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Low-molecular-weight dextran for optical coherence tomography may not be protective against kidney injury in patients with renal insufficiency

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World Journal of Nephrology 2021年第2期10卷 8-20页

作者： Toru Misawa Tomoyo Sugiyama Yoshihisa Kanaji Masahiro Hoshino masao yamaguchi Masahiro Hada Tatsuhiro Nagamine Kai Nogami Yumi Yasui Eisuke Usui Tetsumin Lee Taishi Yonetsu Tetsuo Sasano Tsunekazu Kakuta Department of Cardiovascular Medicine Tsuchiura Kyodo General HospitalIbaraki 300-0028Japan Department of Interventional Cardiology Tokyo Medical and Dental UniversityTokyo 113-8519Japan Department of Cardiovascular Medicine Tokyo Medical and Dental UniversityTokyo 113-8519Japan

BACKGROUND Low-molecular-weight dextran(LMWD)is considered a safe alternative to contrast media for blood displacement during optical coherence tomography(OCT)*** To investigate whether the use of LMWD for OCT is protective against kidney injury in patients with advanced renal *** In this retrospective cohort study,we identified 421 patients with advanced renal insufficiency(estimated glomerular filtration rate<45 mL/min/1.73 m2)who underwent coronary angiography or percutaneous coronary intervention;79 patients who used additional LMWD for OCT imaging(LMWD group)and 342 patients who used contrast medium exclusively(control group).We evaluated the differences between these two groups and performed a propensity score-matched subgroup *** The median total volume of contrast medium was 133.0 mL in the control group vs 140.0 mL in the LMWD *** baseline renal function was not statistically different between these two groups,the LMWD group demonstrated a strong trend toward the progression of renal insufficiency as indicated by the greater change in serum creatinine level during the 1-year follow-up compared with the control *** in the LMWD group experienced worsening renal function more frequently than patients in the control *** score matching adjusted for total contrast media volume consistently indicated a trend toward worsening renal function in the LMWD group at the 1-year *** serum creatinine at 1-year follow-up was significantly greater in the LMWD group than that in the control group[0.06(-0.06,0.29)vs-0.04(-0.23,0.08)mg/dL,P=0.001],despite using similar contrast *** OCT using LMWD may not be protective against worsening renal function in patients with advanced renal insufficiency.

关键词： Coronary artery disease Kidney injury Contrast media Dextran Optical coherence tomography Renal insufficiency

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Effects of Asian dust events on atmospheric bacterial communities at different distances downwind of the source region

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Journal of Environmental Sciences 2018年第10期30卷 133-139页

作者： Jonguk Park Pin-Fang Li Tomoaki Ichijo masao Nasu Nobuyasu yamaguchi Graduate School of Pharmaceutical Sciences Osaka University1-6 Yamada-okaSuitaOsaka 565-0871Japan National Institutes of Biomedical Innovation Health and Nutrition7-6-8 Asagi Saito Ibaraki Osaka 567-0085 Japan College of Resources and Environmental Sciences China Agricultural University Beijing100193 China Faculty of Pharmacy Osaka Ohtani University3-11-1 Nishikiori-kita Tondabayashi Osaka 584-8540 Japan Osaka Institute of Public Health 1-3-69 Nakamichi Higashinari Osaka 537-0025 Japan

Aeolian dust particles arising from arid and semiarid zones are known to carry microbes by air currents. The effect of wind-borne bacteria on atmospheric bacterial population at various downwind distances from the dust source regions must be clarified, but has not yet been reported. This study monitored the bacterial abundance and community composition in outdoor aerosol samples in Beijing, China, which is close to the Asian dust source regions, and compared them with the results obtained in a distant region（Osaka, Japan）.The Asian dust collected in Beijing contained（4 ± 3） × 10^4 bacterial cells/m^3, approximately 4 times higher than in Osaka. On 15 April 2015, Beijing experienced severe Asian dust events with a 1000-fold increase in bacterial abundance, relative to non-Asian dust days. Dominant bacterial phyla and classes in Asian dust collected in Beijing were Actinobacteria, Bacilli and Acidobacteria, and the bacterial community composition varied more widely than in *** bacterial community compositions differed between the Beijing and Osaka dusts, even for the same Asian dust events. These results indicated that aerosol bacterial communities nearer the dust source are more affected by eolian dust than their distant counterparts.

