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Propensity score analysis demonstrated the prognostic advantage of anatomical liver resection in hepatocellular carcinoma

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World Journal of Gastroenterology 2014年第12期20卷 3335-3342页

作者： Masayuki Ishii Toru Mizuguchi masaki kawamoto Makoto Meguro Shigenori Ota Toshihiko Nishidate Kenji Okita Yasutohsi Kimura Thomas T Hui Koichi Hirata Department of Surgery Surgical Oncology and ScienceSapporo Medical University Hospital Sapporo Medical University Department of Surgery Children’s Hospital and Research Center Oakland

AIM: To compare the prognoses of hepatocellular carcinoma (HCC) patients that underwent anatomic liver resection (AR) or non-anatomic liver resection (NAR) using propensity score-matched populations.

关键词： Anatomical liver resection Propensity score analysis Hepatocellular carcinoma

Current standard values of health utility scores for evaluating costeffectiveness in liver disease:A meta-analysis

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World Journal of Gastroenterology 2022年第31期28卷 4442-4455页

作者： Tomohiro Ishinuki Shigenori Ota Kohei Harada masaki kawamoto Makoto Meguro Goro Kutomi Hiroomi Tatsumi Keisuke Harada Koji Miyanishi Toru Kato Toshio Ohyanagi Thomas T Hui Toru Mizuguchi Department of Nursing Surgical SciencesSapporo Medical UniversitySapporo 0608556Japan Departments of Surgery Surgical Science and OncologySapporo Medical UniversitySapporo 0608543Japan Department of Radiology Sapporo Medical UniversitySapporo 0608543Japan Departments of Surgery Nemuro City HospitalNemuro 0870008Japan Departments of Surgery Sapporo Satozuka HospitalSapporo 0040811Japan Department of Intensive Care Medicine Sapporo Medical UniversitySapporo 0608543Japan Department of Emergency Medicine Sapporo Medical UniversitySapporo 0608543Japan Department of Medical Oncology Sapporo Medical UniversitySapporo 0608543Japan Department of Liberal Arts and Sciences Center for Medical EducationSapporo Medical UniversitySapporo 0608556Japan Departments of Surgery Stanford University School of MedicineStanford94598United States

BACKGROUND Health utility assessments have been developed for various conditions,including chronic liver *** utility scores are required for socio-economic evaluations,which can aid the distribution of national ***,the standard health utility assessment scores for specific health conditions are largely *** To summarize the health utility scores,including the EuroQOL 5-dimensions 5-levels(EQ-5D-5L),EuroQol-visual analogue scale,short from-36(SF-36),RAND-36,and Health Utilities Index(HUI)-Mark2/Mark3 scores,for the normal population and chronic liver disease *** A systematic literature search of PubMed and MEDLINE,including the Cochrane Library,was ***-analysis was performed using the RevMan *** means and standard deviations were combined using the StatsToDo online web *** The EQ-5D-5L and SF-36 can be used for health utility evaluations during antiviral therapy for hepatitis ***-Mark2/Mark3 indicated that the health utility scores of hepatitis B patients are roughly 30% better than those of hepatitis C *** The EQ-5D-5L is the most popular questionnaire for health utility *** assessments that allow free registration would be useful for evaluating health utility in patients with liver disease.

关键词： Quality of life EuroQOL 5-dimensions 5-levels Short from-36 RAND-36 Health Utilities Index-Mark

Assessment of liver fibrosis by a noninvasive method of transient elastography and biochemical markers

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World Journal of Gastroenterology 2006年第27期12卷 4325-4330页

作者： masaki kawamoto Toru Mizuguchi Tadashi Katsuramaki Minoru Nagayama Hideki Oshima Hiroyuki Kawasaki Takayuki Nobuoka Yasutoshi Kimura Koichi Hirata Department of Surgery Ⅰ Sapporo Medical University HospitalSapporo Medical University School of MedicineS-1W-16Chuo-KuSapporoHokkaido 060-8543Japan

AIM： To assess the correlation between the fibrotic area （FA） as calculated by a digital image analysis （DIA）, and to compare the diagnostic accuracy of FibroScan to the other existing Liver fibrosis （LF） markers using the receiver operating curve analysis.METHODS： We recruited 30 patients who underwent a liver resection for three different etiologies including normal liver, hepatitis B, and hepatitis C. Liver stiffness was measured by using a FibroScan. The FA was then calculated by DIA to evaluate LF in order to avoid any sampling bias. RESULTS： The FA negatively correlated with Prothrombin time （PT）, platelet count, lecithin-cholesterol acyltransferase （LCAT）, and pre-albumin （ALB）. On the other hand, the findings of FibroScan correlated with similar markers. The FA positively correlated with FibroScan, serum hyaluronate level, and type Ⅳ collagen level, and aspartate transaminase to platelet ratio index （APRI）. The area under the receiver operating curve for FibroScan was higher than that for the other markers, even though the statistical significance was minimal. CONCLUSION： Our findings suggest that FibroScan can initially be used to assess LF as an alternative to a liver biopsy （LB） and serum diagnosis, because it is a safe method with comparable diagnostic accuracy regarding the existing LF markers.

