust renewable-energy supply *** primary goal of this study is to evaluate the most optimized renewable-energy supply chain based on natural resource availability and government policies of *** the present study,four renewable energy resources,including solar,biomass,wind and hydropower,are studied and nine subcriteria are defined under four primary criteria for each supply *** for Order Preference by Similarity to Ideal Solution(TOPSIS)and VIseKriterijumska Optimizacija I Kompromisno Resenje(VIKOR)are multicriteria decision-making approaches used in this study to compare and choose the best renewable-energy supply *** relative significance of four supply-chain criteria for primary renewable energy in this study,namely energy procurement,production,operations and maintenance costs,and social and environmental impact,is gathered via a *** results of this research,supported by a comprehensive sensitivity analysis,indicate that hydropower is the best renewable-energy supply chain,followed by wind as a compromise solution,biomass and *** study also demonstrates that no energy source can satisfy all supply-chain criteria alone;each resource is better for a specific criterion-solar is better for procurement,hydropower is significant for production and wind is remarkable for operations and social ***,to maximize output,renewable energy sources must be *** Bangladesh’s perspective,for the first time,by using TOPSIS and VIKOR together,this study offers significant insights to establish an efficient and sustainable renewable-energy supply chain for practitioners,academics and policymakers.

关键词： renewable-energy supply chain Bangladesh multicriteria decision-making TOPSIS(Technique for Order Preference by Similarity to Ideal Solution) VIKOR(VIseKriterijumska Optimizacija I Kompromisno Resenje)

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A Novel LSB Steganography Technique for Enhancing Cloud Security

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Journal of Information Security 2024年第3期15卷 355-377页

作者： Ahsan Ullah md. Inzamul haque md. Mokarom Hossain md. Sadman Ahammad Mst. Nishita Aktar Department of Computer Science and Engineering World University of Bangladesh Dhaka Bangladesh

Steganography is a technique that is frequently used to hide hidden information in multimedia artifacts including music, video, and images. In order to protect data saved in the cloud, this paper presents a steganography method for encrypting sound utilizing LSB-based computation. By using the least significant bit (LSB) of a byte to represent a message and then substituting each LSB bit with a binary message and encrypting a significant quantity of data. The proposed system uses the LSB technique of picture steganography, Multi-Level Encryption Algorithm (MLEA) and Two-Level Encryption Algorithm (TLEA) data encryption to give the highest level of cloud security. Compared to other current schemes, the performance of the suggested method is 1.732125% better on average.

关键词： Steganography LSB Cloud Computing Security Cryptography TLEA MLEA

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The link between intracellular calcium signaling and exosomal PD-L1 in cancer progression and immunotherapy

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Genes & Diseases 2024年第1期11卷 321-334页

作者： md Rakibul Alam md Mizanur Rahman Zhiguo Li Department of Toxicology and Cancer Biology College of MedicineUniversity of KentuckyLexingtonKY 40506USA Department of Medicine(Nephrology) Faculty of Medicine and DentistryUniversity of AlbertaEdmontonAlberta T6E2H7Canada

Exosomes are small membrane vesicles containing microRNA,RNA,DNA fragments,and proteins that are transferred from donor cells to recipient *** cells release exo-somes to reprogram the factors associated with the tumor microenvironment(TME)causing tu-mor metastasis and immune *** evidence revealed that cancer cell-derived exosomes carry immune inhibitory molecule program death ligand 1(PD-L1)that binds with re-ceptor program death protein 1(PD-1)and promote tumor progression by escaping immune ***,some FDA-approved monoclonal antibodies are clinicallyused for cancer treatment by blocking PD-1/PD-L1 *** notable treatment outcomes,some pa-tients show poor drug *** PD-L1 plays a vital role in lowering the treatment response,showing resistance to PD-1/PD-L1 blockage therapy through recapitulating the ef-fect of cell surface *** enhance therapeutic response,inhibition of exosomal PD-L1 is *** signaling is the central regulator of tumorigenesis and can regulate exosome biogenesis and secretion by modulating Rab GTPase family and membrane fusion ***-mune checkpoints are also connected with calcium signaling and calcium channel blockers like amlodipine,nifedipine,lercanidipine,diltiazem,and verapamil were also reported to suppress cellular PD-L1 ***,to enhance the PD-1/PD-L1 blockage therapy response,the reduction of exosomal PD-L1 secretion from cancer cells is in our therapeutic *** this review,we proposed a therapeutic strategy by targeting calcium signaling to inhibit the expression of PD-L1-containing exosome levels that could reduce the anti-PD-1/PD-L1 therapy resistance and increase the patient's drug response rate.

