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室内设计与装修 2014年第4期 56-59页

作者： masamichi Katayama coco

日本设计公司Wonderwall最近为雷克萨斯——日本汽车制造商丰田公司的豪车品牌设计了一个独特的项目，即位于日本东京的“IntersectbyLexus”。店铺于去年夏天开业，它是该品牌的第一个不卖任何汽车的旗舰店。这个店既不是经销商也不是... 详细信息

日本设计公司Wonderwall最近为雷克萨斯——日本汽车制造商丰田公司的豪车品牌设计了一个独特的项目，即位于日本东京的“IntersectbyLexus”。店铺于去年夏天开业，它是该品牌的第一个不卖任何汽车的旗舰店。这个店既不是经销商也不是传统意义的零售空间，而被认为是多功能的社交空间。在这里人们不用坐在车上即能获得雷克萨斯的驾驭体验，人们通过室内设计、时尚、文化、电影、音乐和技术的多角度表达，来与雷克萨斯取得共鸣。

关键词：雷克萨斯旗舰店 INTER 汽车制造商生活品牌设计日本东京丰田公司

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Bobath疗法对中风后成人患者作用的研究

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Bobath疗法对中风后成人患者作用的研究

第六届北京国际康复论坛——主论坛

作者： masamichi FURUSAWA Department of Rehabilitation Bobath Memorial Hospital

＜正＞研究目的:IBITA于1995年定义的Bobath疗法概念为在对因中枢神经系统病变造成的功能,运动和张力紊乱的患者进行评价和治疗时使用的一种解决问题的方法。在Bobath疗法的治疗过程中,姿势控制与姿势肌张力的训练是功能重建的基础。从... 详细信息

＜正＞研究目的:IBITA于1995年定义的Bobath疗法概念为在对因中枢神经系统病变造成的功能,运动和张力紊乱的患者进行评价和治疗时使用的一种解决问题的方法。在Bobath疗法的治疗过程中,姿势控制与姿势肌张力的训练是功能重建的基础。从历史上来说,我们已主动的将运动学习和系统理论合并入Bobath

关键词： Bobath定义中风步行功能手功能吞咽功能面部表情慢性病例

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用锂离子充电电池的无接触导线的有轨电车

国外铁道车辆 2005年第5期42卷 19-22页

作者： masamichi OGASA 汪美玉

根据有轨电车的运行特点,提出了不采用高架线供电后对车载储电器的要求和无接触导线电车及车载锂离子电池的技术要求,且进行了样车试运行,并验证了技术条件。

关键词：有轨电车无接触导线充电电池日本

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A Study of SIC-Nanoparticles Porous Layer Formed on SIC-DPF Wall for Soot Oxidation

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A Study of SIC-Nanoparticles Porous Layer Formed on SIC-DPF ...

The FISITA 2012 World Automotive Congress--Volume 1：Advanced Internal Combustion Engines

作者： Keita Ishizaki Shinichi Tanaka Atsushi Kishimoto masamichi Tanaka Naoki Ohya Nobuhiro Hidaka Automobile R&D Center.Honda R&D Co. LtdTochigiJapan New Technology Research Laboratory.Sumitomo Osaka Cement Co. LtdChibaJapan

The pore structure of DPF is known to have a significant effect on filtration efficiency,pressure drop,and soot *** is reported that the formation of a nanoparticle porous layer on the surface of the DPF inlet wall promotes soot oxidation[1-3].However,the correlation between pore size in the nanoparticle layer and soot oxidation performance,the effect of the layer in actual use environments,and the oxidation mechanism involved have not yet been *** research discussed in this paper therefore formed SiC nanoparticle porous layers of various pore sizes on the inlet wall surfaces of SiC-DPF(creating what will be termed"NPLDPF"here)using the dip-coating method|4|.The NPL thickness was set at 20μm to help enable uniform coating samples to be *** regard to filter pressure drop without soot loading,results for a bare DPF and a Pt/γ-AlO-eoated DPF(catalyzed DPF:Pt=1 g/L)were virtually *** the NPL-DPF,pressure drop increased as pore size was *** contrast,in the case of pressure drop following soot loading(3 g/L).despite the fact that results for pressure drop for the NPL-DPF were higher than those for the bare DPF,they were lower than those for the catalyzed *** is possible to stop deep-bed filtration by forming a nanoparticle porous layer on the surface of the DPF inlet wall[1.5].With regard to soot oxidation performance,the T80 of an NPL-DPF(NPL pore size=350 nm)was found to be40%lower than that of a bare DPF and identical to that of a catalyzed *** addition,reducing the NPL pore size enhanced soot oxidation performance.X-ray photoelectron spectra(XPS),transmission electron microscopy(TEM),andhydrogen temperature-programmed desorption(H2-TPD)results indicated that the vSiC nanoparticle surface was covered by a 5 am SiO oxide *** was found that these oxidized SiC nanoparticles desorbed oxygen at around 450℃.This desorbed oxygen promoted the oxidation of diesel *** addition,the filtration efficiency of the NPL-DPF wi

