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Passive Control of Condensation Shock Wave in Prandtl-Meyer Expansion Flow

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Journal of Thermal Science 2003年第1期12卷 20-26页

作者： Shigeru Matsuo masanori tanaka Toshiaki Setoguchi Heuy-Dong Kim Department of Mechanical Engineering Saga UniversityDepartment of Mechanical Engineering Saga UniversityDepartment of Mechanical Engineering Saga UniversitySchool of Mechanical Engineering College of Natural Science Andong National University 388 1 Honjo-machi Saga-shi Saga 840-8502 Japan1 Honjo-machi Saga-shi Saga 840-8502 Japan 1 Honjo-machi Saga-shi Saga 840-8502 Japan Song-Cheon Dong Andong Kyung-Pook Korea

In this paper, the effects of the passive technique by using the slotted wall on the characteristics of a condensation shock wave generated in a Prandtl-Meyer flow were investigated experimentally. Furthermore, in order to clarify the variation of condensation properties in the flow field, Navier-Stokes equations were solved numerically using a 3rd-order MUSCL type TVD finite-difference scheme with a second-order fractional-step for time integration. Baldwin-Lomax model was used as a turbulence model in the computations. From experimental results, it was found that the shock strength on the slotted wall became weak in comparison with no passive case (solid wall), and the present passive technique was the most effective when a foot of the condensation shock wave was located at the middle of slotted wall. Furthermore, it was confirmed numerically that the passive technique was also effective for the unsteady condensation shock wave.

关键词： compressible flow Prandtl-Meyer flow condensation shock wave numerical simulation.

Generation of Overpressure due to Condensation in Moist Air Jet

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Journal of Thermal Science 2007年第2期16卷 145-148页

作者： Yumiko OTOBE Hideo KASHIMURA Shigeru MATSUO masanori tanaka Toshiaki SETOGUCHI Kitakyushu National College of Technology 5-20-1 ShiiKokuraminamiKitakyushuJapan Saga University 1HonjoSagaJapan

In the present study, a computational fluid dynamics method has been applied to investigate the effects of initial degree of supersaturation at reservoir condition on under-expanded sonic jet structures, such as Mach disk location and diameter, barrel shock wave and jet boundary. The axisymmetric nozzle geometry investigated was a converging nozzle with straight part. As a result, it was found that the overpressures due to condensation generate and the characteristics of flow with generation of overpressure due to condensation in the jet were different from those without condensation.

关键词： compressible flow axisymmetric flow sonic jet Mach disk condensation humidity overpressure

A Study of Under-expanded Moist Air Jet Impinging on a Flat Plate

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Journal of Thermal Science 2005年第4期14卷 334-340页

作者： Yumiko OTOBE Shigeru MATSUO masanori tanaka Hideo KASHIMURA Heuy-Dong KIM Toshiaki SETOGUCHI Department of Control and Information Systems Engineering Kitakyushu National College of Technology5-20-1ShiiKokuraminami-kuKitakyushu-shiFukuoka 802-0985Japan Department of Mechanical Engineering Saga University1Honjo-machiSaga-shiSaga 840-8502Japan School of Mechanical Engineering College of Natural ScienceAndong National University388Song Cheon DongAndongKyung PookKorea

When a gas expands through a convergent nozzle in which the ratio of the ambient to the stagnation pressures is higher than that of the critical one, the issuing jet from the nozzle is under-expanded. If a flat plate is placed normal to the jet at a certain distance from the nozzle, a detached shock wave is formed at a region between the nozzle exit and the plate. In general, supersonic moist air jet technologies with non-equilibrium condensation are very often applied to industrial manufacturing processes. In spite of the importance in major characteristics of the supersonic moist air jets impinging to a solid body, its qualitative characteristics are not known satisfactorily. In the present study, the effect of the non-equilibrium condensation on the under-expanded air jet impinging on a vertical flat plate is investigated numerically in the case with non-equilibrium condensation, frequency of oscillation for the flow field becomes larger than that without the non-equilibrium condensation, and amplitudes of static pressure become small compared with those of dry air. Furthermore, the numerical results are compared with experimental ones.

关键词： compressible flow non-equilibrium condensation impinging jet simulation.

