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Assessment of slow deformations and landslide modelling in the urban area through a multi-methodological approach

Journal of Earth Science 2024年

作者： Fabio Ietto massimo Conforti Cristiano Tolomei Federico Cella giuseppe Cianflone Università degli Studi della Calabria Dipartimento di Biologia Ecologia e Scienze della Terra (DiBEST) Via P.Bucci Cubo 15B 87036 Consiglio Nazionale Ricerche (CNR) Istituto di Ricerca per la Protezione Idrogeologica (IRPI) Via Cavour INGV-Istituto Nazionale di Geofisica e Vulcanologia Via di Vigna Murata 605 Università di Camerino Scuola di Scienze e Tecnologia Sez.Geologia Via Gentile III da Varano 27

Slow-moving landslides are widespread in the Mediterranean area， causing damage to the exposed facilities and economic losses in many countries. The recognition of slow-moving landslides in urban areas is always a difficult task to deal with because the presence of buildings， infrastructures， and human activities usually conceals the morphological signs of these landslide activities. So， in the last decades， numerous researchers have shown new methodologies to deepen the studies of similar instability phenomena. The present research is based on an integrated approach to investigate the landslide boundaries， type of movement， failure surface depth， and vulnerability state of buildings in Rota Greca village (Calabria region， southern Italy) affected by a slow-moving landslide. For this purpose， multi-source data were acquired through geological and geomorphological surveys， recognition of landslide-induced damage on the built environment， subsurface investigations (e.g.， continuous drill boreholes， Standard Penetration Test， Rock Quality Designation index and inclinometer monitoring)， laboratory tests (direct shear tests on undisturbed samples)， geophysical survey， and InSAR-derived map of deformation rates. The complete integration of multi-source data allowed for the construction of reliable landslide modelling with relative geotechnical properties. In addition， the cross-comparison between surface deformation data by SAR images and severity damage level collected on the exposed buildings enabled to obtain the vulnerability map of the built area. In particular， the achieved goals highlighted two failure surfaces at about -13 and -25 m depth， causing a high vulnerability value for the buildings allocated in the central portion of the Rota Greca village. The knowledge acquired by the multi-approach can be used to manage and implement appropriate landslide risk mitigation strategies， providing helpful advice and best practices to state-run organisations and stakeholder

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Consensus on management of hepatitis C virus infection in resource-limited Ukraine and Commonwealth of Independent States regions

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World Journal of Gastroenterology 2019年第29期25卷 3897-3919页

作者： massimo giuseppe colombo Erkin Isakovich Musabaev Umed Yusupovich Ismailov Igor A Zaytsev Alexander V Nersesov Igor Anatoliyevich Anastasiy Igor Alexandrovich Karpov Olga A Golubovska Kulpash S Kaliaskarova Ravishankar AC Sanjay Hadigal Research and Clinical Center Department of Medicine Humanitas Hospital Rozzano 20089 MI Italy Research Institute of Virology Scientific Research Institute of Virology Tashkent 100194 Uzbekistan Hepatoсenter Research Institute of Virology Scientific Research Institute of Virology Tashkent 100194 Uzbekistan Department of Therapy Infectious Diseases and Dermatology Bogomolets National Medical University Kyiv 01601 Ukraine Department of Gastroenterology and Hepatology National Research Institute of Cardiology and Internal Diseases Almaty 050000 Kazakhstan Department Infectious Diseases Bogomolets National Medical University Kyiv 01601 Ukraine Department Infectious Diseases Belarus State Medical University Minsk 220116 Belarus Hepatology Ministry of Health Astana 010000 Kazakhstan Medical Affairs Mylan Pharmaceuticals Private Limited Kadubeesanahalli Bengaluru 560103 India

