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Prevalence of Chronic Pain, Especially Headache, and Relationship with Health-Related Quality of Life in Middle-Aged Japanese Residents

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Health 2016年第1期8卷 116-124页

作者： Junko Mitoma masami Kitaoka Hiroki Asakura Enoch Olando Anyenda Daisuke Hori Nguyen Thi Thu Tao Toshio Hamagishi Koichiro Hayashi Fumihiko Suzuki Yukari Shimizu Hiromasa Tsujiguchi Yasuhiro Kambayashi Yuri Hibino Tadashi Konoshita Takiko Sagara Aki Shibata Hiroyuki Nakamura Department of Environmental and Preventive Medicine Graduate School of Medical Science Kanazawa University Ishikawa Japan Third Department of Internal Medicine Fukui University School of Medicine Fukui Japan

The aim of this study was to evaluate the prevalence of chronic pain (CP) and the relationship between CP, especially headache adjusted for CP at other sites, and health-related quality of life (HRQoL) in middle-aged Japanese residents. We examined the prevalence of CP (defined as pain persisting for 3 months or more) and HRQoL (SF-36) in 1117 middle-aged residents of Japan. We assessed the eight dimensions of health status and the 3 component SF-36 summary score to evaluate HRQoL. The prevalence of CP was 15.3% among men and 15.1% among women. Multiple linear regression analysis demonstrated that lumbar pain (p β = -0.132), knee pain (p β = -0.115), foot pain (p = 0.042, β = -0.065), and age (p β = -0.154) were independently correlated with a lower physical component score (PCS). Older age (ppβ = -0.096), knee pain (p β = -0.109), upper limb pain (p β = -0.098), and lumbar pain (p = 0.022, β = -0.077) all showed a significant negative correlation with MCS. The presence of chronic headache (p = 0.011, β = -0.082) was the only factor significantly correlated with a lower role component score (RCS). We identified a negative correlation between chronic headache and RCS, unlike the relation between musculoskeletal pain and PCS or MCS, suggesting that RCS was an independently influenced by CP differently from PCS or MCS in Japanese residents.

关键词： Quality of Life Chronic Pain Headache SF-36 Pain

多机构回顾性分析FDG PET／CT在预测下咽鳞状细胞癌肺转移患者生存中的作用

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中华核医学与分子影像杂志 2018年第3期38卷 226-227页

作者：唐军上海交通大学医学院附属苏州九龙医院核医学科 215021

[摘要]目的研究^18F-脱氧葡萄糖（FDG） PET/CT显像最大标准摄取值（SUVmax）与来自2家机构的下咽鳞状细胞癌患者长期随访后总生存率间可能存在的相关性，分析SUVmax与几个生存状态间的关系，包括无肺转移生存。方法81例患者的生存率用... 详细信息

[摘要]目的研究^18F-脱氧葡萄糖（FDG） PET/CT显像最大标准摄取值（SUVmax）与来自2家机构的下咽鳞状细胞癌患者长期随访后总生存率间可能存在的相关性，分析SUVmax与几个生存状态间的关系，包括无肺转移生存。方法81例患者的生存率用乘积极限法（Kaplan-Meier法）计算。单变量和多变量分析采用Cox比例风险模型进行。

关键词：下咽鳞状细胞癌 ^18F-FDG PET/CT SUVmax 总生存率肺转移

Development of osteomalacia in a post-liver transplant patient receiving adefovir dipivoxil

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World Journal of Hepatology 2010年第12期2卷 442-446页

作者： masami Minemura Yoshiharu Tokimitsu Kazuto Tajiri Yasuhiro Nakayama Kengo Kawai Hiroshi Kudo Katsuharu Hirano Yoshinari Atarashi Yutaka Yata Satoshi Yasumura Terumi Takahara Toshiro Sugiyama Third Department of Internal Medicine Faculty of MedicineUniversity of Toyama

We report the case of a patient treated with living donor-related liver transplantation who suffered from osteomalacia during adefovir dipivoxil (ADV)-containing antiviral therapy for lamivudine-resistant hepatitis B virus infection. The patient had generalized bone pain,with severe hypophosphatemia after 20 mo of ADV therapy. Radiographic studies demonstrated the presence of osteomalacia. The peak plasma ADV level was 38 ng/mL after administration of ADV at 10mg/day. It was also found that ADV affected the metabolism of tacrolimus,a calcineurin-inhibitor,and caused an increase in the plasma levels of tacrolimus. The disability was reversed with the withdrawal of ADV and with mineral supplementation. ADV can cause an elevation of plasma tacrolimus levels,which may be associated with renal dysfunction. High levels of ADV and tacrolimus can cause nephrotoxicity and osteomalacia. This case highlights the importance of considering a diagnosis of osteomalacia in liver transplantation recipients treated with both ADV and tacrolimus.

