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World Journal of Pediatrics 2022年第6期18卷 443-448页

作者： Eman R.Youness Sherien MEl-Daly Hanaa Reyad Abdallah Hala T.El-Bassyouni Hisham Megahed Azzah A.Khedr marwa elhady Walaa Alsharany Abuelhamd Medical Biochemistry Department Medical Research DivisionNational Research CentreGizaEgypt Biological Anthropology Department Medical Research DivisionNational Research CentreGizaEgypt Clinical Genetics Department Human Genetics and Genome Research DivisionNational Research CentreEl-Tahrir StreetPO:12622GizaEgypt Human Cytogenetics Department Human Genetics and Genome Research DivisionNational Research CentreGizaEgypt Pediatric Department Faculty of Medicine for GirlsAl-Azhar UniversityCairoEgypt Department of Pediatrics Faculty of MedicineCairo UniversityCairoEgypt

Down syndrome,Turner syndrome,and Klinefelter syndrome are the most common chromosomal disorders *** syndrome is caused by an extra copy of the 21st chromosome and has an incidence of 1 in 800 to 1000 live *** syndrom... 详细信息

关键词： chromosomal Turner Serum

Thermal noise-driven resonant sensors

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Microsystems & Nanoengineering 2024年第3期10卷 259-271页

作者： Yan Qiao Alaaeldin elhady Mohamed Arabi Eihab Abdel-Rahman Wenming Zhang School of Mechanical Engineering Shanghai Jiao Tong UniversityShanghaiChina Department of Systems Design Engineering University of WaterlooWaterlooONCanada

MEMS/NEMS resonant sensors hold promise for minute mass and force ***,one major challenge is that conventional externally driven sensors inevitably encounter undesired intrinsic noise,which imposes a fundamental limitation upon their signal-to-noise ratio(SNR)and,consequently,the ***,this restriction becomes increasingly pronounced as sensors shrink to the *** this work,we propose a counterintuitive paradigm shift that turns intrinsic thermal noise from an impediment to a constituent of the sensor by harvesting it as the driving force,obviating the need for external actuation and realizing‘noise-driven’*** sensors employ the dynamically amplified response to thermal noise at resonances for stimulus *** demonstrate that lightly damped and highly compliant nano-structures with high aspect ratios are promising candidates for this class of *** overcome the phase incoherence of the drive force,three noise-enabled quantitative sensing mechanisms are *** validated our sensor paradigm by experimental demonstrating noise-driven pressure and temperature ***-driven sensors offer a new opportunity for delivering practical NEMS sensors that can function at room temperature and under ambient pressure,and a development that suggests a path to cheaper,simpler,and low-power-consumption sensors.

关键词： noise resonant overcome

Unraveling the nature of sensing in electrostatic MEMS gas sensors

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Microsystems & Nanoengineering 2024年第3期10卷 109-117页

作者： Yasser S.Shama Sasan Rahmanian Hamza Mouharrar Rana Abdelrahman Alaaeldin elhady Eihab M.Abdel-Rahman Systems Design Engineering University of Waterloo200 University Ave WWaterloo N2L 3G1 ONCanada Mechanical Engineering Benha Faculty of EngineeringBenha UniversityBenha 13511Egypt

This paper investigates the fundamental sensing mechanism of electrostatic MEMS gas *** compares among the responsivities of a set of MEMS isopropanol sensors before and after functionalization,and in the presence and absence of electrostatic fields when operated in static and dynamic detection *** the static mode,we found that the sensors do not exhibit a measurable change in displacement due to added *** the other hand,bare sensors showed a clear change in displacement in response to isopropanol *** the dynamic mode,functionalized sensors showed a measurable frequency shift due to the added mass of isopropanol *** the presence of strong electrostatic fields,the measured frequency shift was found to be threefold larger than that in their absence in response to the same concentration of isopropanol *** enhanced responsivity of dynamic detection allows the sensors to measure the vapor mass captured by the functional material,which is not the case for static *** detection of isopropanol by bare sensors in static mode shows that change in the medium permittivity is the primary sensing *** enhanced responsivity of dynamic mode sensors when operated in strong electrostatic fields shows that their sensing mechanism is a combination of a weaker added mass effect and a stronger permittivity *** findings show that electrostatic MEMS gas sensors are independent of the direction of the gravitational field and are,thus,robust to changes in *** is erroneous to refer to them as‘gravimetric’sensors.