关键词： Diesel vehicle Partieulate-emissions Paniculate filters Sootoxidation Desorhed oxygen

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日本的海洋污染与对策

环境科学动态 1989年第10期 24-26页

作者： masamichi Murakawa 蒲家彬

日本处在一片海洋的环抱之中,沿海有许多美丽的海湾和海滩,并且有多种海洋生物。但是在经济迅速增长的1960～1970年间,日本周围海域的污染也变得严重起来。沿海鱼类受到严重危害,一些海水浴场也被迫关闭。为了解决这些问题,政府实行了... 详细信息

日本处在一片海洋的环抱之中,沿海有许多美丽的海湾和海滩,并且有多种海洋生物。但是在经济迅速增长的1960～1970年间,日本周围海域的污染也变得严重起来。沿海鱼类受到严重危害,一些海水浴场也被迫关闭。为了解决这些问题,政府实行了海水质量监测,并开始实施了各项对策以对付污染,海水的质量才得到了一定的改善。监测系统在日本,海水质量的监测最初是由国家的47个县、地政府机构执行的,大约设置了2,2000个站位。

关键词：日本海洋污染防治

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InGaAsP激光器自发辐射中高能尾处的光谱烧孔及热载流子驰豫

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半导体光电 1983年第1期 55-56页

作者： masamichi Yamanishi ,屈积建

我们根据声学测量指出,在长波长InGaAsP激光器的有源层中存在较大的光学损耗,这种损耗在阈值电流附近达到饱和。这种可饱和吸收可用自旋分裂带到重空穴带(S-H)的跃迁来解释。在本文中,我们给出有关四元激光器自发辐射光谱中高能尾处的... 详细信息

我们根据声学测量指出,在长波长InGaAsP激光器的有源层中存在较大的光学损耗,这种损耗在阈值电流附近达到饱和。这种可饱和吸收可用自旋分裂带到重空穴带(S-H)的跃迁来解释。在本文中,我们给出有关四元激光器自发辐射光谱中高能尾处的烧孔结果,可以认为这是可饱和S—H带问吸收的又一证据。还给出关于热载流子驰豫的理论结果,它可以解释目前观察到的烧孔现象和四元发光二极管的增

关键词：驰豫自发辐射空穴自发发射 InGaAsP 光激射器电子器件激光器载流子(半导体) 热载流子

Tumor-derived insulin-like growth factor-binding protein-1 contributes to resistance of hepatocellular carcinoma to tyrosine kinase inhibitors

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Cancer Communications 2023年第4期43卷 415-434页

作者： Hiroyuki Suzuki Hideki Iwamoto Takahiro Seki Toru Nakamura Atsutaka Masuda Takahiko Sakaue Toshimitsu Tanaka Yasuko Imamura Takashi Niizeki Masahito Nakano Shigeo Shimose Tomotake Shirono Yu Noda Naoki Kamachi Miwa Sakai Kazutoyo Morita masamichi Nakayama Tomoharu Yoshizumi Ryoko Kuromatsu Hirohisa Yano Yihai Cao Hironori Koga Takuji Torimura Division of Gastroenterology Department of MedicineKurume University School of MedicineKurume CityFukuokaJapan Liver Cancer Research Division Research Center for Innovative Cancer TherapyKurume UniversityKurume CityFukuokaJapan Iwamoto Internal Medicine Clinic Kitakyushu CityFukuokaJapan Department of Microbiology Tumor and Cell biologyKarolinska InstitutetStockholmSweden Department of Surgery and Science Graduate School of Medical ScienceKyushu UniversityFukuoka CityFukuokaJapan Department of Pathology Kurume University School of MedicineKurume CityFukuokaJapan

