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World Journal of Gastrointestinal Oncology 2013年第11期5卷 198-203页

作者： Osama E Rahma mauricio Burotto Luisa Matos Do Canto Alexandre A Germanos Bassem R Haddad John L Marshall Medical Oncology Branch National Cancer Institute the Lombardi Comprehensive Cancer Center Georgetown University Medical Center Whitman College the Ruesch Center for the Cure of GI Cancers Georgetown University Medical Center

We are reporting the longest disease-free interval ever published for colorectal cancer, using gene profiling to confirm the linkage of the primary and metastasis. This rare case reports on a patient with late recurrence of colorectal cancer in the lung 19 years after its initial diagnosis. We used high-resolution array CGH(aCGH) to analyze the genetic aberrations of both the primary rectal and the recurrent metastatic lung lesions. Interestingly, we found striking similarities between the two lesions, despite the 19 years disease-free *** addition, most of the genes that were previously reported to be associated with a high recurrence score showed copy number gains by aCGH in one or both lesions. Our findings suggest that aCGH may be a helpful tool in analyzing the origin of metastatic lesions and reflect the need for a better understanding of the characteristics of the rectal tumors with a late recurrence potential.

关键词： Colorectal cancer Genetic aberrations Delayed Recurrence High-resolution array CGH

ST Elevation Myocardial Infarction in the elderly

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Journal of Geriatric Cardiology 2012年第2期9卷 108-114页

作者： Marcelo Franken Amit Nussbacher Alberto Liberman mauricio Wajngarten INCOR Heart Institute University of Sao Paulo Medical School Av. Dr. Endas Carvalho de Aguiar 44-05403-000 S6o Paulo Brasil PUC- Campinas Medical School Rodovia Dom Pedro I Ion 136 Parque das Universidades Campinas (SP) CEP13086-900 Brasil

Acute coronary syndromes （ACS） are the leading causes of death in the elderly. The suspicion and diagnosis of ACS in this age group is more difficult, since typical angina is less frequent. The morbidity and mortality is greater in older age patients presenting ACS. Despite the higher prevalence and greater risk, elderly patients are underrepresented in major clinical trials fi：om which evidence based recommendations are formulated. The authors describe, in this article, the challenges in the diagnosis and management of ST elevation myocardial infarction in the elderly, and discuss the available evidence.

关键词： Myocardial Infarction Acute coronary syndromes Elderly people Management

Irrigation's effect and applied selection on the fiber quality of Ethyl MethaneSulfonate(EMS)treated upland cotton(Gossypium hirsutum L.)

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Journal of Cotton Research 2018年第4期1卷 1-11页

作者： WITT Travis W ULLOA mauricio PELLETIER Mathew G. MENDU Venugopal RITCHIE Glen L. Plant and Soil Science Department Texas Tech University USDA-ARS PA CSRL Plant Stress and Germplasm Development Research USDA-ARS Cotton Production and Processing Research Laboratory

Background: Producing rainfed cotton(Gossypium hirsutum L.) with high fiber quality has been challenging in the Texas High Plains because of extended periods of insufficient rainfall during sensitive boll developmental *** variation created by Ethyl MethaneSulfonate(EMS) mutagen has successfully improved fiber quality of cotton. However, little is known about the effect of water deficit environments on fiber quality. Three EMS treated populations were advanced from the first to the fourth generation(M1 to M4) as bulk harvested populations. In2014, single-plant divergent selection was applied based on perceived morphological and agronomic differences seen during and at the end of the ***: Analyses from these selections in 2014-2016 showed significant(P< 0.05) improvement between and within populations for fiber traits(micronaire, length, strength, uniformity, and elongation) when compared with the original non-treated EMS source; some selections were found to have excellent fiber quality under diverse ***: Some of these selections are being considered for germplasm release and could be useful for improving the fiber quality of cotton under water limited conditions, thereby helping to ensure the long-term survival of the cotton industry on the Texas High Plains.

