检索结果-南通市图书馆

Castration-induced expression of caspase-1 in epithelia of accessory sex organs in male rats

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2001年第2期3卷 105-108页

作者： masao Izawa Mitunori Kimura Tomiko Yamada Makoto Saji Department of Biosignaling School of Life Science Faculty of Medicine Tottori University Yonago 683-8503 JapanDepartment of Neurobiology School of Life Science Faculty of Medicine Tottori University Yonago 683-8503 JapanDepartment of Biosignaling School of Life Science Faculty of Medicine Tottori University Yonago 683-8503 JapanDepartment of Neurobiology School of Life Science Faculty of Medicine Tottori University Yonago 683-8503 Japan

Aim: As an attempt to clarify the molecular basis of castration-induced apoptosis, this study was undertaken todemonstrate the expression of caspase-1 in male accessory sex organs of rats. Methods and results; cDNA of ratcaspase-1 was cloned by reverse transcription-polymerase chain reaction from the ventral prostates. The open readingframe predicts 402 amino acids, which shows more than 91% and 63% identity to those of mouse and human, respec-tively. Northern analyses demonstrated the presence of castration-induced up-regulation of the 1.6 kb transcript in theventral prostate and the seminal vesicles. Finally, the authors demonstrated the caspase-1 transcripts in the epithelia ofthese tissues by in situ hybridization analyses. Conclusion; Castration induces the expression of caspase-1 tran-scripts in the epithelia of ventral prostate and seminal vesicle. These observations suggest a possible role of caspase-1 inapoptosis in male accessory sex organs.

关键词： prostate seminal vesicles tissue involution apoptosis caspase-1 cDNA cloning castration epithelium rats

Effects of Asian dust events on atmospheric bacterial communities at different distances downwind of the source region

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2018年第10期30卷 133-139页

作者： Jonguk Park Pin-Fang Li Tomoaki Ichijo masao Nasu Nobuyasu Yamaguchi Graduate School of Pharmaceutical Sciences Osaka University1-6 Yamada-okaSuitaOsaka 565-0871Japan National Institutes of Biomedical Innovation Health and Nutrition7-6-8 Asagi Saito Ibaraki Osaka 567-0085 Japan College of Resources and Environmental Sciences China Agricultural University Beijing100193 China Faculty of Pharmacy Osaka Ohtani University3-11-1 Nishikiori-kita Tondabayashi Osaka 584-8540 Japan Osaka Institute of Public Health 1-3-69 Nakamichi Higashinari Osaka 537-0025 Japan

Aeolian dust particles arising from arid and semiarid zones are known to carry microbes by air currents. The effect of wind-borne bacteria on atmospheric bacterial population at various downwind distances from the dust source regions must be clarified, but has not yet been reported. This study monitored the bacterial abundance and community composition in outdoor aerosol samples in Beijing, China, which is close to the Asian dust source regions, and compared them with the results obtained in a distant region（Osaka, Japan）.The Asian dust collected in Beijing contained（4 ± 3） × 10^4 bacterial cells/m^3, approximately 4 times higher than in Osaka. On 15 April 2015, Beijing experienced severe Asian dust events with a 1000-fold increase in bacterial abundance, relative to non-Asian dust days. Dominant bacterial phyla and classes in Asian dust collected in Beijing were Actinobacteria, Bacilli and Acidobacteria, and the bacterial community composition varied more widely than in *** bacterial community compositions differed between the Beijing and Osaka dusts, even for the same Asian dust events. These results indicated that aerosol bacterial communities nearer the dust source are more affected by eolian dust than their distant counterparts.

关键词： Aeolian dust Amplicon sequencing Asian dust Bacterial community Bioaerosols

Thin film dynamics in coating problems using Onsager principle

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2018年第2期27卷 51-55页

作者：邸亚娜许现民周嘉嘉 masao Doi LSEC ICMSEC Academy of Mathematics and Systems Science Chinese Academy of Sciences School of Mathematical Sciences University of Chinese Academy of Sciences Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang University Center of Soft Matter Physics and Its Applications Beihang University Beijing Advanced Innovation Center for Biomedical Engineering Beihang University

A new variational method is proposed to investigate the dynamics of the thin film in a coating flow where a liquid is delivered through a fixed slot gap onto a moving substrate. A simplified ODE system has also been derived for the evolution of the thin film whose thickness hf is asymptotically constant behind the coating front. We calculate the phase diagram as well as the film profiles and approximate the film thickness theoretically, and agreement with the well-known scaling law as Ca2/3 is found.

