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Randomized controlled trial of pancreatic stenting to prevent pancreatitis after endoscopic retrograde cholangiopancreatography

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World Journal of Gastroenterology 2012年第14期18卷 1635-1641页

作者： Yoshiaki Kawaguchi masami ogawa Fumio Omata Hiroyuki Ito Tooru Shimosegawa Tetsuya Mine Division of Gastroenterology Tokai University School of MedicineIsehara 259-1193Japan Division of Gastroenterology Tohoku University Graduate School of Medicine1-1 Seiryo-machiAobakuSendai CityMiyagi 980-8574Japan

AIM:To determine the effectiveness of pancreatic duct(PD) stent placement for the prevention of pancreatitis after endoscopic retrograde cholangiopancreatography(ERCP) in high risk ***:Authors conducted a single-blind,randomized controlled trial to evaluate the effectiveness of a pancreatic spontaneous dislodgement stent against post-ERCP pancreatitis,including rates of spontaneous dislodgement and *** defined high risk patients as having any of the following:sphincter of Oddi dysfunction,difficult cannulation,prior history of post-ERCP pancreatitis,pre-cut sphincterotomy,pancreatic ductal biopsy,pancreatic sphincterotomy,intraductal ultrasonography,or a procedure time of more than 30 *** were randomized to a stent group(n = 60) or to a non-stent group(n = 60).An abdominal radiograph was obtained daily to assessspontaneous stent ***-ERCP pancreatitis was diagnosed according to consensus ***:The mean age(± standard deviation) was 67.4 ± 13.8 years and the male:female ratio was 68:*** the stent group,the mean age was 66 ± 13 years and the male:female ratio was 33:27,and in the non-stent group,the mean age was 68 ± 14 years and the male:female ratio was 35:*** were no significant differences between groups with respect to age,gender,final diagnosis,or type of endoscopic *** frequency of post-ERCP pancreatitis in PD stent and non-stent groups was 1.7%(1/60) and 13.3%(8/60),*** severity of pancreatitis was mild in all *** frequency of post-ERCP pancreatitis in the stent group was significantly lower than in the non-stent group(P = 0.032,Fisher's exact test).The rate of hyperamylasemia were 30%(18/60) and 38.3%(23 of 60) in the stent and non-stent groups,respectively(P = 0.05,χ2 test).The placement of a PD stent was successful in all 60 *** rate of spontaneous dislodgement by the third day was 96.7%(58/60),and the median(range) time to dislodgement was 2.1(2-

关键词：随机对照试验胰腺癌胰腺炎胆管内镜预防支架

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Small serotonin-positive pancreatic endocrine tumors caused obstruction of the main pancreatic duct

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World Journal of Gastroenterology 2012年第45期18卷 6669-6673页

作者： masami ogawa Yoshiaki Kawaguchi Atsuko Maruno Hiroyuki Ito Toshio Nakagohri Kenichi Hirabayashi Hiroshi Yamamuro Tomohiro Yamashita Tetsuya Mine Department of Gastroenterology Tokai University School of Medicine143 ShimokasuyaIsehara 259-1193Japan Department of Gastroenterological Surgery Tokai University School of Medicine143 ShimokasuyaIsehara 259-1193Japan Department of Pathology Tokai University School of Medicine143 ShimokasuyaIsehara 259-1193Japan Department of Radiology Tokai University School of Medicine143 ShimokasuyaIsehara 259-1193Japan

We report 2 cases of pancreatic endocrine tumors that caused obstruction of the main pancreatic duct(MPD).A 49-year-old asymptomatic man was referred to our institution because dilation of the MPD was revealed by abdominal ultrasonography(US).No tumor was detected by endoscopic ultrasonography,computed tomography(CT),and magnetic resonance imaging(MRI).The diameter of the MPD was > 20 mm at the body,and no dilation was noted at the *** malignancy was not confirmed through cytology or imaging,pancreatic cancer was strongly ***-denectomy was *** and immunohistochemical examination revealed a 5 mm × 3 mm serotonin-positive endocrine *** was present around the MPD and seemed to cause stricture.A 32-year-old asymptomatic man had elevated serum amylase,and US demonstrated dilation of the *** tumor was detected by CT and *** cancer was suspected due to stricture and dilation of the *** of middle part of pancreas was *** and immunohistochemical examination revealed a serotonin-positive endocrine tumor sized 5 mm × 4 *** report 2 cases of serotonin-positive pancreatic endocrine tumors that caused stricture of the MPD in spite of the small size of the tumor.

