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Endoscopic naso-pancreatic drainage for the treatment of pancreatic fistula occurring after LDLT

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World Journal of Gastroenterology 2011年第30期17卷 3560-3564页

作者： Akihisa Nagatsu Toshiya Kamiyama Satoru Todo masahiko taniguchi Tomomi Suzuki Hiroyuki Furukawa Tsuyoshi Shimamura Kenichiro Yamashita Hiroshi Kawakami Daisuke Abo Department of General Surgery Graduate School of MedicineHokkaido UniversityN-15W-7Kita-ku060-8638 SapporoJapan Department of Organ Transplantation and Regeneration Graduate School of MedicineHokkaido UniversityN-15W-7Kitaku060-8638 SapporoJapan Division of Organ Transplantation Graduate School of MedicineHokkaido UniversityN-15W-7Kita-ku060-8638 SapporoJapan Department of Molecular Surgery Graduate School of MedicineHokkaido UniversityN-15W-7Kita-ku060-8638 SapporoJapan Department of Gastroenterology Graduate School of MedicineHokkaido UniversityN-15W-7Kita-ku060-8638 SapporoJapan Department of Radiology Graduate School of MedicineHokkaido UniversityN-15W-7Kita-ku060-8638 SapporoJapan

Pancreatic fistula is a quite rare complication in patients who undergo living donor liver transplantation(LDLT).However,in the cases that show pancreatic fistula,the limited volume of the graft and the resultant inadequate liver function may complicate the management of the fistula.As a result,the pancreatic fistula may result in the death of the patient.We present 2 cases in whichendoscopic treatment was effective against pancreatic fistulas that developed after LDLT.In case 1,a 61-yearold woman underwent LDLT for primary biliary cirrhosis.Because of a portal venous thrombus caused by a splenorenal shunt,the patient underwent portal vein reconstruction,and a splenorenal shunt was ligated on postoperative day(POD)7.The main pancreatic duct was injured during the manipulation to achieve hemostasis,thereby necessitating open drainage.However,discharge of pancreatic fluid continued even after POD 300.Endoscopic naso-pancreatic drainage(ENPD)was performed,and this procedure resulted in a remarkable decrease in drain output.The refractory pancreatic fistula healed on day 40 after ENPD.In case 2,a 58-year-old man underwent LDLT for cirrhosis caused by the hepatitis C virus.When the portal vein was exposed during thrombectomy,the pancreatic head was injured,which led to the formation of a pancreatic fistula.Conservative therapy was ineffective;therefore,ENPD was performed.The pancreatic fistula healed on day 38 after ENPD.The findings in these 2 cases show that endoscopic drainage of the main pancreatic duct is a less invasive and effective treatment for pancreatic fistulas that develop after LDLT.

关键词：保守治疗肝移植活体引流内镜生后鼻静脉血栓

Hepatic schwannoma:Imaging findings on CT,MRI and contrast-enhanced ultrasonography

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World Journal of Gastroenterology 2012年第35期18卷 4967-4972页

作者： Yu Ota Kazunobu Aso Kenji Watanabe Takahiro Einama Koji Imai Hidenori Karasaki Ryuji Sudo Yosui Tamaki Mituyoshi Okada Yosihiko Tokusashi Toru Kono Naoyuki Miyokawa Masakazu Haneda masahiko taniguchi Hiroyuki Furukawa Division of Metabolism and Biosystemic Science Department of MedicineAsahikawa Medical University Division of Gastroenterologic and General Surgery Department of SurgeryAsahikawa Medical University Department of Pathology Asahikawa Medical University

