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A randomized controlled trial of Promoting Physical Activity in Regional and Remote Cancer Survivors(PPARCS)

Journal of Sport and Health Science 2024年第1期13卷 81-89页

作者： Sarah J.Hardcastle Chloe maxwell-Smith Vinicius Cavalheri Terry Boyle Marta Leyton Román Cameron Platell Michael Levitt Christobel Saunders Frank Sardelic Sophie Nightingale Jacob McCormick Craig Lynch Paul A.Cohen max bulsara Dana Hince Sport and Physical Activity Research Centre Sheffield Hallam UniversitySheffieldS102BPUK Institute for Health Research The University of Notre DameFremantleWA 6959Australia Curtin School of Population Health Curtin UniversityPerthWA 6845Australia Curtin School of Allied Health Curtin UniversityPerthWA 6845Australia Allied Health South Metropolitan Health ServiceMurdochWA 6150Australia Australian Centre for Precision Health University of South AustraliaAdelaideSA 5001Australia Department of Didactics of Musical Plastic and Body ExpressionUniversity of ExtremaduraCaceres 10071Spain St.John of God Subiaco Hospital PerthWA 6008Australia Department of Surgery University of MelbourneMelbourneVIC 3010Australia Tamara Private Hospital TamworthNSW 2340Australia Peter MacCallum Cancer Centre MelbourneVIC 3000Australia College of Health and Medicine Australian National UniversityCanberraACT 2600Australia Division of Obstetrics and Gynaecology Medical SchoolUniversity of Western AustraliaPerthWA 6009Australia

Background:Physical activity(PA)is important for cancer survivors.Trials of remotely delivered interventions are needed to assist in reaching under-served non-metropolitan cancer survivors.The objective of this study was to ascertain whether wearable technology,coupled with health coaching was effective in increasing PA in breast and colorectal cancer survivors living in regional and remote areas in Australia.Methods:Cancer survivors from 5 states were randomized to intervention and control arms.Intervention participants were given a Fitbit Charge 2TMand received up to 6 telephone health coaching sessions.Control participants received PA print materials.Accelerometer assessments at baseline and 12 weeks measured moderate-to-vigorous PA(MVPA),light PA,and sedentary behavior.Results:Eighty-seven participants were recruited(age=63±11 years;74(85%)female).There was a significant net improvement in MVPA of 49.8 min/week,favoring the intervention group(95%confidence interval(95%CI):13.6-86.1,p=0.007).There was also a net increase in MVPA bouts of 39.5 min/week(95%CI:11.9-67.1,p=0.005),favoring the intervention group.Both groups improved light PA and sedentary behavior,but there were no between-group differences.Conclusion:This’s the first study to demonstrate that,when compared to standard practice(i.e.,PA education),a wearable technology intervention coupled with distance-based health coaching,improves MVPA in non-metropolitan cancer survivors.The results display promise for the use of scalable interventions using smart wearable technology in conjunction with phone-based health coaching to foster increased PA in geographically disadvantaged cancer survivors.

关键词： Behavior change Exercise Health disparities Oncology Wearable technology

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乳腺癌后妊娠:人群为基础的研究

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英国医学杂志中文版 2007年第3期10卷 149-152页

作者： Angela Ives Christobel Saunders max bulsara James Semmens 郑敏哲（译）曹杨（译）潘凌亚（校） School of Surgeryand Pathology （M507） University of Western Australia CrawleyWestern Australia 6009 School of Population Health （ M431 ） University of Western School of Public Health Curtin University of Technology BentleyWestem Australia 6848 不详

目的识别乳腺癌存活的妇女及其后的妊娠,以确定妊娠率(比例)、处理、乳腺癌预后、以及初次妊娠的结局。设计人群为基础的描述性研究,病例来源于西澳大利亚数据连锁系统,并通过对医疗表格进行回顾分析进一步确认。补充资料来自于医院及... 详细信息

目的识别乳腺癌存活的妇女及其后的妊娠,以确定妊娠率(比例)、处理、乳腺癌预后、以及初次妊娠的结局。设计人群为基础的描述性研究,病例来源于西澳大利亚数据连锁系统,并通过对医疗表格进行回顾分析进一步确认。补充资料来自于医院及门诊记录。地点西澳大利亚,1982—2003年。对象年龄<45岁,确诊乳腺癌后妊娠的妇女。主要结局评估指标妊娠结局及妊娠率,生存情况,从诊断到妊娠的时间。结果 62名(54%)妇女在诊断为乳腺癌后2年内妊娠。其中,29例人工流产,27例活产,6例自然流产。采用比例风险回归模型分析继发妊娠与总生存时间改善的相关性(风险比0.59,95%可信区间0.37～0.95)。将该模型按从诊断乳腺癌至继发妊娠的时间进行分层,发现诊断至少24个月后的继发妊娠与总生存率的改善相关(0.48,0.27～0.83),而在确诊6个月后妊娠的妇女中这种保护作用并不显著。结论我们的研究不支持目前推荐绝经前诊断乳腺癌的妇女在试图妊娠前应等待两年的医疗建议。这一建议可能适用于那些正在接受治疗、或在诊断时患有全身性疾病的妇女。但对于那些病灶局限的妇女,在完成治疗6个月后的早期妊娠不一定降低生存。

关键词：乳腺癌预后妊娠率人群回归模型分析正在接受治疗澳大利亚医疗表格全身性疾病

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Effect of airplane transport of donor livers on post-liver transplantation survival

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World Journal of Gastroenterology 2016年第41期22卷 9154-9161页

作者： Yi Huang Gerry MacQuillan Leon A Adams George Garas Megan Collins Albert Nwaba Linjun Mou max K bulsara Luc Delriviere Gary P Jeffrey School of Medicine and Pharmacology University of Western Australia Western Australian Liver Transplantation Service Sir Charles Gairdner Hospital Institute of Health Research University of Notre Dame

AIM To evaluate the effect of long haul airplane transport of donor livers on post-transplant outcomes. METHODS A retrospective cohort study of patients who received a liver transplantation was performed in Perth, Australia from 1992 to 2012. Donor and recipient characteristics information were extracted from Western Australian liver transplantation service database. Patients were followed up for a mean of six years. Patient and graft survival were evaluated and compared between patients who received a local donor liver and those who received an airplane transported donor liver. Predictors of survival were determined by univariate and multivariate analysis using cox regression.RESULTS One hundred and ninety-three patients received alocal donor liver and 93 patients received an airplane transported donor liver. Airplane transported livers had a significantly lower alanine transaminase(mean: 45 U/L vs 84 U/L, P = 0.035), higher donor risk index(mean: 1.88 vs 1.42, P < 0.001) and longer cold ischemic time(CIT)(mean: 10.1 h vs 6.4 h, P < 0.001). There was a weak correlation between CIT and transport distance(r2 = 0.29, P < 0.001). Mean follow up was six years and 93 patients had graft failure. Multivariate analysis found only airplane transport retained significance for graft loss(HR = 1.92, 95%CI: 1.16-3.17). One year graft survival was 0.88 for those with a local liver and was 0.71 for those with an airplane transported liver. One year graft loss was due to primary graft non-function or associated with preservation injury in 20.8% of recipients of an airplane transported liver compared with 4.6% in those with a local liver(P = 0.027). CONCLUSION Airplane transport of donor livers was independently associated with reduced graft survival following liver transplantation.

关键词：飞机交通冷 ischemic 时间接枝幸存施主地点机关损坏

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