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Clinicopathological features of small nonfunctioning pancreatic neuroendocrine tumors

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World Journal of Gastroenterology 2014年第47期20卷 17949-17954页

作者： Mariko Furukori Koji Imai Hidenori Karasaki Kenji Watanabe Kensuke Oikawa Naoyuki Miyokawa masahiko taniguchi Hiroyuki Furukawa Division of Gastroenterological and General Surgery Department of SurgeryAsahikawa Medical UniversityHokkaido 078-8510Japan Department of Surgery Sapporo Higashi Tokushukai HospitalSapporo cityHokkaido 065-0033Japan Department of Surgical Pathology Asahikawa Medical College HospitalHokkaido 078-8510Japan

AIM: To present our experiences in studying the clinicopathological features of small nonfunctioning pancreatic neuroendocrine tumors (NF-pNETs).

关键词： Pancreatic neuroendocrine tumor Pancreatic neuroendocrine carcinoma Nonfunctioning Lymphadenectomy Treatment

Hepatic clearance measured with ^(99m)Tc-GSA single-photon emission computed tomography to estimate liver fibrosis

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World Journal of Gastroenterology 2014年第44期20卷 16714-16720页

作者： masahiko taniguchi Atsutaka Okizaki Kenji Watanabe Koji Imai Koichiro Uchida Takahiro Einama Noriyuki Shuke Naoyuki Miyokawa Hiroyuki Furukawa Division of Gastroenterologic and General Surgery Department of Surgery Asahikawa Medical College Department of Radiology Asahikawa Medical College Department of Pathology Asahikawa Medical College

AIM: To evaluate the clinical utility of hepatic clearance(HC) measured with technetium-99m-diethylenetriaminepenta-acetic acid-galactosyl human serum albumin(99mTc-GSA) single-photon emission computed tomography(SPECT) to estimate the degree of liver ***:Seventy-eight consecutive patients who underwent initial hepatectomy due to hepatocellular carcinoma were enrolled in this *** green clearance(ICG R15),quantitative indices estimated by 99mTc-GSA[the receptor index(LHL15 and HH15)and HC via SPECT analysis],and conventional liver function tests were performed before *** among the quantitative indices for liver functional reserve,conventional liver function tests,andthe degree of liver fibrosis were ***:The degree of liver fibrosis was correlated with ICG R15,HH15,LHL15,and *** showed the best correlation with conventional liver function *** to multivariate analysis,HC and LHL15 were significant independent predictors of severe *** was the most valuable index for predicting severe ***:HC measured with 99mTc-GSA SPECT is a reliable index for assessing liver fibrosis before hepatectomy.

关键词： Fibrosis Technetium-99m-diethylenetri-aminepenta-acetic acid-galactosyl human serum albu-min Single-photon emission computed tomography Hepatic clearance Liver resection

Endoscopic naso-pancreatic drainage for the treatment of pancreatic fistula occurring after LDLT

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World Journal of Gastroenterology 2011年第30期17卷 3560-3564页

作者： Akihisa Nagatsu Toshiya Kamiyama Satoru Todo masahiko taniguchi Tomomi Suzuki Hiroyuki Furukawa Tsuyoshi Shimamura Kenichiro Yamashita Hiroshi Kawakami Daisuke Abo Department of General Surgery Graduate School of MedicineHokkaido UniversityN-15W-7Kita-ku060-8638 SapporoJapan Department of Organ Transplantation and Regeneration Graduate School of MedicineHokkaido UniversityN-15W-7Kitaku060-8638 SapporoJapan Division of Organ Transplantation Graduate School of MedicineHokkaido UniversityN-15W-7Kita-ku060-8638 SapporoJapan Department of Molecular Surgery Graduate School of MedicineHokkaido UniversityN-15W-7Kita-ku060-8638 SapporoJapan Department of Gastroenterology Graduate School of MedicineHokkaido UniversityN-15W-7Kita-ku060-8638 SapporoJapan Department of Radiology Graduate School of MedicineHokkaido UniversityN-15W-7Kita-ku060-8638 SapporoJapan