关键词： Hepatitis B virus Osteomalacia Adefovir dipivoxil Living donor-related liver transplantation Tacrolimus

Endoscopic lithotripsy with peroral direct cholangioscopy using a conventional endoscope

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World Journal of Gastrointestinal Endoscopy 2013年第3期5卷 132-134页

作者： So Nakaji Nobuto Hirata Toshiyasu Shiratori Masayoshi Kobayashi masami Inase Department of Gastroenterology Kameda Medical CenterKamogawa cityChiba 296-8602Japan

Recently,peroral direct cholangioscopy(PDCS) using an ultra-slim endoscope has come into the ***,the working channel is too small to use various devices for *** report a case of endoscopic lithotripsy with PDCS using a conventional endoscope as a *** tomography scan on an 80-year-old female who was admitted with acute cholangitis showed two large stones in the bile *** retrograde cholangiopancreatography was attempted ***,mechanical lithotripsy failed because the stone was too large for the basket ***,electric hydraulic lithotripsy with PDCS using a conventional endoscope was performed allowed the stones to be cleared *** conclusion,PDCS using a conventional endoscope can be an alternative solution for endoscopic lithotripsy for patients with large stones in the dilated bile duct.

关键词： Peroral direct cholangioscopy Electric hydraulic lithotripsy Conventional endoscope Bile duct stone Transpapillary lithotripsy

Proposition of a New Type of Jointless System For Existing Concrete Bridges

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Journal of Physical Science and Application 2014年第2期4卷 84-89页

作者： Yuichi Ishikawa Minobu Aoyama masami Kuroyanagi Masatugu Nagai Takeshi Miyashita Kanazawa Branch Central Nippon Highway Engineering Nagoya Co. Ltd. Kanazawa 920-0025 Japan Nagoya Branch Central Nippon Expressway Co. Ltd. Nagoya 460-0003 Japan Department of Civil and Environmental Engineering Nagaoka University of Technology Nagaoka 940-2188 Japan

The Association of Autism Spectrum Disorders and Symptoms of Asthma, Allergic Rhinoconjunctivitis and Eczema among Japanese Children Aged 3 - 6 Years

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Health 2017年第8期9卷 1235-1250页

作者： Daisuke Hori Hiromasa Tsujiguchi Yasuhiro Kambayashi Toshio Hamagishi masami Kitaoka Junko Mitoma Hiroki Asakura Fumihiko Suzuki Enoch Olando Anyenda Nguyen Thi Thu Thao Yohei Yamada Satoko Tamai Koichiro Hayashi Yuri Hibino Aki Shibata Takiko Sagara Shinichiro Sasahara Ichiyo Matsuzaki Hiroyuki Nakamura Department of Environmental and Preventive Medicine Graduate School of Medical Science Kanazawa University Kanazawa Japan Faculty of Medicine University of Tsukuba Tsukuba Japan International Institute for Integrative Sleep Medicine University of Tsukuba Tsukuba Japan

There is insufficient epidemiological evidence on the relationship between autism spectrum disorder (ASD) and allergic diseases. We performed a cross-sectional survey to elucidate the associations between them using validated screening tools. The participants were children aged 3 - 6 years attending kindergarten or nursery school in Shika Town, Japan (n = 417;valid response rate = 80.4%). Autism spectrum features were scored on the Social Communication Questionnaire (SCQ). Allergic symptoms (asthma, allergic rhinoconjunctivitis, and eczema) were determined according to the criteria of the International Study of Asthma and Allergies in Childhood. A total of 15 children (4.5%) had an SCQ score of 11 points or higher. The prevalence of symptoms was 14.7% for asthma, and 5.3% for allergic rhinoconjunctivitis, and 11.4% for eczema. Logistic regression indicated that symptoms of eczema were significantly associated with SCQ scores of 11 points or higher [odds ratio (OR), 4.38;95% confidence interval (CI), 1.41 - 13.59]. The association persisted after adjustment for age, sex, and BMI (OR, 3.84;95% CI, 1.20 - 12.24). Moreover, asthmatic symptoms were significantly associated with male sex (OR, 2.09;95% CI, 1.12 - 3.92) and overweight status (OR, 2.45;95% CI, 1.03 - 5.83). This suggests that higher SCQ scores, which imply more autism spectrum features, are associated with higher prevalence of eczema symptoms. While no causal relationships can be made, ASD might be associated with eczema.

关键词： Asthma Autism Spectrum Disorder Eczema Early Screening Social Communication Questionnaire

The Association between Activity of Daily Living and the Combination of Alzheimer’s Disease and Cataract in Elderly Requiring Nursing Care

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Health 2016年第10期8卷 994-1003页