关键词： Calcium signaling CD8^(+)T cells Exosomal PD-L1 Exosomes biogenesis Immunosuppression Immunotherapy

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Numerical Study and Optimization of CZTS-Based Thin-Film Solar Cell Structure with Different Novel Buffer-Layer Materials Using SCAPS-1D Software

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Energy and Power Engineering 2024年第4期16卷 179-195页

作者： md. Zamil Sultan Arman Shahriar Rony Tota md. Nuralam Howlader Hasibul haque Rodro Mahfuja Jannat Akhy md. Abir Al Rashik Department of Electrical and Electronic Engineering Hajee Mohammad Danesh Science and Technology University Dinajpur Bangladesh

This study explored the performances of CZTS-based thin-film solar cell with three novel buffer layer materials ZnS, CdS, and CdZnS, as well as with variation in thickness of buffer and absorber-layer, doping concentrations of absorber-layer material and operating temperature. Our aims focused to identify the most optimal thin-film solar cell structure that offers high efficiency and lower toxicity which are desirable for sustainable and eco-friendly energy sources globally. SCAPS-1D, widely used software for modeling and simulating solar cells, has been used and solar cell fundamental performance parameters such as open-circuited voltage (), short-circuited current density (), fill-factor() and efficiency() have been optimized in this study. Based on our simulation results, it was found that CZTS solar cell with Cd0.4Zn0.6S as buffer-layer offers the most optimal combination of high efficiency and lower toxicity in comparison to other structure investigated in our study. Although the efficiency of Cd0.4Zn0.6S, ZnS and CdS are comparable, Cd0.4Zn0.6S is preferable to use as buffer-layer for its non-toxic property. In addition, evaluation of performance as a function of buffer-layer thickness for Cd0.4Zn0.6S, ZnS and CdS showed that optimum buffer-layer thickness for Cd0.4Zn0.6S was in the range from 50 to 150nm while ZnS offered only 50 – 75 nm. Furthermore, the temperature dependence performance parameters evaluation revealed that it is better to operate solar cell at temperature 290K for stable operation with optimum performances. This study would provide valuable insights into design and optimization of nanotechnology-based solar energy technology for minimizing global energy crisis and developing eco-friendly energy sources sustainable and simultaneously.

关键词： Thin-Film Solar Cell CZTS Buffer-Layer Renewable Energy Green-House Gases Efficiency

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Synergistic enhancement of photocatalytic and antimicrobial efficacy of nitrogen and erbium co-doped ZnO nanoparticles

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Journal of Rare Earths 2024年第5期42卷 859-868,I0002页

作者： Sudipta Mondal Moniruzzaman Jamal Sikder Ashikuzzaman Ayon md Jannatul Ferdous Anik md Muktadir Billah Department of Materials and Metallurgical Engineering Bangladesh University of Engineering and TechnologyDhaka1000Bangladesh School of Materials Engineering Purdue UniversityWest LafayetteIN47907USA Department of Materials Science and Engineering University of CaliforniaBerkeleyCA94720USA Department of Materials Science and Engineering Northwestern UniversityEvanstonI28USA

Using the chemical co-precipitation approach,a series of nitrogen(N) and erbium(Er) co-doped ZnO nanoparticles(NPs) was effectively synthesized to enhance the photocatalytic and antibacterial *** characterization techniques,including X-ray diffraction(XRD),X-ray photoelectron spectro scopy(XPS),scanning electron microscopy(SEM),UV-vis,and photoluminescence(PL) spectroscopy,were carried out to validate the evaluated photocatalytic and antibacterial *** analysis confirms the pure wurtzite ZnO phase without the presence of any secondary *** analysis confirms the succe ssful incorporation of nitrogen and erbium into the ZnO *** optical bandgap of ZnO calculated from UV-vis spectroscopy shows a redshift after Er-N co-doping,with the lowest bandgap of 3.215 eV calculated for Zn_(0.97)Er_(0.03)N_(0.01)O_(0.99) *** images demonstrate the formation of nanorods after N-Er co-doping,followed by gradually increase d rod diameter and length after N-Er ***,the photocatalytic activities of ZnO samples we re measured by their ability to facilitate the photodegradation of Rhodamine B under UV *** with 1 mol% N doping exhibits 88% photodegradation of RhB under UV light within 360 min,and the photodegradation and antibacterial activity are greatly improved with Er *** fact,3 mol% Er-1 mol% N doped ZnO NPs demonstrate the highest photocatalytic activity,with approximately 96% degradation after 360 min,as well as superior antibacterial activity against Staphylococcus aureus(Gram-positive bacteria) and Pseudomonas aeruginosa(Gram-negative bacteria) with the highest zone of inhibition(ZOI) of 16 nm,due to nanorod formation,increased reactive oxygen species(ROS),and decreased electron-hole recombination,as validated by SEM,XPS,and PL spectroscopy.

