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上海钢研 2003年第3期 83-87页

作者： Hideo Hata Ph.D.Hiroshi Yaguchi Masataka Shimoysusa masao toyama 秦添艳日本

前言丝棒产品应用十分广泛,如制造汽车和家用电器的部件。它们在制成最终产品前要经过二次或三次加工。随着近年降低成本和全球环保意识的加强。

关键词：热机械控制工艺丝材棒材 TMCP 再结晶颗粒尺寸沉淀相变材料开发

Utility of plasma D-dimer for diagnosis of venous thromboembolism after hepatectomy

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World Journal of Clinical Cases 2024年第2期12卷 276-284页

作者： Taiichiro Miyake Hiroaki Yanagimoto Daisuke Tsugawa Masayuki Akita Riki Asakura Keisuke Arai Toshihiko Yoshida Shinichi So Jun Ishida Takeshi Urade Yoshihide Nanno Kenji Fukushima Hidetoshi Gon Shohei Komatsu Sadaki Asari Hirochika toyama Masahiro Kido Tetsuo Ajiki Takumi Fukumoto Division of Hepato-Biliary-Pancreatic Surgery Department of SurgeryKobe University Graduate School of MedicineKobe 650-0017HyogoJapan

BACKGROUND Venous thromboembolism(VTE)is a potentially fatal complication of *** use of postoperative prophylactic anticoagulation in patients who have undergone hepatectomy is controversial because of the risk of postoperative ***,we hypothesized that monitoring plasma D-dimer could be useful in the early diagnosis of VTE after *** To evaluate the utility of monitoring plasma D-dimer levels in the early diagnosis of VTE after *** The medical records of patients who underwent hepatectomy at our institution between January 2017 and December 2020 were retrospectively *** were divided into two groups according to whether or not they developed VTE after hepatectomy,as diagnosed by contrast-enhanced computed tomography and/or ultrasonography of the lower *** factors,including demographic data and perioperative D-dimer values,were compared between the two *** operating characteristic curve analysis was performed to determine the D-dimer cutoff *** and multivariate analyses were performed using logistic regression analysis to identify significant *** In total,234 patients who underwent hepatectomy were,of whom(5.6%)were diagnosed with VTE following hepatectomy.A comparison between the two groups showed significant differences in operative time(529 vs 403 min,P=0.0274)and blood loss(530 vs 138 mL,P=0.0067).The D-dimer levels on postoperative days(POD)1,3,5,7 were significantly higher in the VTE group than in the non-VTE *** the multivariate analysis,intraoperative blood loss of>275 mL[odds ratio(OR)=5.32,95%confidence interval(CI):1.05-27.0,P=0.044]and plasma D-dimer levels on POD 5≥21μg/mL(OR=10.1,95%CI:2.04-50.1,P=0.0046)were independent risk factors for VTE after *** Monitoring of plasma D-dimer levels after hepatectomy is useful for early diagnosis of VTE and may avoid routine prophylactic anticoagulation in the

关键词： Hepatectomy Malignant tumor Postoperative complication D-dimer Early diagnosis Venous thromboembolism

Harpagometabolins Ⅰ and Ⅱ, Two New Metabolites from Harpagoside by Human Intestinal Bacteria

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Chinese Chemical Letters 2000年第9期11卷 779-782页

作者： Xiu Wei YANG Chen Ting ZOU masao HATTORI National Research Laboratory of Natural & Biomimetic Drugs, Peking University, Beijing 100083 Institute of Natural Products, toyama Medical & Pharmaceutical University 2630 Sugitani, toyama 930-01, Japan Natl. Res. Lab. Nat. Biomimetic D. Peking University Beijing 100083 China Institute of Natural Products Toyama Med. and Pharmaceutical Univ. 2630 Sugitani Toyama 930-01 Japan

Harpagoside, which is one main iridoid constituent of the dried roots of Scrophularia ningpoensis Hemsl., was biotransformated by bacteria isolated from human feeal flora a.d three metabolites were obtained. The structures of the metabolites, including two new alkaloids, named bar'Pagometabolins Ⅰ (l) and Ⅱ (2), and a known alkaloid acubinine B(3), were identified by chemical methods and the spectroscopic evidences.

关键词： Scrophularia ningpoensis Harpagoside harpagometabolin Ⅰ harpagometabolin Ⅱ acubinine B.

Preparation of titanium phosphate white pigments with titanium sulfate and their powder properties

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Journal of Advanced Ceramics 2014年第2期3卷 132-136页

作者： Hiroaki ONODA Syohei FUJIKADO Takeshi toyama Department of Informatics and Environmental Sciences Kyoto Prefectural University1-5Shimogamo Nakaragi-cyoSakyo-kuKyoto 606-8522Japan Department of Materials and Applied Chemistry College of Science and TechnologyNihon University1-8-14 Kanda-SurugadaiChiyoda-kuTokyo 101-8308Japan

Titanium oxide that has photocatalytic activity is used as white pigment for cosmetics.A certain degree of sebum on the skin is decomposed by the ultraviolet radiation in *** this work,as novel white pigment,titanium phosphates were synthesized with titanium sulfate and phosphoric acid for *** chemical composition,powder properties,photocatalytic activity,color phase,moisture retention,and smoothness were *** titanium phosphates had less photocatalytic activity to protect the sebum on the *** without heating and those heated at 100℃showed high reflectance in the range of visible *** prepared in Ti/P=3/2 had higher moisture retention than samples prepared in other Ti/P ratios.