关键词： Onsager principle thin films coating flows interfacial flows

A Consistent Time Level Implementation Preserving Second-Order Time Accuracy via a Framework of Unified Time Integrators in the Discrete Element Approach

在线全文

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2023年第3期134卷 1469-1487页

作者： Tao Xue YazhouWang masao Shimada David Tae Kumar Tamma Xiaobing Zhang School of Energy and Power Engineering Nanjing University of Science and TechnologyNanjing210094China'2Department of Mechanical EngineeringUniversity of Minnesota-Twin CitiesMinneapolis55455USA

In this work,a consistent and physically accurate implementation of the general framework of unified second-order time accurate integrators via the well-known GSSSS framework in the Discrete Element Method is *** improved tangential displacement evaluation in the present implementation of the discrete element method has been derived and implemented to preserve the consistency of the correct time level evaluation during the time integration process in calculating the algorithmic tangential *** numerical examples have been used to validate the proposed tangential displacement evaluation;this is in contrast to past practices which only seem to attain the first-order time accuracy due to inconsistent time level implementation with different algorithms for normal and tangential *** comparisons with the existing implementation and the superiority of the proposed implementation are given in terms of the convergence rate with improved numerical accuracy in ***,several schemes via the unified second-order time integrators within the framework of the GSSSS family have been carried out based on the proposed correct *** the numerical results demonstrate that using the existing state-of-the-art implementation reduces the time accuracy to be first-order accurate in time,while the proposed implementation preserves the correct time accuracy to yield second-order.

关键词： Computational dynamics time integration Discrete Element Method(DEM)

Fault-tolerant decentralized H-infinity control for multi-channel systems using homotopy method

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

控制理论与应用（英文版） 2007年第1期5卷 77-82页

作者： Ning CHEN Weihua GUI masao IKEDA School of Information Science ＆ Engineering Central South University Changsha Hunan 410083 China Graduate School of Engineering Osaka University Suita Osaka 565-0871 Japan

This paper considers a fault-tolerant decentralized H-infinity control problem for multi-channel linear time-invariant systems. The purpose is to design a decentralized H-infinity output feedback controller *** the given system and achieve a certain H-infinity performance requirement both in the normal situation and in the situation where any one of the local controllers fails. The designed problem is reduced to a feasibility problem of a set of bilinear matrix inequalities （BMIs）. An algorithm is proposed to solve the BMIs. First, the normal situation is considered where all the local controllers are functioning. The local controllers are obtained from a standard centralized H-infinity controller by using a homotopy method imposing a structural constraint progressively. Secondly, the above case is extended to the one where any one of the local controllers fails. We again use a homotopy method where the coefficient matrices of the failed controller are decreased progressively to zero. The efficiency of the proposed algorithm is demonstrated by an example.

关键词： Decentralized control H-infinity control Fault-tolerant Control BMI Homotopy method

Novel serum tumor marker, RCASl, in pancreatic diseases

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2005年第33期11卷 5199-5202页

作者： Koji Yamaguchi Munechika Enjoji Manabu Nakashima Makoto Nakamuta Takashi Watanabe masao Tanaka Department of Surgery and Oncology Graduate School of Medicine Kyushu University Japan Medicine Bioregulatory Sciences Graduate School of Medical Sciences Kyushu University Japan Department of Molecular Immunology Medical Institute of Bioregulation Faculty of MedicineKyushu UniversityJapan Department of Molecular Immunology Medical Institute of Bioregulation Faculty of Medicine Kyushu University Japan

AIM： As tumor markers for pancreatic carcinoma, carcinoembryonic antigen （CEA） and carbohydrate antigen （CA） 19-9 have been used, but the sensitivity and specificity are not enough for the diagnosis of pancreatic carcinoma. METHODS： A novel serum tumor marker, RCAS1, was compared with two conventional serum tumor markers, CEA （highly specific for pancreatic cancer） and CA 19-9 （highly sensitive for pancreatic cancer）, in 48 patients with pancreatic exocrine tumors. RESULTS： When the diagnosis of benign or malignant conditions was examined by one tumor marker, the sensitivity of RCAS1 alone （55%） was higher than that of CEA alone （27%） and the specificity of RCAS1 alone （92%） was greater than that of CA19-9 alone （78%）. When examined by a combination of two markers, the sensitivity of a combination of RCAS1 and CA19-9 （95%） was superior to those of CA19-9 alone （78%）, RCAS1 alone （55%, P = 0.002）, CEA alone （27%）（P〈0.001）, RCAS1 and CEA （59%） and CA19-9 and CEA （82%）. CONCLUSION： These results suggest that the combination of RCAS1 and CA19-9 is highly sensitive for pancreatic carcinoma.

