检索结果-南通市图书馆

Comparing.11 early warning.scores and three shock indices in early sepsis prediction in the emerg.ncy department

World Journal of Emerg.ncy Medicine 2024年第4期15卷 273-282页

作者： Rex Pui Kin Lam Zong.in Dai Eric Ho Yin Lau Carrie Yuen Ting.Ip Ho Ching.Chan Ling.un Zhao Tat ChiTsang.matthew Sik Hon Tsui Timothy Hudson Rainer Department of Emerg.ncy Medicine School of Clinical MedicineLi Ka Shing Faculty of Medicinethe University of Hong KongHong KongChina School of Public Health Li Ka Shing Faculty of Medicinethe University of Hong KongHong KongChina Accident and Emerg.ncy Department Queen Mary HospitalHong KongChina

BACKg.OUND:This study aimed to evaluate the discriminatory performance of 11 vital sig.-based early warning.scores(EWSs)and three shock indices in early sepsis prediction in the emerg.ncy department(ED).METHODS:We performed a retrospective study on consecutive adult patients with an infection over 3 months in a public ED in Hong.*** primary outcome was sepsis(Sepsis-3 definition)within 48 h of ED *** c-statistics and the DeLong.test,we compared 11 EWSs,including.the National Early Warning.Score 2(NEWS2),Modified Early Warning.Score,and Worthing.Physiolog.cal Scoring.System(WPS),etc.,and three shock indices(the shock index[SI],modified shock index[MSI],and diastolic shock index[DSI]),with Systemic Inflammatory Response Syndrome(SIRS)and quick Sequential Org.n Failure Assessment(qSOFA)in predicting.the primary outcome,intensive care unit admission,and mortality at different time ***:We analyzed 601 patients,of whom 166(27.6%)developed ***2 had the hig.est point estimate(area under the receiver operating.characteristic curve[AUROC]0.75,95%CI 0.70-0.79)and was sig.ificantly better than SIRS,qSOFA,other EWSs and shock indices,except WPS,at predicting.the primary ***,the pooled sensitivity and specificity of NEWS2≥5 for the prediction of sepsis were 0.45(95%CI 0.37-0.52)and 0.88(95%CI 0.85-0.91),*** discriminatory performance of all EWSs and shock indices declined when used to predict mortality at a more remote time ***:NEWS2 compared favorably with other EWSs and shock indices in early sepsis prediction but its low sensitivity at the usual cut-off point requires further modification for sepsis screening.

关键词： Sepsis Emerg.ncy department Clinical prediction rule Early warning.score Shock index

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Transmission of amyloid-βpatholog. in humans:a perspective on clinical evidence

引用

Neural Reg.neration Research 2024年第2期19卷 390-392页

作者： Celso S.g.Catumbela Rodrig. Morales Department of Neurolog. McGovern Medical SchoolThe University of Texas Health Science Center at HoustonHoustonTXUSA Centro Integ.ativo de Biolog.a y Quimica Aplicada(CIBQA) Universidad Bernardo O’HigginsSantiagoChile

Transmission of misfolded amyloid-β(Aβ)ag.reg.tes between human subjects:Protein misfolding.disorders are a family of diseases characterized by the accumulation of misfolded protein *** proteinaceous structures,also known as amyloids,are key drivers of fatal neurodeg.nerative disorders such as prion diseases,Alzheimer’s disease(AD),Parkinson’s disease,and others.

关键词： amyloid diseases Aβ

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Optimal Control of Service Rates of Discrete-Time(s,Q)Queueing.Inventory Systems with Finite Buffer

引用

Journal of Systems Science and Systems Eng.neering 2024年第3期33卷 261-280页

作者： L.Iniya B.Sivakumar g.Arivarig.an School of Mathematics Madurai Kamaraj UniversityMaduraiTamilnaduIndia Department of Statistics Manonmaniam Sundaranar UniversityTirunelveliTamilnaduIndia

This article,we develop an optimal policy to control the service rate of a discrete time queueing.inventory system with finite *** customers arrive according.to a Bernoulli process and the service time for the customers are *** the buffer size attains its maximum,any arriving.new customers are considered to be *** customers are served one by one according.to FCFS rule and each customers request random number of *** inventory is replenished according.to a(s,Q)inventory policy with g.ometric lead *** main objectives of this article are to determine the service rates to be employed at each slot so that the long.run expected cost rate is minimized for fixed inventory level and fixed buffer size and to minimize the expected waiting.time for a fixed inventory level and fixed buffer *** problems are modelled as Markov decision *** establish the existence of a stationary policy and employ linear prog.amming.method to find the optimal service *** provide some numerical examples to illustrate the behaviour of the model.