关键词： white pigment titanium phosphates photocatalytic activity smoothness

Accelerated biodegradation of nitrophenols in the rhizosphere of Spirodela polyrrhiza

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Journal of Environmental Sciences 2012年第5期24卷 800-807页

作者： Risky Ayu Kristanti Masahiro Kanbe Tadashi toyama Yasuhiro Tanaka Kazuhiro Mori Interdisciplinary Graduate School of Medicine and Engineering University of Yamanashi 4-3-11 Takeda Kofu Yamanashi 400-8511 Japan

We investigated the biodegradation of 2-nitrophenol （2-NP）, 4-nitrophenol （4-NP）, and 2,4-dinitrophenol （2,4-DNP） in the rhizosphere of Spirodela polyrrhiza plants by conducting degradation experiments with three river water samples supplemented with each nitrophenol （NP）. We then isolated NP-degrading bacteria both from the S. polyrrhiza roots and from the river water. In the river water samples, removal of the three NP was accelerated in the presence of S. polyrrhiza plants. The three NPs persisted in an autoclaved solution with sterile plants suggests that NP removal was accelerated largely by bacterial NP biodegradation rather than by adsorption and uptake by the plants. We isolated 8 strains of NP-degrading bacteria： 6 strains from the S. polyrrhiza roots and 2 strains from river water without the plants. The 2-NP- and 2,4-DNP-degrading bacteria were isolated only from the S. polyrrhiza roots. The 4-NP- degrading bacteria different from those isolated from the river water samples were also found on S. polyrrhiza roots. The 2-NP- and 4-NP-degrading strains isolated from the roots utilized the corresponding NP （0.5 mmol/L） as the sole carbon and energy source. The 2,4-DNP-degrading strains isolated from the roots showed substantial 2,4-DNP-degrading activity, but the presence of other carbon and energy sources was required for their growth. The isolated NP-degrading bacteria from the roots must have contributed to the accelerated degradation of the three NPs in the rhizosphere of S. polyrrhiza. Our results suggested that rhizoremediation with S. polyrrhiza may be effective for NP-contaminated surface water.

关键词： Spirodela polyrrhiza rhizosphere nitrophenol biodegradation

Microstructural analyses of all-solid-state Li–S batteries using LiBH4-based solid electrolyte for prolonged cycle performance

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Journal of Energy Chemistry 2020年第11期29卷 424-429页

作者： Kazuaki Kisu Sangryun Kim Ryuga Yoshida Hiroyuki Oguchi Naoki toyama Shin-ichi Orimo Advanced Institute for Materials Research(WPI-AIMR) Tohoku UniversityKatahira 2-1-1Aoba-kuSendai 980-8577Japan Institute for Materials Research(IMR) Tohoku UniversityKatahira 2-1-1Aoba-kuSendai 980-8577Japan

Complex hydride materials have been widely investigated as potential solid electrolytes because they have good compatibility with the lithium metal anodes used in all-solid-state batteries. However, the development of all-solid-state batteries utilizing complex hydrides has been difficult as these cells tend to have short cycle lives. This study investigated the capacity fading mechanism of all-solid-state lithium–sulfur(Li–S) batteries using Li4(BH4)3I solid electrolytes by analyzing the cathode microstructure. Crosssectional scanning electron microscopy observations after 100 discharge–charge cycles revealed crack formation in the Li4(BH4)3I electrolyte and an increased cathode thickness. Raman spectroscopy indicated that decomposition of the Li4(BH4)3I solid electrolyte occurred at a constant rate during the cycling *** combat these effects, the cycle life of Li–S batteries was improved by increasing the amount of solid electrolyte in the cathode.

关键词： All-solid-state battery Complex hydride solid electrolyte Li metal anode Li–S battery Microstructure

Age-dependent changes in the association between sleep duration and impaired glucose metabolism

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World Journal of Diabetes 2017年第8期8卷 397-406页

作者： Kei Nakajima Kaname Suwa Kenji toyama School of Nutrition and Dietetics Faculty of Health and Social Services Kanagawa University of Human Services Yokosuka Department of Endocrinology and Diabetes Saitama Medical Center Saitama Medical University Saitama Health Promotion Corporation

