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Operative management of acute diverticulitis in immunosuppressed compared to immunocompetent patients: A systematic review

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World Journal of Surgical Procedures 2015年第1期5卷 155-166页

作者： Ahmed Al-Khamis Jad Abou Khalil Nazi Torabi Marie Demian Abbas Kezouh Philip H Gordon marylise boutros Division of Colorectal Surgery Jewish General HospitalMc Gill University Schulich Library of Science and Engineering Mc Gill University Department of Statistics and Epidemiology Jewish General Hospital

AIM: To determine short and long-term outcomes following operative management of acute diverticulitis in immunosuppressed(IMS) compared to immunocompetent(IMC) ***: PRISMA guidelines were followed in conducting this systematic review. We searched Pub Med(1946 to present), OVID MEDLINE(R) In-Process and Other Non-Indexed Citations, OVID MEDLINE(R) Daily and OVID MEDLINE(R)(1946 to present), EMBASE on OVID platform(1947 to present), CINAHL on EBSCO platform(1981 to present), and Cochrane Library using a systematic search strategy. There were no restrictions on publication date and language. We systematically reviewed all published cohort comparative studies, casecontrol studies, and randomized controlled trials that reported outcomes on operative management of acute episode of colonic diverticulitis in IMS in comparison to IMC patients. RESULTS: Seven hundred and fifty-five thousand five hundred and eighty-three patients were included in this systematic review; of which 1478 were IMS and 754105 were IMC patients. Of the nine studies included there was one prospective cohort, seven retrospective cohorts, one retrospective case-control study, and no randomized controlled trials. With the exception of solid organ transplant patients, IMS patients appeared to be older than IMC when they presented with an acuteepisode of diverticulitis. IMS patients presented with more severe acute diverticulitis and more insidious onset of symptoms than IMC patients. In the emergency setting, peritonitis was the main indication for operative intervention in both IMS and IMC patients. IMS patients were more likely to undergo Hartmann's procedure and less likely to undergo reconstructive procedures compared to IMC patients. Furthermore, IMS patients had higher morbidity and mortality rates in the emergency setting compared to IMC patients. In the elective settings, it appeared that reconstruction with primary anastomosis with or without a diverting loop stoma is the procedure o

关键词： Diverticular disease Immunosuppression Diverticulitis Chemotherapy Transplant Steroids

The Impact of Social Media on Dietary Behaviors and Body Image of College Students: A Qualitative Approach

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Food and Nutrition Sciences 2024年第8期15卷 711-726页

作者： Basem Azmy Saad boutros Tabbetha D. Lopez Valencia Browning-Keen Department of Human Sciences Sam Houston State University Huntsville TX USA

Background: The use of social media platforms for health and nutrition information has become popular among college students. Although social media made information readily accessible in different formats, nutritional misinformation promoted by influencers and non-experts caused negative impact on diet behavior and perception of body image. Previous research indicated that extensive use of social media was positively linked to disordered eating behaviors. Social media platforms like Facebook and Instagram that allow users to follow celebrities intensified exposure to influencers’ messages and images and resulted in negative moods and body dissatisfaction. Objective: This paper aims to explore the impact of social media on college students’ dietary behaviors and body image. Participants: 18 undergraduate students from a public university in the Southern United States were recruited through a mass email. Methods: A cross-sectional qualitative study of three focus groups was conducted. The focus groups were based on guiding open-ended questions. *** was used to code and analyze the data using inductive and deductive codes. Results: Three main themes were identified. The conditions theme included elements that explain why and how social media influences the participants’ actions. The actions theme included eating behavior, physical activity, and dietary supplement intake. The consequences theme describes anticipated or actual outcomes of actions such as body image and ideal weight. Conclusions: Social media has had a negative influence on diet behaviors and a positive influence on physical activity. Evidence-based nutrition and weight management information is needed to thwart potential misinformation.