Globally, 69.6 million individuals were infected with hepatitis C virus (HCV) infection in 2016. Of the six major HCV genotypes (GT), the most predominant one is GT1, worldwide. The prevalence of HCV in Central Asia, which includes most of the Commonwealth of Independent States (CIS), has been estimated to be 5.8% of the total global burden. The predominant genotype in the CIS and Ukraine regions has been reported to be GT1, followed by GT3. Inadequate HCV epidemiological data, multiple socio-economic barriers, and the lack of regionspecific guidelines have impeded the optimal management of HCV infection in this region. In this regard, a panel of regional experts in the field of hepatology convened to discuss and provide recommendations on the diagnosis, treatment, and pre-, on-, and posttreatment assessment of chronic HCV infection and to ensure the optimal use of cost-effective antiviral regimens in the region. A comprehensive evaluation of the literature along with expert recommendations for the management of GT1-GT6 HCV infection with the antiviral agents available in the region has been provided in this review. This consensus document will help guide clinical decision-making during the management of HCV infection, further optimizing treatment outcomes in these regions.

关键词： Antiviral agents Commonwealth of Independent States Genotype Hepatitis C virus Sustained virologic response Ukraine

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Feasibility of therapeutic endoscopic ultrasound in the bridge-to-surgery scenario:The example of pancreatic adenocarcinoma

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World Journal of Gastroenterology 2022年第10期28卷 976-984页

作者： giuseppe Vanella Domenico Tamburrino Gabriele Capurso Michiel Bronswijk Michele Reni giuseppe Dell'Anna Stefano Crippa Schalk Van der Merwe massimo Falconi Paolo Giorgio Arcidiacono Pancreatobiliary Endoscopy and EUS Division Pancreas Translational&Clinical Research CenterIRCCS San Raffaele Scientific InstituteVita-Salute San Raffaele UniversityMilan 20132Italy Pancreatic Surgery Unit Pancreas Translational&Clinical Research CenterIRCCS San Raffaele Scientific InstituteVita-Salute San Raffaele UniversityMilan 20132Italy Department of Gastroenterology and Hepatology University Hospital GasthuisbergUniversity of LeuvenLeuven 3000Belgium Department of Gastroenterology and Hepatology Imelda HospitalBonheiden 2820Belgium Department of Medical Oncology Pancreas Translational&Clinical Research CenterIRCCS San Raffaele Scientific InstituteMilan 20132Italy

Upfront resection is becoming a rarer indication for pancreatic ductal adenocarcinoma,as biologic behavior and natural history of the disease has boosted indications for neoadjuvant ***,gastric outlet obstruction and acute cholecystitis can frequently complicate this window of opportunity,resulting in potentially deleterious chemotherapy discontinuation,whose resumption relies on effective,prompt and long-lasting management of these *** therapeutic endoscopic ultrasound(t-EUS)can potentially offer some advantages over comparators,its use in potentially resectable patients is primal and has unfairly been restricted for fear of potential technical difficulties during subsequent *** is a narrative review of available evidence regarding EUS-guided choledochoduodenostomy,gastrojejunostomy and gallbladder drainage in the bridge-to-surgery ***-ofconcept evidence suggests no influence of t-EUS procedures on outcomes of eventual subsequent ***,the very high efficacy-invasiveness ratio over comparators in managing pancreatic cancer-related symptoms or complications can provide a powerful weapon against chemotherapy discontinuation,potentially resulting in higher subsequent *** evidence is discussed in this short paper,together with technical notes that might be useful for endoscopists and surgeons operating in this *** published evidence supports restricting t-EUS in potential surgical candidates,especially in the setting of pancreatic cancer patients undergoing neoadjuvant ***-to-surgery tEUS deserves further prospective evaluation.

