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Natural selection on flower size in invasive Cytisus scoparius along an elevation gradient

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Journal of Plant Ecology 2020年第2期13卷 165-170页

作者： Robert Frederick Bode Catherine dufresne Department of Natural Sciences College of Arts and SciencesSaint Martin’s UniversityLaceyWA 98503USA

已建群的入侵植物物种在其本地生长范围内比单一种群具有更多样化的基因库。这种遗传和表型变异可以使入侵植物与群落的其他成员相互作用,从而进行自然选择,并形成快速适应机制。对于入侵的开花植物,与传粉者的相互作用可能使其适应异... 详细信息

已建群的入侵植物物种在其本地生长范围内比单一种群具有更多样化的基因库。这种遗传和表型变异可以使入侵植物与群落的其他成员相互作用,从而进行自然选择,并形成快速适应机制。对于入侵的开花植物,与传粉者的相互作用可能使其适应异质性的传粉者群落。入侵地内传粉昆虫群落的变化与本地范围内的变化相似,这表明适应性可能反映了在本地范围内看到的模式。在本论文中,我们研究了在华盛顿州的国会国家森林公园内的一种入侵豆科灌木金雀儿(Cytisus scoparius)花的大小沿海拔梯度的变化。我们在每个样地中测量了10株植物花的宽度和传粉花的比例。我们对沿海拔梯度分布样地的金雀儿在单株水平下的物候变化进行三次测定。研究发现,尽管没有呈现出明显的高海拔具有高选择性的规律,但对于花的大小呈现正选择效应。从授粉昆虫的造访率和种子产量两方面,可以看出自然选择的模式。我们还发现,造成种子产量变化的最大因素不是海拔高度或花的大小,而是管理措施。

关键词：入侵传粉者进化金雀儿属海拔高度

Preparation and Properties of Cellulose Nanomaterials

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Paper And Biomaterials 2020年第3期5卷 1-13页

作者： Alain dufresne UniversitéGrenoble Alpes CNRSGrenoble INPLGP2GrenobleF-38000France

Cellulose is the most abundant biomass material in nature and it is mainly extracted from natural or lignocellulosic *** purification,cellulose fibers exhibit two interesting features for their further transformation into nanomaterials:a hierarchical and multi-level strcture,and a semicrystalline *** forms of cellulose nanomaterials,resulting from a top-down deconstructing strategy(cellulose nanocrystals(CNCs),cellulose nanofibrils(CNFs))or bottom-up strategy(bacterial cellulose(BC))can be *** mechanical shearing actions applied to cellulosic fibers release more or less the nanofibrils individually.A controlled strong acid hydrolysis treatment can be applied to cellulosic fibers allowing dissolution of non-crystalline *** cellulose nanomaterials have been the focus of an exponentially increasing number of works or reviews devoted to understand such materials and their *** have a high potential for an emerging *** the nanoscale,cellulose exhibits specific properties broadening the applications of this naturally occurring *** overview of existing methods for the preparation of cellulose nanomaterials and their specific properties that outperform and contrast with cellulose in the microscale is proposed.

关键词： cellulose nanomaterial nanocrystal nanofibril preparation properties

Mechanism for Src activation by the CCK2 receptor:Patho-physiological functions of this receptor in pancreas

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World Journal of Gastroenterology 2006年第28期12卷 4498-4503页

作者： Audrey Ferrand Sebastien Vatinel Aline Kowalski-Chauvel Claudine Bertrand Chantal Escrieut Daniel Fourmy Marlene dufresne Catherine Seva dufresne Catherine SevaINSERM U 531IFR 31Institut Louis BugnardBP 8422531432 Toulouse cedex 4France

瞄准：调查在活体内， CCK2 受体(CCK2R ) 是否调整蛋白质，知道在房间增长和癌症开发和分析在试管内起一个关键作用导致 Src 激活的分子的机制；特别地，那在这激活被含有在 CCK2R 顺序以内识别领域。方法：Src 和英皇家空军之阶级最... 详细信息