关键词： Social Media Nutrition Information Dietary Behavior Body Image College Students

Physiotherapy Management of Rheumatic Diseases

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Open Journal of Rheumatology and Autoimmune Diseases 2024年第1期14卷 37-47页

作者： Aly Badra Kamissoko Abdoulaye Barry Mamadou Lamine Diallo boutros Cosme Nato Abdel Amide Gbadamassi Marie Traore Abèni Faouzyath Yaya Facely Traore Paul Eloundou Sory Diane Matènè Komara Halimatou Barry Moriba Toure Moriba Toure Kaba Conde Owonayo Oniankitan Department of Rheumatology Ignace Deen University Hospital Conakry Guinea Department of Rheumatology Sylvanus Olympio University Hospital Lome Togo Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon

Introduction: Physiotherapy is an integral part of the non-drug treatment strategy for rheumatological conditions. The evidence for its effects is not formal. The objective was to evaluate the impact of physiotherapy in the management of rheumatological disorders. Methods: 6-month case-control study (December 15, 2021 to June 20, 2022) at Ignace Deen University Hospital (Conakry). Patients with rheumatological disease who received drug therapy and physiotherapy were included in the case group. Age- and sex-matched controls had rheumatological conditions, treated without physiotherapy. The evaluation questionnaires were used: WOMAC (osteoarthritis), EIFEL (low back pain), NDI (neck pain), SPADI (shoulder). Patients with heart failure, respiratory failure and/or skin infection were not included. Results: We collected 773 patients (389 cases and 384 controls) with a mean age of 53.8 years ± 12.2 with female predominance (56.8%). Patients were mainly followed for osteoarthritis (65.2%). Rheumatological conditions managed were knee-based (119;30.6%), lumbar spine (220;56.6%), shoulders (27;6.9%) and cervical spine (23;5.9%). For an average duration of 53.4 ± 12.2 minutes per session, patients had benefited from a median of 19 physiotherapy sessions. After 3 months, the baseline mean VAS of 6/10 improved to 2.2 ± 1.6 for cases and 5.7 ± 1.2 for controls. Functional capacity was improved (WOMAC: 41.8 ± 22.7 vs. 18.3 ± 7.3). The satisfaction of patients treated with physiotherapy was 20 times higher than in controls. Conclusion: Physiotherapy performed in the management of rheumatological conditions significantly reduced pain and improved functional capacity.

关键词： Rheumatological Disease Physiotherapy WOMAC Guinea

Surgical Anatomy Around the Orbit: The System of Zones: A Continuation of Surgical Anatomy of the Orbit by Barry M. Zide and Glenn W. Jelks

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Management of Post-Mastectomy Radio-Necrotic Ulcers &Osteoradionecrosis

丛书名： Includes CD-ROM

2006年

作者： boutros Sean G. Luce Craig A. Millman Arthur L. Zide Barry M

来源：畅想之星图书光盘版（南... 评论

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Journal of Cancer Therapy 2019年第6期10卷 433-441页

作者： Alaadin Hussein Rimoun boutros Amani Saber Surgical Oncology Department National Cancer Institute Cairo University Cairo Egypt Radiotherapy Department National Cancer Institute Cairo University Cairo Egypt Clinical Oncology Department Minia Oncology Center Minia University Minia Egypt

Background: Breast cancer is still the most common indication for chest wall irradiation, despite the advances in RTH techniques complications still occur, and the time of its occurrence vary and could take few months to many years. ORN usually manifests with pain, exposed bone, fistulae and pathological fracture and the proper management needs proper debridement and coverage by thick musculocutaneous flaps. Objective: To evaluate different techniques of surgical management of post-irradiation persistent radio-necrotic ulcer & ORN with emphasis on the outcome of each technique. Patients and methods: A retrospective study from 2010 to 2015 reviewed 20 patients subjected to post-mastectomy radiotherapy as a treatment for breast cancer inNCICairo, and Minia oncology center Hospital, Egypt. Cases were biopsied to exclude local recurrence. The age, sex, type of ulcer, dose of radiotherapy received and the management done for these cases were recorded. Results: Only 4 patients responded to conservative treatment in the form of repeated dressings, and 16 patients needed surgical treatment;5 of them were treated with debridement and coverage with split thickness graft with high rate of complications reaching 80%, the other 11 patients were reconstructed with musculocutanoeus flaps, of these 7 patients were reconstructed with LD flaps with 57.14% success rate and minor complications only, the other 4 cases were reconstructed with TRAM flap with 50% success and major loss of the flap in one case that needed salvage by LD flap. Pre-operative comorbidity was found in 6 patients and all of them experienced complications while only 3 of the other 14 who had no comorbidity had postoperative complications. Conclusion: Pedicled flaps provide a good choice for reconstruction and provide chest wall support without the use of synthetic mesh.

