检索结果-南通市图书馆

Manipulation of Micro Solid Particles and Induced Flows in Water by Laser Irradiation

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2007年第2期16卷 176-180页

作者： masahiro ota Hiroshi OKANO Makoto YOSHIDA Division of Mechanical Engineering Tokyo Metropolitan University1Minami-osawaHachi-ojiTokyo 192-0397Japan

Q-switch for pulsing laser beam and Galvano scanner for rapid scanning laser beam were adapted to manipulate micro solid particles in a water droplet. The trapping of fine particles at micron-sized diameters by a YAG laser system, induced flows, and the induced motion of the particles by laser beam irradiations are discussed. Particle rotations are observed by using anisotropic micro objects, and moreover the rotational rate with clockwise direction is 22 r/min. The fragments of a cover glass were mixed in a water droplet, and their size and shape are uneven. The rotation of that non-spheres without scanning by the Galvano scanner is also observed in water.

关键词： Laser trapping non-sphere particle optical radiation pressure laser scanning laser drive rotation

Involvement of Siglec-15 in regulating RAP1/RAC signaling in cytoskeletal remodeling in osteoclasts mediated by macrophage colony-stimulating factor

在线全文

学校读者我要写书评

暂无评论

Bone Research 2024年第3期12卷 571-581页

作者： Hideyuki Kobayashi M.Alaa Terkawi masahiro ota Tomoka Hasegawa Tomomaya Yamamoto Tomohiro Shimizu Dai Sato Ryo Fujita Toshifumi Murakami Norio Amizuka Norimasa Iwasaki Masahiko Takahata Department of Orthopaedic Surgery Faculty of Medicine and Graduate School of MedicineHokkaido UniversitySapporo 060-8638Japan Department of Developmental Biology of Hard Tissue Graduate School of Dental MedicineHokkaido UniversitySapporoJapan Department of Orthopaedic Surgery Dokkyo Medical UniversityMibu Shimotsuga 321-0293Japan

DNAX-associated protein 12 kD size(DAP12)is a dominant immunoreceptor tyrosine-based activation motif(ITAM)-signaling adaptor that activates costimulatory signals essential for *** several DAP12-associated receptors(DARs)have been identified in osteoclasts,including triggering receptor expressed on myeloid cells 2(TREM-2),C-type lectin member 5 A(CLEC5A),and sialic acid-binding Ig-like lectin(Siglec)-15,their precise role in the development of osteoclasts and bone remodeling remain poorly *** this study,mice deficient in Trem-2,Clec5a,Siglec-15 were generated.

关键词： remodeling osteoclast stimulating

DEVELOPMENT OF DIRECT UPGRADING PROCESS FOR HEAVY CRUDE OIL

在线全文

学校读者我要写书评

暂无评论

石油学报（石油加工） 2001年第1期17卷 101-106页

作者： masahiro YOSHIDA Nobuyuki ota Technical cooperation project research & development dept. Idemitsu kosan Co LTD 24-4 Anesaki-Kaigan Ichihara，Chiba 299-0107Japan Central research lab. Idemitsum kosan Co LTD1280Kaini-Izumi Sodegaura-City Chiba 299-0293Japan

The direct upgrading process from heavy crude oil to sweet and light oil (IKC process) has been deve loped for about 10 years in Idemitsu Kosan. Compared with conventional refinery scheme consisting of YR HDS, VGOHYC and so on, the new refinery scheme combined with IKC process and Topper was always economically feasible with lower cost and smaller energy consumption. In the existing refinery of no middle distillate HDS and residue HDS of HYC plants to supplement IKC process is expected to be one of the efficient methods to cope with the environmental regulations.

