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Journal of biomedical Research 2024年第3期38卷 278-286页

作者： Vishal P.Dubey Varun P.Sureja Dharmeshkumar b.Kheni Department of Scientific and Medical Affairs Sundyota Numandis Probioceuticals Pvt.Ltd.AhmedabadGujarat 380015India

Menopause is characterized by various physical,mental and emotional *** 731®is a standardized extract from Rheum rhaponticum root and has been clinically studied for its role in reducing menopausal *** current systematic review and meta-analysis aimed to evaluate the efficacy of ERr 731®supplementation in alleviating the severity of menopausal *** this review,we searched across three online databases up to March 2023,evaluated the quality of the included studies by the Physiotherapy Evidence Database scale,and assessed the risk of bias by the Cochrane Risk of bias *** then performed a metaanalysis using RevMan software to estimate the pooled mean difference(md).The study protocol was registered in the Prospective Register of Systematic Reviews(CRD42023416808).After screening and evaluation,we included four high-quality studies(a total of 390 participants;the ERr 731®group:193 participants;the control group:197 participants)in the *** results showed that ERr 731®supplementation significantly reduced the Menopause Rating Scale score(md:–15.12;Palysis revealed no effect of individual studies on the overall pooled estimate or overall observed *** current review provides evidence that ERr 731®supplementation is effective in reducing menopause *** bias and high heterogeneity in the results warrant further clinical studies.

关键词： menopause Rheum rhaponticum hot flashes systematic review

Community ecology and spatial distribution of trees in a tropical wet evergreen forest in Kaptai national park in Chittagong Hill Tracts, bangladesh

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Journal of Forestry Research 2014年第2期25卷 311-318页

作者： S. M. Feroz md Rabiul alam Prokash Das Abdullah al Mamun Forestry and Wood Technology Discipline Khulna Universtity

We investigated the floristic composition, woody species diversity and spatial distribution of trees in a tropical wet evergreen forest in Kaptai national park in Chittagong Hill Tracks, bangladesh. We recorded 25 families, 37 genera, 40 species and 1771 woody individuals in a 0.09 ha plot. Euphorbiaceae and Moraceae were the most species- rich families, and Castanopsis, Ficus and Terminaliawere the most species-rich genera. bursera serrata Wall. ex Colebr. was the dominant species in terms of highest importance value （13%）. Trema orientalis （L.） b1 was typically a light demanding species as it appeared in the top can- opy with only one individual having the seventh highest IV, but had no regeneration. The expected maximum number of species （Smax） was 140, indicating that many species may invade the forest as the Sm~ is greater than the recorded total number of species. The nature of the disappear- ance and appearance of species in the present forest reflects instability of floristic composition. The values of Shannon＇s index H＇ and Pielou＇s index J＇（evenness） were 3.36 bit and 0.63, respectively. These values show moderately high species diversity as compared to other subtropical forests in the tropics. In addition, a sample area of 200 m2 in this forest would be sufficient for measuring the diversity indices H＂ and ,/＇, whereas the trend of J＇may indicate the rate of equality of individuals among the different species decreased with increasing area. The distribu- tion pattern for the total stand was completely random. However, the dominant species showed aggregate distribution for small areas, but random distribution for large areas. The spatial association between species showed that the strongest positive interspecific association occurred between Streblus asper Lour. and Castanea indica Roxh. （09 = 0.51）. As a whole, most species were weakly associated with each other, of which 58% species associations were completely negative. The result of cluster analysis s

关键词： Chittagong Hill Tracts floristic composition spatial distribution of trees tropical wet evergreen forest woody species diversity

Intraspecific morphometric diversity of barramundi (Lates calcariferbloch, 1790) in the waters of southern bangladesh

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Journal of Oceanology and Limnology 2019年第4期37卷 1393-1402页

作者： md Reaz CHAKLADER Ashfaqun NAHAR md Abu HANIF Muhammad A. b. SIDDIK School of Molecular and Life Sciences Curtin University Bentley 6102 Australia Department of Marine Fisheries and Oceanography Patuakhali Science and Technology University Patuakhali 8602 Bangladesh Department of Fisheries biology and Genetics Patuakhali Science and Technology University Patuakhali 8602 Bangladesh

