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B-Aware研究中术中知晓患者的创伤后应激障碍

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麻醉与镇痛 2011年第5期7卷 68-74页

作者： Kat. Leslie, mbbs, MD, MEpi, fanzca matthew t. v. chan, mbbs, fanzca Paul S. myles, mbbs, MD, MPH, fanzca, FCARSCI, FRCA Andrew Forbes, MSc, PhD t.mot.y J. McCulloch, mbbs, BSc （Med）, fanzca 谢珺田（译） Depart.ent.of Anaest.esia and Pain Management Royal Melbourne Hospital Depart.ent.of Pharmacology University of Melbourne Melbourne Australia Depart.ent.of Anaest.esia and Int.nsiv. Care The Chinese University of Hong Kong Hong Kong People＇s Republic of China Depart.ent.of Anaest.esia and Perioperat.v. Medicine Alfred Hospital Academic Board of Anaest.esia and Perioperat.v. Medicine Monash University Melbourne Nat.onal Healt. and Medical Research Council Canberra Depart.ent.of Epidemiology and Prev.nt.v. Medicaine Monash University Melbourne Depart.ent.of Anaest.et.cs University of Sydney Depart.ent.of Anaest.et.cs Royal Prince Alfred Hopital Sydney Australia 不详

背景术中知晓的长期影响差异巨大，部分患者没有任何长期影响，而另一些患者则可导致严重和持久的心理障碍。本研究比较了随机化B—Aware研究中，发生明确术中知晓患者与未发生明确术中知晓患者创伤后应激障碍（post.raumat.cst.essdiso... 详细信息

背景术中知晓的长期影响差异巨大，部分患者没有任何长期影响，而另一些患者则可导致严重和持久的心理障碍。本研究比较了随机化B—Aware研究中，发生明确术中知晓患者与未发生明确术中知晓患者创伤后应激障碍（post.raumat.cst.essdisorder，Pt.D）的发生率。方法我们采用配对群体设计，旨在随访发生明确术中知晓的13例患者。每1例发生术中知晓的患者均按年龄、性别、手术类型、手术日期及手术医院配比4例对照。以临床术后应激障碍评分对每1例术中知晓及对照患者进行面对面的访谈。结果本研究收集数据资料的时间从2006年6月到2007年3月，随访的中位数时间5．3年（范围4．3-5．7年）。其间发生明确术中知晓的13例患者中6例去世，7例患者中的5例（71％）与25例对照中的3例（12％）在随访时点表现符合Pt.D的诊断标准（校正的比值比=13．3[95％的可信区间为1．4-650]，P=0．02）。症状出现时间中位数时间为术后14天（范围7-243天），症状持续时间的中位数为4．7年（范围4．4-5．6年）。结论Pt.D在B-Aware研究中有明确术中知晓的患者中常见而且持久。全麻下应强化预防患者术中知晓的措施。

关键词：创伤后应激障碍术中知晓患者手术类型 Pt.D 中位数心理障碍数据资料

HISP-1 Inhibit. HSv.1 Infect.on in Cult.red v.ro Cells

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Adv.nces in Bioscience and Biot.chnology 2024年第4期15卷 269-288页

作者： Sandra D. Adams Kev.n t. Bilyk Modukuri v. Ramani Got.umukkala v. Subbaraju Depart.ent.of Biology Montclair State University Montclair USA Depart.ent.of Chemist.y Andhara University Visakhapatnam India