关键词： Breeding Drought EMS Ethyl MethaneSulfonate Fiber quality Selection

Arterial spin labeling in neuroimaging

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World Journal of Radiology 2010年第10期2卷 384-398页

作者： Sasitorn Petcharunpaisan Joana Ramalho mauricio Castillo Division of Neuroradiology University of North Carolina at Chapel HillRoom 3326Old Infirmary BuildingManning DriveChapel HillNC 27599-7510United States Department of Radiology King Chulalongkorn Memorial Hospital1873 Rama IV RoadPathumwanBangkok10330Thailand Department of Neuroradiology Centro Hospitalar de Lisboa CentralEPERua JoséAntónio Serrano1150-199 LisbonPortugal

Arterial spin labeling(ASL) is a magnetic resonance imaging technique for measuring tissue perfusion using a freely diffusible intrinsic *** compared with other perfusion techniques,ASL offers several advantages and is now available for routine clinical practice in many *** noninvasive nature and ability to quantitatively measure tissue perfusion make ASL ideal for research and clinical *** technical advances have increased its sensitivity and also extended its potential *** review focuses on some basic knowledge of ASL perfusion,emerging techniques and clinical applications in neuroimaging.

关键词： Arterial spin labeling Continuous arterial spin labeling Pulsed arterial spin labeling Pseudocontinuous arterial spin labeling Velocity-selective arterial spin labeling Territorial arterial spin labeling Arterial spin labeling at multiple inversion times Perfusion-based functional magnetic resonance imaging

Scientometric Analysis of Research Output from Brazil in Response to the Zika Crisis Using e-Lattes

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Journal of Data and Information Science 2020年第4期5卷 137-146页

作者： Ricardo Barros Sampaio Antônio de Abreu Batista-Jr Bruno Santos Ferreira mauricio LBarreto Jesús PMena-Chalco Regional Board of Brasília Fiocruz Distrito FederalBrazil Department of Informatics Federal University of Maranhão São LuísMABrazil Department of Teaching and Learning Studies Laval UniversityQuébecCanada Center of Integrated Data and Knowledge about Health(CIDACS) SalvadorBrazil Center for Mathematics Computation and CognitionFederal University of ABC Santo AndréSPBrazil

Purpose:This paper aims to test the use of e-Lattes to map the Brazilian scientific output in a recent research health subject:Zika ***/methodology/approach:From a set of Lattes CVs of Zika researchers registered on the Lattes Platform,we used the e-Lattes to map the Brazilian scientific response to the Zika ***:Brazilian science articulated quickly during the public health emergency of international concern(PHEIC)due to the creation of mechanisms to streamline funding of scientific *** limitations:We did not assess any dimension of research quality,including the scientific impact and societal *** implications:e-Lattes can provide useful guidelines for different stakeholders in research groups from Lattes CVs of ***/value:The information included in Lattes CVs permits us to assess science from a broader perspective taking into account not only scientific research production but also the training of human resources and scientific collaboration.

关键词： e-Lattes Zika virus Lattes Platform Brazilian research output Brazilian science

IL28B polymorphisms associated with therapy response in Chilean chronic hepatitis C patients

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World Journal of Gastroenterology 2011年第31期17卷 3636-3639页

作者： mauricio Venegas Rodrigo A Villanueva Katherine González Javier Brahm Centro de Estudios Avanzados de las Hepatitis Virales Sección de GastroenterologíaDepartamento de MedicinaHospital Clínico Universidad de Chile Centro de Estudios Avanzados de las Hepatitis Virales Laboratorio de Virus HepatitisPrograma de VirologíaInstituto de Ciencias BiomédicasFacultad de MedicinaUniversidad de Chile

AIM:To analyze the association of three IL28B single nucleotide polymorphisms with response to therapy in Chilean patients infected with hepatitis C virus ***:We studied two groups of patients with chronic CV infection genotype 1,under standard combined treatment with pegylated interferon plus *** group consisted of 50 patients with sustained virological response,whereas the second group consisted of 49 null *** order to analyze the IL28B single nucleotide polymorphisms rs12979860,rs12980275 and rs8099917,samples were used for polymerase chain reaction amplification,and the genotyping was performed by restriction fragment ***:The IL28B rs12979860 CC,rs12980275 AA and rs8099917 TT genotypes were much more frequently found in patients with sustained virological response compared to null responders 38%,44% and 50% vs 2%,8.2% and 8.2%,*** differences were highly significant in all three cases(P < ***:The three IL28B polymorphisms studied are strongly associated with sustained virological response to therapy in Chilean patients with chronic CV genotype 1.