A total of 160 barramundi's (Lates calcarifer bloch, 1790) sampled from four rivers (Tentulia, balaswar, bakkhali, and Andarmanik) along the southern coastal region of bangladesh were investigated in terms of morphometric characters to reveal the intraspecific variation. Twenty-five morphometric measurements were extracted using the conventional method and subjected to multivariate analyses (i.e., principal component analysis (PCA), discriminate function analysis (DFA), cluster analysis (CA)) to distinguish individuals from different rivers. The result demonstrated that twenty-two out of 25 measurements was statistically significant (Univariate ANOVA) among all four populations. PCA analysis of morphometric characters resulted in two principal components, PC I and PCⅡ which accounted for 79.25% and 4.28% of the total data variance. PC I-PC Ⅱ plot explained 83.53% of total variance differentiated the population of L. calcarifer into two groups. Discriminate analysis correctly classified about 88.1% of the examined fish into the four areas. The UPGMA dendrogram showed that bakkhali populations were the most morphologically different populations in comparison to other populations, while Andarmanik and balaswar populations were very close to each other. The strong morphometric variation between bakkhali and Tentulia, Andarmanik and balaswar was observed in the present study, suggested the evidence of the separate stock population of barramundi in these locations, which might require distinct stock management strategies for resource sustainability in the waters of southern bangladesh. However, if these findings are supported by further molecular markers and geometric morphometry, this would be a strong indication of different stocks of this population in the four rivers of southern bangladesh.

关键词： intraspecific diversity morphometric characters stock structure Lates calcarifer bangladesh

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镁-铝异种合金自冲铆接接头的力学性能

锻压技术 2024年第9期49卷 157-163,185页

作者：卢杰豪赵伦张俊凯雷乐李承旺刘高宇刘纪元 md Shafiqul Islam 深圳职业技术大学超声技术研究所广东深圳518055 辽宁科技大学材料与冶金学院辽宁鞍山114051 云南开放大学机电工程学院云南昆明650599 瑞典布京理工学院机械学院瑞典卡尔斯克鲁纳37179

镁合金材料在车身轻量化制造方面具有巨大的潜力和应用空间,选取不同厚度的AZ31b镁合金和5083铝合金薄板材料进行自冲铆接,并通过拉伸实验和扫描电镜分析接头的静力学性能及微观组织。结果表明:自冲铆接能实现对AZ31b镁合金和5083铝合... 详细信息

镁合金材料在车身轻量化制造方面具有巨大的潜力和应用空间,选取不同厚度的AZ31b镁合金和5083铝合金薄板材料进行自冲铆接,并通过拉伸实验和扫描电镜分析接头的静力学性能及微观组织。结果表明:自冲铆接能实现对AZ31b镁合金和5083铝合金薄板的有效连接;板厚搭配均匀的自冲铆接接头的整体力学性能最优;镁板厚度较小的自冲铆接接头的失效形式均为上板断裂,其余两组自冲铆接接头的失效形式均为下板拉脱;3组不同镁板厚度组合的自冲铆接接头断口均呈脆性断裂形貌。

关键词：车身轻量化自冲铆接镁合金铝合金力学性能

Hepatitis E virus is a leading cause of acute-on-chronic liver disease:experience from a tertiary centre in bangladesh

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Hepatobiliary & Pancreatic Diseases International 2009年第1期8卷 50-52页

作者： Mamun-al Mahtab Salimur Rahman Mobin Khan md.Fazal Karim Department of Hepatology Bangabandhu Sheikh Mujib Medical University

bACKGROUND:Acute-on-chronic liver failure(ACLF) is common in *** viral E hepatitis is sporadically encountered in this country each year,with a rising incidence in the rainy *** study aimed to identify the etiology of ACLF in bangladesh. METHODS:In this retrospective study,69 ACLF patients were *** presented to our department at the bangabandhu Sheikh Mujib Medical University in *** of diseases was recorded and appropriate investigations were conducted in all patients. RESULTS:Acute hepatitis E virus(HEV)infection was positive in 21.7%(15/69)of the patients,while 14.5% (10/69)had *** gastrointestinal tract hemorrhage was seen in 4.3%of the patients(3/69),while another 4.3%(3/69)had a positive history for alcohol or *** of the patients tested positive for hepatitis A virus infection and no evidence of hepatitis b virus flare was found in any *** specific cause for ACLF could be identified. CONCLUSIONS:Acute HEV infection is a leading cause of ACLF in *** patients were thought to have decompensation of cirrhosis,but subsequently were recognized as having ACLF by a retrospective review according to the definition of the Asian Pacific Association for the Study of the Liver Working Party Meeting on ACLF in New Delhi in early 2008.

