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Efficacy of radiofrequency ablation of hepatocellular carcinoma prior to liver transplantation and the need for competing-risk analysis

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Hepatobiliary Surgery and Nutrition 2018年第4期7卷 294-296页

作者： Alessandro Cucchetti matteo Serenari Department of Medical and Surgical Sciences - DIMEC Alma Mater Studiorum University of Bologna Bologna Italy

Radiofrequency ablation(RFA)currently represents a potentially curative treatment for hepatocellular carcinoma(HCC)in its early stages(1,2).Providing higher rates of complete necrosis of target tumor than other loco-regional therapies(LRTs),RFA plays an important role as bridge therapy to liver transplantation(LT)(3).In the study from Lee and colleagues of the UCLA medical center,published in issue of June 2017 of Hepatology,Authors analyzed the outcome of 121 patients with 156 de-novo HCC treated with RFA as initial stand-alone therapy(4).The study is a fair attempt to analyze the efficacy of RFA as bridge therapy to LT,considering all potential outcome ***,some results passed unnoticed,while instead deserve further discussion.

关键词： hepatocellular curative instead

PSMA PET/CT in the low-to intermediate-risk prostate cancer:when and why?

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Asian Journal of Andrology 2024年第6期26卷 584-586页

作者： Luca Sofia matteo Bauckneht Department of Health Sciences(DISSAL) University of GenovaGenova 16132Italy Nuclear Medicine IRCCS Ospedale Policlinico San MartinoGenova 16132Italy

Prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) represents a significant advancement in the imaging of prostate cancer (PCa), yet its application in low- and intermediate-risk cases continues to be a topic of active discussion. This article delves into the nuanced role of PSMA PET/CT, critically analyzing its strengths and limitations in these specific risk categories. For patients with low-risk PCa, PSMA PET/CT demonstrates limited effectiveness in routine staging due to its minimal tracer uptake in low-grade tumors. However, its ability to differentiate between low- and high-grade tumors suggests a promising role in active surveillance, offering a potential noninvasive method for monitoring disease progression and aiding in treatment decision-making. In the intermediate-risk PCa setting, the high specificity of PSMA PET/CT in nodal staging makes it a valuable asset for precise surgical and radiation therapy planning. The article underscores the necessity for further research to fully realize the potential of PSMA PET/CT in PCa management, particularly in developing more personalized treatment approaches in these clinical scenarios.

关键词： routine intermediate treatment

A WKNN-based approach for NB-IoT sensors localization

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Digital Communications and Networks 2023年第1期9卷 175-182页

作者： Ennio Gambi Linda Senigagliesi Andrea Barbaresi matteo Mellini Adelmo De Santis Department of Information Engineering Universita Politecnica delle Marche60131AnconaItaly TIM S.p.A.-Business-Pre Sales Engineer 60100AnconaItaly

With the recent introduction of NarrowBand Internet of Things(NB-IoT)technology in the 4th and 5th generations of mobile radio networks,the mobile communications context opens up significantly to the world of *** means of NB-IoT,the mobile systems within 3GPP standardization introduce the peculiar functions of sensor networks,thus making it possible to satisfy very specific requirements with respect to those which characterize traditional mobile *** the functions of interest for sensor networks,the possibility of locating the positions of the sensors without an increase in costs and energy consumption of the sensor nodes is of utmost *** present work describes a procedure for locating the NB-IoT nodes based on the quality of radio signals received by the mobile terminals,which therefore does not require further hardware implementations on board the *** procedure,based on the RF fingerprinting technique and on machine learning processing,has been tested experimentally and has achieved interesting performances.

关键词： Narrowband Internet of Things(NB-IoT) Sensor localization Sensor networks RF fingerprint Positioning LTE

Experimental Validation of Light Cable-Driven Elbow-Assisting Device L-CADEL Design

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Journal of Bionic Engineering 2022年第2期19卷 416-428页

作者： Med Amine Laribi Marco Ceccarelli Juan Sandoval matteo Bottin Giulio Rosati Department GMSC Pprime InstituteCNRS-University of Poitiers-ENSMAUPR 334686073 PoitiersFrance Department of Industrial Engineering University of Rome Tor Vergata00133 RomeItaly Department of Industrial Engineering University of Padova35122 PaduaItaly

This paper presents a new design of CADEL,a cable-driven elbow-assisting device,with light weighting and control *** new device design is appropriate to be more portable and user-oriented solution,presenting additional facilities with respect to the original *** of potential benefits of improved portability can be envisaged in the possibility of house and hospital usage keeping social distancing while allowing rehabilitation treatments even during a pandemic *** attention has been devoted to design main mechatronic components by developing specific kinematics *** design process includes an implementation of specific control hardware and *** kinematic model of the new design is formulated and features are evaluated through numerical simulations and experimental *** evaluation from original design highlights the proposed improvements mainly in terms of comfort,portability and user-oriented operation.