Pancreatic fistula is a quite rare complication in patients who undergo living donor liver transplantation(LDLT).However,in the cases that show pancreatic fistula,the limited volume of the graft and the resultant inadequate liver function may complicate the management of the *** a result,the pancreatic fistula may result in the death of the *** present 2 cases in whichendoscopic treatment was effective against pancreatic fistulas that developed after *** case 1,a 61-yearold woman underwent LDLT for primary biliary *** of a portal venous thrombus caused by a splenorenal shunt,the patient underwent portal vein reconstruction,and a splenorenal shunt was ligated on postoperative day(POD)*** main pancreatic duct was injured during the manipulation to achieve hemostasis,thereby necessitating open ***,discharge of pancreatic fluid continued even after POD *** naso-pancreatic drainage(ENPD)was performed,and this procedure resulted in a remarkable decrease in drain *** refractory pancreatic fistula healed on day 40 after *** case 2,a 58-year-old man underwent LDLT for cirrhosis caused by the hepatitis C *** the portal vein was exposed during thrombectomy,the pancreatic head was injured,which led to the formation of a pancreatic *** therapy was ineffective;therefore,ENPD was *** pancreatic fistula healed on day 38 after *** findings in these 2 cases show that endoscopic drainage of the main pancreatic duct is a less invasive and effective treatment for pancreatic fistulas that develop after LDLT.

关键词： Pancreatic fistula Endoscopic treatment Living donor liver transplantation Complications

Hepatic schwannoma:Imaging findings on CT,MRI and contrast-enhanced ultrasonography

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World Journal of Gastroenterology 2012年第35期18卷 4967-4972页

作者： Yu Ota Kazunobu Aso Kenji Watanabe Takahiro Einama Koji Imai Hidenori Karasaki Ryuji Sudo Yosui Tamaki Mituyoshi Okada Yosihiko Tokusashi Toru Kono Naoyuki Miyokawa Masakazu Haneda masahiko taniguchi Hiroyuki Furukawa Division of Metabolism and Biosystemic Science Department of MedicineAsahikawa Medical University Division of Gastroenterologic and General Surgery Department of SurgeryAsahikawa Medical University Department of Pathology Asahikawa Medical University

A primary benign schwannoma of the liver is extremely rare and is difficult to preoperatively discriminate from a malignant *** compared the imaging and pathological findings,and examined the possibility of preoperatively diagnosing a benign liver schwannoma.A 72-year-old woman was admitted to our hospital because of a 4.6-cm mass in the liver.A malignant tumor was suspected,and a right hepatectomy was *** this,the diagnosis of a primary benign schwannoma of the liver was made through pathological ***-enhanced ultrasonography(CEUS) with Sonazoid showed minute blood flows into the septum and solid areas of the tumor in the vascular phase;most likely due to increased arterial flow associated with infiltration of chronic inflammatory *** the postvascular phase,CEUS showed contrast defect of cystic areas and delayed enhancement of solid areas;most likely due to aggregation of *** discriminating between a benign and malignant schwannoma of the liver is difficult,surgery is generally ***,the two key findings from CEUS may be useful in discriminating ancient schwannoma by recognizing the hemorrhage involved in the secondary degeneration and aggregation of siderophores.

关键词： Liver schwannoma Contrast-enhanced ul-trasonography Liver resection

THREE NEW FUROCOUMARINS FROM NOTOPTERYGIUM INCISUM TING

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Chinese Chemical Letters 1994年第7期5卷 593-596页

作者： Yong Qing XIAO Xiao Hong LIU, and You Fu SUN(Institute of Chinese Materia Medica, Academy of Traditional Chinese Medicine,beijing 1O0700)Kimiye BASA. masahiko taniguchi and Mitsugi KOZAWA(Osaka University of Pharmaceutical Sciences. Osaka 58O Japan)

From the EtOAc extract of the underground part of notopterygium incisum Ting.,three new furocoumarins. 5-[(2E)-3,7-dimethyl-5-ethylox-2.,6-octadienyloxylpsoralen named ethylnotopterol(A),5-(2E,5E)-3,7-dimethyl-7-dimet...

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Limits to Resources,Economic Growth and Happiness

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Journal of Shanghai Jiaotong university(Science) 2012年第3期17卷 364-369页

作者： taniguchi Shoji Graduate School of Environmental Studies Tohoku UniversitySendai 980-8579Japan

Terrible scenario for the future aspect of our society was issued by ＂The Limits to Growth＂. Basic problems that we confront are the restricted natural resources and the environment. Regarding the resources, the overall average of the reserve/production ratio is predicted to fall below 10 years by 2040. Aggressive developments of mines based on the sense of urgency for metal resources cause strong conftiction with the environment and the people living there. Resultantly, urban mine becomes more realistic than before. From the view point of ecological foot print, 5.3 globes are needed if all the people living in the world attain the affluent life same as USA. On the other hand, it is clear that we can get larger utility by smaller goods if our scale of satisfaction is reduced. We have to notice that happiness is our ultimate purpose, economy and industry are intermediate, and natural resources support the all from the basis.