关键词： acute-on-chronic liver failure hepatitis E virus septicemia

Growth inhibitory response and ultrastructural modification of oral-associated candidal reference strains (ATCC) by Piper betle L. extract

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International Journal of Oral Science 2014年第1期6卷 15-21页

作者： Mohd-al-Faisal Nordin Wan Himratul-Aznita Wan Harun Fathilah Abdul Razak md Yusoff Musa Department of Oral biology and biomedical Sciences Faculty of Dentistry University of Malaya Institute of biological Sciences Faculty of ScienceUniversity of Malaya

Candida species have been associated with the emergence of strains resistant to selected antifungal agents. Plant products have been used traditionally as alternative medicine to ease mucosal fungal infections. This study aimed to investigate the effects of Piper betle extract on the growth profile and the ultrastructure of commonly isolated oral candidal cells. The major component of Po betle was identified using liquid chromatography-mass spectrophotometry （LC-MS/MS）. Seven ATCC control strains of Candida species were cultured in yeast peptone dextrose broth under four different growth environments：（i） in the absence of P. betle extract; and in the presence of P. beUeextract at respective concentrations of （ii） 1 ***-1; （iii） 3 ***-1; and （iv） 6 ***- 1 The growth inhibitory responses of the candidal cells were determined based on changes in the specific growth rates （μ）. Scanning electron microscopy （SEM） was used to observe any ultrastructural alterations in the candida colonies. LC-MS/MS was performed to validate the presence of bioactive compounds in the extract. Following treatment, it was observed that the p-values of the treated cells were significantly different than those of the untreated cells （P〈0.05）, indicating the fungistatic properties of the P. beUe extract. The candidal population was also reduced from an average of 13.44× 10^6 to 1.78×10^6 viable cell counts （CFU）.mL-1, SEM examination exhibited physical damage and considerable morphological alterations of the treated cells. The compound profile from LC-MS/MS indicated the presence of hydroxybenzoic acid, chavibetol and hydroxychavicol in P. betle extract. The effects of P. betle on candida cells could potentiate its antifungal activity.

关键词： antifungal activity Candida cell morphology growth inhibitory effect Piperbetle L.

HbsAg, HbcAg, and combined HbsAg/HbcAg-based therapeutic vaccines in treating chronic hepatitis b virus infection

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Hepatobiliary & Pancreatic Diseases International 2013年第4期12卷 363-369页

作者： Sheikh Mohammad Fazle Akbar Mamun al-Mahtab Mohammad Helal Uddin md. Sakirul Islam Khan Department of Medical Sciences Toshiba General HospitalTokyo Japan Department of Hepatology Bangabandhu Sheikh Mujib Medical UniversityDhaka Bangladesh Clinical Research Organization Dhaka Bangladesh Laboratory of Animal Production Faculty of Agriculture Ehime UniversityMatsuyama Japan

bACKGROUND: As the host immunity is diminished in patients with chronic hepatitis b (CHb), different approaches have been used to up-regulate their immune responses to produce therapeutic effects. but, cytokines, growth factors and polyclonal immune modulators could not exhibit sufficient therapeutic effects in these patients. Immune therapy with HbV-related antigens (vaccine therapy) has been used in CHb patients. but there is a paucity of information about the design of HbV antigen-based immune therapy in these patients. DATA SOURCE: Preclinical and clinical studies on immune therapy with HbsAg-based vaccine, HbcAg and combination of HbsAg/HbcAg-based vaccines have been discussed. RESULTS: HbsAg-based prophylactic vaccine was used as an immune therapeutic agent in CHb patients; however, monotherapy with HbsAg-based immune therapy could not lead to sustained control of HbV replication and/or liver damages. HbsAg-based vaccine was used as a combination therapy with cytokines, growth factors, and antiviral drugs. HbsAg-based vaccine was also used for cell-based therapy. However, satisfactory therapeutic effects of HbsAg-based vaccine could not be documented in CHb patients. In the mean time, evidences have supported that HbcAg-specific immunity is endowed with antiviral and liver protecting capacities in CHb patients. Recent data concentrate on the clinical use of combined HbsAg- and HbcAg-based vaccines in CHb ***: Antigen-based immune therapy with HbV- related antigens may be an alternative method for the treatment of CHb patients but proper designs of antigens, types of adjuvants, dose of vaccinations, and routes of administration need further analyses for the development of an effective regimen of immune therapy against HbV.