关键词：恶性肿瘤胰腺癌内分泌羟色胺阳性胰管病理组织学梗阻

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Daytime-nighttime variations in the concentration of PM_(0.1) carbonaceous particles during a biomass fire episode in Chiang Mai,Thailand

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Particuology 2024年第4期87卷 316-324页

作者： Worradorn Phairuang Thaneeya Chetiyanukornkul Phuchiwan Suriyawong Sotasing Ho Phakphum Paluang masami Furuuchi Muhammand Amin Mitsuhiko Hata Faculty of Gesciences and CivilEngineering Institute of Science and Enginering Kanazawa UniverityKanazawaIshkawa92192Japan Department of Geography Faculty of Social SciencesChiang Mai UniversityMuangChiang Mai 50200Thailand Department of Biology Faculty of ScienceChiang Mai UniversityMuangChiang Mai50200Thailand Research Unit for Eergyonomics and Eological Management Multidisciplinary Research Insttute Chiang Mai UniversityChiang Mai50200Thailand Management and Development Training Program Office National Institute of ScienceTechnology and Innovation120601Cambodia Faculty of Engineering Maritim University of Raja Ali HajTanjung PinangKepulauan Riau29115Indonesia

Carbonaceous aerosols affect air quality adversely,affect global warming,and human ***,our understanding of the impact of ultrafine(PM_(0.1))carbonaceous particulate matter is incomplete,particularly the effects during haze *** study monitored diurnal variations in PM_(0.1) in Chiang Mai,Thailand,from March to April *** investigated carbonaceous PM_(0.1) collected by an ambient nano-sampler and evaluated their effect by using a carbon analyzer(IMPROVE_TOR).The results showed that burning large open areas in the dry season was crucial for increasing the particle mass concentration because of the large open burnings that occurred in this *** majority of biomass fires near the sampling site occurred during the night,which would allow more particles to be released thus resulting in higher concentrations of PM_(0.1).Hence,the release of PM_(0.1) during the night would obviously result in higher concentrations than that during the *** the eight carbon profiles,organic carbon 3(OC3)was predicted to be a marker of biomass *** carbon indices displayed that PM_(0.1) was influenced by biomass burning both daytime and *** findings reported herein should be of great impor-tance in terms of establishing biomass burning control policies for mitigating heavy haze pollution in Thailand and elsewhere.

关键词： Biomass burning Carbon Forest fires Nanoparticles Ultrafine particles

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Amenorrhea as a rare drug-related adverse event associated with everolimus for pancreatic neuroendocrine tumors

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World Journal of Gastroenterology 2014年第42期20卷 15920-15924页

作者： Yoshiaki Kawaguchi Atsuko Maruno Yohei Kawashima Hiroyuki Ito masami ogawa Tetsuya Mine Department of Gastroenterology Tokai University School of Medicine

The patient was an asymptomatic 43-year-old woman. Abdominal ultrasonography and enhanced computed tomography showed a tumor lesion accompanied by multiple cystic changes in the liver and the pancreatic tail. Endoscopic ultrasound-fine needle aspiration was performed on the pancreatic tumor lesion and revealed pancreatic neuroendocrine tumor(PNET). As it was unresectable due to multiple liver metastases, the decision was made to initiate treatment with everolimus and transcatheter arterial chemoembolization. The patient ceased menstruating after the start of everolimus administration. When the administration was discontinued due to interstitial lung disease, menstruation resumed, but then again stopped with everolimus resumption. An association between everolimus and amenorrhea was highly suspected. Amenorrhea occurred as a rare adverse event of everolimus. As the younger women might be included in PNETs patients, we should put this adverse event into consideration.

关键词： Amenorrhea Everolimus Neuroendocrine tumor Pancrea

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Size-fractionated carbonaceous particles and climate effects in the eastern region of Myanmar

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Particuology 2024年第7期90卷 31-40页

作者： Mai Kai Suan Tial Nwe Nwe Kyi Muhammad Amin Mitsuhiko Hata masami Furuuchi Rahmi Mulia Putri Phakphum Paluang Phuchiwan Suriyawong Worradorn Phairuang Department of Electrical Power Engineering Yangon Technological UniversityYangon11011Myanmar Faculty of Geosciences and Civil Engineering Institute of Science and EngineeringKanazawa UniversityKanazawaIshikawa920-1192Japan Faculty of Engineering Maritim University of Raja Ali HajiTanjung PinangKepulauan Riau 29115Indonesia Graduate School of Natural Science and Technology Kanazawa UniversityKanazawaIshikawa920-1192Japan Department of Geography Faculty of Social SciencesChiang Mai UniversityMuangChiang Mai50200Thailand Research Unit for Energy Economics and Ecological Management Multidisciplinary Research InstituteChiang Mai UniversityMuangChiang Mai50200Thailand