关键词： Aeolian dust Amplicon sequencing Asian dust Bacterial community Bioaerosols

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A plant growth chamber system equipped with aerosol generators for studying aerosol-vegetation interactions

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Particuology 2024年第2期85卷 122-132页

作者： masao Gen Seiji Ikawa Masahiro yamaguchi Fong Zyin Lim Takeshi Izuta I.Wuled Lenggoro Graduate School of Bio-Applications and Systems Engineering Tokyo University of Agriculture and TechnologyKoganeiTokyo184-8588Japan Institute of Multidisciplinary Research for Advanced Materials Tohoku UniversitySendai980-8577Japan Faculty of Agriculture Tokyo University of Agriculture and TechnologyFuchuTokyo183-8509Japan Graduate School of Fisheries and Environmental Sciences Nagasaki UniversityNagasaki852-8521Japan Institute of Agriculture Tokyo University of Agriculture and TechnologyFuchuTokyo183-8509 Japan Department of Applied Physics and Chemical Engineering Tokyo University of Agriculture and TechnologyKoganeiTokyo184-8588Japan Institute of Global Innovation Research Tokyo University of Agriculture and TechnologyFuchuTokyo183-8509Japan

Understanding aerosol-vegetation interactions is vital in ***,the interactions remain elusive partly due to the lack of suitable plant growth chamber ***,deposition of submicron particles on leaf surfaces is challenging due to its low deposition velocities compared to larger *** this work,we present a plant-growth chamber that was used to study the effect of sub-micron black carbon(BC)particles on the growth and photosynthesis of *** chamber system simultaneously enables the growth of multiple plants in pots and the deposition of submicron particles onto *** spraying methods assisted by ultrasonic and electrostatic forces were employed as aerosol generators to realize the particle *** flow regime inside the chamber was numeri-cally calculated to predict the transportation of aerosol particles,suggesting the optimal operating conditions of the *** gas-phase particle size distribution measurements showed that gener-ated BC particles were suspended in submicron diameter *** aerosol generators were examined in the chamber using three conductor and insulator substrates as a model of plant *** observations and spectroscopic analysis ascertained that submicron BC particles generated from our generators were deposited on all substrate *** the developed chamber system,systematic studies can be performed to advance the fundamental understanding of aerosol-vegetation interactions.

关键词： Aerosol Exposure chamber Spray drying Black carbon

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Novel serum tumor marker, RCASl, in pancreatic diseases

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World Journal of Gastroenterology 2005年第33期11卷 5199-5202页

作者： Koji yamaguchi Munechika Enjoji Manabu Nakashima Makoto Nakamuta Takashi Watanabe masao Tanaka Department of Surgery and Oncology Graduate School of Medicine Kyushu University Japan Medicine Bioregulatory Sciences Graduate School of Medical Sciences Kyushu University Japan Department of Molecular Immunology Medical Institute of Bioregulation Faculty of MedicineKyushu UniversityJapan Department of Molecular Immunology Medical Institute of Bioregulation Faculty of Medicine Kyushu University Japan