Effect of Axisymmetric Sonic Nozzle Geometry on Characteristics of Supersonic Air Jet

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Journal of Thermal Science 2004年第2期13卷 121-126页

作者： Shigeru MATSUO masanori tanaka Yumiko OTOBE Hideo KASHIMURA Heuy-Dong KIM Toshiaki SETOGUCHI Department of Mechanical Engineering Saga University 1 Honjo-machi Saga-shi Saga 840-8502 Japan Department of Control and Information Systems Engineering Kitakyushu National College of Technology 5-20-1 Shii Kokuraminami-ku Kitakyushu-shi Fukuoka 802-0985 Japan School of Mechanical Engineering College of Natural Science Andong National University 388 Song-Cheon Dong Andong Kyung-Pook Korea

The effect of nozzle geometry on sonic line and characteristics of supersonic air jet was studied. Computational fluid dynamics was applied in this study. The axisymmetric nozzle geometries investigated were two different contour converging nozzles, two different conically converging sharp-edged nozzles and a sharp-edged orifice. The results show that the supersonic jet structure, sonic line and streamlines in supersonic jet are strongly influenced by the nozzle geometry, and the total pressure loss increases with the increase of Mach disk diameter. The present numerical simulation is an effective tool to evaluate compressible flows in supersonic air jet.

关键词： compressible flow supersonic jet non-equilibrium condensation simulation.

^(18)F-FDG PET/CT imaging for a gastrointestinal mantle cell lymphoma with multiple lymphomatous polyposis

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World Journal of Gastroenterology 2014年第17期20卷 5141-5146页

作者： Makoto Saito Masaya Miyazaki Mishie Tanino Shinya tanaka Kencho Miyashita Koh Izumiyama Akio Mori Tatsuro Irie masanori tanaka Masanobu Morioka Eriko Tsukamoto Department of Internal Medicine and Hematology Aiiku HospitalSapporo 064-0804Japan Department of Cancer Pathology Hokkaido University Graduate School of MedicineSapporo 060-8638Japan Department of Gastroenterology Aiiku HospitalSapporo 064-0804Japan Department of Nuclear Medicine Central CI ClinicSapporo 060-0042Japan

Multiple lymphomatous polyposis(MLP)is an uncommon type of gastrointestinal lymphoma characterized by the presence of multiple polyps along the gastrointestinal *** of this entity is in fact considered the counterpart of gastrointestinal tract involvement for mantle cell lymphoma(MCL).To our knowledge,there have been no reports on[fluorine-18]-fluorodeoxy-glucose(18F-FDG)-positron emission tomography(PET)/computed tomography(CT)imaging for gastrointestinal MCL with *** present the results of 18F-FDG PET/CT imaging in a patient with gastrointestinal tract involvement of MCL showing continuous MLP from the stomach to the rectum and intestinal ***-PET/CT findings were false negative in typical MLP spreading widely over the gastrointestinal tract,but uptake was noted in large lesions with deep infiltration considered atypical as *** FDG-PET/CT imaging,the Ki-67proliferative index,which is a cell proliferation marker,showed neither correlation with the presence of uptake nor the maximum standardized uptake value.

关键词： 18F-fluorodeoxy-glucose-positron emission tomography/computed tomography imaging Mantle cell lymphoma Multiple lymphomatous polyposis Gastrointestinal tract Ki-67 proliferative index

Acquired hemophilia A in solid cancer: Two case reports and review of the literature

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World Journal of Clinical Cases 2018年第14期6卷 781-785页

作者： Makoto Saito Reiki Ogasawara Koh Izumiyama Akio Mori Takeshi Kondo masanori tanaka Masanobu Morioka Masahiro Ieko Department of Internal Medicine and Hematology Aiiku Hospital Department of Internal Medicine Health Sciences University of Hokkaido

Acquired hemophilia A （AHA） is a rare, hemorrhagic autoimmune disease, whose pathogenesis involves reduced coagulation factor Ⅷ （FⅧ） activity related to the appearance of inhibitors against FⅧ. Common etiological factors include autoimmune diseases, ma-lignancy, and pregnancy. We report two cases of AHA in solid cancer. The first case is a 63-year-old man who developed peritoneal and intestinal bleeding after gastrectomy for gastric cancer. He was diagnosed with AHA, and was treated with prednisone, followed by cyclophosphamide. In the second case, a 68-year-old man developed a subcutaneous hemorrhage. He was diagnosed with AHA in hepatocellular carcinoma on CT imaging, and treated with rituximab alone. Hemostasis was achieved for both patients without bypassing agents as the amount of inhibitors was reduced and eradicated. However, both patients died within 1 yeardue to cancer progression. Successful treatment for AHA in solid cancer can be diffcult because treatment of the underlying malignancy is also required.