作者： Toshio Hamagishi Toshimitsu Inagawa Yasuhiro Kambayashi Hiromasa Tsujiguchi masami Kitaoka Junko Mitoma Hiroki Asakura Fumihiko Suzuki Daisuke Hori Enoch Olando Anyenda Nguyen Thi Thu Thao Yuri Hibino Koichi Hayashi Aki Shibata Takiko Sagara Jiro Okochi Kiyoshi Takamoku Kotaro Hatta Tadashi Konoshita Hiroyuki Nakamura Department of Environmental and Preventive Medicine Graduate School of Medical Science Kanazawa University Ishikawa Japan Department of Food Sciences and Nutrition School of Human Environmental Sciences Mukogawa Women’s University Hyogo Japan Department of Lifestyle Studies Kobe Shoin Women’s University Hyogo Japan Department of Nutritional Sciences for Well-Being Kansai University of Welfare Sciences Osaka Japan Japan Association of Geriatric Health Service Facilities Tokyo Japan Department of Psychiatry Juntendo University Nerima Hospital Tokyo Japan Third Department of Internal Medicine Fukui University School of Medicine Fukui Japan

Some clinical and epidemiological studies have suggested that Alzheimer’s Disease (AD) and cataract, may share common pathogenetic mechanisms, subsequently a positive association between the prevalence of AD and cataract, although other studies found no significant relationship between dementia and visual impairment including cataract in the elderly. Little is known about the association between Activity of Daily Living (ADL) and the combination of AD and cataract. To examine the association between ADL and the combination of AD and cataract, we performed a national survey in nursing care institutions in Japan, examining the decreased ADL in elderly with and without AD and cataract for 453 elderly aged 85.0 ± 8.13 years. The proportion, 43.5% of AD in subjects without cataract was significantly higher than that, 23.5% with cataract. Almost all ADL in AD with cataract was significantly lower than that without cataract, although all ADL in cataract patients receiving surgery in AD was significantly (all p < 0.002) higher than that in cataract patients without surgery in AD, as was confirmed by the multiple regression analysis incorporating into the relevant factors as independent variables. These results showed that ADL scores including cognitive functions decreased by cataract were increased by the surgery in the patients with AD. A significantly negative association between AD and cataract seen in our data, which was inconsistent with the previous result, might lead to the necessities of the clinical diagnosis for slight severity of cataract for patients with AD.

关键词： Alzheimer’s Disease Cataract Elderly Activity of Daily Living Cognitive Function

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用电容器提高CPU电源的效率

电子设计技术 2002年第11期 81-81页

作者： masami Muranaka Maxim integrated products

对于为笔记本电脑提供大电流的DC/DC补偿变换器,高效率很重要的。高效率可延长电池寿命,降低温升。一种使用外接MOSFET的低功耗同步整流器,它的效率就很高。然而,在使用同步整流器时必须特别小心。如果设计不当,在高端MOSFET与低端MOSFE... 详细信息

对于为笔记本电脑提供大电流的DC/DC补偿变换器,高效率很重要的。高效率可延长电池寿命,降低温升。一种使用外接MOSFET的低功耗同步整流器,它的效率就很高。然而,在使用同步整流器时必须特别小心。如果设计不当,在高端MOSFET与低端MOSFET同时

关键词：电源 CPU 滞后时间迟延时间

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《白虎通》之“或曰”與“一説”

经学文献研究集刊 2019年第1期 121-134页

作者：〔日〕田中麻紗巳劉瑩(译) 石碱(校) 京都女子大學北京大學哲學系

本文主要分析了《白虎通》中四十余處引用'或曰''一説'的記述。後漢章帝時期,在白虎觀討論當時經學説的異同,對於多數争論裁定出的正確而妥當的解釋,都記録在了《白虎通》之中。其書的大部分只記載了定下來的解釋,只有約四十處的末尾以... 详细信息

本文主要分析了《白虎通》中四十余處引用'或曰''一説'的記述。後漢章帝時期,在白虎觀討論當時經學説的異同,對於多數争論裁定出的正確而妥當的解釋,都記録在了《白虎通》之中。其書的大部分只記載了定下來的解釋,只有約四十處的末尾以'或曰'還有'一説'爲始附上了别的解釋。其中正確而妥當的解釋稱之爲主説,'或曰''一説'以下稱爲别説。通過分析,可以把别説分爲補充主説,提示異説,還有反對主説三類。參照諸例,提示異説的情況最多,反對主説的用例最少。在與經學説的關係中,補充主説的别説,即便有不同于《春秋》説和《禮》説等之處,主説與别説也都屬於今文學派之説。提示異説的用例雖然也幾乎同樣如此,但有少數的别説是與古文説同説的今文説。在反對主説的用例中,果然有主説和别説都是今文説之例,别的情況有主説是與古文説相似的今文説,而别説是今文學派的他説之例,還有主説是今文説而别説是古文説之例。雖然是極少數,但是確有認可古文説的情況。當時的朝廷被今文學派的博士官獨佔,參加白虎觀論議的也都是今文經學的習得者。只是,參加的賈逵是兼修今文學的古文學派,而丁鴻是兼修古文學的今文學派。也許正因爲他們的支持,少量的古文學説才得以存在。稍後賈逵的弟子許慎著《五經異議》,就是從古文學派的立場討論經學説。重視今古文學的框架的大勢已然存續,只是不拘泥于這種傾向的萌芽在白虎觀論議中應該也是可以見出的。

关键词：補充·異說·反对多數說與少數說今古文的兼修