Background:Antiangiogenic tyrosine kinase inhibitors(TKIs)provide one of the few therapeutic options for effective treatment of hepatocellular carcinoma(HCC).However,patients with HCC often develop resistance toward antiangiogenic TKIs,and the underlying mechanisms are not *** aim of this study was to determine the mechanisms underlying antiangiogenic TKI resistance in ***:We used an unbiased proteomic approach to define proteins that were responsible for the resistance to antiangiogenic TKIs in HCC *** evaluated the prognosis,therapeutic response,and serum insulin-like growth factor-binding protein-1(IGFBP-1)levels of 31 lenvatinib-treated HCC *** on the array of results,a retrospective clinical study and preclinical experiments using mouse and human hepatoma cells were ***,in vivo genetic and pharmacological gain-and loss-of-function experiments were ***:In the patient cohort,IGFBP-1 was identified as the signaling molecule with the highest expression that was inversely associated with overall ***,antiangiogenic TKI treatment markedly elevated tumor IGFBP-1 levels via the hypoxia-hypoxia inducible factor ***-1 stimulated angiogenesis through activation of the integrinα5β1-focal adhesion kinase ***,loss of IGFBP-1 and integrinα5β1 by genetic and pharmacological approaches re-sensitized HCC to lenvatinib ***:Together,our data shed light onmechanisms underlying acquired resistance of HCC to antiangiogenic *** TKIs induced an increase of tumor IGFBP-1,which promoted angiogenesis through activating the IGFBP-1-integrinα5β1 *** data bolster the application of a new therapeutic concept by combining antiangiogenic TKIs with IGFBP-1 inhibitors.

关键词： hepatocellular carcinoma hypoxia IGFBP-1 lenvatinib molecular targeting resistance tyrosine kinase inhibitors

Low-Cost Dye-Sensitized Solar Cells Based on Interconnected FTO-Activated Carbon Nanoparticulate Counter Electrode Showing High Efficiency

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材料科学与工程（中英文A版） 2015年第9期5卷 361-368页

作者： Chandana Sampath Kumara Ranasinghe Eranji Nirmada Jayaweera Gamaralalage Rajanya Ashoka Kumara Rajapakse Mudiyanselage Gamini Rajapakse Herath Mudiyanselage Navarathna Bandara masamichi Yoshimura Department of Chemistry Faculty of Science University of Peradeniya Peradeniya 20400 Sri Lanka Postgraduate Institute of Science University of Peradeniya Peradeniya 20400 Sri Lanka Graduate School of Engineering Toyota Technological Institute 2-12-1 Hisakata Tempaku-ku Nagoya 468-8511 Japan

Pleomorphic Adenoma Consisting of Multiple Cysts with Squamous Epithelial Lining: Findings on MRI, FNAC, and Histopathological Examination

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Open Journal of Stomatology 2021年第6期11卷 221-230页

作者： Hiroshi Yamamoto Sakurako Yamaguchi Erika Iwai Yukiko Iizuka Shu Fushimi Kunio Hayashi Takumi Kondo Satoshi Tokunaga Masaaki Suemitsu Takashi Kaneda Kayo Kuyama masamichi Komiya Department of Oral Surgery Nihon University School of Dentistry at Matsudo Chiba Japan Department of Radiology Nihon University School of Dentistry at Matsudo Chiba Japan Department of Pathology Nihon University School of Dentistry at Matsudo Chiba Japan

The incidence of pleomorphic adenoma (PA) of the minor salivary glands is reported to be 10%, and while the histological findings in PA can be diverse, keratin-filled cysts lined by squamous epithelium are rarely reported. The condition can, however, present with cyst formation in some cases. We review a rare case of pleomorphic adenoma in the buccal mucosa that involved the formation of multiple squamous epithelium-lined cysts in a 69-year-old woman. Magnetic resonance imaging (MRI), fine needle aspiration cytology, and histopathological examination were performed. Physical examination revealed a painless, mobile, elastic hard mass in the right buccal mucosa, measuring 2.5 × 1.0 cm. The MRI revealed a well-defined lesion with different signal intensities in the medial and distal regions of the right cheek. The medial side of the lesion showed a low signal intensity on T1-weighted imaging (T1WI) and T2-weighted imaging (T2WI), while the distal side showed a low signal intensity on T1WI, and a high signal intensity on T2WI and short tau inversion recovery (STIR) imaging. Fine needle aspiration of the lesion was performed under local anesthesia and a cytological diagnosis of an epidermoid or dermoid cyst was made. The tumor was completely resected under local anesthesia combined with intravenous sedation. The histopathological examination demonstrated the proliferation of atypical tumor cells with poor atypia and the formation of glandular, alveolar, large, and small cysts. The cysts were lined by keratinized squamous epithelial cells, their cavities were filled with keratinous material, and foreign body reaction was observed after rupture. Histopathological evaluation led to the diagnosis of pleomorphic adenoma. The patient had no evidence of recurrence, 2 years and 3 months after the surgery. In conclusion, the presence of multiple cysts lined by squamous epithelium can pose a significant diagnostic challenge in patients with PA. It is important to make the correct

关键词： Salivary Gland Tumor Pleomorphic Adenoma Cystic Formation