瞄准：调查在活体内， CCK2 受体(CCK2R ) 是否调整蛋白质，知道在房间增长和癌症开发和分析在试管内起一个关键作用导致 Src 激活的分子的机制；特别地，那在这激活被含有在 CCK2R 顺序以内识别领域。方法：Src 和英皇家空军之阶级最低之兵的表示和激活是学习在活体内使用免疫荧光和西方污点的技术。我们使用了从在胰腺的腺泡表示了 CCK2R 的野类型或 Elas-CCK2 老鼠导出的胰腺的纸巾，显示了增加的胰腺的生长并且开发了肿瘤前损害。短暂地表示内长的 CCK2R 或 COS-7 房间的胰腺的肿瘤房间线 AR4-2J 有野类型或变异的 CCK2R 的 transfected 被用作在试管内模型学习 Src 激活的机制。Src 激活被在试管内激酶试金测量，由用 anti-phospho-ERK 抗体和在由 MTT 的导致 gastrin 的房间增长的 Src 的参与的西方的污点的英皇家空军之阶级最低之兵激活测试。结果：我们出现了因为在 Elas-CCK2 鼠标的胰的指向的 CCK2R 表达式，导致了 Src 和 ERK 小径的激活。Src 被激活由在胰腺的弦音器的 CCK2R 的 ERK 小径在上游口头的房间并且贡献了增生的效果由这受体调停了。在试管内结果证明由 CCK2R 的 Src/ERK 小径的激活要求了 NPXXY 主题，在第 7 transmembrane 领域的结束在 CCK2R 顺序以内定位了，并且建议了在这机制的 Gq 的通常认为的角色。结论：由 CCK2R 的 Src/ERK 小径的解除管制可能代表贡献房间增长，肿瘤前损害的形成和胰腺的肿瘤开发的早步。

关键词：受体胰腺疾病细胞活化胃泌激素

Orchestration of occludins, claudins, catenins and cadherins as players involved in maintenance of the blood-epididymal barrier in animals and humans

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Asian Journal of Andrology 2007年第4期9卷 463-475页

作者： Daniel G. Cyr Mary Gregory Evemie Dube Julie dufresne Peter T. K. Chan Louis Hermo INRS-Institut Armand Frappier Universite du Quebec 245 Hymus Boulevard Pointe Claire QC H9R 1G6 Canada Department of Urology Royal Victoria Hospital McGill University Montreal QC H3A 1A1 Canada Department of Anatomy and Cell Biology McGill University Montreal QC H3A 2B2 Canada

Although spermatozoa are formed during spermatogenesis in the testis, testicular spermatozoa are immature and cannot swim or fertilize. These critical spermatozoal functions are acquired in the epididymis where a specific luminal environment is created by the blood-epididymal barrier; proteins secreted by epididymal principal cells bind to maturing spermatozoa and regulate the maturational process of the spermatozoa. In the epididymis, epithelial cell-cell interactions are mediated by adhering junctions, necessary for cell adhesion, and by tight junctions, which form the blood-epididymal barrier. The regulation of these cellular junctions is thought to represent a key determinant in the process of sperm maturation within the epididymis. Tight junctions between adjacent principal cells permit the formation of a specific microenvironment in the lumen of the epididymis that is essential for sperm maturation. Although we have made significant progress in understanding epididymal function and the blood-epididymal barrier, using animal models, there is limited information on the human epididymis. If we are to understand the normal and pathological conditions attributable to human epididymal function, we must clearly establish the physiological, cellular and molecular regulation of the human epididymis, develop tools to characterize these functions and develop clinical strategies that will use epididymal functions to improve treatment of infertility. （Asian J Androl 2007 July; 9： 463- 475）

关键词： claudins cadherins catenins human rat mouse tight junction adherens junction

Isolation and Characterization of Cellulose Nanofibers from Argentine Tacuara Cane(Guadua Angustifolia Kunth)

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Journal of Renewable Materials 2019年第4期7卷 373-381页

作者： C.A.Rodríguez Ramírez Fleur Rol Julien Bras Alain dufresne Nancy Lis Garcia Norma D'Accorso Universidad de Buenos Aires Facultad de Ciencias Exactas y NaturalesDepartamento de Química OrgánicaBuenos Aires Argentina CONICET-Universidad de Buenos Aires.Centro de Investigación en Hidratos de Carbono(CIHIDECAR).Buenos Aires Argentina Univ.Grenoble Alpes CNRSGrenoble INPLGP2F-38000France

New trends in the area of material improvement are the use of natural nano-charges from renewable biomass,improving the value and sustainability of our country’s natural *** is widely used in many countries of the world,although in Argentina,despite being commercialized and exported for the manufacture of wood floors,it goes unnoticed despite having native ***,researchers identified the native and exotic species present in our country and are working on novel *** this context,it is proposed the Argentine Tacuara Cane(Guadua Angustifolia Kunth),endemic plant as a new source of nanocellulosic materials,where stem fibers have been isolated using a green method achieving with yield of 45.9%of *** cellulose nanofibrils(CNF)were obtained using a green homogenization *** CNF exhibited web-like long fibrous structure with the diameter of 10-20 *** crystallinity was 65.5%,as for the onset temperature of thermal decomposition was 212°*** nanocellulose isolated from the Tacuara Cane seed fibers has a high potential to be used as a new source of cellulose-based nanofiller for the reinforcement of bionanocomposite films.

