检索结果-南通市图书馆

Validation of user-friendly models predicting extracapsular extension in prostate cancer patients

Asian Journal of Urology 2023年第1期10卷 81-88页

作者： Leandro Blas Masaki Shiota Shohei Nagakawa Shigehiro Tsukahara Takashi Matsumoto Ken Lee Keisuke Monji Eiji Kashiwagi Junichi Inokuchi Masatoshi Eto Department of Urology Graduate School of Medical SciencesKyushu UniversityFukuokaJapan

Objective:There are many models to predict extracapsular extension(ECE)in patients with prostate cancer.We aimed to externally validate several models in a Japanese cohort.Methods:We included patients treated with robotic-assisted radical prostatectomy for prostate cancer.The risk of ECE was calculated for each patient in several models(prostate side-specific and non-side-specific).Model performance was assessed by calculating the receiver operating curve and the area under the curve(AUC),calibration plots,and decision curve analyses.Results:We identified ECE in 117(32.9%)of the 356 prostate lobes included.Patients with ECE had a statistically significant higher prostate-specific antigen level,percentage of positive digital rectal examination,percentage of hypoechoic nodes,percentage of magnetic resonance imaging nodes or ECE suggestion,percentage of biopsy positive cores,International Society of Urological Pathology grade group,and percentage of core involvement.Among the sidespecific models,the Soeterik,Patel,Sayyid,Martini,and Steuber models presented AUC of 0.81,0.78,0.77,0.75,and 0.73,respectively.Among the non-side-specific models,the memorial Sloan Kettering Cancer Center web calculator,the Roach formula,the Partin tables of 2016,2013,and 2007 presented AUC of 0.74,0.72,0.64,0.61,and 0.60,respectively.However,the 95%confidence interval for most of these models overlapped.The side-specific models presented adequate calibration.In the decision curve analyses,most models showed net benefit,but it overlapped among them.Conclusion:Models predicting ECE were externally validated in Japanese men.The side-specific models predicted better than the non-side-specific models.The Soeterik and Patel models were the most accurate performing models.

关键词： Prognosis Prostate cancer Nomogram Extracapsular extension

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Surgical Robot for Intraluminal Access:An Ex Vivo Feasibility Study

引用

Cyborg and Bionic Systems 2020年第1期2020卷 1-9页

作者： Ryu Nakadate Tsutomu Iwasa Shinya Onogi Jumpei Arata Susumu Oguri Yasuharu Okamoto Tomohiko Akahoshi Masatoshi Eto Makoto Hashizume Center for Advanced Medical Innovation Kyushu UniversityJapan Kitakyushu Municipal Medical Center Kyushu UniversityJapan Institute of Biomaterials and Bioengineering Tokyo Medical and Dental UniversityJapan Department of Mechanical Engineering Kyushu UniversityJapan Department of Advanced Medicine and Innovative Technology Kyushu University HospitalJapan Kyushu Central Hospital Japan Department of Urology Kyushu UniversityJapan Kyushu University Japan

Early-stage gastrointestinal cancer is often treated by endoscopic submucosal dissection(ESD)using a flexible endoscope.Compared with conventional percutaneous surgery,ESD is much less invasive and provides a high quality of life for the patient because it does not require a skin incision,and the organ is preserved.However,the operator must be highly skilled because ESD requires using a flexible endoscope with energy devices,which have limited degrees of freedom.To facilitate easier manipulation of these flexible devices,we developed a surgical robot comprising a flexible endoscope and two articulating instruments.The robotic system is based on a conventional flexible endoscope,and an extrapolated motor unit moves the endoscope in all its degrees of freedom.The instruments are thin enough to allow insertion of two instruments into the endoscope channel,and each instrument has a bending section that allows for up–down,right–left,and forward–backward motion.In this study,we performed an ex vivo feasibility evaluation using the proposed robotic system for ESD in a porcine stomach.The procedure was successfully performed by five novice operators without complications.Our findings demonstrated the feasibility of the proposed robotic system and,furthermore,suggest that even operators with limited experience can use this system to perform ESD.

关键词： Robot Access robot

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：