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Intravesical Non-Alkalinized Lidocaine Instillation for Interstitial Cystitis/Bladder Pain Syndrome Patients

Open Journal of Urology 2012年第4期2卷 223-226页

作者： Teiichiro Aoyagi masaaki Tachibana Tokyo Medical University Ibaraki Medical Center Inashiki Japan

Purpose: The effectiveness of daily or weekly instillation of non-alkalinized lidocaine for patients suffering interstitial cystitis and/or bladder pain syndrome was evaluated retrospectively. Patients and methods: Five female patients (40 - 71 years old) diagnosed as interstitial cystitis by cystoscopic findings and a 68 year-old bladder pain syndrome patient were enrolled. All patients, having interstitial cystitis, had undergone hydrodistention therapy previously and had not improved their symptoms by empirical therapies. Daily or weekly (upon their severity of symptoms) intravesical instillation of 20 ml of 4% non-alkalinized (pH 6.0 - 7.0) lidocaine solution was performed for several times, and patients were asked to keep them in the bladder as long as two hours each time. Previous medications such as anti-cholinergic drugs and analgesics were continued according to patient's requirements and symptoms. The treatment effect was evaluated comparing O'Leary-Sant Symptom Index for interstitial cystitis patients and visual analog pain scale before and after the series of lidocaine therapies. Results: Instillation was made 6 to 16 times. Patients with interstitial cystitis improved their symptoms from O'Leary-Sant Symptom Index 17.5 to 10, Problem Index from 14.8 to 6 in an average. Crouching pain disappeared in all these patients after the instillation therapy. Severe interstitial cystitis findings on cystoscopy disappeared completely in one patient after the therapy. One patient having bladder pain syndrome reduced her analgesics use, and bladder-filling pain decreased from 7 to 3 as a visual analog scale score. One patient complained palpitation at 11th instillation and abandoned treatment thereafter, otherwise, none of these patients showed side effect concerning lidocaine toxicity. Conclusions: Intravesical non-alkalinized lidocaine instillation therapy for interstitial cystitis/bladder pain syndrome patients were an easy, safe and effective treatment.

关键词： Bladder Pain Syndrome Interstitial Cystitis Lidocaine Instillation Therapy

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RECENT DEVELOPMENTS IN LOW-COORDINATE ORGANO PHOSPHORUS COMPOUNDS

RECENT DEVELOPMENTS IN LOW-COORDINATE ORGANO PHOSPHORUS COMP...

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第六届全国磷化学化工学术讨论会

作者： masaaki Yoshifuii Department of Chemistry Graduate School of ScienceTohoku University Sendai 980-8578 Japan

Sterically protected and multiple-bonded organophosphorus compounds are currently of interest. Utilizing the 2,4,6-tri-t-butylphenyl group (abbreviated to Mes*) as a protecting group, we have been successful in isolat...

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Web Service and Visualization for Higher Education Information Providing Service

Web Service and Visualization for Higher Education Informati...

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IEEE BEIJING SECTION(跨国电气电子工程师学会北京分会)

作者： masaaki Ida National Institution for Academic Degrees and University Evaluation 1-29-1 Gakuen-nishimachi

Important and urgent issue of higher education institutions is to provide service to their students,staffs and public with useful education *** this paper analyzing structure of higher education information,development and improvement of the education information providing service is examined that consists of syllabus database,XML web service, curriculum analyzing system,multivariable analysis methods and other web *** correspondence analysis is utilized in text mining in order to deepen global understanding on the characteristics of categorized and accumulated textual information included in *** paper also presents the visualization method for higher education curriculum textual information.