A primary benign schwannoma of the liver is extremely rare and is difficult to preoperatively discriminate from a malignant tumor.We compared the imaging and pathological findings,and examined the possibility of preoperatively diagnosing a benign liver schwannoma.A 72-year-old woman was admitted to our hospital because of a 4.6-cm mass in the liver.A malignant tumor was suspected,and a right hepatectomy was performed.After this,the diagnosis of a primary benign schwannoma of the liver was made through pathological examination.Contrast-enhanced ultrasonography(CEUS) with Sonazoid showed minute blood flows into the septum and solid areas of the tumor in the vascular phase;most likely due to increased arterial flow associated with infiltration of chronic inflammatory cells.In the postvascular phase,CEUS showed contrast defect of cystic areas and delayed enhancement of solid areas;most likely due to aggregation of siderophores.Because discriminating between a benign and malignant schwannoma of the liver is difficult,surgery is generally recommended.However,the two key findings from CEUS may be useful in discriminating ancient schwannoma by recognizing the hemorrhage involved in the secondary degeneration and aggregation of siderophores.

关键词：肝脏神经造影超声影像学 MRI CT 病理检查

Clinicopathological features of small nonfunctioning pancreatic neuroendocrine tumors

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World Journal of Gastroenterology 2014年第47期20卷 17949-17954页

作者： Mariko Furukori Koji Imai Hidenori Karasaki Kenji Watanabe Kensuke Oikawa Naoyuki Miyokawa masahiko taniguchi Hiroyuki Furukawa Division of Gastroenterological and General Surgery Department of SurgeryAsahikawa Medical UniversityHokkaido 078-8510Japan Department of Surgery Sapporo Higashi Tokushukai HospitalSapporo cityHokkaido 065-0033Japan Department of Surgical Pathology Asahikawa Medical College HospitalHokkaido 078-8510Japan

AIM:To present our experiences in studying the clinicopathological features of small nonfunctioning pancreatic neuroendocrine tumors(NF-p NETs).METHODS:The subjects included 9 patients with NFp NETs who underwent pancreatectomy between April1996 and September 2012.The surgical procedure,histopathological findings,and prognosis were assessed.RESULTS:All tumors were incidentally detected by computed tomography.The median diameter was 10mm(5-32 mm).One patient was diagnosed with von Hippel-Lindau disease,and the others were sporadiccases.For the histopathological findings,7 patients were G1;1 patient was G2;and 1 patient,whose tumor was 22 mm,had neuroendocrine carcinoma(NEC).One patient who had a tumor that was 32 mm had direct invasion to a regional lymph node and 1 patient with NEC,had regional lymph node metastases.Six of the 7 patients with sporadic NF-p NETs,excluding the patient with NEC,had tumors that were smaller than10 mm.Tumors smaller than 10 mm showed no malignancy and lacked lymph node metastasis.CONCLUSION:Sporadic NF-p NETs smaller than 10mm tend to have less malignant potential.These findings suggest that lymphadenectomy may be omitted for small NF-p NETs after further investigation.

关键词： Pancreatic neuroendocrine tumor Pancreatic neuroen

Hepatic clearance measured with ^(99m)Tc-GSA single-photon emission computed tomography to estimate liver fibrosis

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World Journal of Gastroenterology 2014年第44期20卷 16714-16720页

作者： masahiko taniguchi Atsutaka Okizaki Kenji Watanabe Koji Imai Koichiro Uchida Takahiro Einama Noriyuki Shuke Naoyuki Miyokawa Hiroyuki Furukawa Division of Gastroenterologic and General Surgery Department of Surgery Asahikawa Medical College Department of Radiology Asahikawa Medical College Department of Pathology Asahikawa Medical College

AIM: To evaluate the clinical utility of hepatic clearance(HC) measured with technetium-99m-diethylenetriaminepenta-acetic acid-galactosyl human serum albumin(99mTc-GSA) single-photon emission computed tomography(SPECT) to estimate the degree of liver fibrosis.METHODS:Seventy-eight consecutive patients who underwent initial hepatectomy due to hepatocellular carcinoma were enrolled in this study.Indocyanine green clearance(ICG R15),quantitative indices estimated by 99mTc-GSA[the receptor index(LHL15 and HH15)and HC via SPECT analysis],and conventional liver function tests were performed before hepatectomy.Correlations among the quantitative indices for liver functional reserve,conventional liver function tests,andthe degree of liver fibrosis were evaluated.RESULTS:The degree of liver fibrosis was correlated with ICG R15,HH15,LHL15,and HC.HC showed the best correlation with conventional liver function tests.According to multivariate analysis,HC and LHL15 were significant independent predictors of severe fibrosis.HC was the most valuable index for predicting severe fibrosis.CONCLUSION:HC measured with 99mTc-GSA SPECT is a reliable index for assessing liver fibrosis before hepatectomy.