关键词： Radionecrotic Ulcer Osteoradionecrosis Pedicled Myo-Cutaneous Flaps Breast Cancer

Early plasmapheresis and rituximab for acute humoral rejection after ABO-compatible liver transplantation

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World Journal of Gastroenterology 2009年第27期15卷 3426-3430页

作者： Nassim Kamar Laurence Lavayssière Fabrice Muscari Janick Selves Céline Guilbeau-Frugier Isabelle Cardeau Laure Esposito Olivier Cointault Marie Béatrice Nogier Jean Marie Peron Philippe Otal marylise Fort Lionel Rostaing Department of Nephrology Dialysis and Multi-Organ Transplantation CHU RangueilTSA 50032 31059 Toulouse Cédex 9 France INSERM U858 IFR 31 CHU Rangueil TSA 50032 31059 Toulouse Cédex 9 France Department of Liver Transplantation CHU RangueilTSA 50032 31059 Toulouse Cédex 9 France Department of Histopathology CHU PurpanTSA 50032 31059 Toulouse Cédex 9 France Department of Histopathology CHU RangueilTSA 50032 31059 Toulouse Cédex 9 France Department of Histopathology CHU PurpanTSA 50032 31059 Toulouse Cédex 9 France Department of Radiology CHU RangueilTSA 50032 31059 Toulouse Cédex 9 France Department of Immunology CHU RangueilTSA 50032 31059 Toulouse Cédex 9 France INSERM U563 IFR 30 CHU PurpanTSA 50032 31059 Toulouse Cédex 9 France

Acute humoral rejection （AHR） is uncommon after ABO- compatible liver transplantation. Herein, we report two cases of AHR treated with plasmapheresis and rituximab in two ABO-compatible liver-transplant patients with preformed anti-human leukocyte antigen donor-specific antibodies. Patient 1 experienced a biopsy-proven AHR at day 10 post-transplant. She was treated by steroid pulses, and OKT3. Because of persisting signs of biopsy-proven AHR at day 26, she was treated by plasmapheresis and rituximab. Uver enzyme levels did not improve, and she died on day 41. Patient 2 experienced a biopsy-proven AHR on day 10 post-transplant. She was treated by steroid pulses, plasmapheresis, and rituximab. Liver enzymes returned to within normal range 18 d after diagnosis. Uver biopsies, at 3 and 9 mo post-transplant, showed complete resolution of AHR. We conclude that plasmapheresis should be started as soon as AHR is diagnosed, and be associated with a B-cell depleting agent. Rituximab may be considered as a first-line therapy.

关键词： Acute humoral rejection Liver transplantation Donor-specific antibodies Rituximab Plasmapheresis

Wearable positive end-expiratory pressure valve improves exercise performance

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Sports Medicine and Health Science 2020年第3期2卷 159-165页

作者： Stephen F.Crouse Jason R.Lytle Sean boutros William Benton Michael Moreno Patrick C.McCulloch Brad S.Lambert Department of Health and Kinesiology Texas A&M UniversityCollege StationTXUSA My Houston Surgeons 9230 Katy FreewaySuite 600HoustonTXUSA PEEP Performance LLC.96 Siwanoy BlvdEastchesterNYUSA Department of Mechanical Engineering Texas A&M UniversityCollege StationTXUSA Houston Methodist Hospital HoustonTXUSA

