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Endoscopic diagnosis of cytomegalovirus gastritis after allogeneic hematopoietic stem cell transplantation

World Journal of Gastroenterology 2010年第23期16卷 2907-2912页

作者： Yasuo Kakugawa masahiro kami Takahisa Matsuda Yutaka Saito Sung-Won Kim Takahiro Fukuda Shin-ichiro Mori Tadakazu Shimoda Ryuji Tanosaki Daizo Saito Division of Endoscopy National Cancer Center Hospital(Japan) Division of Exploratory Research Institute of Medical ScienceUniversity of Tokyo Division of Hematopoietic Stem Cell Transplantation National Cancer Center Hospital(Japan) Clinical Laboratory Division National Cancer Center Hospital(Japan)

AIM:To clarify the endoscopic and clinical findings of cytomegalovirus(CMV) gastritis after allogeneic hematopoietic stem cell transplantation(allo-SCT).METHODS:Between 1999 and 2005,523 patients underwent allo-SCT at our hospital,and 115 of these patients with gastrointestinal symptoms underwent ***:CMV gastritis was diagnosed pathologically in seven patients(1.3%) with the other 108 patients serving as *** of the seven patients developed positive CMV antigenemia,and five complained of abdominal *** of abdominal pain preceded CMV antigenemia in four of the f ive *** examination showed oozing(n=2),erosion(n=6),and redness(n=5) in the seven patients with CMV gastritis,while the control patients showed oozing(n=3),erosion(n=24),and redness(n=100).Erosion and oozing were more frequently documented in patients with CMV gastritis compared with the controls,and the differences were statistically significant(P=0.0012 and 0.029,respectively).CMV inclusion bodies were documented in 12 of 14 biopsy specimens obtained from erosive lesions,while they were identif ied in 4 of 15 biopsy specimens obtained from lesions other than erosions(P=0.0025).CONCLUSION:This study suggests that erosion and oozing,as well as abdominal pain,are useful indicators in the diagnosis of CMV gastritis following allo-SCT.

关键词： Cytomegalovirus gastritis Hematopoietic stem cell transplantation Cytomegalovirus antigenemia Esophagogastroduodenoscopy Graft-versus-host disease

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Allergic reaction to anisakis-contaminated fish after the first administration of BNT162b2 mRNA vaccine:a case report

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Gastroenterology Report 2022年第1期10卷 650-652页

作者： Fumiue Harada Kana Yamamoto Tomoki Matsuda Chika Yamamoto Yuta Tani Mutsuko Ohnishi Morihito Takita Tetsuya Tanimoto masahiro kami Ryusaburo Shineha Department of Internal Medicine Soma Central HospitalSomaFukushimaJapan Department of Disaster and Comprehensive Medicine Fukushima Medical UniversityFukushimaFukushimaJapan Department of Radiation Health Management Fukushima Medical UniversityFukushimaFukushimaJapan Research Division Medical Governance Research InstituteMinatoTokyoJapan

Introduction SARS-CoV-2 vaccination is an effective means to prevent severe illness and death due to SARS-CoV-2 infection[1].Vaccine safety has been carefully monitored to be sure that the benefit outweighs the risk of adverse events(AEs).Common AEs of the BNT162b2 mRNA vaccine,for example,include fatigue(45%),headache(40%),and chills(28%)after the first administration in accordance with the adult phase Ⅲ clinical trial[1].

关键词： headache death administration

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How Do Weekly Magazines Provide Information on Urogenital Cancer to the Public in Aged Societies?

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Open Journal of Urology 2013年第6期3卷 246-247页

作者： Masayoshi Nagata Tomoko Matsumura masahiro kami Department of Urology National Center of Global Health and Medicine Tokyo Japan Division of Social Communication System for Advanced Clinical Research The Institute of Medical Science The University of Tokyo Tokyo Japan

Little information on cancer coverage rather than newspaper and television is available. Japanese weekly magazines have a circulation of over 2,700,000 per week. To examine how they delivered urogenital cancer information to the public, cancer-related articles and advertisements in six major Japanese weekly magazines from 2009 to 2010 was analyzed. 1.8% of total articles and advertisements were cancer-related. Prostate cancer (n = 119) was the second-most common topic, following lung cancer (n = 145), whereas only three articles were published on kidney or bladder cancer. The 53 articles on therapies for prostate cancer comprised radiotherapy (n = 29), surgery (n = 16), chemotherapy (n = 4), and others (n = 4). All 42 comments or interviews were cited in the article on prostate cancer, while 26 of them were attributed to only two famous doctors. Although cancer coverage in weekly magazines could be useful to spread information on prostate cancer, we should recognize their considerable bias based on a disproportionate emphasis.