关键词： Fibrosis Technetium-99m-diethylenetri-aminepenta-a

Field induced Chern insulating states in twisted monolayer–bilayer graphene

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Chinese Physics B 2024年第6期33卷 69-73页

作者：王政文韩英卓 Kenji Watanabe Takashi taniguchi 姜宇航毛金海 School of Physical Science and CAS Center for Excellence in Topological Quantum Computation University of Chinese Academy of SciencesBeijing 100049China College of Materials Science and Optoelectronic Technology Center of Materials Science and Optoelectronics EngineeringUniversity of Chinese Academy of SciencesBeijing 100049China Advanced Materials Laboratory National Institute for Materials ScienceTsukuba 305-0044Japan

Unraveling the mechanism underlying topological phases, notably the Chern insulators(Ch Is) in strong correlated systems at the microscopy scale, has captivated significant research interest. Nonetheless, Ch Is harboring topological information have not always manifested themselves, owing to the constraints imposed by displacement fields in certain experimental configurations. In this study, we employ density-tuned scanning tunneling microscopy(DT-STM) to investigate the Ch Is in twisted monolayer–bilayer graphene(t MBG). At zero magnetic field, we observe correlated metallic states.While under a magnetic field, a metal–insulator transition happens and an integer Ch I is formed emanating from the filling index s = 3 with a Chern number C = 1. Our results underscore the pivotal role of magnetic fields as a powerful probe for elucidating topological phases in twisted Van der Waals heterostructures.

关键词： Chern insulators strong correlation effects two-dimensional van der Waals heterostructure density-tuned scanning tunneling microscopy(DT-STM)

Literature Review on Support for Children and Families Experiencing Parental Bereavement

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Open Journal of Nursing 2024年第4期14卷 139-163页

作者： Rurie Namiki Keita Sasaki Iku taniguchi Rie Wakimizu Department of Nursing Science Graduate School of Comprehensive Human Sciences University of Tsukuba Ibaraki Japan Department of Child Health Care Nursing Division of Health Innovation and Nursing Faculty of Medicine University of Tsukuba Ibaraki Japan

Purpose: This study aimed to understand the actual nursing support in a wide perspective by reviewing overseas literature on support for children who have experienced parental bereavement and their families. The goal was to identify future challenges in nursing support in clinical practice in Japan. Method: Literature searchable as of May 2023 was retrieved using PubMed, resulting in 11 relevant articles. Result: The results revealed the following: 1) For support provided to children, 13 codes were condensed into 5 subcategories and 4 categories. 2) For support provided to families, 36 codes were condensed into 11 subcategories and 4 categories. Conclusion: Open communication was found to be essential for supporting children and their families who have experienced parental bereavement. Moreover, involvement of multiple professions facilitated the provision of specialized support to address diverse needs of children and families, playing a crucial role in overcoming grief. Additionally, the effectiveness of support systems for bereaved families highlighted the need for nursing professionals in Japan to gain knowledge through learning opportunities and to establish a multi-disciplinary approach to support, thus indicating future challenges in nursing support.

关键词： Terminal Care Family Support Child Parental Death Palliative Care

Impact of device resistances in the performance of graphene‑based terahertz photodetectors

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Frontiers of Optoelectronics 2024年第2期17卷 87-97页

作者： O.Castelló Sofía M.López Baptista K.Watanabe T.taniguchi E.Diez J.E.Velázquez-Pérez Y.M.Meziani J.M.Caridad J.A.Delgado-Notario Department of Applied Physics University of Salamanca37008 SalamancaSpain Unidad de Excelencia en Luz y Materia Estructurada(LUMES) University of Salamanca37008 SalamancaSpain Research Center for Electronic and Optical Materials National Institute for Materials Science1-1 NamikiTsukuba 305-0044Japan Research Center for Materials Nanoarchitectonics National Institute for Materials Science1-1 NamikiTsukuba 305-0044Japan Nanotechnology Group USAL-NanolabUniversity of Salamanca37008 SalamancaSpain

