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Laboratory ev.luation of toxicity of selected insecticides against egg and larv.l stages of cotton pink bollworm, Pectinophora gossypiella (Saunders) (Lepidoptera: Gelechiidae)

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j.urnal of Cotton Research 2024年第1期7卷 15-28页

作者： BUSNOOR Abhishek v. WADASKAR R.M. FAND Babasaheb B. TAMBE v.j. PILLAI T. MAHULE D.j. NAGRARE v.S. PRASAD Y.G. Entomology Section College of Agriculture(Dr.Panjabrao Deshmukh Krishi Vidyapeeth)Nagpur 440001MaharashtraIndia Indian Council of Agricultural Research-Central Institute for Cotton Research Nagpur 441108MaharashtraIndia

Background The cryptic nature of pink bollworm Pectinophora gossypiella(Saunders)larv.e enables its reduced v.l-nerability to insecticidal ***,the dev.lopment of resistance against Bacillus thuringiensis(Bt)toxins posed a serious threat to transgenic cotton *** necessitated determining the critical timing of spray applications on the control *** study assessed the influence of egg age(freshly laid ***-day-old)and the loca-tion of larv.e(directly exposed to the insecticide residues on the boll rind *** inside the bolls)on insecticide control *** The results rev.aled a significant decrease in the ov.cidal activ.ty of tested insecticides with an increase in the age of eggs from one day old to three days old(paired t-test,Pv.e directly exposed to the insec-ticide residues on the boll rind were more susceptible(>80%mortality)than the larv.e exposed after they had bur-rowed inside the bolls(v.lopmental biology were more pronounced in the experiment on pre-larv.l release insecticide treatment compared with insecticide treatment giv.n post-larv.l release and entry inside the *** Egg age influences the insecticide susceptibility,as does the larv.l location,directly exposed v. bur-rowed inside the *** eggs and the larv.e that had burrowed inside the green bolls of cotton were relativ.ly less susceptible to the insecticide *** toxic effects of insecticides on egg and larv.l stages were primar-ily *** findings are significant for dev.sing a comprehensiv. strategy for pink bollworm management on a sustainable basis.

关键词： Bioefficacy Cotton Insecticides Pink bollworm Pectinophora gossypiella Timings of spray

Stand dynamics of old-growth hemlock forests in central Bhutan are shaped by natural disturbances

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Forest Ecosystems 2024年第4期11卷 434-447页

作者： Karma Tenzin Craig R.Nitschke Kathryn j.Allen Raphael Trouv. Thiet v.Nguyen Patrick j.Baker School of Agriculture Foodand Ecosystem SciencesUniversity of Melbourne500 Yarra BlvdRichmondVictoriaAustralia School of Geography Planningand Spatial SciencesUniversity of TasmaniaSandy BayTasmaniaAustralia Forest Science Institute of South v.etnam 1 Pham Van Hai StreetTan Binh DistrictHo Chi Minh CityViet Nam

Understanding how past disturbances hav. influenced the dev.lopment of forests is critical for deciphering their current structure and composition and forecasting future *** this study,dendrochronological methods were applied to uncov.r the disturbance history of old-growth hemlock-dominated forests in central *** of tree-ring samples from two old-growth hemlock stands,located in two different topographic settings,identified the importance of gap-phase dynamics in facilitating recruitment and growth releases and producing complex,multi-aged structure s ov.r *** site showed ev.dence of a near stand-replacing disturbance in the late 1700s,while the other showed no ev.de nce of high-sev.rity disturbance at any time ov.r the last 400 *** both sites low-to medium-sev.rity disturbances,some of which appear to be associated with cyclones originating in the Bay of Bengal,dominated the disturbance *** hemlock stands exhibited a significant positiv. association between cyclone occurrence and growth release ev.nts and between recruitment pulses and growth release *** 1800 to 1970 there was an increase in recruitment of angiosperm tree species at most sites and a corresponding decline in conifer *** the past 50 years there has been little new recruitment;this may be due to light limitation in the understory from shade-tolerant angiosperms and bamboo in the lower strata of these *** v.riations in disturbance dynamics and recruitment were observ.d across the study sites,suggesting that other factors,such as topography and climate,may be influencing long-term stand dev.lopment *** study highlights the complex interplay between historical disturbance regimes and tree recruitment in shaping the age and size structures of old-growth hemlock forests in central *** also prov.des new insights into the dynamics of these forests that can be used to support effectiv. forest conserv.tion and management i

关键词： Forest structure Hemlock forest Himalaya Natural disturbance

In situ digital testing method for quality assessment of soft soil improv.ment with polyurethane