关键词： chronic hepatitis b HbsAg vaccine HbsAg/HbcAg vaccine immune therapy therapeutic vaccines

The magnetosheath at high spectral resolution

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Earth and Planetary Physics 2024年第1期8卷 234-246页

作者： K.D.Küntz D.Koutroumpa W.R.Dunn A.Foster F.S.Porter D.G.Sibeck b.Walsh The Henry A.Rowland Department of Physics and Astronomy Johns Hopkins University3701 San Martin DriveBaltimoreMD21218USA NASA Goddard Space Flight Center 8800 Greenbelt RoadGreenbeltMD 20771USA LATMOS-OVSQ CNRSUVSQ Paris-SaclaySorbonne Université11 Boulevard d’Alembert78280GuyancourtFrance Department of Physics and Astronomy University College LondonLondonUK The Centre for Planetary Science at UCL/birkbeck Gower StreetLondon WC1E 6BTUK Center for Astrophysics Harvard University&Smithsonian Institution60 Garden StreetCambridgeMA 02138USA Center for Space Physics Boston University110 Cummington MallBostonMAUSA

While we eagerly anticipate SMILE’s(Solar wind Magnetosphere Ionosphere Link Explorer)unprecedented X-ray observations of the Earth’s magnetosheath and the initiation of a new era of magnetospheric research,it seems appropriate to look ahead to the abilities of the next generation of astrophysics *** these,the Line Emission Mapper(LEM),a large aperture micro-calorimeter based mission,is currently planned to be able to observe the magnetosheath at high spectral resolution(~2 eV).With a field of view of~30′,LEM will allow higher spatial resolution and higher cadence measurement of the motion of a very small portion of the magnetopause over relatively short periods of time(multiple hours),complementing SMILE’s global ***’s strength is its spectral *** will be able to measure the abundance of a broad range of elements and ionization states,many of which are inaccessible to current in situ instruments,and will be able to separate the emission from the magnetosheath from the emission from the cosmic X-ray background using the difference in their relative velocities.

关键词： magnetosheath charge exchange solar wind abundances

Capturing transition and non-transition flows with a new shear stress transport model

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Chinese Journal of Aeronautics 2023年第3期36卷 121-136页

作者： md Mizanur RAHMAN School of Mechanical Engineering Hangzhou Dianzi UniversityHangzhou 310018China

A new Shear Stress Transport(SST)k-ω model is devised to integrate salient features of both the non-transitional SST k-ω model and correlation-based γ-Re_(θ) transition *** exceptionally simplified approach is applied to extend the New SST(NSST)model capabilities toward transition/non-transition ***’s stress-intensity factor R_(b)=|-uv|/k can be parameterized with the wall-distance dependent Reynolds number Re_(y)=√ky/v;however,as the Re_(y)is replaced by a“flow-structure-adaptive”parameter R_(μ)=v_(T)/v,the resulting R_(b)is capable of capturing various transition phenomena *** prospective stress-intensity parameter R_(b)=R_(b)(Re_(y),R_(μ))is incorporated in the constitutive relations for eddy-viscosity v_(T) and production term P_(k).The proposed formulation is intrinsically plausible,having a dramatic impact on the prediction of bypass,separation-induced and natural transitions together with non-transitional *** extra viscous-production term P_(k)^(lim) is added with the k-equation to ensure proper generation of k at the viscous sublayer when computing separation-induced transition over a Low-Reynolds Number(LRN)*** demonstrate that the NSST k-ω model maintains an excellent consistency with both SST k-ω and γ-Re_(θ) models.

关键词： γ-Re_(θ)model Non-transition Stress-intensity parameter SST model Transition

Pressure-dependent physical properties of cubic SrΒO3(Β=Cr,Fe)perovskites investigated by density functional theory

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Chinese Physics b 2020年第12期29卷 212-220页

作者： md Zahid hasan md Rasheduzzaman Khandaker Monower Hossain Department of Electrical and Electronic Engineering International Islamic University ChittagongKumiraChittagong-4318Bangladesh Department of Materials Science and Engineering University of RajshahiRajshahi-6205Bangladesh

We perform the first-principles investigations of the structural,elastic,electronic,and optical properties of SrbO3(b=Cr,Fe)perovskites under pressure based on density functional theory(DFT).This is the first detailed pressure-dependent study of the physical properties for these *** calculated structural parameters are consistent with the existing experimental results and slightly decrease with the application of *** mechanical properties are discussed in detail and reveal that the SrCrO3 is harder than *** pressure,these compounds behave like half-metals,confirmed by their band structure and density of *** the SrCrO3 retains its half-metallic nature under pressure,SrFeO3 becomes metallic for both up-spin and down-spin *** charge density and bond overlap population reveal the covalent nature of Cr–O bond and Fe–O bond in the studied *** optical properties of SrbO3,also discussed for the first time,reveal some interesting results.

关键词： density functional theory(DFT) effects of pressure electronic band structure optical properties