关键词： Cirrhosis Digital image analysis Fibro-Scan Fibrotic area Hyaluronate Lecithin-cholesterol acyltransferase Liver fibrosis Pre-albumin

Maturation of robotic liver resection during the last decade:A systematic review and meta-analysis

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World Journal of Meta-Analysis 2021年第5期9卷 462-473页

作者： Tomohiro Ishinuki Shigenori Ota Kohei Harada Makoto Meguro masaki kawamoto Goro Kutomi Hiroomi Tatsumi Keisuke Harada Koji Miyanishi Ichiro Takemasa Toshio Ohyanagi Thomas T Hui Toru Mizuguchi Department of Nursing Surgical SciencesSapporo Medical UniversitySapporo 0608556HokkaidoJapan Departments of Surgery Surgical Science and OncologySapporo Medical UniversitySapporo 0608543HokkaidoJapan Division of Radiology Sapporo Medical UniversitySapporo 060-8543HokkaidoJapan Departments of Surgery Sapporo Satozuka HospitalSapporo 0048686Japan Departments of Surgery Nemuro City HospitalNemuro 0878686HokkaidoJapan Department of Surgery School of MedicineSapporo Medical UniversitySapporo 0608543HokkaidoJapan Department of Intensive Care Medicine Sapporo Medical University HospitalSapporo 0608543HokkaidoJapan Department of Emergency Medicine Sapporo Medical UniversitySapporo 0606543HokkaidoJapan Department of Medical Oncology Sapporo Medical UniversitySapporo 0608543HokkaidoJapan Department of Liberal Arts and Sciences Center for Medical EducationSapporo Medical UniversitySapporo 0608556HokkaidoJapan Department of Surgery Division of Pediatric SurgeryStanford University School of MedicineStanfordCA 94598United States

BACKGROUND Minimally invasive hepatectomy techniques have developed rapidly since *** laparoscopic liver resection(LLR)has become the primary approach for managing liver tumors and procuring donor organs for liver *** liver resection(RLR)has emerged during the last *** technical status of RLR seems to be *** To conduct a systematic review and meta-analysis comparing the short-term clinical outcomes of LLR and RLR over two 5-year *** A systematic literature search was performed using PubMed and Medline,including the Cochrane *** following inclusion criteria were set for the meta-analysis:(1)Studies comparing LLR vs RLR;and(2)Studies that described clinical outcomes,such as the operative time,intraoperative bleeding,intraoperative conversion rate,and postoperative *** A total of 25 articles were included in this meta-analysis after 40 articles had been subjected to full-text *** studies were divided into early(n=14)and recent(n=11)*** the recent group,the operative time did not differ significantly between LLR and RLR(P=0.70),whereas in the early group the operative time of LLR was significantly shorter than that of RLR(P<0.001).CONCLUSION The initial disadvantages of RLR,such as its long operation time,have been overcome during the last 5 *** other clinical outcomes of RLR are comparable to those of *** cost and quality-of-life outcomes of RLR should be evaluated in future studies to promote its routine clinical use.

关键词： Hepatectomy Laparoscopy Robot Operation time

Recent Development of Steelmaking Process in Sumitomo Metals

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Journal of Iron and Steel Research International 2011年第S2期18卷 28-35页

作者： Masayuki kawamoto Sumitomo Metal Industries Ltd.1-8-11 Harumi Chuo-ku Tokyo 104-6111Japan

Sumitomo Metal *** the third place steelmaking company for productivity in ***,we have some first Japanese innovations results in steelmaking *** this report,SRP process and some topics for continuous casting have bee... 详细信息

关键词： SRP SSC PCCS AI nozzle continuous casting steelmaking

Aggregation-induced emission and thermally activated delayed fluorescence of 2,6-diaminobenzophenones

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Science China Chemistry 2018年第8期61卷 925-931页

作者： masaki Shimizu masaki Nakatani Kenta Nishimura Faculty of Molecular Chemistry and Engineering Kyoto Institute of Technology