关键词： Acquired hemophilia A Coagulation factor Ⅷ Solid cancer Gastric cancer Hepatocellular carcinoma Case report

ALK-positive anaplastic large cell lymphoma presenting multiple lymphomatous polyposis: A case report and literature review

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World Journal of Clinical Cases 2019年第15期7卷 2049-2057页

作者： Makoto Saito Koh Izumiyama Reiki Ogasawara Akio Mori Takeshi Kondo masanori tanaka Masanobu Morioka Kencho Miyashita Mishie Tanino Department of Internal Medicine and Hematology Aiiku HospitalSapporo 0640804Japan Department of Gastroenterology Aiiku HospitalSapporo 0640804Japan Department of Surgical Pathology Asahikawa Medical University Hospital(formerly Department of Cancer PathologyHokkaido UniversityFaculty of Medicine)Asahikawa 0788510Japan

BACKGROUND Anaplastic large cell lymphoma(ALCL)is a type of T-cell lymphoma that can be divided into two categories:anaplastic lymphoma kinase-positive(ALK+)and *** ALK+ALCL is *** lymphomatous polyposis(MLP)is thought to be a representative form of gastrointestinal lesion in mantle cell lymphoma,and T-cell lymphomas seldom show this ***,we report the first known case of ALK+ALCL with gastroduodenal involvement to present with *** SUMMARY The patient was a 43-year-old man who was complained of a mass in the left inguinal area and was performed open ***+ALCL was diagnosed *** tomography scan demonstrated multiple lymph node lesions in the abdomen-pelvis/inguinal region,and scattered nodular lesions in both lung *** did not complain of gastrointestinal ***,esophagogastroduodenoscopy identified MLP lesions from the antrum of the stomach to the descending portion of the duodenum and mild thickened folds on the corpus of the stomach,and biopsy showed invasion of ALK+*** treated this patient with six cycles of CHOEP(Cyclophosphamide,Doxorubicin,Vincristine,Etoposide,and Prednisone)*** the conclusion of treatment,there was complete *** white scars were found on the stomach,endoscopically consistent with a remission image of *** endoscopic features of this case were thought to be similar to those of *** The macroscopic/endoscopic features of gastrointestinal ALK+ALCL may be more similar to those of B-cell lymphomas rather than T-cell lymphomas.

关键词： Anaplastic large-cell lymphoma Anaplastic lymphoma kinase Multiple lymphomatous polyposis T-cell lymphoma Gastrointestinal involvement

MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1

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Oncology Research 2024年第3期32卷 463-476页

作者： Hur SUN masanori KAWANO TATSUYA IWASAKI ICHRO ITONAGA YUTA KUBOTA HROSHI TSUMURA KAZUHRO tanaka Department of Orthopaedic Surgery Faculty of MedicineOita UniversityOita879-5503Japan

An important factor in the emergence and progre sion of osteosarcoma(OS)is the dysregulated expression of microRNAs(miRNAs).Transcription factor 7-like 1(TCF7LI),a member of the T cell factor/lymphoid enhancer factor(TCF/LEF)transcription factor family,interacts with the Wnt signaling pathway regulator β-catenin and acts as a DNA-specific binding *** study sought to elucidate the impact of the interaction between miR 3293p and TCF7L1 *** growth and apoptosis of OS and analyze the regulatory expression relationship between miRNA and mRNA in osteosarcoma cells using a variety of ***329-3p was significantly downregulated,while TCF7L1 was considerably up-regulated in all examined OS cell ***,a clinical comparison study was performed using the TCGA ***,the regulatory relationship between miR-329-3p and TCF7L1 on the proliferation and apoptosis of OS cells was verified through in vitro and in vivo *** miR 329-3p was transfected into the OS cell line,the expression of TCF7L1 decreased,the proliferation of OS cells was inhibited,the cytoskeleton disintegrated,and the nucleus condensed to fom apoptotic *** expression of proteins that indicate apoptosis increased *** cell cycle was arrested in the G0/G1 phase,and the G1/S transition was *** introduction of miR 3293p also inhibited downstream Cyclin D1 of the Wnt *** experiments indicated that the overexpression of miR-329-3p signi ficanly inhibited the growth of OS xenografts in nude mice,and the expression of TCF7L1 and C-Myc in tumor tssues *** 329-3p was significantly reduced in OS cells and played a suppressive role in tumorigenesis and proliferation by targeting TCF7L1 both in vitro and in *** cell cycle arrest and pathway inhibition were observed upon the regulation of TCF7LI by miR *** these results,it can be inferred that miR.3293p exerts anticancer efects in osteosarcom

关键词： MiR-329-3p TCF7L1 Wnt/β-catenin pathway Osteosarcoma Proliferation

Correction: MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1

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Oncology Research 2024年第8期32卷 1369-1370页

作者： HUI SUN masanori KAWANO TATSUYA IWASAKI ICHIRO ITONAGA YUTA KUBOTA HIROSHI TSUMURA KAZUHIRO tanaka Department of Orthopaedic Surgery Faculty of MedicineOita UniversityOita879-5503Japan

In the article‘MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1’(Oncology Research,2024,Vol.32,No.3,pp.463−***:10.32604/or.2023.044085),there was an error in the compilation of *** have revised Fig.8D to correct this error.A corrected version of Fig.8 is *** correction does not change any results or conclusions of the *** apologize for any inconvenience caused.

关键词： osteosarcoma correction revised