AIM To investigate whether the association between sleep duration and impaired glucose metabolism varies among younger and older *** We reviewed data of self-reported habitual sleep duration per night, HbA1c levels, and clinically relevant factors in a cross-sectional checkup database of 75472 Japanese from the general population aged 20-79 years(51695 men and 23777 women). Associations of prediabetes(HbA1c ≥ 5.7% and/or diabetic pharmacotherapy) or diabetes(HbA1c ≥ 6.5% and/or diabetic pharmacotherapy) with short and long sleep durations compared with a reference sleep duration(7 h) were investigated by multivariate logistic regression analysis. We controlled for potential relevant confounders, including age, sex, and work duration per day according to younger and older *** As age advanced, sleep duration became longer and this increase in the 40 s and 50 s was two times greater in men than in women. This finding was accompanied by a deterioration in HbA1c levels. In subjects aged youngerthan 40 years(n = 32929), HbA1c levels were inversely and linearly correlated with sleep duration in both sexes. However, in subjects aged 40 years or older(n = 42543), HbA1c levels showed a non-linear relationship against sleep duration with a nadir at 7 h. Multivariate logistic regression analysis showed that in younger subjects, short durations of sleep(≤ 5 h and 6 h) were positively associated with prediabetes(both P < 0.001), but a long duration of sleep(≥ 8 h) was inversely associated with prediabetes(P < 0.001). These associations remained significant after adjustment for relevant confounders, including age, sex, and work duration per day(ORs = 1.20, 95%CI: 1.05-1.37, P < 0.001; ORs = 1.12, 95%CI: 1.02-1.24, P < 0.05; and ORs = 0.84, 95%CI: 0.72-0.99, P < 0.05, respectively). In contrast, in older subjects, besides an association of prediabetes with a short duration of sleep(≤ 5 h)(ORs = 1.12, 95%CI: 1.03-1.21, P < 0.01), diabetes was significant

关键词： Sleep Prediabetes Diabetes HbA1c Aging

Accelerated degradation of a variety of aromatic compounds by Spirodela polyrrhiza-bacterial associations and contribution of root exudates released from S. polyrrhiza

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Journal of Environmental Sciences 2010年第4期22卷 494-499页

作者： Hai Hoang Ning Yu Tadashi toyama Daisuke Inoue Kazunari Sei Michihiko Ike Division of Sustainable Energy and Environmental Engineering Osaka University Suita Osaka 565-0871 Japan Division of Applied Sciences Muroran Institute of Technology Muroran Hokkaido 050-8585 Japan

Removal experiments of phenol, aniline, 2,4-dichlorophenol, nonylphenol and bisphenol A （BPA） using Spirodela polyrrhiza- bacterial associations revealed that all compounds but BPA underwent accelerated removal. The mechanisms differed depending on the substrates. It was found that S. polyrrhiza has a great ability to release phenolic compound-rich root exudates, and the exudates seem to stimulate bacterial degradation of a variety of aromatic compounds.

关键词： accelerated biodegradation aromatic compounds rhizosphere root exudates Spirodela polyrrhiza

Acquisition of hyponymy relations for agricultural terms from a Japanese statutory corpus

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Information Processing in Agriculture 2014年第2期1卷 95-104页

作者： Makoto Nakamura Tomohiro Ohno Yasuhiro Ogawa Katsuhiko toyama Japan Legal Information Institute Graduate School of LawNagoya UniversityFuro-choChikusa-kuNagoya 464-8601Japan Information Technology Center Nagoya UniversityFuro-choChikusa-kuNagoya 464-8601Japan Graduate School of Information Science Nagoya UniversityFuro-choChikusa-kuNagoya 464-8601Japan

This paper,which aims to increment the vocabulary of an existing thesaurus using hyponymy relations,focuses on an agricultural thesaurus called *** main goal is to acquire AGROVOC-qualified candidates from the hyponymy relations of legal texts and *** propose a pattern-based approach to hyponymy relation *** experimental result showed that 222 and 868 candidates are extracted from statutory sentences with 67.1%precision and tables with 37.0%precision,respectively.

关键词： AGROVOC Japanese statutory corpus Legal text processing

Disruption of ectoplasmic specializations between Sertoli cells and maturing spermatids by anti-nectin-2 and anti-nectin-3 antibodies

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Asian Journal of Andrology 2008年第4期10卷 577-584页

作者： Yoshiro toyama Fumie Suzuki-Toyota Mamiko Maekawa Chizuru Ito Kiyotaka Toshimori Department of Anatomy and Developmental Biology Graduate School of Medicine Chiba University Chiba 260-8670Japan

Aim： To understand the biological functions of the ectoplasmic specializations between Sertoli cells and maturing spermatids in seminiferous epithelia. Methods： In order to disrupt the function of the ectoplasmic specializations, nectin-2, which is expressed at the specialization, was neutralized with anti-nectin-2 antibody micro-injected into the lumen of the mouse seminiferous tubule. Anti-nectin-3 antibody was also micro-injected into the lumen in order to neutralize nectin-3, which is expressed at the specialization. Results： The actin filaments at the specialization disappeared, and exfoliation of maturing spermatids was observed by electron microscopy. Conclusion： Nectin-2 was neutralized by anti-nectin-2 antibody and nectin-3 was neutralized by anti-nectin-3 antibody, respectively. Inactivated nectin-2 and nectin-3 disrupted the nectin-afadin-actin system, and finally the actin filaments disappeared. As a result, the specialization lost the holding function and detachment of spermatids was observed. One of the functions of the specialization seems to be to hold maturing spermatids until spermiation.

关键词： ectoplasmic specialization Sertoli cell spermatogenic cell testis actin nectin mice