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Isolated neutropenia caused by copper deficiency due to jejunal feeding and excessive zinc intake:A case report

World Journal of Clinical Cases 2021年第29期9卷 8825-8830页

作者： Hiromitsu Ohmori Hiroko Kodama Masahiko Takemoto Masami Yamasaki Tomio Matsumoto masao kumode Takafumi Miyachi Ryo Sumimoto Department of Pediatrics National Hospital Organization Yanai Medical CenterYanai 742-1352YamaguchiJapan Doctoral Program in Health and Dietetics Graduate School of Health SciencesTeikyo Heisei UniversityToshima-ku 170-8445TokyoJapan Department of Surgery National Hospital Organization Yanai Medical CenterYanai 742-1352YamaguchiJapan Department of Neurology National Hospital Organization Yanai Medical CenterYanai 742-1352YamaguchiJapan Department of Pediatrics Biwako Gakuen Kusatsu Medical and Welfare Center for Children and Persons with Severe Motor and Intellectual DisabilitiesKusatsu 525-0034ShigaJapan

BACKGROUND Percutaneous endoscopic gastrostomy with jejunal extension(PEG-J)is often used to treat patients with neurological impairment and difficulty in ***,these patients often develop copper *** report describes a case of isolated neutropenia,which is a rare manifestation of copper *** SUMMARY Our patient was a 19-year-old boy with neurological impairment and gastroesophageal *** received PEG-J feeding,including an enteral supplement containing copper and ***,as his serum zinc level was low(53μg/dL)at the age of 19 years and 2 mo,we changed to a zinc-rich supplement containing 22 mg/d of zinc and 1.0 mg/d of *** supplement comprised a mixture of isocal 1.0 junior(5 packs/d),Tezon[2 packs(250 mL)/d],and cocoa *** months later,he had neutropenia(606/mm^(3))with a serum copper level of 16μg/*** were no other manifestations of copper deficiency,including *** deficiency and neutropenia both improved following the administration of cocoa powder and *** In patients receiving long-term PEG-J feeds,white blood cell counts,hemoglobin,and serum levels of copper and zinc should be regularly monitored.

关键词： Percutaneous endoscopic gastrostomy with jejunal extension feeding Neutropenia Copper Zinc Deficiency Case report

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