关键词： Endosonography Gastrojejunostomy Choledochoduodenostomy Gallbladder drainage Pancreatic cancer Pancreatic surgery

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COVID-19 pandemic:An update on the reaction attitude of the spine societies and their members worldwide

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World Journal of Orthopedics 2022年第2期13卷 193-200页

作者： Alessandro Ramieri Omar Alshafeei Sokol Trungu Antonino Raco giuseppe Costanzo massimo Miscusi SAIMLAL Sapienza UniversityRome 00100Italy NESMOS Sapienza UniversityRome 00100Italy

BACKGROUND All surgical specialties have been influenced by the coronavirus disease 2019(COVID-19)pandemic,and substantial changes have been determined in medical assistance,especially in elective *** spine societies have published recommendations to provide optimal care during this unique *** To discuss the recommendations by many spine societies for the management of spinal diseases during the COVID-19 *** The present study was performed according to the PRISMA guidelines.A review of the MEDLINE database(PubMed–National Library of Medicine),Google,and Google Scholar was performed from March 2020 to date for articles published in the English *** Spine associations and societies worldwide were divided into three groups:Continental,specialty and country-based societies.A total of 27 spine associations were included in this *** were eight major continental associations,but only one-third of these had published guidelines and recommendations on this *** the other hand,the specialty-based societies have not addressed the topic,except in two *** The national spine societies showed the deepest concern on this topic with several publications in scientific journals influenced by the local epidemiological ***,continental and specialty-based societies showed less interest in this topic.

关键词： COVID-19 Pandemic Spine surgery Spine society Guidelines Recommendations

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Tree colonization by the Asian longhorn beetle, Anoplophora glabripennis （Coleoptera： Cerambycidae）： effect of habitat and tree suitability

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Insect Science 2016年第2期23卷 288-296页

作者： massimo Faccoli Riccardo Favaro giuseppe Concheri Andrea Squartini Andrea Battisti Department of Agronomy Food Natural resources Animals and Environment (DAFNAE) University of Padova Legnaro (PD) Italy

Tree colonization and feeding activity of the invasive wood-borer Asian longhorn beetle （Anoplophora glabripennis）, an Asian pest introduced into North America and Europe, was studied in a newly invaded area in Italy. The hypothesis be- ing tested was that the reproductive success of the insect depend on habitat type and tree suitability. Adult beetles were caged on branches of host and nonhost species, in both urban and forest habitats. Two months later, number and size of feeding patches on plant tissues, eggs laid, and surviving larvae were assessed. Bark concentration of C and N was also measured from the same trees. Results indicated that the mean area of plant tissues consumed by adult feeding was significantly larger on trees growing in forest than in urban habitat, although within the same habitat there were no differences between susceptible and nonsusceptible trees. ALB tree colonization, in terms of number of eggs laid and young larvae survival, was not affected by habitat while it was higher on susceptible trees. Although trees growing in forests had a lower nitrogen concentration, they allowed colo- nization rates similar to those of trees growing in the urban habitat. Hence, the amount of carbon and nitrogen did not fully explain tree suitability or habitat selection. We suggest compensatory feeding as a potential mechanism that might explain this peculiar situation, as supported by a more intensive feeding activity recorded on trees in the forest. Suitability of different trees may be due to other factors, such as secondary chemical compounds.

关键词： Asian longhorn beetle performance breeding feeding forest nonhost urban

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Comparison of Cardiorespiratory and Metabolic Responses Between Kettlebell Half Marathon and Treadmill Running at the Same Average Oxygen Consumption: A Case Study

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Journal of Science in Sport and Exercise 2021年第4期3卷 379-384页

作者： Davide Greco Luca Calanni giuseppe Cerullo massimo Negro giuseppe D’Antona CRIAMS-Sport Medicine Centre University of PaviaVogheraItaly Department of Movement Sciences and Wellbeing Parthenope UniversityNaplesItaly Department of Public Health Experimental and Forensic Medicine and Sport Medicine Centre VogheraUniversity of Paviavia Foscolo1327058 VogheraItaly