In recent years,graphene field-effect-transistors(GFETs)have demonstrated an outstanding potential for terahertz(THz)photodetection due to their fast response and high-sensitivity.Such features are essential to enable emerging THz applications,including 6G wireless communications,quantum information,bioimaging and security.However,the overall performance of these photodetectors may be utterly compromised by the impact of internal resistances presented in the device,so-called access or parasitic resistances.In this work,we provide a detailed study of the influence of internal device resistances in the photoresponse of high-mobility dual-gate GFET detectors.Such dual-gate architectures allow us to fine tune(decrease)the internal resistance of the device by an order of magnitude and consequently demonstrate an improved responsivity and noise-equivalent-power values of the photodetector,respectively.Our results can be well understood by a series resistance model,as shown by the excellent agreement found between the experimental data and theoretical calculations.These findings are therefore relevant to understand and improve the overall performance of existing high-mobility graphene photodetectors.

关键词： Graphene THz Photodetector Field-effect transistor Plasmonic

THREE NEW FUROCOUMARINS FROM NOTOPTERYGIUM INCISUM TING

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Chinese Chemical Letters 1994年第7期5卷 593-596页

作者： Yong Qing XIAO Xiao Hong LIU, and You Fu SUN(Institute of Chinese Materia Medica, Academy of Traditional Chinese Medicine,beijing 1O0700)Kimiye BASA. masahiko taniguchi and Mitsugi KOZAWA(Osaka University of Pharmaceutical Sciences. Osaka 58O Japan)

From the EtOAc extract of the underground part of notopterygium incisum Ting.,three new furocoumarins. 5-[(2E)-3,7-dimethyl-5-ethylox-2.,6-octadienyloxylpsoralen named ethylnotopterol(A),5-(2E,5E)-3,7-dimethyl-7-dimet...

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仗剑斩龙的诗人们——中唐诗歌中的龙神与祭祀

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南京师范大学文学院学报 2024年第1期 144-166页

作者：谷口高志陈文辉(译) 日本佐贺大学教育系佐贺县佐贺8408502 吉林外国语大学国际传媒学院吉林长春130117

随着佛教的渗透,在唐代,特别是中唐前后“河伯”被龙神代替,民间的龙神祭祀开始出现在诗文作品中,但其祭祀被定位为“淫祀”的一种。白居易和韩愈在《黑潭龙》《题炭谷湫祠堂》中将龙神的淫祀问题与奸臣、天子权威问题相关联,从中能够... 详细信息

随着佛教的渗透,在唐代,特别是中唐前后“河伯”被龙神代替,民间的龙神祭祀开始出现在诗文作品中,但其祭祀被定位为“淫祀”的一种。白居易和韩愈在《黑潭龙》《题炭谷湫祠堂》中将龙神的淫祀问题与奸臣、天子权威问题相关联,从中能够看出中唐时期诗人们的危机感和问题意识。而从盛唐到中唐,“代表国家安宁的龙”的象征性的崩坍,在杜甫的《奉同郭给事汤东灵湫作》诗作中可以看到。中唐时期洞庭湖水域作为非祭祀对象的恶龙等妖物的栖息地,频繁地出现在士人们的诗文中。水界的混乱,成为士人们心中世界秩序混乱的类比,进而与现实中的奸臣、朝廷权威问题相重合,激发了诗人们“斩龙”“驱龙”的愿望。概而言之,中唐时期诗人们出于自己官僚身份的自我认知以及对朝廷、世界的责任感和自负心,对危及朝廷的淫祀、恶龙等的存在产生了危机感和焦躁感,这种问题意识促使他们将其表现在了诗文作品中。

关键词：龙神祭祀淫祀白居易韩愈