关键词：重质油直接浓缩工艺 IKC 环境管理原油处理

Modified simultaneous integrated boost radiotherapy for an unresectable huge refractory pelvic tumor diagnosed as a rectal adenocarcinoma

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第48期20卷 18480-18486页

作者： Takuma Nomiya Hiroko Akamatsu Mayumi Harada Ibuki ota Yasuhito Hagiwara Mayumi Ichikawa Misako Miwa Shouhei Kawashiro Motohisa Hagiwara masahiro Chin Eiji Hashizume Kenji Nemoto Department of Radiation Oncology National Institute of Radiological Sciences Chiba 263-8555 Japan Department of Radiation Oncology Yamagata University Hospital Yamagata 990-8560 Japan Department of Surgery Nihonkai General Hospital Yamagata 990-8560 Japan

A clinical trial of radiotherapy with modified simultaneous integrated boost(SIB)technique against huge tumors was conducted.A 58-year-old male patient who had a huge pelvic tumor diagnosed as a rectal adenocarcinoma due to familial adenomatous polyposis was enrolled in this *** total dose of 77 Gy(equivalent dose in 2Gy/fraction)and 64.5 Gy was delivered to the center of the tumor and the surrounding area respectively,andapproximately 20%dose escalation was achieved with the modified SIB *** tumor with an initial maximum size of 15 cm disappeared 120 d after the start of the *** status of the patient improved from 4 to *** with modified SIB may be effective for patients with a huge tumor in terms of tumor shrinkage/disappearance,improvement of QOL,and prolongation of survival.

关键词： Clinical trial Image-guided radiotherapy Rectal neoplasms Quality of life Neoplasm recurrence

Techniques for Avoiding Saccular Extended Obstruction at the Anastomotic Site of Functional End-to-End Anastomosis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Surgical Science 2017年第7期8卷 305-311页

作者： Koichi Yoshida Kenichi Ietsugu Jyunpei Okamoto Saki Hayashi Yoshihide Asaumi Naohiro ota Hiroyuki Sugawara Satoshi Tabata masahiro Kaneki Mitsuaki Sakatoku Kaoru Kiyohara Department of Surgery Tonami General Hospital Toyama Japan

Saccular extended obstruction is generated when the anastomotic site of functional end-to-end anastomosis is extended saccularly and blocked by intestinal contents. This is a specific complication of functional end-to-end anastomosis. Saccular extended obstruction of the anastomotic site of func-tional end-to-end anastomosis causes postoperative intestinal obstruction. Saccular extended obstruction places a heavy burden on patients because surgery is necessary for treatment of intestinal obstruction due to saccular extended obstruction. However, saccular extended obstruction is not a commonly recognized complication. The greatest factor contributing to the development of saccular extended obstruction is an acute angle between the portions of the intestinal tract oral and aboral to the anastomotic site. When this angle approaches obtuse angle, preferably close to a straight line, stagnation of the intestinal contents does not occur at the anastomotic site of functional end-to-end anastomosis and saccular extended obstruction is avoided. For making the angle of anastomotic intestinal tracts obtuse or straight, it may be effective that the entry hole of stapling suture instrument creating the anastomotic stoma is closed perpendicular to the intestinal axis.

关键词： Functional End-to-End Anastomosis Stapling Anastomosis Anastomosis Postoperative Complication Intestinal Obstruction

Effects of Continuous Intravenous Infusion of Dexmedetomidine on the Duration of Spinal Anesthesia: A Prospective, Double-Blind, Randomized, Controlled Trial

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Anesthesiology 2018年第3期8卷 55-65页

作者： Mariko Watanabe masahiro Kanazawa Toshiyasu Suzuki Department of Anesthesiology Tokai University School of Medicine Isehara Japan Division of Anesthesia Subaru Health Insurance Society Ota Memorial Hospital Ota Japan