Purposes In kettlebell sport(KS)half marathon,the lift of the kettlebell is required for the highest number of repetitions in 30 *** data are available on cardiorespiratory and metabolic responses during this exercise *** aim of the study was to evaluate cardiopulmonary and metabolic responses to KS half marathon compared to 30 min treadmill running,chosen as a reference paradigm of aerobic exercise,at the same average oxygen consumption(VO_(2)).Methods A male elite KS athlete was enrolled in two trials separated by 7 days of *** the first trial,one-hand long-cycle KS exercise with a 1/3 body weight kettlebell was performed for 30 min(kettlebell half marathon,KT);in the second trial,30 min treadmill running(TR)was performed at the same average VO2 measured in the first trial(speed 9-10 km/h at 1°uphill inclination).Metabolic and cardiopulmonary assessments[respiratory exchange ratio(RER),tidal volume(TV),breathing frequency(f),minute ventilation(VE)],blood lactate(BL)kinetics,heart rate(HR),and blood pressure(BP)were measured in both experimental *** The average VO_(2) was 33.3 mL/min/kg in KT and 30.6 mL/min/kg in *** subject achieved RER_(peak) 1.17,RER_(mean) 0.98,HR_(peak) 172 bpm(94% HR_(max)),HR_(mean) 86% of HR_(max),BP_(peak) 220/100 mmHg in KT,BL_(peak) 7.2 mmol/L(during trial)in KT and RER_(peak) 1.13,RER_(mean) 0.89,HR_(peak) 142 bpm(78%HR_(max)),HR_(mean) 70% of HR_(max),BP_(peak) 160/80 mmHg,BL_(peak) 3.5 mmol/L(4 min after trial)mmol/L in *** Data indicate that a KS half marathon determines much higher cardiopulmonary and metabolic responses to treadmill running performed at similar VO_(2).

关键词： Kettlebell sport Blood lactate Blood pressure Heart rate Oxygen consumption

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Near-infrared spectroscopy in adult cardiac surgery： between conflicting results and unexpected uses

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Journal of Geriatric Cardiology 2017年第11期14卷 659-661页

作者： Antonio Nenna Raffaele Barbato Salvatore Matteo Greco giuseppe Pugliese Mario Lusini Elvio Covino massimo Chello Department of Cardiovascular Surgery Universita Campus Bio-Medico di Roma Rome Italy

Neurological complications after cardiac surgery, ranging from permanent stroke to transient dysfunction, represent a key issue in the management of geriatric patients. Many patients aged 70 or more have history of neurological dysfunctions, which increases the risk of complications and sequelae. Severe neurologic diseases, such as strokes, occur in up to 6% of patients undergoing cardiac surgery. Therefore, in the setting of fragile patients, prevention is more important than treatment. There are several intraoperative mechanisms of neurological injury, such as embolism, inflammation, intraoperative anemia, carotid or intracranial artery disease, but hypoperfusion appears to be the final common pathway of cerebral damage. Many systems to monitor cerebral oximetry and allow physicians to restore an adequate cerebral perfusion have been developed over the years. Among these, near-infrared spectroscopy (NIRS) has been extensively investigated and currently represents the non-invasive real-time tool to monitor the oxygen content of cerebral tissue during adult cardiac surgery. However, its effectiveness is highly debated, since current studies lead to controversial results. The existing literature raises four major questions:

关键词：外科心脏光谱学红外线成年机能障碍神经病并发症

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Hepatocellular carcinoma and synchronous liver metastases from colorectal cancer in cirrhosis:A case report

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World Journal of Hepatology 2013年第12期5卷 696-700页

作者： Marcello Maida Fabio Salvatore Macaluso massimo Galia giuseppe Cabibbo Section of Gastroenterology DIBIMISUniversity of Palermo Department of Radiology DIBIMEFUniversityPalermo