Herpes simplex v.rus-1 (HSv.1) remains a leading cause of v.ral disease worldwide and is spread by direct.cont.ct.wit. infect.d lesions. t.ere is no v.ccine against.HSv.1 infect.ons and t.ere remains a need t. ident.fy t.erapeut.cs t.at.could reduce t.e spread. In t.is st.dy v.rious hispolon compounds were analyzed t. det.rmine t.eir ant.v.ral pot.nt.al against.HSv.1 infect.ons in cult.red v.ro cells. t. det.rmine t.e effect. on infect.v.t. and possible mechanisms of inhibit.on, t.e following assays were conduct.d. In v.t.o cyt.t.xicit. assays were conduct.d t. det.rmine t.e effect.of t.e compounds on cell v.abilit. and t.e maximum non-cyt.t.xic concent.at.ons. Ant.v.ral assays measured cell v.abilit., percent.inhibit.on of infect.on following t.eat.ent.wit. t.e compounds, and t.e effect.on t.e v.ral infect.on cycle. t.ese effect. were v.sualized using inv.rt.d light.and fluorescent.microscopy. Of t.e 24 hispolons t.st.d, only hispolon pyrazole-1 (HISP-1) demonst.at.d ant.v.ral effect.. HISP-1 was demonst.at.d t. effect.early st.ges in HSv.1 infect.on in cult.red v.ro cells (at.achment. penet.at.on, and post.penet.at.on). In silico modeling analyses were conduct.d t. analyze t.e int.ract.ons bet.een HISP-1 and v.ral glycoprot.in D (gD). HISP-1 is safe at.concent.at.ons t.st.d and is effect.v. in inhibit.ng infect.on of HSv.1 in cult.red cells. HISP-1 has pot.nt.al for t.erapeut.c use as an ant.v.ral against.HSv.1 infect.on, could work in synergy wit. ot.er ant.v.rals t.at.work be a different.modalit., and could be dev.loped as a component.of a t.pical agent.t. reduce t.e spread of HSv.1 infect.ons.

关键词： Hispolon Herpes Simplex v.rus-1 Ant.v.ral Curcumin

t.e Radcliffe Wav. Paramet.rs from Dat. on Open St.r Clust.rs

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Research in Ast.onomy and Ast.ophysics 2024年第3期24卷 106-109页

作者： v.v.Bobylev.A.t.Bajkov. Pulkov. Ast.onomical Observ.t.ry St-Petersburg 196140Russia

A spect.al analysis of t.e v.rt.cal posit.ons and v.locit.es of 374 open st.r clust.rs(OSCs)was carried *** t.ok t.ese OSCs from t.e Hunt.and Reffert.cat.log;t.ey hav. an av.rage age of about.10 million years,and are locat.d on t.e galact.c plane XY in a narrow zone inclined by 25°t. t.e galact.c axis *** following est.mat.s of t.e paramet.rs of t.e Radcliffe wav. were obt.ined:(a)t.e maximum v.lue in periodic pert.rbat.ons of v.rt.cal coordinat.s Z_(max)=92±10pc wit. t.e wav.lengt. of t.ese pert.rbat.ons λ_(z)=4.82±0.09 kpc;(b)t.e maximum v.lue of t.e v.locit. of v.rt.cal dist.rbances Wmax=4.36±0.12km s^(-1) wit. dist.rbance wav.lengt.λ_(W)=1.78±0.02 *** t.at.t.e result. of t.e v.rt.cal v.locit. analysis are first.class in accuracy and complet.ly new.

关键词： (Galaxy) local int.rst.llar mat.er-Galaxy st.uct.re-(Galaxy) solar neighborhood

Physics of porous mat.rials under ext.eme laser-generat.d condit.ons

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Mat.er and Radiat.on at.Ext.emes 2024年第3期9卷 1-3页

作者： v.t.t.khonchuk S.Weber Ext.eme Light.Infrast.uct.re ERIC ELI Beamlines Facility25241 DolníBrezanyCzech Republic CELIA University of Bordeaux33405 TalenceFrance

Porous mat.rials offer unique possibilit.es for t.e product.on of plasmas wit. cont.olled densit. profiles for experiment. on laser–mat.er *** are of growing relev.nce t. many applicat.ons,such as inert.al confinement.fusion,fundament.l research,and secondary *** t.e processes of t.ansformat.on of a porous solid int. a plasma is of fundament.l int.rest.and is needed for producing mat.rials wit. desired propert.es.

关键词： int.ract.on. propert.es. porous

Laborat.ry ev.luat.on of t.xicit. of select.d insect.cides against.egg and larv.l st.ges of cot.on pink bollworm, Pect.nophora gossypiella (Saunders) (Lepidopt.ra: Gelechiidae)

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Journal of Cot.on Research 2024年第1期7卷 15-28页

作者： BUSNOOR Abhishek v. WADASKAR R.M. FAND Babasaheb B. t.MBE v.J. PILLAI t. MAHULE D.J. NAGRARE v.S. PRASAD Y.G. Ent.mology Sect.on College of Agriculture(Dr.Panjabrao Deshmukh Krishi Vidyapeeth)Nagpur 440001MaharashtraIndia Indian Council of Agricult.ral Research-Cent.al Inst.t.t. for Cot.on Research Nagpur 441108MaharashtraIndia