关键词： mechanism. electrostatic measurable

Controlling Remote Robots Based on Zidan’s Quantum Computing Model

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Computers, Materials & Continua 2022年第12期73卷 6225-6236页

作者： Biswaranjan Panda Nitin Kumar Tripathy Shibashankar Sahu Bikash K.Behera Walaa E.elhady Indian Institute of Science Education and Research Berhampur760005India Bikash’s Quantum(OPC)Private Limited BalindiMohanpur741246West BengalIndia Faculty of Computers and Information Technology The National Egyptian E-Learning UniversityCairoEgypt

In this paper,we propose a novel algorithm based on Zidan’s quantum computing model for remotely controlling the direction of a quantumcontrolledmobile robot equippedwith *** proposed algorithm is based on the measurement of concurrence value for the different movements of the *** a faraway robot that moves in the deep space(e.g.,moves toward a galaxy),and it is required to control the direction of this robot from a ground station by some person *** sends an unknown qubitα|0)+β|1)via the teleportation protocol to the ***,the proposed algorithm decodes the received unknown qubit into an angleθ,that determines the motion direction of the robot,based on the concurrence *** proposed algorithm has been tested for four and eight *** simulators have been tested;IBM Quantum composer and IBM’s system,The two simulators achieved the same result *** motion of any part of the robot is considered,if it has a pre-existing sensor system and a locomotive system,.We can use this technique in many places like in space robots(16 directions).The results show that the proposed technique can be easily used for a huge number of ***,increasing the number of movements of the robot will increase the number of qubits.

关键词： Quantum neural network competitive learning swap test quantum robots

Eye Detection-Based Deep Belief Neural Networks and Speeded-Up Robust Feature Algorithm

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Computer Systems Science & Engineering 2023年第6期45卷 3195-3213页

作者： Zahraa Tarek Samaa M.Shohieb Abdelghafar M.elhady El-Sayed M.El-kenawy Mahmoud Y.Shams Faculty of Computers and Information Mansoura UniversityMansoura35516Egypt Deanship of Scientific Research Umm Al-Qura UniversityMakkah21955KSA Delta Higher Institute of Engineering and Technology Mansoura35111Egypt Faculty of Artificial Intelligence Kafrelsheikh UniversityKafrelsheikh33511Egypt

The ability to detect and localize the human eye is critical for use in security applications and human identification and verification *** is because eye recognition algorithms have multiple challenges,such as multi-pose variations,ocular parts,and ***,the modern security applica-tions fail to detect facial expressions from eye *** this paper,a Speeded-Up Roust Feature(SURF)Algorithm was utilized to localize the face images of the enrolled *** highlighted on eye and pupil parts to be detected based on SURF,Hough Circle Transform(HCT),and Local Binary Pattern(LBP).Afterward,Deep Belief Neural Networks(DBNN)were used to classify the input features results from the SURF *** further determined the correctly and wrongly classified subjects using a confusion matrix with two class labels to classify people whose eye images are correctly *** apply Stochastic Gradient Descent(SGD)optimizer to address the overfitting problem,and the hyper-parameters arefine-tuned based on the applied *** accuracy of the proposed system is determined based on SURF,LBP,and DBNN classifier achieved 95.54%for the ORL dataset,94.07%for the BioID,and 96.20%for the CASIA-V5 *** proposed approach is more reliable and more advanced when compared with state-of-the-art algorithms.

关键词： Eye localization classification DBNN detection feature extraction LBP feature extraction SURF

Power frequency AC voltage measurement based on double wound Rogowski coil

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High Voltage 2017年第2期2卷 129-135页

作者： Mohamed E.Ibrahim Amr M.Abd-elhady High Voltage and Dielectric Materials Lab. Faculty of EngineeringMenoufia UniversityShebin El_Kom 32511Egypt

This study presents a technique for power frequency AC voltage *** proposed technique utilises a capacitor having a low capacitance in addition to a double wound Rogowski *** technique depends on capacitor current measurement using the double wound Rogowski *** voltage across the capacitor that connected in parallel with the system at which AC voltage is intended to be measured is *** proposed technique is experimentally evaluated by designing the measurement system and using a digital signal processing board for the reconstruction ***,the experimental results based on Rogowski coil measurements are compared with those obtained from reference ***,the obtained results validate the efficacy of the proposed technique in power frequency AC voltage measurement.

关键词： Rogowski double capacitance

Frequency unlocking-based MEMS bifurcation sensors

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微系统与纳米工程(英文) 2023年第3期9卷 171-181页

作者： Yan Qiao Zhan Shi Yutao Xu Xueyong Wei Alaaeldin elhady Eihab Abdel-Rahman Ronghua Huan Wenming Zhang State Key Laboratory of Mechanical System and Vibration School of Mechanical EngineeringShanghai Jiao Tong UniversityShanghaiChina Department of Mechanics Key Laboratory of Soft Machines and Smart Devices of Zhejiang ProvinceZhejiang UniversityHangzhouChina State Key Laboratory for Manufacturing Systems Engineering Xi’an Jiaotong UniversityXi’anChina Department of Systems Design Engineering University of WaterlooWaterlooONCanada

MEMS resonators exhibit rich dynamic behaviors under the internal resonance regime. In this work, we present a novel MEMS bifurcation sensor that exploits frequency unlocking due to a 1:3 internal resonance between two electrostatically coupled micro-resonators. The proposed detection mechanism allows the sensor to operate in binary (digital) and analog modes, depending on whether the sensor merely detects a significant jump event in the peak frequency upon unlocking or measures the shift in the peak frequency after unlocking and uses it in conjunction with a calibration curve to estimate the corresponding change in stimulus. We validate the success of this sensor paradigm by experimentally demonstrating charge detection. High charge resolutions are achieved in binary mode, up to 0.137 fC, and in analog mode, up to 0.01 fC. The proposed binary sensor enables extraordinarily high detection resolutions due to the excellent frequency stability under internal resonance and the high signal-to-noise ratio of the shift in peak frequency. Our findings offer new opportunities for high-performance ultrasensitive sensors.