AIM： As tumor markers for pancreatic carcinoma, carcinoembryonic antigen （CEA） and carbohydrate antigen （CA） 19-9 have been used, but the sensitivity and specificity are not enough for the diagnosis of pancreatic carcinoma. METHODS： A novel serum tumor marker, RCAS1, was compared with two conventional serum tumor markers, CEA （highly specific for pancreatic cancer） and CA 19-9 （highly sensitive for pancreatic cancer）, in 48 patients with pancreatic exocrine tumors. RESULTS： When the diagnosis of benign or malignant conditions was examined by one tumor marker, the sensitivity of RCAS1 alone （55%） was higher than that of CEA alone （27%） and the specificity of RCAS1 alone （92%） was greater than that of CA19-9 alone （78%）. When examined by a combination of two markers, the sensitivity of a combination of RCAS1 and CA19-9 （95%） was superior to those of CA19-9 alone （78%）, RCAS1 alone （55%, P = 0.002）, CEA alone （27%）（P〈0.001）, RCAS1 and CEA （59%） and CA19-9 and CEA （82%）. CONCLUSION： These results suggest that the combination of RCAS1 and CA19-9 is highly sensitive for pancreatic carcinoma.

关键词： RCASi CEA CA19-9 Pancreatic diseases

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Holography and speckle in phase-shifting digital holography(Invited Paper)

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Chinese Optics Letters 2009年第12期7卷 1104-1108页

作者： Ichirou yamaguchi Toyo Seiki Seisakusyo 1-2-6 Funado Itabashi-kuTokyo 174-0041 Japan

The correlation properties of the optical field diffusely reflected from a rough surface under coherent illumination are analyzed numerically. The cross-correlations of the complex amplitudes and the intensities before and after translation and/or tilt of the surface are calculated at an arbitrary observation plane in three-dimensional （3D） space. The results provide us with the 3D distributions of phase changes and speckle displacement that lead to the distributions measured by holographic interferometry and speckle relationships and physical interpretation of them are and signal-to-noise ratio of the displacement to be correlation technique. Comparisons with analytical also discussed.

关键词： CCD Holography and speckle in phase-shifting digital holography

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Clinical significance of serum levels of vascular endothelial growth factor and its receptor in biliary disease and carcinoma

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World Journal of Gastroenterology 2005年第8期11卷 1167-1171页

作者： Munechika Enjoji Makoto Nakamuta Koji yamaguchi Satoshi Ohta Kazuhiro Kotoh Marie Fukushima Masami Kuniyoshi Tomomi Yamada masao Tanaka Hajime Nawata Department of Medicine and Bioregulatory Science Department of Surgery and Oncology Medical Information Science

AIM: To investigate the clinical significance of serum vascular endothelial growth factor (VEGF) and soluble VEGF receptor-1 (VEGFRl/Flt-1) (sVEGFR1) levels in biliary diseases. METHODS: We analyzed the serum levels of these proteins in patients with acute cholangitis (group 1), biliary malignancies (group 2), and primary biliary cirrhosis or primary sclerosing cholangitis (group 3), and in healthy donors (group 4). The influence of inflammation was also analyzed. Serum VEGF levels were expressed as VEGF per platelet (VEGF/PLT, pg/106) in order to exclude the influence of platelet counts. RESULTS: sVEGFRl levels were significantly higher in groups 1 and 2 than in the control group, but did not correlate with inflammatory markers. VEGF/PLT levels were generally higher in patients with active inflammation than in those with carcinoma. C-reactive protein strongly correlated with the levels of serum VEGF independently of platelet and leukocyte counts, even in cancer patients. In cancer patients, VEGF/PLT and sVEGFRl levels might be indicators for evaluating the effect of medical treatment or the disease progression. CONCLUSION: Serum VEGF and VEGFR1 might be useful markers for gauging the clinical effect of various treatments on patients.

关键词： VEGF VEGFRl Cholangiocarcinoma Cholangitis

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Visible light responsive photocatalysts developed by substitution with metal cations aiming at artificial photosynthesis

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Frontiers in Energy 2021年第3期15卷 568-576页

作者： Yuichi yamaguchi Akihiko KUDO Department of Applied Chemistry Faculty of ScienceTokyo University of ScienceTokyo 162-8601Japan

To solve resource,energy,and environmental issues,development of sustainable clean energy system is strongly *** recent years,hydrogen has been paid much attention to as a clean *** hydrogen production by water splitting using a photocatalyst as artificial photosynthesis is a promising method to solve these *** utilization of visible light comprised of solar light is essential for practical *** strategies,i.e.,doping,control of valence band,and formation of solid solution are often utilized as the useful methods to develop visible light responsive *** minireview introduces the recent work on visible-light-driven photocatalysts developed by substitution with metal cations of those strategies.