关键词： Service sciences web service XML and databases web technologies and information management information retrieval text mining correspondence analysis curriculum analysis evaluation visualization

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Prostate-specific antigen screening for prostate cancer： benefits for patients with highly aggressive prostate cancer

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Asian Journal of Andrology 2013年第2期15卷 218-220,I0006页

作者： Hui-Jie Jia Yang Li Jin-Guo Wang Ling Zhang Hai-Tao Zhang Xue-Jian Zhao masaaki Kuwahara Department of Pathophysiology Prostate Diseases Prevention and Treatment Research Centre Norman Bethune College of Medicine Jilin University Changchun 130021 China Laboratory of Transplantation and Immunology Xuzhou Medical College Xuzhou 221000 China Department of Pathology and Laboratory Medicine and Tulane Cancer Center Tulane University School of Medicine New Orleans LA 70112 USA Sendal Reno-Urological Clinic 3-1-32 Minami-yoshinari Sendal 9893204 Japan

The US Preventive Services Task Force （USPSTF） analyzed the benefits and harms of prostate specific antigen （PSA）- based screening for prostate cancer （PCa）. The Grade ＇D＇ recommendation of the USPSTF was based mainly on the Prostate, Lung, Colorectal, and Ovarian （PLCO） study in the United States. That result showed only a small reduction in PCa mortality. However, the data from the International Agency for Research on Cancer （IARC） iUustrated the PCa mortality rate （MR） decreased marked. To avoid the over-diagnosis and over-treatment, the American Cancer Society has changed its strategy and updated its guidance. The USPSTF neglected the aggressive PCa accounted for more then 30% of all PCa. Highly aggressive PCa can be diagnosed by PSA screening combined with Gleason grade. We hope that the USPSTF changes the ＇D＇ recommendation for PSA screening.

关键词： UNITED-STATES RISK-FACTORS MORTALITY COMPLICATIONS POPULATION CHINESE LEAD

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World Maps Originating in Asia

World Maps Originating in Asia

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北京论坛（2005）文明的和谐与共同繁荣——全球化视野中亚洲的机遇与发展

作者： masaaki Sugiyama Kyoto University Japan

The First Afro-Eurasian Map in Human History A single map of vast proportions The map you have before you is known as the Hunyijiangli lidai guodu zhitu (which has been translated in English as the Map ofIntegrated Lands and Regions of Historical Countries and Capitals). That such a map exists in the collection of the library of Ryukoku University is today well *** map was previously owned by the Otani family ofNishi-

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Trend of Cathodic E-Coat for Automobiles

Trend of Cathodic E-Coat for Automobiles

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2nd Pacific Coating Forum

作者： masaaki Nakashio SHINTO PAINT Co. LTDResearch ＆ Development Department 10-736-ChomeMinamitsukaguchiAmagasakiHyogo661Japan

＜正＞1. Introduction Nowadays, key words on automotive coatings in Japan are Cost-down, Variety, New Functions, Added Value as well as Global environment protection. Under such circumstance, our R/D of cathodic E-Coat must work for various requirements from each key-word. For example, We should be more cost-conscious even at developing higher quality products. Higher film performances such as corrosion resistance, throwing power and weatherability are always important theme of our R/D. For friendly Earth, we have to develop Heavy-metal-free, low VOC and HAPS-free CED. We have also to save global energy and resources, by developing reasonable process in oven-temperature, pretreatment and even ED process. We are developing those E-coat to meet not only customer’s requirements but also global needs.

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Viabahn Stent Graft for Inadvertent Insertion of a Central Venous Catheter in the Subclavian Artery

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World Journal of Cardiovascular Diseases 2022年第7期12卷 397-402页

作者： Yuchen Cao masaaki Koide Masakazu Watanabe Division of Cardiovascular Surgery Seirei Hamamatsu General Hospital Hamamatsu Japan

Subclavian artery (SCA) injuries associated with central venous catheter (CVC) insertion are uncommon yet lethal complications that typically require surgical treatment. This case report presents the case of a 94-year-old man with an iatrogenic right SCA injury resulting from a misplaced CVC. Computed tomography revealed the catheter piercing the right internal jugular vein to enter the right SCA and then reaching the aortic arch. Emergent endovascular treatment was performed, and a 13-mm × 50-mm self-expanding Viabahn stent graft (W.L. Gore & Associates, Flagstaff, AZ, USA) was placed via the right brachial artery. The misplaced catheter was successfully removed under simultaneous postdeployment balloon dilatation. This case highlights the utility of the Viabahn stent graft for iatrogenic right SCA injury caused by a misplaced CVC and presents some insights and tips for a safer procedure.