We tested a PEEP(4.2 cmH_(2)O)mouthpiece(PMP)on maximal cycling performance in healthy ***-1,PMP ***-PMP mouthpiece(CON)[n=9(5♂),Age=30±2 yr];Experiment-2,PMP *** mouthpiece(NMP)[n=10(7♂),Age=27±1 yr].At timepoint 1 in both experiments(mouthpiece condition randomized)subjects performed graded cycling testing(GXT)(Corival®cycle ergometer)to determine VO_(2peak)(ml*kg*min^(-1)),O2pulse(mlO2*bt^(-1)),GXT endurance time(GXT-T(s)),and VO_(2)(ml*kg*min^(-1))-at-ventilatory-threshold(VO_(2)@VT).At timepoint 272 h later,subjects completed a ventilatory-threshold-endurance-ride[VTER(s)]timed to exhaustion at VO_(2)@VT power(W).One week later at timepoints 3 and 4(time-of-day controlled),subjects repeated testing protocols under the alternate mouthpiece *** results(paired T-test,p<0.05):Experiment 1 PMP ***,respectively:VO_(2peak)=45.2±2.4 vs.42.4±2.3 p<0.05;VO_(2)@VT=33.7±2.0 vs.32.3±1.6;GXTTTE=521.7±73.4 vs.495.3±72.8(p<0.05);VTER=846.2±166.0 vs.743.1±124.7;O2pulse=24.5±1.4 vs.23.1±1.3(p<0.05).Experiment 2 PMP ***,respectively:VO_(2peak)=43.3±1.6 vs.41.7±1.6(p<0.05);VO_(2)@VT=31.1±1.2 vs.29.1±1.3(p<0.05);GXT-TTE=511.7±49.6 vs.486.4±49.6(p<0.05);VTER 872.4±134.0 vs.792.9±122.4;O2pulse=24.1±0.9 vs.23.4±0.9(p<0.05).Results demonstrate that the PMP conferred a significant performance benefit to cyclists completing high intensity cycling exercise.

关键词： Oxygen uptake Cycling exercise Pulmonary system Maximal working capacity Oxygen saturation Respiration

Synergetic role of integrating the departments of cancer registry and clinical research at an academic comprehensive cancer center

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World Journal of Methodology 2017年第2期7卷 33-36页

作者： McKenzie Bedra Tammy Vyskocil Jennifer Emel Crystal Edwards Cherif boutros Tate Cancer Center University of Maryland Baltimore Washington Medical Center Department of Surgery University of Maryland School of Medicine

Integration of the cancer registry and clinical research departments can have a significant impact on the accreditation process of a Commission on Cancer(Co C) *** in we demonstrate that the integration of both departments will benefit as there is increased knowledge, manpower and crossover in job responsibilities in our Co C-accredited Academic Comprehensive Cancer *** our model this integration has led to a more successful cooperative interaction among departments, which has in turn created an enhanced combined effect on overall output and *** manpower for the cancer registry has led to increased caseloads, decreased time from date of first contact to abstraction, quality of data submissions, and timely follow-up of all patients from our reference date for accurate survival analysis along with completeness of *** 2016, our Annual Facility report showed an additional 163 cases over prediction by the state of Maryland Cancer Registry and a 39% increase in case *** proof of the synergetic effectiveness of our model within one year of its implementation, the cancer center was able to apply for, and was awarded membership from Alliance for Clinical Trials in Oncology, Central IRB, and in turn led to increased clinical trial accrual from 2.8% in 2014 compared to 13.2% *** cancer registry in year one submitted over 150 more cases than predicted, improved quality outcome measures displayed by our Cancer Program Practice Profile reports and had more timely and complete data submissions to national and state *** synergetic integration has led to a better understanding, utilization and analysis of data by an integrated team with Clinical Research expertise.

关键词： Cancer registry Clinical research Commission on Cancer Synergetic integration American College of Surgeons

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金边的微笑

南风窗 2016年第3期 58-63页

作者：谢奕秋 marylise Vigneau Anzenberger 东方IC

柬埔寨首都Phnom Penh,读作"百囊奔",意为"奔夫人之山",华侨称之为"金边"。金边有过太多不幸,然而最大的不幸并非受外国统治,而是被本国的"红色高棉"清空整座城市,去建设虚无缥缈的农业乌托邦。外国游客到金边,看完常规景点,嘟嘟车司机... 详细信息

柬埔寨首都Phnom Penh,读作"百囊奔",意为"奔夫人之山",华侨称之为"金边"。金边有过太多不幸,然而最大的不幸并非受外国统治,而是被本国的"红色高棉"清空整座城市,去建设虚无缥缈的农业乌托邦。外国游客到金边,看完常规景点,嘟嘟车司机会推荐他们去南郊的万人冢参观。40年前的伤口,金边人已经不介意裸露给外人看。在柬埔寨北部的暹粒市,巴戎寺里的49座微笑着的古老四面佛,有"高棉的微笑"之誉。而金边的微笑,是一座半现代半古老城市,基于和解夙愿及发展梦想的自然表情。

关键词：红色高棉微笑