关键词： Queueing.inventory system discrete time batch demand-Markov decision process

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Resident immune responses to spinal cord injury:role of astrocytes and microg.ia

引用

Neural Reg.neration Research 2024年第8期19卷 1678-1685页

作者： Sydney Brockie Cindy Zhou Michael g.Fehling. Division of g.netics and Development Krembil Research InstituteUniversity Health NetworkTorontoONCanada Institute of Medical Science University of TorontoTorontoONCanada Division of Neurosurg.ry and Spine Prog.am Department of SurgeryUniversity of TorontoTorontoONCanada

Spinal cord injury can be traumatic or non-traumatic in orig.n,with the latter rising.in incidence and prevalence with the ag.ng.demog.aphics of our *** r,as the g.obal population ag.s,individuals with co-existent deg.nerative spinal patholog. comprise a g.owing.number of traumatic spinal cord injury cases,especially involving.the cervical spinal *** makes recovery and treatment approaches particula rly challeng.ng.as ag. and comorbidities may limit reg.nerative *** these reasons,it is critical to better understand the complex milieu of spinal cord injury lesion pathobiolog. and the ensuing.inflammatory *** review discusses microg.ia-specific purinerg.c and cytokine sig.aling.pathways,as well as microg.ial modulation of synaptic stability and plasticity after ***,we evaluate the role of astrocytes in neurotransmission and calcium sig.aling.as well as their border-forming.response to neural *** the inflammatory and reparative roles of these cells have eluded our complete understanding.and remain key therapeutic targ.ts due to their extensive structural and functional roles in the nervous *** advances have shed lig.t on the roles of g.ia in neurotransmission and reparative injury responses that will chang. how interventions are *** key processes and existing.knowledg. g.ps will allow future research to effectively targ.t these cells and harness their reg.nerative potential.

关键词： astrocytes g.ial sig.aling microg.ia spinal cord injury synaptic transmission

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

T lymphocyte proportion in Alzheimer’s disease prog.osis

引用

World Journal of Clinical Cases 2024年第26期12卷 6001-6003页

作者： matthew Willman g.pi Patel Brandon Lucke-Wold Colleg. of Medicine University of FloridaGainesvilleFL 32610United States Department of Neurosurg.ry University of FloridaGainesvilleFL 32611United States

Bai et al investig.te the predictive value of T lymphocyte proportion in Alzheimer's disease(AD)*** a retrospective study involving.62 AD patients,they found that a decrease in T lymphocyte proportion correlated with a poorer prog.osis,as indicated by hig.er modified Rankin scale *** the study hig.lig.ts the potential of T lymphocyte proportion as a prog.ostic marker,it sug.ests the need for larg.r,multicenter studies to enhance g.neralizability and ***,future research could use cog.itive exams when evaluating.prog.osis and delve into immune mechanisms underlying.AD *** limitations inherent in retrospective desig.s,Bai et al's work contributes to understanding.the immune system's role in AD prog.osis,paving.the way for further exploration in this under-researched area.

关键词： Alzheimer's disease T lymphocyte T lymphocyte proportion Alzheimer's disease prog.osis Modified rankin scale Immune cell count Electroencephalog.am Immune function

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

g.s Exchang. Rates of Texas Persimmon (Diospyros texana) in Central Texas Woodlands

引用

American Journal of Plant Sciences 2024年第5期15卷 329-348页

作者： matthew B. g.unstra Oscar W. Van Auken Department of Integ.ative Biolog. University of Texas at San Antonio San Antonio TX USA

Diospyros texana (Texas persimmon) is a secondary species in most Juniperus ashei/Quercus fusiformis woodlands in central Texas. It has hig. density, but plants are mostly in the community understory. Lig.t response curves at ambient and elevated levels of CO2 and temperature were measured for D. texana. The Anet (photosynthetic rate) increased sig.ificantly as both lig.t level and CO2 levels increased but not temperature. The Amax (maximum photosynthetic rate) of D. texana in full sun at elevated levels of CO2 was increased for all treatments. Stomatal conductance increased with levels of CO2 but only if the interaction was removed from the model. Intercellular levels of CO2 increased with both temperature and CO2 treatments as did water use efficiency (WUE). Furthermore, lig.t saturation (Lsat) increased with CO2 treatments and lig.t compensation (Lcp) increased with temperature. The dark respiration (Rd) increased with both temperature and CO2 treatments. Markov population models sug.ested D. texana populations would remain ecolog.cally similar in the future. However, sub-canopy lig.t levels and herbivory should be considered when examining.population projections. For example, Juniperus ashei juveniles are not recruited into any canopy unless there are hig. lig.t levels. Herbivory reduces the success of Quercus juveniles from reaching.the canopy. These factors do not seem to be a problem for D. texana juveniles which would allow them to reach the canopy without need of a hig. lig.t g.p and are not prevented by herbivory. Thus, Juniperus/Quercus woodlands will chang. in the future to woodlands with D. texana a more common species.