Background: Spinal anesthesia with sedation is a common anesthetic technique in infraumbilical surgeries. Dexmedetomidine has been widely used as a sedative during spinal anesthesia, and is recognized as an adjuvant that prolongs the duration of spinal anesthesia. We compared the effects of a continuous intravenous infusion of dexmedetomidine to provide intraoperative sedation on the duration of sensory and motor blockade induced by spinal anesthesia, with those of midazolam. Methods: A double-blind randomized controlled trial was performed on 40 patients, aged between 20 and 75 years, who requested intraoperative sedation, and were classified as American Society of Anesthesiologists (ASA) physical status I-II, and underwent elective surgeries under spinal anesthesia. After spinal anesthesia with 13 mg (2.6 ml) of 0.5% hyperbaric bupivacaine, patients were randomized to receive intravenous dexmedetomidine 3 μg/kg/h for 10 mins followed by an infusion of 0.5 μg/kg/h (Group D), or intravenous midazolam 0.15 mg/kg/h for 10 mins followed by an infusion of 0.025 mg/kg/h (Group M). Sedation was titrated to Observer’s Assessment of Alertness/Sedation (OAA/S) score of 3. Sensory and motor blockade was evaluated using the pinprick test and modified Bromage scale, respectively. Results: The time taken to achieve OAA/S score 3 was similar in the two groups. The maximal level of sensory blockade was 5.3 ± 1.3 min in group D and 4.1 ± 1.5 in group M (P = 0.03). No significant differences were observed in the time taken to achieve the maximal level or the two-segment regression time of sensory blockade between the two groups. The time to sensory regression to the L2 level was significantly longer in group D than in group M (234.6 ± 78.1 mins versus 172.4 ± 41.5 mins, respectively, P = 0.008). The time to motor regression to modified Bromage score 1 was significantly longer in group D than in group M (232.2 ± 79.3 versus 176.5 ± 48.8, respectively, P = 0.02). Conclusion: Continuou

关键词： Dexmedetomidine Spinal Anesthesia Sedation

Twenty-four hour intra-arterial infusion of 5-fluorouracil,cisplatin,and leucovorin is more effective than 6-hour infusion for advanced hepatocellular carcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2007年第2期13卷 280-284页

作者： Hidenari Nagai masahiro Kanayama Katsuya Higami Kouichi Momiyama Akiko Ikoma Naoki Okano Katsuhiko Matsumaru Manabu Watanabe Koji Ishii Yasukiyo Sumino Kazumasa Miki Division of Gastroenterology and Hepatology Toho University Medical Center Omori Hospital 6-11-1 Omorinishi Ota-ku Tokyo 143-8541 Japan

AIM. To evaluate the time dependence of intra-arterial 5-fluorouracil （5-FU） therapy for advanced hepatocellular carcinoma （aHCC）. METHODS： Thirty-seven adult Japanese patients who had aHCC and liver cirrhosis were treated with combined intra-arterial 5-FU, cisplatin （CDDP）, and leucovorin （LV）. The Japan Integrated Staging score （JIS score） of each patient was 3 or more. The patients were divided into two groups, alter which the 15 patients in group S were treated with 6-h infusion chemotherapy （LV at 12 mg/h, CDDP at 10 mg/h, and 5-FU at 250 mg/m^2 per 4 h） and the 22 patients in group L were treated with 24-h infusion chemotherapy （LV at 12 mg/h, CDDP at 10 mg/h, and 5-FU at 250 mg/m^2 per 22 h）. Continuous infusion chemotherapy was performed v/a the proper hepatic artery every 5 d for 4 wk using an implanted drug reservoir. RESULTS： The percentages of patients with a partial response after 4 wk of chemotherapy were 6.7% in group S and 31.8% in group L. The survival of group L was significantly better than that of group S, with the median survival time being 496 d in group L and 226 d in group S （P 〈 0.05）. CONCLUSION： Continuous 24-h intra-arterial infusion is more effective for aHCC and can markedly prolong survival time as compared to 6-h infusion.

关键词： 5-fluorouracil Cisplatin Advanced hepatocellular carcinoma Liver cirrhosis Intra-arterial chemotherapy