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Comprehensive and innovative techniques for livertransplantation in rats: A surgical guide

World Journal of Gastroenterology 2010年第25期16卷 3120-3132页

作者： Tomohide hori Justin h Nguyen Yasuhiro Ogura Toshiyuki hata Shintaro Yagi Ann-Marie T Baine Norifumi Ohashi Christopher B Eckman Aimee R herdt hiroto Egawa Yasutsugu Takada Fumitaka Oike Seisuke Saka-moto Mureo Kasahara Kohei Ogawa Koichiro hata Taku Iida Yukihide Yonekawa Lena Sibulesky Kagemasa Kuribayashi Takuma Kato Kanako Saito Mie Torii Naruhiko Sahara Naoko Kamo Tomoko Sahara motohiko Yasutomi Shinji Uemoto Department of Neuroscience Mayo Clinic Jacksonville Florida FL 32224 United States Division of hepato-Pancreato-Biliary Transplant and Pediatric Surgery Department of Surgery Kyoto University HospitalSakyo-ku Kyoto 606-8507 Japan Division of Transplant Surgery Department of Transplantation Mayo Clinic Jackson-ville Florida FL 32224 United States Institute for Laboratory Animal Science and Ex-perimental Surgery RWTH-Aachen University D-52074 AachenGermany Department of Cellular and Molecular Immu-nology Mie University Graduate School of Medicine Tsu Mie514-8507 Japan New Zealand Liver Transplant Unit Auckland City Hospital Auckland 92024 New Zealand

AIM: To investigate our learning curves of orthotopic liver transplantation (OLT) in rats and the most important factor for successful surgery. METhODS: We describe the surgical procedures for our rat OLT model, and determined the operator learning curves. The various factors that contributed to successful surgery were determined. The most important surgical factors were evaluated between successful and unsuccessful ***: Learning curve data indicated that 50 cases were required for operator training to start a study. Operative time, blood loss, warm ischemic time, anhepatic phase, unstable systemic hemodynamic state, and body temperature after surgery significantly affected surgery success by univariate analysis, while the anhepatic phase was the most critical factor for success by multivariate analysis. CONCLUSION: OLT in rats is the only liver transplantation model that provides clinically relevant and reliable results. Shortened anhepatic phase is key to success in this model.

关键词： Animal model Liver transplantation Microsurgery Rat Reperfusion injury Ultra-microsurgery

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motorola亟思以转型力挽狂澜

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电子测试 2003年第12期16卷 49-53页

作者： K.h

在过去75年间,motorola一直站在无线技术产业领导的地位,而原本只是一个汽车无线技术制造商的motorola,到后来进入移动电话系统的设计,其事业的扩充与转型使得motorola已经扩编至6个主要的事业部:个人通讯部门(Personal Communica-tions... 详细信息

在过去75年间,motorola一直站在无线技术产业领导的地位,而原本只是一个汽车无线技术制造商的motorola,到后来进入移动电话系统的设计,其事业的扩充与转型使得motorola已经扩编至6个主要的事业部:个人通讯部门(Personal Communica-tions Sector)、全球电信解决方案部门(Global Telecom Solutions Sector)、商业、政府与产业解决方案部门(Commercial,Government and Industrial SolutionsSector)、宽带通讯部门(Broadband Com-munications Sector)、半导体产品部门(Semiconductor Product Sector)与集成电子系统部门(Integrated Electronics SystemSector)等。不过,随着motorola在半导体以及移动电话的市场占有率逐年下滑,motorola正面临一个前所未有的挑战,包含半导体产品部门是否要切割出去的议题等。motorola到底该如何转型以跳脱现在的困境,本文将评论未来转型是否真能使"moto"获得重生呢?

关键词： motorol公司移动电话操作系统 SmartPhone Symbian LinuxOS

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早产儿足月时的脑结构异常

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世界核心医学期刊文摘（儿科学分册） 2006年第8期2卷 60-61页

作者： Inder T. E. Warfield S. K. Wang h. 俞晓梅(译) - PEDIATRICS 2005 115/2 (286-294) 不详