关键词： Leconomic growth natural resources happiness environmental load assessment

Effects of Freestream Turbulence on Bypass Transition of Separated Boundary Layer on Low-Pressure Turbine Airfoils

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Journal of Thermal Science 2012年第3期21卷 230-235页

作者： Hideo taniguchi Hiroshi Sakai Ken-ichi Funazaki Department of Mechanical Systems Engineering Faculty of EngineeringIwate University

This paper presents experimental studies on bypass transition of separated boundary layer on low-pressure turbine airfoils,focusing on the effects of freestream turbulence on the transition ***-wire probe measurements are performed on the suction side of an airfoil in the low-pressure linear turbine cascade at several Reynolds number *** turbulence is enhanced by use of turbulence grid located upstream of the *** results of this experimental study show that the location of boundary layer separation does not strongly de-pend on the freestream turbulence ***,as the freestream turbulence level increases,the size of separa-tion bubble becomes small and the location of turbulent transition moves *** size of separation bubble becomes small as the Reynolds number *** low freestream turbulence intensity,the velocity fluctuation due to Kelvin-Helmholtz instability is observed clearly in the shear layer of the separation *** high frees-tream turbulence intensity,the streak structures appear upstream of the separation location,indicating bypass transition of attached boundary layer occurs at high Reynolds number.

关键词： Aeroengine Low-Pressure Turbine Bypass Transition Separation Bubble

Observation of~100%valley-coherent excitons in monolayer MoS_(2) through giant enhancement of valley coherence time

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Light(Science & Applications) 2023年第8期12卷 1644-1650页

作者： Garima Gupta Kenji Watanabe Takashi taniguchi Kausik Majumdar Department of Electrical Communication Engineering Indian Institute of ScienceBangaloreIndia Research Center for Functional Materials National Institute for Materials ScienceTsukubaJapan international Center for Materials Nanoarchitectonics National Institute for Materials ScienceTsukubaJapan

In monolayer transition metal dichalcogenide semiconductors,valley coherence degrades rapidly due to a combination of fast scattering and inter-valley exchange *** leads to a sub-picosecond valley coherence time,making coherent manipulation of exciton a highly challenging task Using monolayer MoS_(2) sandwiched between top and bottom graphene,here we demonstrate fully valley-coherent excitons by observing~100%degree of linear polarization in steady state *** is achieved in this unique design through a combined effect of(a)suppression in exchange interaction due to enhanced dielectric screening,(b)reduction in exciton lifetime due to a fast inter-layer transfer to graphene,and(c)operating in the motional narrowing *** disentangle the role of the key parameters affecting valley coherence by using a combination of calculation(solutions of Bethe-Salpeter and Maiallle-Silva-Sham equations)and a careful choice of design of experiments using four different stacks with systematic variation of screening and exciton *** the best of our knowledge,this is the first report in which the excitons are found to be valley coherent in the entire lifetime in monolayer semiconductors,allowing optical readout of valley coherence possible.

关键词： coherent monolayer lifetime

PREPARATION OF PHOTOFUNCTIONAL POLYMER THIN FILMS BY LANGMUIR-BLODGETT TECHNIQUE

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Chinese Journal of Polymer Science 1999年第1期17卷 75-79页

作者： Tokuji Miyashita Tatsuo taniguchi Yoshihito Fukasawa Institute for Chemical Reaction Science Tohoku University Sendai 980-8577 JapanInstitute for Chemical Reaction Science Tohoku University Sendai 980-8577 JapanInstitute for Chemical Reaction Science Tohoku University Sendai 980-8577 Japan

Polymer LB films containing photofuntional groups were prepared by the copolymerization of N-dodecylacrylamide (DDA), which has an excellent property to form a stable monolayer and LB multilayerswith photofunctional monomers. Tris(2, 2'-bipyridine) ruthenium complex, Ru(bpy)_3^(2+), one of the most well-known redox-active sensitizer, was incorporated into the DDA copolymer. The photogalvanic effect based onthe photoinduced electron transfer using the ruthenium complex in the polymer LB monolayer was discussed.

关键词： Photofunctional polymer Polymer LB film, N-Dodecylacrylamide Ruthenium complex