关键词： RCASi CEA CA19-9 Pancreatic diseases

Surgical spacer placement and proton radiotherapy for unresectable hepatocellular carcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2010年第14期16卷 1800-1803页

作者： Shohei Komatsu Yuichi Hori Takumi Fukumoto masao Murakami Yoshio Hishikawa Yonson Ku Department of Surgery Division of Hepato-Biliary-Pancreatic Surgery Kobe University Graduate School of Medicine Kobe 650-0017 Japan Department of Radiology Hyogo Ion Beam Medical Center Tatsuno 679-5165 Japan

Few potentially curative treatment options exist apart from hepatic resection for patients with huge hepatocellular carcinoma (HCC). Proton radiotherapy is a promising new modality which has an inherent antitumor effect against HCC. However, the application of proton radiotherapy for tumors adjacent to the gastrointestinal tract is restricted because the tolerance dose of the intestine is extremely low. A novel two-step treatment was developed with surgical spacer placement and subsequent proton radiotherapy to administer proton radiotherapy with curative intent. This report presents a case of a patient with a huge unresectable HCC treated by this method who achieved disease-free survival of more than 2 years. This new strategy may potentially be an innovative and standard therapy for unresectable HCC in the near future.

关键词： Hepatocellular carcinoma Proton radio-therapy Particle radiotherapy Operative surgical procedures

Ni/Pd-based ohmic contacts to p-GaN through p-InGaN/p^(+)-GaN contacting layers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Semiconductors 2022年第9期43卷 81-86页

作者： Minglong Zhang masao Ikeda Siyi Huang Jianping Liu Jianjun Zhu Shuming Zhang Hui Yang School of Nano-Tech and Nano-Bionics University of Science and Technology of ChinaHefei 230026China Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of SciencesSuzhou 215123China

Specific contact resistance to p-GaN was measured for various structures of Ni/Pd-based metals and thin(20-30 nm thick)p-InGaN/p^(+)-GaN contacting *** effects of surface chemical treatment and annealing temperature were *** optimal annealing temperature was determined to be 550°C,above which the sheet resistance of the samples de-graded considerably,suggesting that undesirable alloying had ***-containing metal showed~35%lower com-pared to that of single *** thin(2-3.5 nm thick)p-InGaN contacting layers grown on 20-25 nm thick p^(+)-GaN layers exhib-ited one to two orders of magnitude smaller values of compared to that of p^(+)-GaN without *** current density de-pendence of,which is indicative of nonlinearity in current-voltage relation,was also *** lowest achieved through this study was 4.9×10^(-5)Ω·cm^(2)@J=3.4 kA/cm^(2).

关键词： GaN ohmic contact specific contact resistance

在线全文

学校读者我要写书评

暂无评论

不确定多通道奇异大系统分散鲁棒H_∞控制

控制理论与应用 2007年第2期24卷 322-328页

作者：陈宁桂卫华 IKEDA masao 中南大学信息科学与工程学院湖南长沙410083 大阪大学工学研究科

研究不确定多通道奇异系统的鲁棒分散H_∞控制问题,假定不确定性是时不变、范数有界,且存在于系统和控制输入矩阵中．主要考虑分散H_∞输出反馈控制问题．推导出了使不确定多通道奇异系统能鲁棒稳定且满足一定的性能指标的充分必要条件... 详细信息

研究不确定多通道奇异系统的鲁棒分散H_∞控制问题,假定不确定性是时不变、范数有界,且存在于系统和控制输入矩阵中．主要考虑分散H_∞输出反馈控制问题．推导出了使不确定多通道奇异系统能鲁棒稳定且满足一定的性能指标的充分必要条件,没有等式约束的非线性矩阵不等式条件,采用两步同伦法迭代来求解非线性矩阵不等式(NMI),首先,通过逐步对控制器的系数矩阵加上结构限制,计算出当确定性不存在时的标称系统的分散H_∞控制器．然后,逐步改变标称系统分散控制器的系数,计算出不确定性参数存在时的分散鲁棒控制器．在每一阶段,每一次迭代过程中,通过交替固定NMI的一个变量,使NMI转变为线性矩阵不等式(LMI)．数值例子说明了本文提出的方法的有效性．

关键词：分散H∞控制奇异系统参数不确定性同伦法非线性矩阵不等式 LMI