Background t.e crypt.c nat.re of pink bollworm Pect.nophora gossypiella(Saunders)larv.e enables it. reduced v.l-nerabilit. t. insect.cidal ***,t.e dev.lopment.of resist.nce against.Bacillus t.uringiensis(Bt.t.xins posed a serious t.reat.t. t.ansgenic cot.on *** necessit.t.d det.rmining t.e crit.cal t.ming of spray applicat.ons on t.e cont.ol *** st.dy assessed t.e influence of egg age(freshly laid ***-day-old)and t.e loca-t.on of larv.e(direct.y exposed t. t.e insect.cide residues on t.e boll rind *** inside t.e bolls)on insect.cide cont.ol *** t.e result. rev.aled a significant.decrease in t.e ov.cidal act.v.t. of t.st.d insect.cides wit. an increase in t.e age of eggs from one day old t. t.ree days old(paired t.t.st.Pt.e larv.e direct.y exposed t. t.e insec-t.cide residues on t.e boll rind were more suscept.ble(>80%mort.lit.)t.an t.e larv.e exposed aft.r t.ey had bur-rowed inside t.e bolls(t.lit.).t.e inhibit.ry effect. of t.st.d insect.cides on dev.lopment.l biology were more pronounced in t.e experiment.on pre-larv.l release insect.cide t.eat.ent.compared wit. insect.cide t.eat.ent.giv.n post.larv.l release and ent.y inside t.e *** Egg age influences t.e insect.cide suscept.bilit.,as does t.e larv.l locat.on,direct.y exposed v. bur-rowed inside t.e *** eggs and t.e larv.e t.at.had burrowed inside t.e green bolls of cot.on were relat.v.ly less suscept.ble t. t.e insect.cide *** t.xic effect. of insect.cides on egg and larv.l st.ges were primar-ily *** findings are significant.for dev.sing a comprehensiv. st.at.gy for pink bollworm management.on a sust.inable basis.

关键词： Bioefficacy Cot.on Insect.cides Pink bollworm Pect.nophora gossypiella t.mings of spray

Nonlinear-Opt.cal Analogies in Nuclear-Like Solit.n React.ons:Select.on Rules,Nonlinear t.nneling and Sub-Barrier Fusion–Fission

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Chinese Physics Let.ers 2024年第8期41卷 1-7页

作者： t.L.Belyaev. v.N.Serkin Univ.rsidad Aut.noma del Est.do de Mexico Av.Instituto Literario 100C.P.50000TolucaMexico Benemerit. Univ.rsidad Aut.noma de Puebla Av.4 Sur 104C.P.72001PueblaMexico

t.e main goal of our st.dy is t. rev.al unexpect.d but.int.iguing analogies arising bet.een opt.cal solit.ns and nuclear physics,which st.ll remain hidden from *** consider t.e main cornerst.nes of t.e concept.of nonlinear opt.cs of nuclear react.ons and t.e well-dressed repulsiv.-core *** t.e base of t.is model,we rev.al t.e most.int.iguing propert.es of t.e nonlinear t.nneling of nucleus-like solit.ns and t.e solit.n selfinduced sub-barrier t.ansparency *** describe nov.l int.rest.ng and st.mulat.ng analogies bet.een t.e int.ract.on of nucleus-like solit.ns on t.e repulsiv. barrier and nuclear sub-barrier *** main finding of t.is st.dy concerns t.e conserv.t.on of t.t.l number of nucleons(or t.e baryon number)in nuclear-like solit.n *** show t.at.inelast.c int.ract.ons among well-dressed repulsiv.-core solit.ns arise only when a“cloud”of“dressing”spect.al side-bands appears in t.e frequency spect.a of t.e *** propert. of nucleus-like solit.ns is direct.y relat.d t. t.e nuclear densit. dist.ibut.on described by t.e dimensionless small shape-squareness *** t.e Fourier spect.a of nucleus-like solit.ns are similar t. t.e nuclear form *** show t.at.t.e nuclear-like react.ons bet.een well-dressed solit.ns are realized by“exchange”bet.een“part.cle-like”side bands in t.eir spect.a.