关键词： locking bifurcation binary

Tumor necrosis factor-α-G308A polymorphism is associated with liver pathological changes in hepatitis C virus patients

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World Journal of Gastroenterology 2016年第34期22卷 7767-7777页

作者： Noha G Bader El Din Sally Farouk Reem El-Shenawy marwa K Ibrahim Reham M Dawood Mostafa M elhady Ahmed M Salem Naglaa Zayed Ahmed Khairy Mostafa K El Awady Department of Microbial Biotechnology National Research Centre Department of Biochemistry Faculty of ScienceAin Shams University Endemic Medicine Department Faculty of MedicineCairo University

AIM To investigate the association of tumor necrosis factor alpha(TNFα)-G308 A polymorphism with different liver pathological changes in treatment-na?ve Egyptian patients infected with hepatitis C virus(HCV) genotype *** This study included 180 subjects,composed of 120 treatment-na?ve chronic HCV patients with different fibrosis grades(F0-F4) and 60 healthy controls. The TNFα-G308 A region was amplified by PCR and the different genotypes were detected by restriction fragment length polymorphism analysis. The TNFα protein was detected by enzyme-linked immunosorbent assay. The influence of different TNFα-G308 A genotypes on TNFα expression and liver disease progression were statistically analyzed. The OR and 95%CI were calculated to assess the relative risk *** Current data showed that the TNFα-G308 A SNP frequency was significantly different between controls and HCV infected patients(P = 0.001). Both the AA genotype and A allele were significantly higher in late fibrosis patients(F2-F4,n = 60) than in early fibrosis patients(F0-F1,n = 60)(P = 0.05,0.04 respectively). Moreover,the GA or AA genotypes increased the TNFα serum level greater than the GG genotype(P = 0.002). The results showed a clear association between severe liver pathological conditions(inflammation,steatosis and fibrosis) and(GA + AA) genotypes(P = 0.035,0.03,0.04 respectively). The stepwise logistic regression analysis showed that the TNFα genotypes(GA + AA) were significantly associated with liver inflammation(OR = 3.776,95%CI: 1.399-10.194,P = 0.009),severe steatosis(OR = 4.49,95%CI: 1.441-14.0,P = 0.010) and fibrosis progression(OR = 2.84,95%CI: 1.080-7.472,P = 0.034). Also,the A allele was an independent risk factor for liver inflammation(P = 0.003),steatosis(P = 0.003) and fibrosis(P = 0.014). CONCLUSION TNFα SNP at nucleotide-308 represents an important genetic marker that can be used for the prognosis of different liver pathological changes in HCV infected

关键词： Hepatitis C virus immune response Tumor necrosis factor alpha Single nucleotide polymorphisms Cytokine expression Liver disease progression

Chemo-resistant gestational trophoblastic neoplasia, 5-years experience of Mansoura University Hospital, Egypt

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Open Journal of Obstetrics and Gynecology 2011年第3期1卷 153-157页

作者： Reda Abd elhady Hemida Eman Toson Hend Shalaby Ehsan Refaie Doaa Sharaf Eldin 不详

Introduction: Gestational trophoblastic neoplasia (GTN), is recognized as the most curable gynaecologic malignancy. However, many cases are resistant to first line chemotherapy. Objective: The aim of the study is to report our 5 years experience in the management of GTN cases with special stress on the chemo-resistant cases. Methods: The study was performed through reviewing the records of 51 patients who were diagnosed as GTN during the period from 1/1/2006 to 31/12/2010 in Mansoura University Hospital, Egypt. Results: Resistance to methotrexate therapy was reported in 15.15% of low risk cases and received etoposide or cisplatinum/etoposide. Sixty percent of high risk cases were resistant to MAC combination and received salvage chemotherapy or hysterectomy. There was significant correlation between patient response and initial B-hCG, as well as WHO risk score (P value = 0.001 in both) but correlations with age, parity, type of antecedent pregnancy, and histopathology were non significant (p = 0.95, 0.53, 0.47& 0.83 respectively). Conclusion: Low risk GTN cases who were resistant to methotrexate monotherapy received etoposide or cisplatinum/etoposide as a second-line therapy. High risk GTN cases who were resistant to MAC combination received second-line combination chemotherapy and/or hysterectomy. WHO risk score and initial B-hCG were correlated to resistance to first line chemotherapy.

关键词： Gestational trophoblastic neoplasia-chemotherapy-resistance