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Chemical-assisted MMP reduction on methane-oil systems:Implications for natural gas injection to enhanced oil recovery

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Petroleum 2024年第1期10卷 101-108页

作者： Mohamed Almobarak matthew b.myers Colin D.Wood Yongbing Liu Ali Saeedi Quan Xie Discipline of Petroleum Engineering WA School of Mines:MineralsEnergy and Chemical EngineeringCurtin UniversityWestern AustraliaAustralia Commonwealth Scientific and Industrial Research Organization Kensington6151Australia Curtin University Oil and Gas Innovation Centre Management Kensington6151Australia State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation No.8 Xindu AvenueXindu DistrictChengdu 610500PR China

***,the main challenge in this process is the high minimum miscibility pressure(MMP)between natural gas and crude oil,which limits its application and recovery factor,especially in hightemperature ***,we present a novel investigation to quantify the effect of chemicalassisted MMP reduction on the oil recovery ***,we measured the interfacial tension(IFT)of the methane-oil system in the presence of chemical or CO_(2) to calculate the MMP reduction at a constant temperature(373K)using the vanishing interfacial tension(VIT)***,we performed three coreflooding experiments to quantify the effect of MMP reduction on the oil recovery factor under different injection *** interfacial tension measurements show that adding a small fraction(1.5 wt%)of the tested surfactant(SOLOTERRA ME-6)achieved 9%of MMP reduction,while adding 20 wt%of CO_(2) to the methane yields 13%of MMP ***,the coreflooding results highlight the significance of achieving miscibility during gas injection,as the ultimate recovery factor increased from 65.5%under immiscible conditions to 77.2%using chemical-assisted methane,and to 79%using gas mixture after achieving near miscible *** results demonstrate the promising potential of the MMP reduction to signifi-cantly increase the oil recovery factor during gas ***,these results will likely expand the application envelop of the miscible gas injection,in addition to the environmental benefits of utilizing the produced gas by re-injection/recycling instead of flaring which contributes to reducing the greenhouse gas emissions.

关键词： Gas injection Enhanced oil recovery Miscibility Coreflooding

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Direct Pointwise Comparison of FE Predictions to StereoDIC Measurements:Developments and Validation Using Double Edge-Notched Tensile Specimen

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1263-1298页

作者： Troy myers Michael A.Sutton Hubert Schreier Alistair Tofts Sreehari Rajan Kattil Department of Mechanical Engineering University of South CarolinaColumbiaSC29208USA Correlated Solutions Incorporated 121 Dutchman BlvdColumbiaSC29063USA

To compare finite element analysis(FEA)predictions and stereovision digital image correlation(StereoDIC)strain measurements at the same spatial positions throughout a region of interest,a field comparison procedure is *** procedure includes(a)conversion of the finite element data into a triangular mesh,(b)selection of a common coordinate system,(c)determination of the rigid body transformation to place both measurements and FEA data in the same system and(d)interpolation of the FEA nodal information to the same spatial locations as the StereoDIC measurements using barycentric *** an aluminum Al-6061 double edge notched tensile specimen,FEA results are obtained using both the von Mises isotropic yield criterion and Hill’s quadratic anisotropic yield criterion,with the unknown Hill model parameters determined using full-field specimen strain measurements for the nominally plane stress *** Hill’s quadratic anisotropic yield criterion,the point-by-point comparison of experimentally based full-field strains and stresses to finite element predictions are shown to be in excellent agreement,confirming the effectiveness of the field comparison process.

关键词： StereoDIC spatial co-registration data transformation finite element simulations point-wise comparison of measurements and FEA predictions double edge notch specimen model validation

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Oral transforming growth factor-beta receptor 1 inhibitor vactosertib promotes osteosarcoma regression by targeting tumor proliferation and enhancing anti-tumor immunity

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Cancer Communications 2024年第8期44卷 884-888页

作者： Sung Hee Choi Jay Thomas myers Suzanne Louise Tomchuck Melissa bonner Saada Eid Daniel Tyler Kingsley Kristen Ashley Van Heyst Seong-Jin Kim byung-Gyu Kim Alex Yee-Chen Huang Department of Pediatrics CaseWestern Reserve University School of MedicineClevelandOhioUSA Case Comprehensive Cancer Center CaseWestern Reserve University School of MedicineClevelandOhioUSA Department of Pathology CaseWestern Reserve University School of MedicineClevelandOhioUSA MedPacto Inc. SeoulRepublic of Korea Center for Pediatric Immunotherapy Angie Fowler AYA Cancer InstituteUH Rainbow Babies and Children’s HospitalClevelandOhioUSA

Osteosarcoma is an aggressive malignant bone sarcoma common among children,adolescents,and young *** 20%of patients present with pulmonary metastasis,and an additional 40%develop pulmonary osteosarcoma *** survival ou... 详细信息