***-term studies of the outcome of very prematurely born infants have clearly documented that the majority of such infants have significant moto r,cognitive,and behavioral ***,there is a limited understanding of the nature of the cerebral abnormality underlying these adverse neurologic o *** overall aim of this study was to define quantitatively the alt erations in cerebral tissue volumes at term equivalent in a large longitudinal c ohort study of very low birth weight premature infants in comparison to term-bo rn infants by using advanced volumetric 3-dimensional magnetic resonance imagin g(MRI)*** also aimed to define any relationship of such perinatal l esions as white matter(WM)-injury or other potentially adverse factors to the quantitative structural ***,we wished to identify the rel ationship of the structural alterations to short-term neurodevelopmental outcom *** November 1998 to December 2000,119 consecutive premature infan ts admitted to the neonatal intensive care units at Christchurch Women’s hospit al(Christchurch,New Zealand)and the Royal Women’s hospital(Melbourne,Austr alia)were recruited(88%of eligible)after informed parental consent to underg o an MRI scan at term ***-one term-born infants across both sit es were recruited *** advanced 3-dimensional tissue segmentat ion with 3-dimensional reconstruction was undertaken to estimate volumes of cer ebral tissues:gray matter(GM;cortical and deep nuclear structures),WM(myelinated and unmyelinated),and cerebrospinal fluid(CSF).*** comp arison to the term-born infants,the premature infants at term demonstrated pro minent reductions in cerebral cortical GM volume(premature infants [mean ±SD]:178 ±41 mL;term infants:227 ±26 mL)and in deep nuclear GM volume(prematur e infants:10.8 ±4.1 mL;term infants:13.8 ±5.2 mL)and an increase in CSF vo lume(premature infants:45.6 ±22.1 mL;term infants:28.9

关键词：极低出生体重早产儿脑结构异常足月新生儿重症监护病房三维重建不良转归结构改变妇产医院磁共振成像 MRI扫描

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低温振荡处理对香菇子实体的萌发,类脂化合物的构型和营养成分转移的影响

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生物技术 1992年第3期2卷 46-46,40页

作者： C.h.Song K.Y.Cho N.G.Nair 王慧颖宋真江青彦

食用菌子实体的萌发常被许多环境因素所控制,诸如光、相对湿度、通风和温度等.就香菇而言,已报导了长满菌丝的培养料经进一步浸没在冷水中处理能够增加子实体的产量(Manashere,1977;matsu-moto和Kitamoto,1987),并观察了它可能影响几丁... 详细信息

食用菌子实体的萌发常被许多环境因素所控制,诸如光、相对湿度、通风和温度等.就香菇而言,已报导了长满菌丝的培养料经进一步浸没在冷水中处理能够增加子实体的产量(Manashere,1977;matsu-moto和Kitamoto,1987),并观察了它可能影响几丁质酶活力(Tok(?)mo(?),1988),但没有详细研究低温对子实体萌发的影响的生理学基础.本文报告了低温振荡处理生长在固体培养料和合成琼脂培养基中(体外)菌体对子实体的萌发以及振荡培养香菇对菌丝类脂化合物的构型和营养成分转移的影响.长满香菇菌丝的半固体培养基和固体培养基分别在5℃冷水中浸没24hr。

关键词：香菇子实体低温振荡

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手术治疗癫痫的适应证和并发症

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世界核心医学期刊文摘（神经病学分册） 2005年第2期1卷 58-59页

作者： Gu'enot Serv. Neurochirurg. Stereotax. F. enot M. M. Gu'h.opital P. Wertheimer 张玉龙 59 Bd Pinel 69003 Lyon France

To be considered for resective (curative) surgery, most seizures have to been proved to arise exclusively from one area of the brain that is functionally sile nt. The drug resistance must be certain, and the patient must be strongly motiv ated to undergo surgery. Temporal lobectomy for drug resistant temporo me sia l epilepsy is now scientifically validated by a randomized controled trial. hemi spherotomy, which consists in complete disconnection of one hemisphere, is a cur ative technique, which may be considered where there is a pre existing hemipleg iaassociated with a structural abnormality of the contralateral hemisphere. Ther efore, it is rarely performed in adult patients. Stereotactic radiosurgery is al so a curative technique, which shares most of its indications with those of temp oro mesial re sections. Callosotomy is a palliative technique, which consists in disconnecting the hemispheres, one from the other. It may be considered in in dividuals having frequent atonic seizures (drop attacks). Multiple subpial trans ection involves transection of transverse fibers, leaving longitudinal fibers in tact. It may be performed if the epileptogenic focus is located in an eloquent b rain area. The complication rate of resective surgery is low. Controlateral moto r impairement is the main permanent complication related to cortical resection. It is a rare occurence (1 to 2 percent of cases) due to peroperative lesions of the sylvian vasculature, or of the anterior choroidal artery, or even of the mot or area. Postoperative hematomas, infections, or hydrocephalus may also occur in 2 to 6 percent of cases, depending on the authors. Some postoperative neuropsyc hological complications are reported in the literature, especially after surgery on the dominant side. hydrocephalus and infection are the most frequent complic ations occuring after hemispherotomy (10 percent of cases). Dysconnexion syndrom is a rare complication, which can be seen after total callosotomy. It i

关键词：半球切除术大脑半球胼胝体切开软膜术后神经功能癫痫病灶频发性优势半球随机对照试验脉络膜前动脉

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