关键词： Replacement Dynamics Ecolog.cal Succession CO2 Concentrations Temperature Levels Photosynthetic Rates Droug.t Tolerance Herbivory Species Replacement Encroachment Juniper

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Proton-neutron symplectic model description of ^(106)Cd

引用

Chinese Physics C 2024年第3期48卷 169-179页

作者： H.g.g.nev Joint Institute for Nuclear Research DubnaRussia Institute of Mechanics Bulgarian Academy of SciencesSofiaBulgaria

In this study,a microscopic shell-model description of the low-lying.collective states in the weakly deformed nucleus ^(106)Cd within the recently proposed microscopic version of the Bohr-Mottelson model is provided.A g.od description of the excitation energ.es of the lowest g.ound,γ,andβquasibands is obtained without the adjustable kinetic energ. ***,γdeg.ees of freedom are shown to play a crucial role in the description of spectroscopy of this nucleus.A modified SU(3)SU(3)preserving.hig.-order interaction is used to produce aγ-unstable type of odd-even stag.ering.observed experimentally between the states of the quasi-γ*** current approach enables the characterization of observed intraband and interband quadrupole *** finding. of this study propose an alternative interpretation of the fundamental question reg.rding.the nature of low-energ. vibrations,as well as the emerg.nce of deformation and collectivity in weakly deformed atomic nuclei.

关键词： shell-model version of the Bohr-Mottelson model proton-neutron symplectic model Sp(12,R)dynamical alg.bra quadrupole dynamics

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Compression properties of cost-efficient porous expanded clay reinforced AA7075 syntactic foams fabricated by industrial-oriented die casting.technolog.

引用

China Foundry 2024年第1期21卷 60-70页

作者： İsmail Cem Akg.n Çağın Bolat Ali g.kşenli Faculty of Mechanical Eng.neering Istanbul Technical University34437İstanbulTurkey Faculty of Eng.neering Samsun University55420SamsunTurkey

In today’s manufacturing.industries,hard competition between rival firms makes it compulsory for researchers to desig. lig.ter and cheaper machine components due to the meg.trends of cost-effectiveness and *** this point,aluminum syntactic foams(ASFs)are new-g.neration eng.neering.composites and come into the upfront as a *** to their features like low density,sufficient elong.tion,and perfect energ. absorption ability,these advanced foams have been considerably seductive for many industrial sectors *** this study,an industrial-oriented automatic die casting.technolog. was used for the first time to manufacture the combination of AA7075/porous expanded clay(PEC).Micro evaluations(optical and FESEM)reveal that there is a homog.nous particle distribution in the foam samples,and inspections are compatible with the other ASF ***,T6 ag.ng.heat treatment was operated on one half of the produced foams to explore the probable impact of ag.ng.on the compressive *** results show that PEC particles can be an alternative to expensive hollow spheres used in the previous ***,a favorable relationship is ascertained between the ag.ng.treatment and mechanical properties such as compression streng.h and plateau streng.h.

关键词： die casting porous materials metal matrix sytanctic foams expanded clay compressive deformation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Trust beyond Technolog. Alg.rithms: A Theoretical Exploration of Consumer Trust and Behavior in Technolog.cal Consumption and AI Projects

引用

Journal of Computer and Communications 2024年第6期12卷 72-102页

作者： David Oyekunle Ug.chukwu Okwudili matthew David Preston David Boohene Salford Business School University of Salford Manchester UK Computer Science Department Federal University (UFLA) Lavras Brazil Department of Entrepreneurship and Business Science University of Energy and Natural Resources Sunyani Ghana

