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Topical nitrate drip infusion using cystic duct tube for retained bile duct stone:A six patients case series

World Journal of Gastrointestinal Surgery 2013年第6期5卷 210-215页

作者： Masatoshi Shoji Hiroshi Sakuma Yutaka Yoshimitsu Tsutomu Maeda masuo nakai Hiroshi Ueda Department of Surgery Hoju Memorial HospitalNomiIshikawa 923-1226Japan

A retained bile duct stone after operation for cholelithiasis still occurs and causes symptoms such as biliary colic and obstructive *** endoscopic retrograde cholangiopancreatography with endoscopic sphincterotomy(EST),followed by stone extraction,are usually an effective treatment for this ***,these procedures are associated with severe complications including pancreatitis,bleeding,and duodenal *** such as glyceryl trinitrate(GTN) and isosorbide dinitrate(ISDN) are known to relax the sphincter of *** 6 cases in which a retained stone was detected following cholecystectomy,topical nitrate drip infusion via cystic duct tube(C-tube) was carried *** stones of 2-3 mm diameter and no dilated common bile duct in 3 patients were removed by drip infusion of 50 mg GTN or 10 mg ISDN,which was the regular dose of intravenous *** other cases failed,and EST in 2 cases and endoscopic biliary balloon dilatation in 1 case were *** patient developed an adverse event of *** complications were not *** consider the topical nitrate drip infusion via C-tube to be old but safe,easy,and inexpensive procedure for retained bile duct stone following cholecystectomy,inasmuch as removal rate was about 50% in our cases.

关键词： Nitrate Topical drip infusion Cystic duct tube Retained bile duct stone Cholecystectomy

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