This study reports on an investigation of fine and coarse carbonaceous particulate matters(PM)in Tachileik,eastern Myanmar,during the dry and wet seasons of *** carbon compositions,including organic carbon(OC)and elemental carbon(EC),in each size(PM10-2.5,PM2.5-1.0,and PM1.0-0.5)were determined by a carbon *** average total mass concentration of the three fractions of particle samples during the dry season was higher(51.23±23.86μg/m3)than that of the wet season(14.00±5.26μg/m3).The results indicate that OC and EC levels were highest for PM1.0-0.5 during the dry season and the sizes were similar for both *** OC/EC ratios varied in different seasons,from 1.93 to 4.40 and 4.13 to 5.25 in the dry and wet seasons,*** was sub-divided into char-EC and soot-EC;the char-EC/soot-EC in the dry season was higher than in the wet season,signifying that biomass burning is the main particle source during the dry ***,vehicle emissions dominated during the wet *** effective carbon ratio(ECR)suggested that finer particles contributed more to global *** information is important in terms of air quality control and mitigation in Myanmar and elsewhere.

关键词： Air quality Biomass burning Carbon Coarse particles Fine particles Myanmar

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Risk factors for proximal migration of biliary tube stents

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World Journal of Gastroenterology 2014年第5期20卷 1318-1324页

作者： Yoshiaki Kawaguchi masami ogawa Yohei Kawashima Hajime Mizukami Atsuko Maruno Hiroyuki Ito Tetsuya Mine Department of Gastroenterology Tokai University School of Medicine

AIM: To analyze the risk factors for biliary stent migration in patients with benign and malignant strictures. METHODS: Endoscopic stent placement was performed in 396 patients with bile duct stenosis, at our institution, between June 2003 and March 2009. The indications for bile duct stent implantation included common bile duct stone in 190 patients, malignant lesions in 112, chronic pancreatitis in 62, autoimmune pancreatitis in 14, trauma in eight, surgical complications in six, and primary sclerosing cholangitis(PSC) in four. We retrospectively examined the frequency of stent migration, and analyzed the patient factors(disease, whether endoscopic sphincterotomy was performed, location of bile duct stenosis and diameter of the bile duct) and stent characteristics(duration of stent placement, stent type, diameter and length). Moreover, we investigated retrieval methods for migrated stents and their associated success rates. RESULTS: The frequency of tube stent migration inthe total patient population was 3.5%. The cases in which tube stent migration occurred included those with common bile duct stones(3/190; 1.6%), malignant lesions(2/112; 1.8%), chronic pancreatitis(4/62; 6.5%), autoimmune pancreatitis(2/14; 14.3%), trauma(1/8; 12.5%), surgical complications(2/6; 33.3%), and PSC(0/4; 0%). The potential risk factors for migration included bile duct stenosis secondary to benign disease such as chronic pancreatitis and autoimmune pancreatitis(P = 0.030); stenosis of the lower bile duct(P = 0.031); bile duct diameter > 10 mm(P = 0.023); duration of stent placement > 1 mo(P = 0.007); use of straight-type stents(P < 0.001); and 10-Fr sized stents(P < 0.001). Retrieval of the migrated stents was successful in all cases. The grasping technique, using a basket or snare, was effective for pig-tailed or thin and straight stents, whereas the guidewire cannulation technique was effective for thick and straight stents. CONCLUSION: Migration of tube stents within the bile duct

关键词： Migration Endoscopic biliary stent Risk factor End

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Synchronous pancreatic solid pseudopapillary neoplasm and intraductal papillary mucinous neoplasm

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World Journal of Gastroenterology 2013年第21期19卷 3358-3363页

作者： Kenichi Hirabayashi Giuseppe Zamboni Hiroyuki Ito masami ogawa Yoshiaki Kawaguchi Tomohiro Yamashita Toshio Nakagohri Naoya Nakamura Department of Pathology Tokai University School of MedicineIsehara 259-1193Japan Department of Pathology Ospedale Sacro Cuore Don Calabria37024 Negrar VeronaItaly Department of Pathology University of Verona37134 Negrar VeronaItaly Department of Gastroenterology Tokai University School of MedicineIsehara 259-1193Japan Department of Radiology Tokai University School of MedicineIsehara 259-1193Japan Department of Gastroenterological Surgery Tokai University School of MedicineIsehara 259-1193Japan

Solid pseudopapillary neoplasm (SPN) is a rare and low-grade malignant pancreatic neoplasm composed of poorly cohesive monomorphic neoplastic cells forming solid and pseudopapillary structures with frequent hemorrhagic-cystic degeneration. Intraductal papillary mucinous neoplasm (IPMN) is a pancreatic exocrine tumor composed of intraductal papillary growth of mucin containing neoplastic cells in the main pancreatic duct or its major branches. In the case presented here, a 53-year-old, Japanese man was found to have multiple cystic lesions and dilatation of the main pancreatic duct in the neck of the pancreas. Histological examination revealed a main-duct and branch-duct type IPMN, of the gastric-type, involving the neck of the pancreas, associated with a 0.5 cm SPN in the caudal side of the IPMN. We diagnosed this case as synchronous SPN and IPMN. As far as we know, only one other case of synchronous SPN and IPMN has been reported. Both the present case and the previously reported case showed abnormal nuclear expression of β-catenin in SPN, whereas IPMN showed no abnormal nuclear expression. These results suggest that β-catenin abnormality is not a common pathogenetic factor of synchronous SPN and IPMN.