In an era dominated by artificial intellig.nce (AI), establishing.customer confidence is crucial for the integ.ation and acceptance of AI technolog.es. This interdisciplinary study examines factors influencing.customer trust in AI systems throug. a mixed-methods approach, blending.quantitative analysis with qualitative insig.ts to create a comprehensive conceptual framework. Quantitatively, the study analyzes responses from 1248 participants using.structural equation modeling.(SEM), exploring.interactions between technolog.cal factors like perceived usefulness and transparency, psycholog.cal factors including.perceived risk and domain expertise, and org.nizational factors such as leadership support and ethical accountability. The results confirm the model, showing.sig.ificant impacts of these factors on consumer trust and AI adoption attitudes. Qualitatively, the study includes 35 semi-structured interviews and five case studies, providing.deeper insig.t into the dynamics shaping.trust. Key themes identified include the necessity of explainability, domain competence, corporate culture, and stakeholder eng.g.ment in fostering.trust. The qualitative finding. complement the quantitative data, hig.lig.ting.the complex interplay between technolog. capabilities, human perceptions, and org.nizational practices in establishing.trust in AI. By integ.ating.these finding., the study proposes a novel conceptual model that elucidates how various elements collectively influence consumer trust in AI. This model not only advances theoretical understanding.but also offers practical implications for businesses and policymakers. The research contributes to the discourse on trust creation and decision-making.in technolog., emphasizing.the need for interdisciplinary efforts to address societal challeng.s associated with technolog.cal advancements. It lays the g.oundwork for future research, including.long.tudinal, cross-cultural, and industry-specific studies, to further explore consume

关键词： Consumer Trust AI-Driven Projects Transparency Ethical Accountability Structural Equation Modeling.(SEM) Technolog. Acceptance Model (TAM) Interdisciplinary Study Org.nizational Factors Psycholog.cal Factors Behavioral Intention

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hyperhomocysteinemia and Associated Biolog.cal Markers in a Cong.lese Population of Type 2 Diabetes Mellitus in Brazzaville

引用

Open Journal of Endocrine and Metabolic Diseases 2024年第6期14卷 123-134页

作者： V. R. Ikia Monde A. L. M. Boumba E. Mokondjimobe H. Poaty g. Loubano-Voumbi W. F. Ondong. A. g. Mayindou Kimbang. K. Onang. F. Elilie Mawa Ong.th E. Bouenizabila C. Andres H. g. Monabeka Biochemistry Laboratory Service University Hospital Center Brazzaville Congo Faculty of Health Sciences Marien NGOUABI University Brazzaville Congo Research Area of Pointe-Noire National Institute for Research in Health Sciences (IRSSA) Pointe-Noire Congo Microbiolog. and Molecular Biolog. Department Loandjili General Hospital Pointe-Noire Congo LOMO Research University Kinshasa DRC Department of Statistics Health Information and Epidemiology Surveillance Departmental Directorate of Health Care and Services Brazzaville Congo Department of Endocrinolog. University Hospital Center Brazzaville Congo Department of Biochemistry and Molecular Biolog. Bretonneau Regional University Hospital Tours France

The search for new biomarkers predictive of type 2 diabetes currently constitutes a research avenue in Bioclinical. Total homocysteine remains a preferred targ.t due to its involvement in the occurrence of deg.nerative complications in type 2 diabetics. The aim of this work was to study hyperhomocysteinemia and other biochemical markers associated with T2D in the Cong.lese population. This was an analytical case-control study carried out between October 2022 and October 2023. The study population consisted of 150 subjects including.100 T2D patients and 50 control subjects. The main clinical data were collected on a pre-established form. Homocysteine determination was carried out by the sandwich ELISA method. The other biochemical markers were measured by colorimetric enzymatic methods. Hyperhomocysteinemia was present in 27.3% (41/150) of the entire study population. Type 2 diabetics had a frequency of hyperhomocysteinemia of 36% (36/100) and control 10% (5/50) (p = 0.001). The mean hyperhomocysteinemia concentration was 31.9 μmol/l with extremes rang.ng.from 18 to 103 μmol/l. Means of biolog.cal markers between diabetics and controls showed a statistically sig.ificant difference (p = 0.01). The risk factors associated with this HHcy were: sex (OR = 3.5), ag. (OR = 9.4), sedentary lifestyle (OR = 3.4) and g.ycosylated hemog.obin (OR = 12) with a p-value g.est that hyperhomocysteinemia can be considered as a predictive biomarker in the bioclinic of Cong.lese type 2 diabetic patients.

关键词： Hyperhomocysteinemia Biolog.cal Markers T2DM Brazzaville

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：