A 68-year-old Caucasian man with hepatitis C virus- related cirrhosis was admitted to our Unit in February 2010 for a diagnostic evaluation of three centimetric hypoechoic focal liver lesions detected by regular sur- veillance ultrasound. The subsequent computer tomog- raphy(CT) led to a diagnosis of unifocal hepatocellular carcinoma(HCC) in Ⅵ hepatic segment, defined the other two nodules in the Ⅵ and Ⅶ segment as sus- pected metastases, and showed a luminal narrowing with marked segmental circumferential thickening of the hepatic flexure of the colon. Colonoscopy detected an ulcerated, bleeding and stricturing lesion at the hepatic flexure, which was subsequently defined as ad- enocarcinoma with a moderate degree of differentiation at histological examination. Finally, ultrasound-guided liver biopsy of the three focal liver lesions confirmed the diagnosis of HCC for the nodule in the Ⅵ segment, and characterized the other two lesions as metastases from colorectal cancer. The patient underwent laparo- tomic right hemicolectomy with removal of thirty-nine regional lymph nodes(three of them tested positive for metastasis at histological examination), and simulta- neous laparotomic radio-frequency ablation of both nodule of HCC and metastases. The option of adju- vant chemotherapy was excluded because of the post- surgical onset of ascites. Abdomen CT and positron emission tomography/CT scans performed after 1, 6 and 12 mo highlighted a complete response to treat- ments without any radiotracer accumulation. After 18 mo, the patient died due to progressive liver failure. Our experience emphasizes the potential coexistence of two different neoplasms in a cirrhotic liver and the complexity in the proper diagnosis and management of the two tumours.

关键词： Hepatocellular carcinoma Colorectal can-cer Liver metastases Cirrhosis

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Petrogenesis of Quebrada de la Mina and Altar North porphyries (Cordillera of San Juan, Argentina): Crustal assimilation and metallogenic implications

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Geoscience Frontiers 2017年第5期8卷 1135-1159页

作者： Laura Maydagán Marta Franchini massimo Chiaradia Verónica Bouhier Noelia Di giuseppe Roger Rey Luis Dimieri Centro Patagónico de Estudios Metalogenéticos-CONICET Argentina INGEOSUR-CONICET Departamento de Geología Universidad Nacional del Sur San Juan 670 8000 Bahía Blanca Argentina Instituto de Investigación en Paleobiología y Geología Universidad Nacional de Río Negro Av. Roca 1242 8332 Roca Argentina Departamento de Geología y Petróleo Facultad de Ingeniería Universidad Nacional del Comahue Buenos Aires 1400 8300 Neuquén Argentina Section of Earth and Environmental Sciences University of Geneva Switzerland Minera Peregrine Argentina S.A Santa Fe (Oeste) 117 Piso 4B Edificio Derby Ciudad San Juan Argentina

We investigate the geology of Altar North(Cu-Au) and Quebrada de la Mina(Au) porphyry deposits located in San Juan Province(Argentina), close to the large Altar porphyry copper deposit(995 Mt,0.35% Cu, 0.083 g/t Au), to present constraints on the magmatic processes that occurred in the parental magma chambers of these magmatic-hydrothermal systems. Altar North deposit comprises a plagioclase-amphibole-phyric dacite intrusion(Altar North barren porphyry) and a plagioclaseamphibole-biotite-phyric dacite stock(Altar North mineralized porphyry, 11.98 ± 0.19 Ma). In Quebrada de la Mina, a plagioclase-amphibole-biotite-quartz-phyric dacite stock(QDM porphyry,11.91±0.33 Ma) crops out. High Sr/Y ratios(92-142) and amphibole compositions of Altar North barren and QDM porphyries reflect high magmatic oxidation states(fO_2= NNO+1.1 to+1.6) and high fH_2O conditions in their magmas. Zones and rims enriched in anorthite(An_(37-48))), SrO(0.22-0.33 wt.%)and FeO(0.21-0.37 wt.%) in plagioclase phenocrysts are evidences of magmatic recharge processes in the magma chambers. Altar North and Quebrada de la Mina intrusions have relatively homogeneous isotopic compositions(^(87)Sr/^(86)Sr_(t)= 0.70450-0.70466, ε_(ND)(t) = +0.2 to +1.2) consistent with mixed mantle and crust contributions in their magmas. Higher Pb isotopes ratios(^(207)Pb/^(204)Pb=15.6276-15.6294) of these intrusions compared to other porphyries of the district, reflect an increase in the assimilation of high radiogenic Pb components in the magmas. Ages of zircon xenocrysts(297,210,204,69 Ma) revealed that the magmas have experienced assimilation of Miocene, Cretaceous, Triassic and Carboniferous crustal *** that precipitated sulfides in the Altar deposit may have remobilized Pb from the host rocks, as indicated by the ore minerals being more radiogenic(207Pb/204 Pb = 15.6243-15.6269) than their host intrusions. Au/Cu ratio in Altar porphyries(average Au/Cu ratio of 0.14 ×10^(-4)by weight in Altar Central)is hig