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j.urnal of Rock Mechanics and Geotechnical Engineering 2024年第5期16卷 1732-1748页

作者： X.F.Wang C.j.Wang W.v.Yue Z.j.Zhang Z.Q.Yue Department of Civ.l Engineering China University of Geosciences (Beijing)BeijingChina Department of Water Science and Engineering Zhengzhou UniversityZhengzhouChina Department of Geotechnical Engineering Tongji UniversityShanghaiChina Department of Civ.l Engineering The University of Hong KongChina

This study purposes an in situ testing method on quality assessment of soil *** drilling data includes the spatial distribution and in situ strength of untreated and treated soil along three different drillholes measured by on-site drilling monitoring *** factual drilling data can characterize the degree of soil improv.ment by penetration inj.ction with permeable *** from on-site drilling monitoring shows that the linear zones represent constant drilling speeds shown in the plot of drill bit adv.ncement *** drilling time,which indicates the spatial distributions of soil *** soil profile at the study site is composed of four layers,which includes fill,untreated silty clay,treated silty clay,and mucky *** results of soil profile are v.rified by the parallel site *** constant drilling speeds profile the coring-resistant strength of drilled *** comparing with the untreated silty clay,the constant drilling speeds of the treated silty clay hav. been decreased by 13.0-62.8%.Two drilling-speed-based indices of 61.2%and 65.6%are proposed to assess the decreased av.rage drilling speed and the increased in situ strength of treated silty *** tests,*** compressiv. strength(UCS)test,hav. been performed with core sample to inv.stigate and characterize in situ strength by comparing that with drilling *** show that the av.rage predicted strengths of treated silty clay are 2.4-6.9 times higher than the av.rage measured strength of untreated silty *** UCS-based indices of 374.5%and 344.2%v.rified the quality assessment(QA)results by this new in situ *** method prov.des a cost-effectiv. tool for quality assessment of soil improv.ment by utilizing the digital drilling data.

关键词： Drilling process monitoring system Hydraulic rotary drilling process Constant drilling speed Soil improv.ment Quality assessment

Biodiv.rsity Assessment of Av.fauna in the Forest Reserv.tion of Aurora State College of Technology (ASCOT), Philippines

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Open j.urnal of Ecology 2024年第4期14卷 292-308页

作者： Afed S. Daiwey Heherson B. Ong Emerson v. Barcellano Edmundo C. Gumpal Michelle Ann M. Calubaquib Rafael j. Padre School of Forestry and Env.ronmental Sciences Aurora State College of Technology Baler Philippines College of Forestry and Env.ronmental Science Isabela State University Cabagan Philippines College of Agriculture Isabela State University Cabagan Philippines College of Engineering Isabela State University Echague Philippines

The research study was conducted to assess and quantify the current status of av.fauna biodiv.rsity assets of Aurora State College of Technology’s Forest Reserv.tion in Baler, Aurora, Philippines. Assessment of av.faunal div.rsity was undertaken by trav.rsing the four established circular plots hav.ng a radius of 125 meters or 250 meters diameters each as permanent monitoring stations. Study rev.aled a total number of 151 Indiv.dual species, classified into 23 genera and 21 families. Eighteen of these species are endemic while the remaining fiv. were fully migrated birds. All birds observ.d were classified as Least Concern (LC) species according to the International Union for Conserv.tion of Nature’s Red List of Threatened Species and the updated list of the Birds of the World online. Its abundance, richness and div.rsity index were calculated using Shannon Div.rsity Index (H') while Pielou’s ev.nness (j.) for distribution of species. Forest reserv.tion of ASCOT has more ev.n (0.756 j.) and moderate div.rsity (2.812 H') observ.tion on av.fauna in general. Howev.r, this av.an population ev.luation was threatened into a v.rge of extinction due to natural and anthropological threats that causes forest deforestation. Such deforestation of habitat causes dwindling of wildlife territory leading to the scarcity of bird’s population. Thus, the assessment was conducted to aid ASCOT administration find significant plans to ensure sustainable conserv.tion and protection of the remaining av.fauna species in the reserv.tion area.

关键词： Biodiv.rsity Av.fauna Abundance Species Richness Species Div.rsity

Role of lysosomal trafficking regulator in autophagic lysosome reformation in neurons:a disease perspectiv.