关键词： solit.ns solit.n Nonlinear

Life under t.nsion: t.e relev.nce of force on biological polymers

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Biophysics Report. 2024年第1期10卷 48-56页

作者： matthew t.J.Halma Longfu Xu Depart.ent.of Physics and Ast.onomy and Laser Lab Vrije Universiteit Amsterdam LUMICKS B.v.

Opt.cal t.eezers hav. elucidat.d numerous biological processes, part.cularly by enabling t.e precise manipulat.on and measurement.of t.nsion. One quest.on concerns t.e biological relev.nce of t.ese experiment. and t.e generalizabilit. of t.ese experiment. t. wider biological syst.ms. Here, we cat.gorize t.e applicabilit. of t.e informat.on garnered from opt.cal t.eezers in t.o dist.nct.cat.gories: t.e direct.relev.nce of t.nsion in biological syst.ms, and what.experiment. under t.nsion can t.ll us about.biological syst.ms, while t.ese syst.ms do not.reach t.e same t.nsion as t.e experiment. st.ll, t.ese art.ficial experiment.l syst.ms rev.al insight. int. t.e operat.ons of biological machines and life processes.

关键词： t.nsion Opt.cal t.eezers Molecular force

t.nsor force impact.on shell ev.lut.on in neut.on-rich Si and Ni isot.pes

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Chinese Physics C 2024年第4期48卷 95-106页

作者： S.v.Sidorov.A.S.Kornilov. t.Yu.t.et.akov. Facult. of Physics Lomonosov Moscow State UniversityMoscow 119991Russia Skobelt.yn Inst.t.t. of Nuclear Physics Lomonosov Moscow State UniversityMoscow 119991Russia

t.e influence of t.e t.nsor int.ract.on of nucleons on t.e charact.rist.cs of neut.on-rich silicon and nickel isot.pes was st.died in t.is *** forces are considered wit.in t.e framework of t.e Hart.ee-Fock approach wit. t.e Skyrme *** addit.on of a t.nsor component.of int.ract.on is shown t. improv. t.e descript.on of t.e split.ings bet.een different.single-part.cle st.t.s and decrease nucleon-nucleon pairing correlat.ons in silicon and nickel *** at.ent.on was direct.d t.ward t.e role of isov.ct.r t.nsor forces relev.nt.t. t.e int.ract.on of like nucleons.

关键词： nuclear shell model t.nsor int.ract.on silicon isot.pes nickel isot.pes

How Common can t.e Origin of Clust.rs Cha Ⅰ, Cha Ⅱ, ∈Cha and η Cha be?

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Research in Ast.onomy and Ast.ophysics 2024年第5期24卷 28-34页

作者： v.v.Bobylev.A.t.Bajkov. Pulkov. Ast.onomical Observ.t.ry St.-Petersburg 196140Russia

t.e t.aject.ries of t.e groupings η Cha,∈Cha and Cha I,Cha II,const.uct.d backward in t.me,hav. been *** concluded t.at.t.e hypot.esis about.t.e joint.format.on of all four of t.ese clust.rs from one molecular cloud cannot.be complet.ly ***,10–15 Myr ago,all t.ese four clust.rs were locat.d at.approximat.ly t.e same height.abov. t.e plane of t.e ***,t.e gas-dust.clouds from which all t.ese four clust.rs were formed were locat.d on one broad *** is possible t.at.t.e appearance of t.e Cha I,Cha II,∈Cha and η Cha clust.rs may be associat.d wit. t.e impact.on such a front.of shock wav.s formed aft.r supernov. explosions in t.e Scorpius–Cent.urus *** est.mat.s of t.e kinemat.c ages of t.e clust.rs Cha I and Cha II are obt.ined as 0.12±0.19 and 0.05±0.15,*** is shown t.at.t.e minimum size of t.e Cha I-nort. and Cha I-sout. clust.rs corresponded t. t.e t.me of 0.55±0.24 Myr and 0.04±0.18 Myr ago,respect.v.ly,and approximat.ly1.5 Myr ago t.e dist.nce bet.een t.e t.aject.ries of t.ese t.o groupings was minimal.

关键词： st.rs dist.nces-st.rs kinemat.cs and dynamics-galaxies st.r format.on