关键词： osteosarcoma immunity patients

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马克思与虚无主义问题

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现代哲学 2011年第2期 18-24页

作者： David b.myers[美] 邓先珍(译) 美国Moorhead州立大学中山大学马克思主义哲学与中国现代化研究所、哲学系广州510275

马克思的目的是要说明人对价值的需要无须超越历史就能得到满足。认为善(good)内在于历史上与断言善是与历史相同的并非一回事。马克思并不是一个历史主义者——如罗森所使用的术语——因为他没有把善与"所发生之事"等同起来。罗森认为... 详细信息

马克思的目的是要说明人对价值的需要无须超越历史就能得到满足。认为善(good)内在于历史上与断言善是与历史相同的并非一回事。马克思并不是一个历史主义者——如罗森所使用的术语——因为他没有把善与"所发生之事"等同起来。罗森认为,马克思必定主张在历史中发生的任何事情都是可允许的。马克思的标准是人,而不是历史中在马克思的特定意义上算作人类的(行动)的所有行动。实际上在历史进程中,绝大多数个体是以一种非人的方式把自己对象化的。这就是马克思把前共产主义时期描述为"前历史"的原因,因为那是这样一段时间,在其中社会存在是人类活动的无意识的产物。只有当诸个体自觉地决定其生活并把物质世界置于合作性控制之下,恰当意义上的历史才真正开始。

关键词：马克思虚无主义施蒂纳罗森

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企业在渠道多元化后……

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中外管理 2005年第10期 42-44页

作者： Joseph b.myers Andrew D．Pickersgill Evan S．Van Metre

曾几何时，企业只需要一个渠道就可以向客户提供所有产品和服务。但如今，为了满足客户对更多渠道的需求，企业已纷纷开拓多种与客户接触途径。通常，客户使用多种渠道会比只用一种渠道平均多消费20％～30％，而且像互联网和海外电话中... 详细信息

曾几何时，企业只需要一个渠道就可以向客户提供所有产品和服务。但如今，为了满足客户对更多渠道的需求，企业已纷纷开拓多种与客户接触途径。通常，客户使用多种渠道会比只用一种渠道平均多消费20％～30％，而且像互联网和海外电话中心这样的渠道还可以节约大量成本。

关键词：企业渠道多元化经营管理客户忠诚度服务成本

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Physiological and Growth Responses of C_3 and C_4 Plants to Reduced Temperature When Grown at Low CO_2 of the Last Ice Age

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Journal of Integrative Plant biology 2008年第11期50卷 1388-1395页

作者： Joy K.Ward David A.myers Richard b.Thomas Department of Ecology and Evolutionary biology University of Kansas Department of biology West Virginia University

During the last ice age, CO2 concentration （[CO2]） was 180-200 umol/mol compared with the modern value of 380 umol/mol, and global temperatures were -8 ℃ cooler. Relatively little is known about the responses of C3 and C4 species to longterm exposure to glacial conditions. Here Abutilon theophrasti Medik. （C3） and Amaranthus retroflexus L. （C4） were grown at 200 umol/mol CO2 with current （30/24℃） and glacial （22/16℃） temperatures for 22d. Overall, the C4 species exhibited a large growth advantage over the C3 species at low [CO2]. However, this advantage was reduced at low temperature, where the C4 species produced 5x the total mass of the C3 species versus 14x at the high temperature. This difference was due to a reduction in C4 growth at low temperature, since the C3 species exhibited similar growth between temperatures. Physiological differences between temperatures were not detected for either species, although photorespiration/net photosynthesis was reduced in the C3 species grown at low temperature, suggesting evidence of improved carbon balance at this treatment. This system suggests that C4 species had a growth advantage over C3 species during low [CO2] of the last ice age, although concurrent reductions in temperatures may have reduced this advantage.

关键词： Abutilon theophrasti Amaranthus retroflexus C3 species C4 species climate change low CO2 low temperature photorespiration Pleistocene.

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天生不同

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作者： (美)伊莎贝尔·迈尔斯(Isabel briggs myers) (美)彼得·迈尔斯(Peter b.myers)

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Is Alzheimer’s Disease an Adaptability Disorder? What Role Does Happiness Have in Treatment, Management and Prevention

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World Journal of Neuroscience 2015年第3期5卷 180-188页