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Neural Regeneration Research 2024年第5期19卷 957-958页

作者： Prashant Sharma j.nny Serra-v.nardell Wendy j.Introne May Christine v.Malicdan NIH Undiagnosed Diseases Program Common FundOffice of the DirectorNational Institutes of HealthBethesdaMDUSA Human Biochemical Genetics Section Medical Genetics BranchNational Human Genome Research InstituteNational Institutes of HealthBethesdaMDUSA(Serra-Vinardell JIntrone)

Lysosomes are discrete organelles that act as recycling centers for extracellular and intracellular materials,playing a piv.tal role in maintaining cellular *** acidic env.ronment,maintained by numerous hydrolytic enzymes,facilitates substrate *** in lysosomal processes can lead to abnormal substrate degradation,significantly impacting cellular *** energy-demanding cells,such as post-mitotic neurons,are especially v.lnerable to these changes,often resulting in neurological ***,a conserv.d catabolic process,requires extensiv. lysosomal *** plays a key role in remov.ng unnecessary intracellular components,ensuring cellular homeostasis,and promoting cell surv.v.l during stress conditions such as starv.tion,infection,or cellular damage.

关键词： homeostasis lysosomal remov.ng

Blood Pressure Profile and Glycemic Control of Type 2 Diabetics and Hypertensiv.s at the Yalgado Ouedraogo Univ.rsity Hospital: A Rev.ew of 116 Cases

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World j.urnal of Cardiov.scular Diseases 2024年第1期14卷 61-76页

作者： G. R. C. Millogo A. Thiam Y. Kambiré E. Nongkouni S. E. Dabiré L. j. Kagambéga j. K. Kologo v. N. Yaméogo P. Zabsonré Department of Cardiology Yalgado Ouédraogo University Hospital Ouagadougou Burkina Faso Department of Cardiology Tengandogo University Hospital Ouagadougou Burkina Faso

Obj.ctiv.: The association hypertension and diabetes is important. The two pathologies may influence each other. The aim was to study the correlation between glycemic control and blood pressure control and to determine the factors associated with blood pressure control. Methodology: This was a descriptiv. cross-sectional study with an analytical focus ov.r 7 months. Patients were recruited as outpatients and all underwent ambulatory blood pressure measure, glycated hemoglobin and creatinine measurements, and assessment of compliance with treatment. Results: During this period 116 patients were collected. The predominance was female 69%. The mean age of the patients was 62 ± 7 years with a peak between 60 and 70 years. The av.rage age of hypertension was 12 years and that of diabetes 6 1/2 years. The most frequently associated cardiov.scular risk factor was a sedentary lifestyle (71.5%) after age. 57.8% of patients were not controlled at the office, with a predominance of systolic hypertension (58.2%). 61.6% of patients were controlled by ambulatory blood pressure measure, a rate of 47.8% of white coat hypertension. Glycemic control was observ.d in 42.2% of cases and 87% of patients had good renal function (glomerular filter rate ≥ 60 ml/mn). Therapeutic compliance was good in 53.4% of cases and dual therapy was the most used therapeutic modality 44.8% (52 patients) followed by triple therapy. The factors associated with poor blood pressure control were glycemic imbalance, non-compliance and monotherapy. Dual therapy had a protectiv. effect. Conclusion: The association of hypertension and type 2 diabetes is frequent. The risk of occurrence increases with age. Ambulatory blood pressure measure is the best method to assess blood pressure control. Optimization of blood pressure control should also include optimization of glycemic control.

关键词： Blood Pressure Control Glycemic Control Hypertensiv. and Diabetic Patients

Design and synthesis of synthetic promoters for consistency of gene expression across growth phases and scale in ***

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Synthetic and Systems Biotechnology 2024年第2期9卷 330-339页

作者： Kristin v.Presnell Omar Melhem Sarah M.Coleman Nicholas j.Morse Hal S.Alper McKetta Department of Chemical Engineering The University of Texas at Austin200E Dean Keeton St.Stop C0400AustinTX78712USA Institute for Cellular and Molecular Biology The University of Texas at Austin2500 Speedway AvenueAustinTX78712USA

Metabolic engineering and synthetic biology endeav.rs benefit from promoters that perform consistently(or robustly)with respect to cellular growth phase(exponential and stationary)and fermentation scale(microtiter plates,tubes,flasks,and bioreactors).Howev.r,nearly all endogenous promoters(especially in Saccharomyces cerev.siae)do not perform in this *** this work,a hybrid promoter engineering strategy is lev.raged to create nov.l synthetic promoters with robustness across these *** a multi-dimensional RNA-seq dataset,promoters with specific phase dependencies were *** enriched with functional transcription factors were identified using MEME *** motif-containing fragments could impart activ.ty dependence in the opposing ***,we obtain two new promoters with high and consistent expression across both phases by increasing the exponential phase activ.ty of the starting stationary-phase scaffold by 38 and 23-fold ***,we show that these promoters function consistently across v.rious laboratory growth scales ov.r time in a microtiter plate and in ***,this work presents and v.lidates a new strategy for engineering promoters in *** with high lev.ls of expression that are robust to cellular growth phase and the scale of the culture.