关键词： Cancer Coverage Weekly Magazine Prostate Cancer

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Perforated appendiceal diverticulitis associated with appendiceal neurofibroma in neurofibromatosis type 1

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World Journal of Gastroenterology 2015年第33期21卷 9817-9821页

作者： Akihiko Ozaki Manabu Tsukada Kazuo Watanabe Masaharu Tsubokura Shigeaki Kato Tetsuya Tanimoto masahiro kami Hiromichi Ohira Yukio Kanazawa Division of Surgery Minamisoma Municipal General Hospital Division of Diagnostic Pathology Fukushima Pathology Laboratory Division of Social Communication System for Advanced Clinical Research Institute of Medical ScienceUniversity of Tokyo Division of Internal Medicine Soma Central Hospital Jyoban Hospital of Tokiwakai Group Division of Endoscopy Minamisoma Municipal General Hospital

An appendiceal neurofibroma(ANF) is a rare neoplasm associated with neurofibromatosis type 1(NF-1),an inheritable neurocutaneous disorder that involves multiple systems including the intraabdominal *** diverticulitis occasionally ruptures in the absence of intense abdominal pain,which can lead to serious *** reports highlight the association between appendiceal diverticulum and appendiceal neoplasms; however,there is still little information on the association between appendiceal diverticulitis and ANF in NF-1.A 51-year-old Japanese male with NF-1 was referred to the division of surgery for mild right lower quadrant *** was suspected he had perforated acute appendicitis with periappendiceal abscess based on clinical manifestations and findings of computed *** emergency appendectomy was *** pathological examination revealed diffusely proliferated tumor cells of a neurofibroma,coexistent with multiple appendiceal diverticulums,leading to the diagnosis ofperforated appendiceal diverticulitis associated with *** he developed a remnant abscess,he recovered with the conservative treatments of antibiotics and *** case suggests that appendiceal diverticulitis might be a complication of appendiceal involvement of NF-1,and that it occasionally ruptures in the absence of intense abdominal *** should recognize that NF-1 can cause various abdominal manifestations.

关键词： Appendiceal diverticulum Appendiceal diverticuliti

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日本新型冠状病毒肺炎传播初期阶段的流行现状及应对

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上海预防医学 2020年第4期32卷 314-319页

作者：王继伟谷本哲也赵天辰津田健司山下Erika 上昌广姜庆五复旦大学公共卫生学院上海200032 日本东京医疗管理研究所东京1080074

新型冠状病毒肺炎(COVID-19)于2019年12月开始出现病例报道以来,逐渐在全球范围内传播。日本国内的COVID-19病例从2020年1月中旬开始出现,并随时间推移持续增加,至2020年2月底前被认为是日本国内传播的初期阶段。本文描述截至2020年2月... 详细信息

新型冠状病毒肺炎(COVID-19)于2019年12月开始出现病例报道以来,逐渐在全球范围内传播。日本国内的COVID-19病例从2020年1月中旬开始出现,并随时间推移持续增加,至2020年2月底前被认为是日本国内传播的初期阶段。本文描述截至2020年2月底与日本有关的935例COVID-19病例的传播状况,包括从武汉包机接回的15例日本侨民感染者、大型邮轮“钻石公主”号中的696例感染者以及日本国内的224例感染者状况。同时总结了日本控制疫情扩散的措施,如限制针对新型冠状病毒(SARS-CoV-2)进行RT-PCR检测、降低不必要的前往医疗机构就诊的轻症患者人数、制订SARS-CoV-2感染咨询的准则、取消大型聚会、暂时关闭学校等。进一步提出了日本在预防与控制SARS-CoV-2传播中遇到的问题,如RT-PCR的检测迟缓、医务人员面临被感染风险、日本国内医疗保健服务体系存在地区差异、信息公开与管理存在混乱等。通过以上介绍,加深对COVID-19在日本及全球流行特点的理解,为全球控制COVID-19疫情提供借鉴。

关键词：新型冠状病毒肺炎日本传播初期阶段冠状病毒科 SARS-CoV-2病毒 “钻石公主”号

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