关键词： visible light responsive photocatalyst water splitting artificial photosynthesis:metal ion substitution

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Nano-structural Modification of Amorphous Carbon Thin Films by Low-energy Electron Beam Irradiation

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材料热处理学报 2004年第05B期25卷 1247-1252页

作者： Eiji Iwamura Masanori yamaguchi PRESTO Japan Science and Technology Agency Tokyo JapanLamp Company Ushio INC. Himeji Japan

A new approach using a low-energy electron beam radiation system was investigated to synthesize carbon hybrid structures in amorphous carbon thin films. Two types of amorphous carbon films, which were 15at% iron containing film and with column/inter-column structures, were deposited onto Si substrates by a sputtering technique and subsequently exposed to an electron shower of which the energy and dose rate were much smaller compared to an intense electron beam used in a transmission electron microscopy. As a result of the low-energy and low-dose electron irradiation process, graphitic structures formed in amorphous matrix at a relatively low temperature up to 450 K. Hybrid carbon thin films containing onion-like structures in an amorphous carbon matrix were synthesized by dynamic structural modification of iron containing amorphous carbon thin films. It was found that the graphitization progressed more in the electron irradiation than in annealing at 773 K, and it was attributed to thermal and catalytic effects which are strongly related to grain growth of metal clusters. On the other hand, a reversal of TEM image contrast was observed in a-C films with column/inter-column structures. It is presumed that preferable graphitization occurred in the inter-column regions induced by electron irradiation.

关键词：无定形碳溅射石墨化低能电子注辐射毫微结构

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Flow Visualization around a Double Wedge Airfoil Model with Focusing Schlieren System

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Journal of Thermal Science 2006年第1期15卷 31-36页

作者： Masashi KASHITANI Yutaka yamaguchi Department of Aerospace Engineering National Defense Academy 1-10-20 Hashirimizu Yokosuka Kanagawa 239-8686Japan

In the present study, aerodynamic characteristics of the double wedge airfoil model were investigated in a transonic flow by using the shock tube as an intermittent wind tunnel. The driver and driven gases of the shock tube are dry air. The airfoil model of double wedge has the span of 58 mm, chord length c = 75 mm and its maximum thickness is 7.5 mm. The apex of the double wedge airfoil model is located on the 35% chord length from the leading edge. The range of hot gas Mach numbers are from 0.80 to 0.88, and the Reynolds numbers based on chord length are 3.11× 10^5- 3.49× 10^5, respectively. The flow visualizations were performed by the sharp focusing schlieren method which can visualize the three dimensional flow fields. The results show that the present system can visualize the transonic flowfield clearer than the previous system, and the shock wave profiles of the center of span in the test section are visualized

关键词： shock wave schlieren method transonic flow double wedge airfoil model

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Computer-generated holograms for 3D display(Invited Paper)

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Chinese Optics Letters 2009年第12期7卷 1079-1082页

作者： Hiroshi Yoshikawa Takeshi yamaguchi Department of Electronics and Computer Science Nihon University

We have been studying various types of computer-generated holograms for three-dimensional （3D） displays both for a real-time holographic video display and a hard copy, or a printed hologram. For the hard copy output, we have developed a direct fringe printer, which is achieved to print over 100 gigapixels computer-generated hologram with 0.44μm pitch. In this paper, we introduce our recent progresses on the rainbow hologram, the cylindrical holograms, and the disk hologram for 3D display.

关键词： Computer-generated holograms for 3D display Figure

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