Exploration of novel organic luminophores that exhibit thermally activated delayed fluorescence(TADF) in the aggregated state is very crucial for advance of delayed luminescence-based applications such as time-gated bio-sensing and temperature *** report herein that synthesis, photophysical properties, molecular and crystal structures, and theoretical calculations of 2,6-bis(diarylamino)benzophenones. Absorption spectra in solution and calculations using density functional theory(DFT) method revealed that the optical excitation took place through intramolecular charge-transfer from one diarylamino moiety to an aroyl group. While the benzophenones did not luminesce in solution, the solids of the benzophenones emitted green light with moderate-to-good quantum yields. Thus, the benzophenones exhibit aggregation-induced emission. Based on the lifetime measurement, the green emission of the solids was found to include TADF. The emergence of the TADF is supported by the small energy gap between the excited singlet and triplet states, which was estimated by time-dependent DFT calculations. Thin films of poly(methyl methacrylate) doped by the benzophenones also showed green prompt and delayed fluorescence whose lifetimes were in the order of microseconds. Linear correlation between logarithm value of TADF lifetime and temperature was observed with the benzophenone in powder, suggesting that the benzophenones can serve as molecular thermometers workable under aqueous conditions.

关键词： donor-acceptor system delayed fluorescence temperature sensor

Resourceability on nuclear fuel cycle by transmutation approach

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Science China Chemistry 2012年第9期55卷 1746-1751页

作者： OZAWA masaki SAITO masaki Research Laboratory for Nuclear Reactors Tokyo Institute of Technology2-12-1-N1-1 OokayamaMeguro-kuTokyo 152-8550Japan

A resourceability on nuclear fuel cycle by transmutation of fission products in the spent fuel of nuclear reactors is discussed in this paper to investigate the feasibility of ＂creation and utilization＂ of Apr6s ORIENT from Adv.-ORIENT cycle, in which chemical ＂separation and utilization＂ of nuclear rare metals （platinum group metals, Mo, Tc, rare earth, etc.） has been proposed since FY2006. Apr6s ORIENT research program was newly initiated in FY2011 for nuclear transmutation of fission products into stable or short-lived highly-valuable elements. In the resourceability of rare earth metals from fission products, non-radioactive Nd and Dy can be created from Pr and Tb, respectively, by transmutation. Especially, the Dy creation has relatively high feasibility of about 10-20 %/y in creation rate. A proper moderation of neutrons in blanket of fast reactors may be required to provide a high creation rate of La from Ba. In light platinum group metals, non-radioactive Ru can be created from Tc by transmutation, of which creation rate is about 4-5 %/y in blanket of fast reactors. Pd created from Rh is almost non-radioactively depending on the isotope fraction of 107pd. Rh creation from Ru is not feasible under the neutron irradiation of typical nuclear reactors.

关键词： Apres ORIENT Advanced ORIENT cycle nuclear rare metal transmutation nuclear fuel cycle

Depolymerization of polyamide 6 in hydrophilic ionic liquids

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Green Energy & Environment 2019年第2期4卷 166-170页

作者： Akio Kamimura Yuto Shiramatsu Takuji kawamoto Department of Applied Chemistry Yamaguchi University

Polyamide 6 underwent an efficient depolymerization in hydrophilic ionic liquids under microwave irradiation at 300C. The depolymerization completed within 60 min. Caprolactam was readily separated by simple extraction procedure and the ionic liquids were recovered and reused for several times. Addition of catalytic amounts of DMAP(N,N-dimethylaminopyridine) promoted the depolymerization *** present improved procedure provides a method to avoid direct distillation procedure, which consumes energy for the separation of caprolactam from ionic liquids. Although some contamination of ionic liquids was observed, the present procedure provides a new possibility for the use of ionic liquids for plastic chemical recycling from the viewpoint of development of an energy-saving methodology. Use of solubility switchable ionic liquids is also examined to explore a possibility for better separation although depolymerization did not work well.

关键词： Chemical recycling Polyamides Chemical conversion Ionic liquids

Communication Scheduling with Diversity for Unmanned Aircraft Systems Using Local 5G

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Journal of Communications and Information Networks 2020年第1期5卷 50-61页

作者： Takeru Kitagawa Yuichi kawamoto Nei Kato Graduate School of Information Sciences Tohoku University Aramaki-Aoba 6-3-09Aoba-kuSendai980-8579Japan

The use of unmanned aircraft systems(UAS)for critical public service missions by public organizations,local governments,and social users is *** radio transmission by unmanned aerial vehicles(UAVs)is indispensable in these *** of the standards suitable for UAV wireless communications is local ***,to introduce local 5G into a UAS,several problems specific to UASes must be *** include the deterioration of the signal-to-noise ratio due to topography and obstacles,the uncertainty of the communication environment due to the movement of multiple UAVs,and the limitation of the frequency *** address these problems and to introduce local 5G into the UAS,we propose a novel communication scheduling *** method incorporates transmission modes with *** evaluations shows that total data volumes increase by 1.9~3 times with the proposed scheduling method compared with transmission without diversity or efficient scheduling.

关键词： unmanned aircraft system(UAS) unmanned aerial vehicle(UAV) local 5G diversity scheduling LTE sidelink time division multiple access(TDMA)