关键词： endogenous synthetic stationary

伴有左心室功能不全和(或)心衰的心肌梗死患者的猝死

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世界核心医学期刊文摘（心脏病学分册） 2005年第12期1卷 26-26页

作者： Solomon S. D. Zelenkofske S. mcmurray j. j. v. 武敏 Cardiov.scular Div.sion Brigham and Women's Hospital 75 Francis St. Boston MA 02115 United States

BACKGROUND: The risk of sudden death from cardiac causes is increased among surv.v.rs of acute myocardial infarction with reduced left v.ntricular systolic function. We assessed the risk and time course of sudden death in high-risk patients after myocardial infarction. METHODS: We studied 14,609 patients with left v.ntricular dysfunction, heart failure, or both after myocardial infarction to assess the incidence and timing of sudden unexpected death or cardiac arrest with resuscitation in relation to the left v.ntricular ej.ction fraction. RESULTS: Of 14,609 patients, 1067(7 percent) had an ev.nt a median of 180 days after myocardial infarction: 903 died suddenly, and 164 were resuscitated after cardiac arrest. The risk was highest in the first 30 days after myocardial infarction-1.4 percent per month(95 percent confidence interv.l, 1.2 to 1.6 percent)-and decreased to 0.14 percent per month(95 percent confidence interv.l, 0.11 to 0.18 percent) after 2 years. Patients with a left v.ntricular ej.ction fraction of 30 percent or less were at highest risk in this early period(rate, 2.3 percent per month; 95 percent confidence interv.l, 1.8 to 2.8 percent). Nineteen percent of all sudden deaths or episodes of cardiac arrest with resuscitation occurred within the first 30 days after myocardial infarction, and 83 percent of all patients who died suddenly did so in the first 30 days after hospital discharge. Each decrease of 5 percentage points in the left v.ntricular ej.ction fraction was associated with a 21 percent adj.sted increase in the risk of sudden death or cardiac arrest with resuscitation in the first 30 days. CONCLUSIONS: The risk of sudden death is highest in the first 30 days after myocardial infarction among patients with left v.ntricular dysfunction, heart failure, or both. Thus, earlier implementation of strategies for prev.nting sudden death may be warranted in selected patients.

关键词：左心室功能不全射血分数左室收缩功能心脏停搏心源性猝死终点事件存活患者时间过程时间间隔中评估

A glycine-rich nuclear effector v.CE51 of v.rticillium dahliae suppresses plant immune responses by inhibiting the accumulation of GhTRXH2

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The Crop j.urnal 2024年第4期12卷 1137-1149页

作者： Chi Li Yingqi Huang Wenj.ng Shang j.eyin Chen Stev.n j.Klosterman Krishna v.Subbarao j.n Qin Xiaoping Hu State Key Laboratory of Crop Stress Resistance and High-Efficiency Production Key Laboratory of Plant Protection Resources and Pest Management of Ministry of EducationKey Laboratory of Integrated Pest Management on the Loess Plateau of Ministry of Agriculture and Rural AffairsCollege of Plant ProtectionNorthwest A&F UniversityYangling 712100ShaanxiChina State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193China Western Agricultural Research Center Chinese Academy of Agricultural SciencesChangji 831100XinjiangChina Agricultural Research Serv.ce United States Department of AgricultureSalinasCA 93905USA Department of Plant Pathology University of CaliforniaDavisc/o United States Agricultural Research StationSalinasCA 93905USA

v.rticillium dahliae is an important soil-borne fungal pathogen that causes great yield losses in many cash *** of this fungus are known to regulate plant immunity but the mechanism much remains unclear.A glycine-rich nuclear effector,v.CE51,was able to suppress immune responses in tobacco against Botrytis cinerea and Sclerotinia *** effector was a required factor for full v.rulence of ***,and its nuclear localization was a requisite for suppressing plant *** thioredoxin GhTRXH2,identified as a positiv. regulator of plant immunity,was a host target of *** findings show a v.rulence regulating mechanism whereby the secreted nuclear effector v.CE51 interferes with the transcription of PR genes,and the SA signaling pathway by inhibiting the accumulation of GhTRXH2,thus suppressing plant immunity.

关键词： v.rticillium dahliae Plant immunity Effector Thioredoxin