作者： John b. myers Wellspring’s Universal Environment P/L Melbourne Australia

A case presentation indicating the importance of “happiness” in childhood causing memory block until the patent presented with probable mixed vascular and neurodegenerative memory loss at 60 years of age is presented to highlight the role of emotional factors in causing the disease. The question of whether Alzheimer’s disease is an adaptability disorder is raised, given the patient blocked out her memory of her childhood experience. The importance of “happiness” as a treatment goal raises issues of advocacy and Guardianship as well as capacity, which is addressed by actual case reference and court action in defence of the patient’s rights to have their wishes respected and observed. Functional mental capacity assessment, using the Functional Mental State Measure (FMSM) gives a greater indication of neuronal reserve than standard cognitive testing, as it helps to unravel the dilemma associated with pure cognitive assessment in Alzheimer’s Disease as well as vascular dementia patients and patients who, despite retained and intact functional capacity and ability to express their wishes, i.e. “best interest”, are “wrongly” placed under Guardianship. Maladaptive responses, to control the change in external environment that are sensed or perceived, and which lead to disorder or to susceptibility to disease, exemplify a General Systems Theory approach, in which appropriate and adequate responses to environmental change, in behavioural terms, by a person, whether independently, or as the recipient or giver, or both, leads to functional interaction and happiness.

关键词： Alzheimer’s Disease Vascular Dementia “Happiness as a Goal Cause and in Management” Functional Mental Capacity Memory Cognitive Development Advocacy behaviour General Systems Theory

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Erratum to “Is Alzheimer’s Disease an Adaptability Disorder? What Role Does Happiness Have in Treatment, Management and Prevention” [World Journal of Neuroscience 5 (2015) 180-188]

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World Journal of Neuroscience 2015年第4期5卷 292-301页

作者： John b. myers Wellspring’s Universal Environment P/L Melbourne Australia

A case presentation indicating the importance of “happiness” in childhood causing memory block until the patent presented with probable mixed vascular and neurodegenerative memory loss at 60 years of age is presented to highlight the role of emotional factors in causing the disease. The question of whether Alzheimer’s disease is an adaptability disorder is raised, given the patient blocked out her memory of her childhood experience. The importance of “happiness” as a treatment goal raises issues of advocacy and Guardianship as well as capacity, which is addressed by actual case reference and court action in defence of the patient’s rights to have their wishes respected and observed. Functional mental capacity assessment, using the Functional Mental State Measure (FMSM) gives a greater indication of neuronal reserve than standard cognitive testing, as it helps to unravel the dilemma associated with pure cognitive assessment in Alzheimer’s Disease as well as vascular dementia patients and patients who, despite retained and intact functional capacity and ability to express their wishes, i.e. “best interest”, are “wrongly” placed under Guardianship. A General Systems approach, which recognises functional interaction as optimal and withdrawal or inadequate and/or inappropriate response as not, provides further understanding of the relationship between emotional factors, memory and neurodegenerative (Alzheimer’s) disease.

关键词： Alzheimer’s Disease Vascular Dementia “Happiness as a Goal Cause and in Management” Functional Mental Capacity Memory Advocacy behaviour General Systems Theory

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Function and regulation of self-reactive marginal zone b cells in autoimmune arthritis

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Cellular & Molecular Immunology 2015年第4期12卷 493-503页

作者： Anna-Karin E Palm Heike C Friedrich Anja Mezger Maya Salomonsson Linda K myers Sandra Kleinau Department of Cell and Molecular biology Uppsala University Uppsala Sweden Department of Pediatrics University of Tennessee Health ScienceCenter Memphis TN USA

Polyreactive innate-type b cells account for many b cells expressing self-reactivity in the periphery. Improper regulation of these b cells may be an important factor that underlies autoimmune disease. Here we have explored the influence of self-reactive innate b cells in the development of collagen-induced arthritis （CIA）, a mouse model of rheumatoid arthritis. We show that splenic marginal zone （MZ）, but not b- 1 b cells exhibit spontaneous IgM reactivity to autologous collagen II in na＇=＇ve mice. Upon immunization with heterologous collagen II in complete Freund＇s adjuvant the collagen-reactive MZ b cells expanded rapidly, while the b-1 b cells showed a modest anti-collagen response. The MZ b cells were easily activated by toll-like receptor （TLR） 4 and 9-1igands in vitro, inducing proliferation and cytokine secretion, implying that dual engagement of the b-cell receptor and TLRs may promote the immune response to self-antigen. Furthermore, collagen-primed MZ b cells showed significant antigen-presenting capacity as reflected by cognate T-cell proliferation in vitroand induction of IgG anti-collagen antibodies in vivo. MZ b cells that were deficient in complement receptors I and 2 demonstrated increased proliferation and cytokine production, while Fcy receptor lib deficiency of the cells lead to increased cytokine production and antigen presentation. In conclusion, our data highlight self-reactive MZ b cells as initiators of the autoimmune response in CIA, where complement and Fc receptors are relevant in controlling the self-reactivity in the cells.

关键词： arthritis complement receptors Fc receptors marginal zone b cells, mice

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