关键词： Central Venous Catheter Insertion Iatrogenic Subclavian Artery Injury Viabahn Stent Graft Endovascular Treatment Surgical Techniques

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Morphological Change of Cocrystal Bis(8-Quinolinolato) Copper(II): 7,7,8,8-Tetracyanoquinodimethane Polymorphism

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Advances in Chemical Engineering and Science 2023年第1期13卷 1-6页

作者： Norihito Doki Minami Nomura masaaki Yokota Department of Chemistry and Bioengineering Faculty of Science and Engineering Iwate University Morioka Japan

We studied cocrystal of bis(8-quinolinolato) copper(II) (CuQ2) and 7,7,8,8-tetracyanoquinodimethane (TCNQ), which change dramatically crystal shape in a moment by adding press on crystal face. Single crystal was prepared by dissolving CuQ2 and TCNQ in chloroform by evaporation of the solution at ambient conditions. We investigated about crystal structure and morphological change properties. We proclaim that this phenomenon is solid phase transition to Form I from Form II, it is caused by pressure on the crystal face (001) of Form II and the crystal expansion direction is the side face (100). We take note of the common structure between polymorph and explain that this transition occurs by the structure like dominoes falling. We obtained a correlation between molecular level structure change and macroscopic shape changes.

关键词： Crystal Morphology Crystal Structure Organic Compounds

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Organic Melt Crystallization as a Method for Synthesis of Supramolecular Complexes

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Advances in Chemical Engineering and Science 2016年第2期6卷 76-81页

作者： masaaki Yokota Ryota Nakamura Norihito Doki Department of Chemistry and Bioengineering Iwate University Morioka Japan

The most simple method for solventless synthesis of supramolecular complex of CMCR·2BPY·BZP, [CMCR = C-methylcalix[4]resorcinarene, BPY = 4,4'-bipyridine, BZP = benzophenone], is proposed. Although CMCR by itself is high melting point compound (above 300°C), CMCR was found to be dissolved in melt mixture of BPY and BZPeven below 120°C. In the mixture of the three components, the reaction occurs to form CMCR·2BPY·BZP supramolecular complex.

关键词： Organic Melt Crystallization as a Method for Synthesis of Supramolecular Complexes

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用距离取样技术估算森林生境中的梅花鹿密度(英文)

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动物学报 2004年第1期50卷 27-31页

作者： Yuchun LI masaaki KOGANEZAWA Laboratory of Wildlife Management Faculty of Agriculture Ut sunomiya University 350 Mine-machiUtsunomiyaUtsunomiya University Forests Faculty of Agriculture Utsunomiya University Tochigi Prefecture321-8505Japan7556 FunyuShioya-machiShioya-gun Tochigi Prefecture329-2441 Ja pan

作者于 1999年 9、 10月在日本国日光国立公园的一个梅花鹿 (Cervusnippon)高密度区域实施了 16次夜间探照样带距离法取样调查。采用车载探照记数和激光测距仪测距 ,记录了梅花鹿的结群大小和距样带中心样线的垂直距离。应用距离取样技... 详细信息

作者于 1999年 9、 10月在日本国日光国立公园的一个梅花鹿 (Cervusnippon)高密度区域实施了 16次夜间探照样带距离法取样调查。采用车载探照记数和激光测距仪测距 ,记录了梅花鹿的结群大小和距样带中心样线的垂直距离。应用距离取样技术 (Distancesamplingtechnique ,DST)计算的结果表明 ,梅花鹿的密度为12 5 8头 /km2 (95%CI 10 0 7-157 3 ) ,在两侧 80m宽度的调查样带内梅花鹿的总发现率为 52 5% ;对线样带法的传统动物密度计算方法 (King s ,Hayne s ,Leopold s ,Gates sⅠ ,Gates sⅡ ,Gates sⅢ和Frye s方法 )的结果验证表明 ,这些传统密度计算方法过高估算梅花鹿的密度 ,其结果为距离取样技术 (DST)计算结果的 1 76(Frye′s法 ) -6 10 (Hayne′s法 )倍。因此 ,作者建议在使用线样带法测定动物密度时应尽量避免使用这些传统计算方法 ;不同地区间及同一地区不同季节间应用线样带法调查得到的动物个体记数值之间的比较存在偏差。

关键词：梅花鹿密度估计距离取样技术线样带法夜间探照记数

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