关键词： IL28B Hepatitis C virus Chile Pegylated interferon Ribavirin

Adequation of a Virtual Immersive Environment for a Learning-Teaching Interaction Using the Limem 3d Method

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通讯和计算机（中英文版） 2015年第2期12卷 57-66页

作者： Diego mauricio Torres Arias Helmuth Trefftz Department of software engineer Universidad EAFIT Department of Computer and Systems Laboratory of Virtual Reality Universidad EAFIT Medellin Colombia

Solar Driven Wind Speed Monitoring System Using Wireless or Wired Sensors

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Energy and Power Engineering 2014年第9期6卷 213-221页

作者： Federico Hahn mauricio Pablo José Reyes Department of Irrigation Universidad Autonoma Chapingo Texcoco México

Instrumented towers are being constructed to characterize vertical wind profiles in order to improve the understanding and characterization of a desired environment up to 100 m. The site being measured is at a height of 2500 m over sea level, in one side of Sierra Madre Oriental, which crosses Mexico from North to South. As the site has no energy, it was powered by a photovoltaic system. Power consumption of two sets of sensors fixed at the tower was evaluated. The first sensor set consisted of a pulsed anemometer and a RH sensor having a 0 - 10 V output;these sensors used cables for transmitting the output signals. Three cup anemometers fixed at 25, 35 and 45 m high measured wind speed. Wireless sensors in the second set, requires of a power consumption and battery life study. Solar cells energized the sensors, becoming the installation and operation easier. The datalogger that acquired the RH and T measurements encountered an 11% voltage loss throughout the cable;cup anemometer measurements did not show variations due to its pulsed signals. Wireless sensors drew less energy from the PV system, resulting in battery overcharge. A dump regulator turned-on a 200 W lamp during the night when the battery voltage reached 14 V;the lamp was turned-off when the battery voltage felt beneath 11.5 V. Considering the high wind available, wireless sensors batteries were charged by small wind turbines combined with 5 W solar panels.

关键词： Wind Tower Wireless Anemometers Battery Regulator

Mechanical properties of nanocomposites reinforced by carbon nanotube sponges

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Journal of Materiomics 2018年第2期4卷 157-164页

作者： Wenjie Zhao Tong Li Yupeng Li Daniel J.O'Brien mauricio Terrones Bingqing Wei Jonghwan Suhr X.Lucas Lu Department of Mechanical Engineering University of DelawareNewarkDE 19716United States Center for Composite Materials University of DelawareNewarkDE 19716United States Weapons and Materials Research Directorate U.S.Army Research LaboratoryAberdeen Proving GroundMD 21005United States Department of Materials Science and Engineering The Pennsylvania State University104 Davey LabUniversity ParkPA 16802-6300United States Department of Physics and Center for 2-Dimensional and Layered Materials The Pennsylvania State University104 Davey LabUniversity ParkPA 16802-6300United States Research Center for Exotic Nanocarbons(JST) Shinshu UniversityWakasato 4-17-1Nagano380-8553Japan School of Mechanical Engineering&Department of Energy Science Sungkyunkwan University300 Chunchun-dongJangan-guSuwon 440-746South Korea

Carbon nanotube(CNT)sponge exhibits unique porous and hierarchical structure that are beneficial to the design of ultralight and tough *** this study,CNT sponges(undoped and boron doped)reinforced polydimethylsiloxane(PDMS)composites were *** properties of the composite,including compressive modulus,rate-dependent modulus,stress relaxation behaviors,dynamic viscoelastic properties,and their dependency on temperature,were systematically investigated.A micromechanical model,Mori-Tanaka model,was validated to describe the mechanical behaviors of CNT sponge reinforced *** coupling with boron-doped CNT sponge,PDMS composites showed remarkable improvement of mechanical properties,including compressive modulus(70%),viscous modulus(243%)and damping capacity(50%).Such reinforcement effects can be controlled by the morphology of CNT sponges,as the boron-doped and undoped nanocomposites showed distinct viscoelastic *** results proved that CNT sponge reinforcement is a promising strategy to develop engineering composites with both outstanding mechanical stiffness and controllable viscoelastic performances.

关键词： Carbon nanotube sponges Nanocomposite Viscoelastic Damping Micromechanics modeling