关键词： Chemical co-precipitation Co-doping Bandgap Photocatalysis Rare earths Antimicrobial

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Acute Lymphoblastic Leukemia Presenting as Systemic Juvenile Idiopathic Arthritis: Experience from Bangladesh

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Open Journal of Rheumatology and Autoimmune Diseases 2024年第1期14卷 1-12页

作者： Manik Kumar Talukder Kamrul Laila md. Arif Hossain md. Shafiqul Islam md. Zahidul Islam Kalyan Benjamin Gomes Mujammel haque md. Mahbubul Islam md. Imnul Islam Department of Paediatrics Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh Health Services Dhaka Bangladesh NICVD Dhaka Bangladesh

Background: Acute lymphoblastic leukemia (ALL), the most common paediatric malignancy, is a heterogeneous hematologic disease. ALL patients may present with isolated and persistent osteo-articular complaints, lower incidence of hepatomegaly, splenomegaly or lymphadenopathy without clear laboratory features, and misdiagnosed as systemic juvenile idiopathic arthritis (sJIA). Methods: This was a single center cross sectional study over a period of 4 years. Clinic laboratory profiles of 39 ALL children were compared with 39 age and sex-matched sJIA cases. Result: Among 39 ALL patients 89.7% were initially misdiagnosed as sJIA upon clinical presentation. Majority (66.7%) of ALL patients had oligo-articular joint involvement. In sJIA, small joints of the hands were most commonly involved. The total WBC count was significantly higher in ALL patients (p-value 0.0065). CRP and LDH values between the two groups showed significant differences (p-value 0.00006 and 0.00001 respectively). Conclusion: The presentation of leukemia with arthralgia or arthritis makes the diagnosis difficult for the physicians. The diagnosis of sJIA must be made with caution keeping the possibility of haematological malignancy in mind.

关键词： ALL sJIA Arthritis Arthralgia Musculoskeletal

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ZnO Incorporated Acrylamide Grafted Chitosan Based Composite Film for Advanced Wound Healing Applications

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Open Journal of Applied Sciences 2024年第4期14卷 1034-1051页

作者： Khodeja Afrin Kaniz Fatema Fariha Afrose md. Abdus Samad Azad md. Shamim Akter md. Saiful Alam Papia haque Yeasmin Akter Newaz Mohammed Bahadur Department of Applied Chemistry and Chemical Engineering Noakhali Science and Technology University Noakhali Bangladesh Department of Applied Chemistry and Chemical Engineering University of Dhaka Dhaka Bangladesh

This study was carried out to prepare ZnO nanoparticles incorporated acrylamide grafted chitosan composite film for possible biomedical application especially drug loading in wound healing. ZnO nanoparticles were prepared by co-precipitation method from zinc acetate di-hydrate and incorporated in acrylamide grafted chitosan. FT-IR and TGA of the prepared composite film confirmed the successful incorporation of ZnO nanoparticles in the acrylamide-grafted polymer matrix. SEM images showed that the ZnO nanoparticles were homogeneously distributed on the porous matrix of the composite film. Water uptake and buffer uptake analysis revealed that the composite film could hold water and buffer sufficiently, which facilitated the absorption of exudate from the wound site. Amoxicillin was loaded in the prepared composite film and the maximum loading efficiency was found to be 67.33% with drug concentration of 300 ppm. In vitro studies showed greater antimicrobial activity of drug-loaded composite film compared to both pure film and standard antibiotic disc. Finally, the In vivo mouse model showed maximum healing efficiency compared to conventional gauge bandages because the loading of antibiotic in the film produced a synergistic effect and healing time was reduced.

关键词： Chitosan ZnO Nanoparticles Wound Management Acrylamide Grafting Bacterial Resistance Drug Loading

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