关键词： Porphyry High sulfidation epithermal Magmatic recharge Radiogenic isotopes Crustal assimilation Argentinian Andes

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Correlations Between Myoelectric and Hemodynamic Parameters Changes in Biceps Brachii During Sustained Isometric Contraction in Healthy Elderly

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Journal of Science in Sport and Exercise 2019年第2期1卷 116-123页

作者： Cristian Zampella Luca Calanni Marco Barbero Corrado Cescon giuseppe Giovanetti massimo Negro giuseppe D’Antona CRIAMS-Sport Medicine Centre University of PaviaVogheraItaly Rehabilitation Research Laboratory 2rLab Department of Business EconomicsHealth and Social CareUniversity of Applied Sciences and Arts of Southern SwitzerlandMannoSwitzerland Department of Public Health Experimental and Forensic Medicine and Sport Medicine Centre VogheraUniversity of PaviaVia Foscolo1327058 VogheraPaviaItaly

Purpose The purpose of the present study was to evaluate the Pearson correlations between hemodynamic parameters obtained with near infrared spectroscopy (NIRS), namely total hemoglobin (tHb) and tissue oxygen index (TOI %), as indica-tors of blood flow and oxygen extraction, and myoelectric parameters obtained with surface multichannel electromyography (sEMG), namely fractal dimension (FD) and conduction velocity (CV) slopes, as descriptors of central and peripheral fatigue, during sustained high level isometric contractions at 60% maximal voluntary contraction (MVC), in elderly subjects. Methods Ten recreationally healthy elderly subjects (age 67.7 ± 4.6 years), 5 males and 5 females, performed one isometric contraction of the elbow flexors at 120° joint angle at 60% of MVC until exhaustion in two subsequent trials 1 week apart, one for the sEMG and the other one for NIRS recordings from the biceps brachii. Results A negative strong Pearson’s correlation between TOI % slope in the functional hyperemic phase (HP) of contrac-tion and a positive correlation between the slope of TOI % recorded during the ischemic phase (IP) and the CV slope were found (r = − 0.76, P < 0.05;r = 0.91, P < 0.01, respectively). A negative strong correlation between tHb IP slope and tHb HP slope and TOI % IP slope and TOI % HP slope (r = − 0.78, P < 0.01;r = − 0.78, P < 0.01, respectively) were also found. No correlation was found between FD slope and hemodynamic parameters (FD slope vs. HP tHb slope, r = − 0.19;FD slope vs. IP tHb slope, r = 0.16;FD slope vs. HP TOI % slope, r = 0.19;FD slope vs. IP TOI % slope, r = 0.27). Conclusion In aged individuals, CV slope correlated with muscle O2 desaturation (TOI %) rather than reduced muscle blood flow (tHb) in the ischemic phase of isometric contraction to exhaustion. No correlations were found between myoelectric manifestations of central fatigue (FD slope) and data obtained by NIRS.

关键词： Correlation between NIRS sEMG during muscle contraction

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