关键词： Rehabilitation robotics Medical devices Design Simulations Cable-driven parallel robot Control

Orthostatic hypertension and adverse clinical outcomes in adults and older people

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Journal of Geriatric Cardiology 2021年第9期18卷 779-782页

作者： Sarah Damanti Paolo D Rossi matteo Cesari Unit of General Medicine and Advanced Care IRCCS San Raffaele InstituteMilanItaly Geriatric Unit Fondazione IRCCS Ca’Granda Ospedale Maggiore PoliclinicoMilanoItaly Department of Clinical Sciences and Community Health University of MilanMilanItaly Geriatric Unit IRCCS Istituti Clinici Scientifici MaugeriMilanItaly

Orthostatic hypertension(OHT)is a condition characterized by an increase in blood pressure after assuming the standing position.[1]Nowadays no consensus definition exists,thus OHT prevalence varies among studies(4%-20... 详细信息

关键词： hypertension clinical prevalence

Measurement of strong phases,D- mixing,and CP violation using quantum correlation at charm threshold

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Frontiers of Physics 2016年第1期 5-19页

作者： matteo Rama Sezione di Pisa dell'Istituto Nazionale di Fisica Nucleare

We review the measurements of the D decay strong-phase parameters based on quantum-correlated D00pairs produced in the e+e-→ψ（3770）→ D00process,and we discuss their role in the measurements of Cabibbo-Kobayashi-Maskawa angle γ and D- *** addition,we present estimates of the size of quantum-correlated datasets necessary to support the 7 and charm mixing measurements conducted at the LHCb and Belle Ⅱ ***,we review the methods for measuring the D- mixing and CP violation parameters at a high-luminosity charm factory,giving sensitivity estimates.

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Spatio-temporal visualization of light transport in complex photonic structures

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Light(Science & Applications) 2016年第1期5卷 714-722页

作者： Lorenzo Pattelli Romolo Savo matteo Burresi Diederik S Wiersma European Laboratory for Non-linear Spectroscopy(LENS) Universitàdi FirenzeSesto Fiorentino(FI)50019Italy Istituto Nazionale di Ottica(CNR-INO) Firenze(FI)50125Italy Dipartimento di Fisica e Astronomia Universitàdi FirenzeSesto Fiorentino(FI)50019Italy Laboratoire Kastler Brossel UMR 8552CNRSEcole Normale SupérieureUniversitéPierre et Marie CurieCollège de France24 rue LhomondParis 75005France Gestione SILO Srl via di Castelpulci 14/dScandicci(FI)50010Italy

Spatio-temporal imaging of light propagation is very important in photonics because it provides the most direct tool available to study the interaction between light and its host ***-ps time resolution is needed to investigate the fine and complex structural features that characterize disordered and heterogeneous structures,which are responsible for a rich array of transport physics that have not yet been fully explored.A newly developed wide-field imaging system enables us to present a spatiotemporal study on light transport in various disordered media,revealing properties that could not be properly assessed using standard *** extending our investigation to an almost transparent membrane,a configuration that has been difficult to characterize until now,we unveil the peculiar physics exhibited by such thin scattering systems with transport features that go beyond mainstream diffusion modeling,despite the occurrence of multiple scattering.

关键词： diffusive approximation disordered media light transport optical gating wide-field imaging

Wolf predation on wild ungulates:how slope and habitat cover influence the localization of kill sites

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Current Zoology 2018年第3期64卷 271-275页

作者： Elisa TORRETTA Luca CAVIGLIA matteo SERAFINI Alberto MERIGGI Di.S.T.A. Universita degli Studi di PaviaVia Ferrata 1Pavia 27100Italy

Based on data collected along the Ligurian Apennines and Alps(N-W Italy),we analysed the main environmental and human-related factors influencing the distribution of kill sites of the wolf Canis *** mapped and digitized 62 kill sites collected during *** each kill site,we defined a buffer corresponding to the potential hunting area of *** compared kill site plots and an equal number of random *** formulated a model of kill site distribution following an approach presence versus availability by binary logistic regression analysis;we tested the hypothesis that wolf choice of kill sites is influenced by the physiography and the land use of the *** the preyed wild ungulates,we identified 23 roe deer Capreolus capreolus,18 fallow deer Dama dama,16 wild boars Sus scrofa,and 5 chamois Rupicapra *** logistic regression analysis showed a negative effect of the road density,the urban areas,the mixed forests,and a positive effect of steep slopes and open *** are more vulnerable to predators under certain conditions and predators are capable of selecting for these *** achieved this by selecting particular habitats in which to kill their prey:they preferred steep,open habitats far from human presence,where wild ungulates are more easily detectable and chasable.

关键词： Canis lupus hunting habits kill site distribution modeling predator-prey interaction wild ungulates.

Predictive calculations of gas solubility and permeability in glassy polymeric membranes： An overview

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Frontiers of Chemical Science and Engineering 2017年第3期11卷 405-413页

作者： matteo Minelli Maria G. De Angelis Giulio C. Sarti Department of Civil Chemical Environmental and Materials Engineering Alma Mater Studiorum-University of Bologna Bologna 28-40131 Italy

The possibility to evaluate in a predictive way the relevant transport properties of low molecular weight species, both gases and vapors, in glassy polymeric membranes is inspected in detail, with particular attention to the methods recently developed based on solid thermodynamic basis. The solubility of pure and mixed gases, diffusivity and permeability of single gases in polymer glasses are examined, considering in particular poly（2,6-dimethyl-1,4-phenylene oxide） as a relevant test case. The procedure clearly indicates what are the relevant physical properties of the polymer matrix and of the penetrants required by the calculations, which can be obtained experimentally through independent measurements. For gas and vapor solubility, the comparison with direct experimental data for mixed gases points out also the ability to account for the significant variations that solubility-selectivity experiences upon variations of pres- sure and/or feed composition. For gas and vapor perme- ability, the comparison with direct experimental data shows the possibility to account for the various different trends observed experimentally as penetrant pressure is increased, including the so-called plasticization behavior. The procedure followed for permeability calculations leads also to clear correlations between permeability and physical properties of both polymer and penetrant, based on which pure predictive calculations are reliably made.

关键词： solubility permeability glassy polymers NELF model diffusion