关键词： Cellulose nanofibers green valorization

Norine: A powerful resource for novel nonribosomal peptide discovery

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Synthetic and Systems Biotechnology 2016年第2期1卷 89-94页

作者： M.Pupin Q.Esmaeel A.Flissi Y.dufresne P.Jacques V.Leclère Univ Lille CNRSCentrale LilleUMR 9189-CRIStAL-Centre de Recherche en Informatique Signal et Automatique de LilleF-59000 LilleFrance Inria-Lille Nord Europe Villeneuve d’Ascq Cedex F-59655France Univ Lille INRAISAUniv ArtoisUniv Littoral Coce d’OpaleEA 7394-ICV-Institut Charles ViolletteF-59000 LilleFrance Bioindustry Unit Gembloux Agro-Bio Tech-University of LiegePassage des Déportés2Gembloux 5030Belgium

Since its first release in 2008,Norine remains the unique resource completely devoted to nonribosomal peptides(NRPs).They are very attractive microbial secondary metabolites,displaying a remarkable diversity of structure and ***(http://***/NRP)includes a database now containing more than 1160 annotated peptides and user-friendly interfaces enabling the querying of the database,through the annotations or the structure of the *** tools are associated for structural comparison of the compounds and prediction of their biological *** this paper,we start by describing the knowledgebase and the dedicated *** then present some user cases to show how useful Norine is for the discovery of novel nonribosomal peptides.

关键词： Norine Nonribosomal peptides Secondary metabolites Database

Robotic pendant drop:containerless liquid for μs-resolved,AI-executable XPCS

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Light(Science & Applications) 2023年第9期12卷 1857-1866页

作者： Doga Yamac Ozgulbas Don Jensen Jr. Rory Butler Rafael Vescovi Ian T.Foster Michael Irvin Yasukazu Nakaye Miaoqi Chu Eric M.dufresne Soenke Seifert Gyorgy Babnigg Arvind Ramanathan Qingteng Zhang Data Science and Learning Division Argonne National LaboratoryLemontIL 60439USA X-ray Science Division Argonne National LaboratoryLemontIL 60439USA Departement of Computer Science University of Chicago5801 S Ellis AveChicagoIL 60637USA XRD Design and Engineering Department Rigaku Corporation 3-9-12 Matsubara-choAkishima-shiTokyo 196-8666Japan Bioscience Division Argonne National LaboratoryLemontIL 60439USA

The dynamics and structure of mixed phases in a complex fluid can significantly impact its material properties,such as ***-angle X-ray Photon Correlation Spectroscopy(SA-XPCS)can probe the spontaneous spatial fluctuations of the mixed phases under various in situ environments over wide spatiotemporal ranges(10−6–103 s/10−10–10−6 m).Tailored material design,however,requires searching through a massive number of sample compositions and experimental parameters,which is beyond the bandwidth of the current coherent X-ray *** 3.7-μs-resolved XPCS synchronized with the clock frequency at the Advanced Photon Source,we demonstrated the consistency between the Brownian dynamics of~100 nm diameter colloidal silica nanoparticles measured from an enclosed pendant drop and a sealed *** electronic pipette can also be mounted on a robotic arm to access different stock solutions and create complex fluids with highly-repeatable and precisely controlled composition *** closed-loop,AI-executable protocol is applicable to light scattering techniques regardless of the light wavelength and optical coherence,and is a first step towards high-throughput,autonomous material discovery.

关键词： resolved sealed mounted

Communication Mediated through Natural Language Generation in Big Data Environments: The Case of Nomao

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Journal of Computer and Communications 2017年第6期5卷 125-148页

作者： Jean-Sébastien Vayre Estelle Delpech Aude dufresne Céline Lemercier CERTOP (UMR-5044) University of Toulouse Jean Jaurès Toulouse France Human Factors Airbus Blagnac France LRCM University of Montréal Montréal Québec CLLE (UMR-5263) University of Toulouse Jean Jaurès Toulouse France

Along with the development of big data, various Natural Language Generation systems (NLGs) have recently been developed by different companies. The aim of this paper is to propose a better understanding of how these systems are designed and used. We propose to study in details one of them which is the NLGs developed by the company Nomao. First, we show the development of this NLGs underlies strong economic stakes since the business model of Nomao partly depends on it. Then, thanks to an eye movement analysis conducted with 28 participants, we show that the texts generated by Nomao’s NLGs contain syntactic and semantic structures that are easy to read but lack socio-semantic coherence which would improve their understanding. From a scientific perspective, our research results highlight the importance of socio-semantic coherence in text-based communication produced by NLGs.

关键词： Big Data Natural Language Generation Socio-Semantic Coherence Cognitive Load Reading Eye Tracking

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再生纤维素补强天然橡胶的研究

再生纤维素补强天然橡胶的研究