关键词： Intraductal papillary mucinous neoplasms Solid pseudopapillary neoplasms Pancreatic neoplasms Synchronous neoplasms Pancreas Beta-catenin

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Subloading-friction model with saturation of tangential contact stress

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Friction 2023年第6期11卷 1107-1120页

作者： Koichi HASHIGUCHI masami UENO Kyushu University Fukuoka 819-0395Japan MSC Software Ltd. Tokyo 101-0054Japan University of the Ryukyus Okinawa 903-0213Japan

The incorporation of the saturation of the tangential contact stress with the increase of the normal contact stress is required for the analysis of the friction phenomenon of solids and structures subjected to a high normal contact stress,which cannot be described by the Coulomb friction condition,in which the tangential contact stress increases linearly with the increase of the normal contact *** this article,the subloading-friction model,which is capable of describing the smooth elastic-plastic transition,the static-kinetic transition,and the recovery of the static friction during the cease of sliding,is extended to describe this ***,some numerical examples are shown,and the validity of the present model will be verified by the simulation of the test data on the linear sliding of metals.

关键词： high contact stress monotonic/reciprocal sliding static/kinetic friction subloading-friction model

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Description of sand–metal friction behavior based on subloadingfriction model

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Friction 2022年第10期10卷 1660-1675页

作者： Toshiyuki OZAKI Yuki YAMAKAWA masami UENO Koichi HASHIGUCHI Kyushu Electric Engineering Consultants Inc. Fukuoka 810-0005Japan Department of Civil and Environmental Engineering Tohoku UniversitySendai 980-8579Japan University of the Ryukyus Okinawa 903-0213Japan MSC Software Ltd. Tokyo 101-0054Japan Kyushu University Fukuoka 819-0395Japan

A subloading-friction model is formulated to describe the smooth transient variation from static friction to kinetic friction,the recovery to static friction after the sliding velocity decreases,and the accumulation of sliding displacement under the cyclic loading of contact *** the past relevant studies,however,the model formulation used for simulations is limited to the hypoelastic-based plasticity framework,and the validation of the model is limited to simulations of the test data for metal-to-metal *** this study,the formulation of the subloading-friction model based on a hyperelastic-based plasticity framework is *** the fields of civil,geotechnical,agricultural engineering,and terramechanics,the interaction between soils and metals is critical,as reflected in construction and agricultural machinery,foundation piles,and retaining *** validity of the model for describing the friction between various sands and metals is verified by simulations of the experimental data under monotonic and cyclic loadings.

关键词： subloading-friction model sand-metal friction monotonic/cyclic sliding static/kinetic friction

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Analysis of the Relationship between Eating and Swallowing Function and Lifestyle of the Elderly Living in the Community-A Secondary Publication

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Journal of Clinical and Nursing Research 2024年第2期8卷 56-69页

作者： Naito Tomoyoshi Yamada masami Nakamura Mi Eiko Ojima Toshiyuki Hamamatsu Medical University Shizuoka 431-3125HamamatsuJapan Department of Nursing Faculty of Medical SciencesTeikyo University of Science and TechnologyTokyo 120-0045Japan Hamamatsu Medical University Department of Health and Social MedicineShizuoka 431-3125HamamatsuJapan

Objectives:The relationship between eating and swallowing function,and lifestyle among community-dwelling elderly people has not been extensively *** study aimed to analyze the characteristics of eating and swallowing function and their association with the lifestyle among the ***:A self-administered questionnaire survey was conducted on 419 elderly people who participated in the oral function improvement project operated by the Community Comprehensive Support Center.A total of 288 valid responses(58 males,230 females,average age 73.6 years)were *** survey items included basic demographics,health status,lifestyle,and eating and swallowing *** chi-square(χ2)test was used to compare for a difference in the risk of ***:72 patients(25.0%)were judged to be at risk for dysphagia,and 216(75.0%)were judged to be not at risk for dysphagia using the revised dysphagia risk assessment *** mean score for oral preparatory dysphagia was the highest,while the mean score for pharyngeal dysphagia was the *** group at risk of dysphagia had significant difficulty in chewing and had bad sleep quality as compared to the group that was not at ***:Concerning the risk of dysphagia,there is a need to maintain and improve masticatory *** addition,improving the swallowing function of the elderly may prevent insomnia and improve sleep quality.

关键词： Elderly living in the community Eating and swallowing function Lifestyle

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